WO2004020599A3 - Antagonistes de la voie hedgehog, methodes et applications correspondantes - Google Patents

Antagonistes de la voie hedgehog, methodes et applications correspondantes Download PDF

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Publication number
WO2004020599A3
WO2004020599A3 PCT/US2003/027279 US0327279W WO2004020599A3 WO 2004020599 A3 WO2004020599 A3 WO 2004020599A3 US 0327279 W US0327279 W US 0327279W WO 2004020599 A3 WO2004020599 A3 WO 2004020599A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
hedgehog antagonists
uses related
hedgehog pathway
inhibiting
Prior art date
Application number
PCT/US2003/027279
Other languages
English (en)
Other versions
WO2004020599A2 (fr
Inventor
Henryk K Dudek
Irina Karavanov
Carmen Pepicelli
Lee Rubin
Karen Kotkow
Original Assignee
Curis Inc
Henryk K Dudek
Irina Karavanov
Carmen Pepicelli
Lee Rubin
Karen Kotkow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curis Inc, Henryk K Dudek, Irina Karavanov, Carmen Pepicelli, Lee Rubin, Karen Kotkow filed Critical Curis Inc
Priority to AU2003265853A priority Critical patent/AU2003265853A1/en
Publication of WO2004020599A2 publication Critical patent/WO2004020599A2/fr
Publication of WO2004020599A3 publication Critical patent/WO2004020599A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La présente invention concerne des compositions et des méthodes destinées à l'inhibition de l'angiogenèse et au traitement ou à la prévention de la prolifération cellulaire anormale, y compris des tumeurs, ces méthodes consistant à inhiber la voie hedgehog, à l'aide d'un des antagonistes de la voie hedgehog décrit dans la partie descriptive de la présente demande, par exemple.
PCT/US2003/027279 2002-08-29 2003-08-29 Antagonistes de la voie hedgehog, methodes et applications correspondantes WO2004020599A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003265853A AU2003265853A1 (en) 2002-08-29 2003-08-29 Hedgehog antagonists, methods and uses related thereto

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40714502P 2002-08-29 2002-08-29
US60/407,145 2002-08-29

Publications (2)

Publication Number Publication Date
WO2004020599A2 WO2004020599A2 (fr) 2004-03-11
WO2004020599A3 true WO2004020599A3 (fr) 2006-12-28

Family

ID=31978427

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/027279 WO2004020599A2 (fr) 2002-08-29 2003-08-29 Antagonistes de la voie hedgehog, methodes et applications correspondantes

Country Status (2)

Country Link
AU (1) AU2003265853A1 (fr)
WO (1) WO2004020599A2 (fr)

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US9290497B2 (en) 2011-01-10 2016-03-22 Infinity Pharmaceuticals, Inc. Processes for preparing isoquinolinones and solid forms of isoquinolinones

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9290497B2 (en) 2011-01-10 2016-03-22 Infinity Pharmaceuticals, Inc. Processes for preparing isoquinolinones and solid forms of isoquinolinones

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Publication number Publication date
WO2004020599A2 (fr) 2004-03-11
AU2003265853A1 (en) 2004-03-19
AU2003265853A8 (en) 2004-03-19

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