WO2003104811A3 - Utilisation diagnostique et therapeutique de la proteine regulatrice de reponse steroidogene aigue pour traiter des maladies neurodegeneratives - Google Patents
Utilisation diagnostique et therapeutique de la proteine regulatrice de reponse steroidogene aigue pour traiter des maladies neurodegeneratives Download PDFInfo
- Publication number
- WO2003104811A3 WO2003104811A3 PCT/EP2003/005910 EP0305910W WO03104811A3 WO 2003104811 A3 WO2003104811 A3 WO 2003104811A3 EP 0305910 W EP0305910 W EP 0305910W WO 03104811 A3 WO03104811 A3 WO 03104811A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disease
- regulatory protein
- neurodegenerative diseases
- diagnostic
- therapeutic use
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 4
- 102000049867 Steroidogenic acute regulatory protein Human genes 0.000 title abstract 3
- 108010018411 Steroidogenic acute regulatory protein Proteins 0.000 title abstract 3
- 230000004770 neurodegeneration Effects 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 101150078937 STAR gene Proteins 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004511831A JP2005531305A (ja) | 2002-06-10 | 2003-06-05 | ステロイド産生急性調節タンパク質の神経変性疾患に関する診断的および治療的使用 |
AU2003240746A AU2003240746A1 (en) | 2002-06-10 | 2003-06-05 | Diagnostic and therapeutic use of steroidogenic acute regulatory protein for neurodegenerative diseases |
EP03730155A EP1512013A2 (fr) | 2002-06-10 | 2003-06-05 | Utilisation diagnostique et therapeutique de la proteine regulatrice de reponse steroidogene aigue pour traiter des maladies neurodegeneratives |
US10/517,439 US20070118913A1 (en) | 2002-05-17 | 2003-06-05 | Diagnostic and therapeutic use of steroidogenic acute regulatory protein for neurodegenerative diseases |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38672102P | 2002-06-10 | 2002-06-10 | |
EP02012815 | 2002-06-10 | ||
US60/386,721 | 2002-06-10 | ||
EP02012815.3 | 2002-06-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003104811A2 WO2003104811A2 (fr) | 2003-12-18 |
WO2003104811A3 true WO2003104811A3 (fr) | 2004-10-14 |
Family
ID=56290436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/005910 WO2003104811A2 (fr) | 2002-05-17 | 2003-06-05 | Utilisation diagnostique et therapeutique de la proteine regulatrice de reponse steroidogene aigue pour traiter des maladies neurodegeneratives |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1512013A2 (fr) |
JP (1) | JP2005531305A (fr) |
AU (1) | AU2003240746A1 (fr) |
WO (1) | WO2003104811A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024005187A1 (fr) * | 2022-07-01 | 2024-01-04 | 田辺三菱製薬株式会社 | Composition et procédé d'évaluation de la réactivité de l'édaravone |
KR20240035189A (ko) * | 2022-09-08 | 2024-03-15 | 차의과학대학교 산학협력단 | 고령 여성의 난임 진단을 위한 바이오마커 및 이의 용도 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5556847A (en) * | 1994-10-27 | 1996-09-17 | Duquesne University Of The Holy Ghost | Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors |
WO1999052519A2 (fr) * | 1998-04-14 | 1999-10-21 | The General Hospital Corporation | Methodes de traitement de troubles neuropsychiatriques |
WO2000066728A1 (fr) * | 1999-05-03 | 2000-11-09 | Compugen Ltd. | Homologues de star |
WO2001032920A2 (fr) * | 1999-11-03 | 2001-05-10 | Metris Therapeutics Limited | Agents impliques dans l'endometriose |
-
2003
- 2003-06-05 EP EP03730155A patent/EP1512013A2/fr not_active Withdrawn
- 2003-06-05 WO PCT/EP2003/005910 patent/WO2003104811A2/fr active Application Filing
- 2003-06-05 JP JP2004511831A patent/JP2005531305A/ja active Pending
- 2003-06-05 AU AU2003240746A patent/AU2003240746A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5556847A (en) * | 1994-10-27 | 1996-09-17 | Duquesne University Of The Holy Ghost | Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors |
WO1999052519A2 (fr) * | 1998-04-14 | 1999-10-21 | The General Hospital Corporation | Methodes de traitement de troubles neuropsychiatriques |
WO2000066728A1 (fr) * | 1999-05-03 | 2000-11-09 | Compugen Ltd. | Homologues de star |
WO2001032920A2 (fr) * | 1999-11-03 | 2001-05-10 | Metris Therapeutics Limited | Agents impliques dans l'endometriose |
Non-Patent Citations (4)
Title |
---|
CARON KATHLEEN M ET AL: "Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 94, no. 21, 1997, 1997, pages 11540 - 11545, XP002241664, ISSN: 0027-8424 * |
KALLEN C B ET AL: "UNVEILING THE MECHANISM OF ACTION AND REGULATION OF THE STEROIDOGENIC ACUTE REGULATORY PROTEIN", MOLECULAR AND CELLULAR ENDOCRINOLOGY, AMSTERDAM, NL, vol. 145, no. 1/2, 25 October 1998 (1998-10-25), pages 39 - 45, XP000900751, ISSN: 0303-7207 * |
KIMOTO TETSUYA ET AL: "Neurosteroid synthesis by cytochrome P450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis.", ENDOCRINOLOGY, vol. 142, no. 8, August 2001 (2001-08-01), pages 3578 - 3589, XP002241665, ISSN: 0013-7227 * |
STOCCO DOUGLAS M: "Tracking the role of a StAR in the sky of the new millennium.", MOLECULAR ENDOCRINOLOGY, vol. 15, no. 8, August 2001 (2001-08-01), pages 1245 - 1254, XP002241663, ISSN: 0888-8809 * |
Also Published As
Publication number | Publication date |
---|---|
WO2003104811A2 (fr) | 2003-12-18 |
EP1512013A2 (fr) | 2005-03-09 |
JP2005531305A (ja) | 2005-10-20 |
AU2003240746A1 (en) | 2003-12-22 |
AU2003240746A8 (en) | 2003-12-22 |
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