WO2004041830A3 - Procede ameliore de preparation de biotine - Google Patents

Procede ameliore de preparation de biotine Download PDF

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Publication number
WO2004041830A3
WO2004041830A3 PCT/IB2003/004974 IB0304974W WO2004041830A3 WO 2004041830 A3 WO2004041830 A3 WO 2004041830A3 IB 0304974 W IB0304974 W IB 0304974W WO 2004041830 A3 WO2004041830 A3 WO 2004041830A3
Authority
WO
WIPO (PCT)
Prior art keywords
biotin
preparation
improved process
formula
optically active
Prior art date
Application number
PCT/IB2003/004974
Other languages
English (en)
Other versions
WO2004041830A2 (fr
Inventor
Pandurang Balwant Deshpande
Anil Ganpat Holkar
Sanjay Nivrutti Karale
Wajid Sajjad Jafri
Gautam Kumar Das
Original Assignee
Orchid Chemicals & Pharm Ltd
Pandurang Balwant Deshpande
Anil Ganpat Holkar
Sanjay Nivrutti Karale
Wajid Sajjad Jafri
Gautam Kumar Das
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals & Pharm Ltd, Pandurang Balwant Deshpande, Anil Ganpat Holkar, Sanjay Nivrutti Karale, Wajid Sajjad Jafri, Gautam Kumar Das filed Critical Orchid Chemicals & Pharm Ltd
Priority to AU2003276510A priority Critical patent/AU2003276510A1/en
Publication of WO2004041830A2 publication Critical patent/WO2004041830A2/fr
Publication of WO2004041830A3 publication Critical patent/WO2004041830A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

La présente invention concerne un procédé amélioré de préparation de biotine (+) active optiquement de formule (I) à l'état pur.
PCT/IB2003/004974 2002-11-07 2003-11-06 Procede ameliore de preparation de biotine WO2004041830A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003276510A AU2003276510A1 (en) 2002-11-07 2003-11-06 An improved process for the preparation of biotin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN815/MAS/2002 2002-11-07
IN815CH2002 2002-11-07

Publications (2)

Publication Number Publication Date
WO2004041830A2 WO2004041830A2 (fr) 2004-05-21
WO2004041830A3 true WO2004041830A3 (fr) 2005-05-26

Family

ID=32310093

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2003/004974 WO2004041830A2 (fr) 2002-11-07 2003-11-06 Procede ameliore de preparation de biotine

Country Status (2)

Country Link
AU (1) AU2003276510A1 (fr)
WO (1) WO2004041830A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101195629B (zh) * 2006-12-05 2010-05-19 浙江医药股份有限公司新昌制药厂 d-生物素的纯化方法
CN104710437B (zh) * 2015-04-04 2017-01-25 富阳科兴生物化工有限公司 一种双苄生物素脱苄制d‑生物素的改进方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2489238A (en) * 1948-06-08 1949-11-22 Hoffmann La Roche Debenzylation of benzylated imidazolido-thiophane compounds
WO1998043979A1 (fr) * 1997-03-27 1998-10-08 Merck Patent Gmbh Procede de debenzylation de biotine de dibenzyle
DE19962661A1 (de) * 1998-12-24 2000-06-29 Sumitomo Chemical Co Verfahren zur Herstellung von Hexahydro-2-oxo-1H-thieno[3,4-d]-imidazol-4-pentansäure
CN1374312A (zh) * 2002-03-27 2002-10-16 复旦大学 d－生物素的合成方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2489238A (en) * 1948-06-08 1949-11-22 Hoffmann La Roche Debenzylation of benzylated imidazolido-thiophane compounds
WO1998043979A1 (fr) * 1997-03-27 1998-10-08 Merck Patent Gmbh Procede de debenzylation de biotine de dibenzyle
DE19962661A1 (de) * 1998-12-24 2000-06-29 Sumitomo Chemical Co Verfahren zur Herstellung von Hexahydro-2-oxo-1H-thieno[3,4-d]-imidazol-4-pentansäure
CN1374312A (zh) * 2002-03-27 2002-10-16 复旦大学 d－生物素的合成方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEN F-E ET AL: "Synthetic Studies on d-Biotin, Part 6:An Expeditious and Enantiocontrolled Approach to the Total Synthesis of d-Biotin via a Polymer-Supported Chiral Oxazaborolidine-Catalyzed Reduction of meso-Cyclic Imide Strategy", SYNTHESIS 2003 GERMANY, no. 14, 2003, pages 2155 - 2160, XP002278550, ISSN: 0039-7881 *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2002, XP002278544, retrieved from STN Database accession no. 140:181254 *
POPSAVIN VELIMIR ET AL: "An efficient synthesis of (+)-oxybiotin from D-arabinose", TETRAHEDRON LETTERS, vol. 43, no. 12, 18 March 2002 (2002-03-18), pages 2281 - 2284, XP002278543, ISSN: 0040-4039 *

Also Published As

Publication number Publication date
AU2003276510A1 (en) 2004-06-07
WO2004041830A2 (fr) 2004-05-21

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