WO2003043627A1 - New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma - Google Patents
New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma Download PDFInfo
- Publication number
- WO2003043627A1 WO2003043627A1 PCT/IN2001/000203 IN0100203W WO03043627A1 WO 2003043627 A1 WO2003043627 A1 WO 2003043627A1 IN 0100203 W IN0100203 W IN 0100203W WO 03043627 A1 WO03043627 A1 WO 03043627A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- formulation
- unique
- asmakure
- asthma
- powder
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Definitions
- Asmakure is distinctive in its formulation as it covers all mediators acting as broncho-constrictors while other prevalent herbal medicines largely aim at only single mediator called leukotrienes. Asmakure , thus goes to the root of asthmatic disorder and eliminates it in a unique manner. Further.with regular use of Asmakure, patients who are on oral steroid therapy, inhaled steroids and bronchodilators or in extreme cases on inhaled adrenoreceptor agonists etc. , would gradually find themselves weaned away from the use thereof. All these unique features of Asmakure constitute its field of invention as a unique medicine.
- Asthma is an inflammatory disorder of respiratory system with breathing difficulties.
- drugs available in the modern medicines (steroid, ⁇ adrenoreceptor agonist, mast cell stabilizer, brochodilator) to treat asthma. All the modern drugs have restriction of their treatment due to their high toxicity. And none of them are curative medicines for treating asthma. After a prolonged period of extensive research, our group of scientists have ultimately invented one unique anti asthmatic drug which has no side effect. Clinically it has been revealed that this new invention has positive curative value in asthma treatment.
- asthma is defined as a chronic inflammatory disorder of the airways
- a herbal based drug with ingredients which have known properties for expectorant action and promoting expulsion of bronchial secretions. Further aided by ingredients having carminative and astringent properties, Asmakure has ability to offer complete curative treatment for people suffering not only from Asthma but also builds up complete and full immunity against comman cough and cold.
- Raw materials were procured from authentic sources.
- Phytochemical tests for checking the raw materials Chemical tests for carbohydrates , tannins , alkaloids , anthraquinones , fixed oils and fats , volatile oils and resins , were performed. Morphological and anatomical studies were carried out with the different parts of the material. For powdered drugs, microscopical examinations were done. Thus through the phytochemical tests , quality of the herb materials was authenticated.
- Fresh leaves of the plant Adhatoda Vasica were collected in the month of Oct-nov.
- the leaves were washed with double distilled water (with preservative to check any microbial contamination) and dried leaves were grinded in a pulverizer and passed through the mesh # 100.
- the grinded leaves powder were then extracted in a soxhlet extractor with water and alcohol at pH 6.5.
- the extracted materials were then dried in a spray drier.
- the specification of the leaf extract is as follows:
- the sieved nine powdered herb materials (e.g. talishpatra, ada, golmorich, Bara-elaichi, dachini, Pipul , nisadal, etc.) were separately weighed and mixed thoroughly in a Double Cone Mixture (National Engg. Make) for 15 minutes (20-24 rotation/min). Properly mixed material was then collected in a closed container to avoid catching of moisture from the environment. Bulk density of the material was calculated (0.451 gm/cc) following the standard methods. The room temperature was maintained at 24 ⁇ 1° C before filling.
- the powdered mixture was then filled into bottles by semi-automatic powder filling machine.
- the filled bottles were transferred to a bottle sealing machine. After sealing , they were transferred to an automatic Capping machine and labeling machine.
- QC Testing The sample was taken at random from the sealed bottles for QC testing like phytochemical test, pharmaceuticakl test (water content, etc).
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2001/000203 WO2003043627A1 (en) | 2001-11-19 | 2001-11-19 | New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
CA002503669A CA2503669A1 (en) | 2001-11-19 | 2001-11-19 | New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
AU2002214251A AU2002214251A1 (en) | 2001-11-19 | 2001-11-19 | New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2001/000203 WO2003043627A1 (en) | 2001-11-19 | 2001-11-19 | New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003043627A1 true WO2003043627A1 (en) | 2003-05-30 |
WO2003043627A8 WO2003043627A8 (en) | 2006-08-24 |
Family
ID=11076410
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2001/000203 WO2003043627A1 (en) | 2001-11-19 | 2001-11-19 | New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2002214251A1 (en) |
CA (1) | CA2503669A1 (en) |
WO (1) | WO2003043627A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007104985A1 (en) * | 2006-03-16 | 2007-09-20 | Nicholas John Larkins | Compositions comprising apocynin , ginkgo and ginger and uses thereo |
CN104474506A (en) * | 2014-11-29 | 2015-04-01 | 黄根强 | Traditional Chinese medicine composition for treating cough variant asthma |
CN105012817A (en) * | 2015-08-05 | 2015-11-04 | 陈瑜 | Traditional Chinese medicine formula for relieving cough, relieving asthma and eliminating phlegm and preparing method thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107095993A (en) * | 2017-06-19 | 2017-08-29 | 马绪梅 | A kind of Chinese medicine for treating Respiratory Medicine bronchopulmonary aspergillosis |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10113328A1 (en) * | 2000-03-28 | 2001-11-15 | Dabur Res Foundation Sahibabad | New herbal composition for treating gynecological and other related disorders comprises solvent extracted herbal extract and a plant coagulate |
-
2001
- 2001-11-19 AU AU2002214251A patent/AU2002214251A1/en not_active Abandoned
- 2001-11-19 CA CA002503669A patent/CA2503669A1/en not_active Abandoned
- 2001-11-19 WO PCT/IN2001/000203 patent/WO2003043627A1/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10113328A1 (en) * | 2000-03-28 | 2001-11-15 | Dabur Res Foundation Sahibabad | New herbal composition for treating gynecological and other related disorders comprises solvent extracted herbal extract and a plant coagulate |
Non-Patent Citations (5)
Title |
---|
CHATTERJEE S: "BRONCHODILATORY AND ANTI-ALLERGIC EFFECT OF PULMOFLEX - A PROPRIETARY HERBAL FORMULATION", INDIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, ASSOCIATION OF PHYSIOLOGISTS AND PHARMACOLOGISTS, IN, vol. 43, no. 4, October 1999 (1999-10-01), pages 486 - 490, XP008007676, ISSN: 0019-5499 * |
HERBICURE PRIVATE LIMITED: "Asmakure", HERBICURE (HOME PAGE), XP002216128, Retrieved from the Internet <URL:www.herbicureindia.com/Asmakure.asp> [retrieved on 20021009] * |
KOHINOOR MANDAL: "Herbicure rejects US co's offer", BUSINESS LINE, FINANCIAL DAILY FROM THE HINDU GROUP OF PUBLICATIONS, 12 February 2002 (2002-02-12), XP002216127, Retrieved from the Internet <URL:www.blonnet.com/bline/2002/02/12/stories/2002021200670400.htm> [retrieved on 20021009] * |
MATHUR ET AL: "Pulmoflex in Allergic Rhinitis", INDINA JOURNAL OF INDIGENOUS MEDICINES, vol. 17, no. 2, 1996, pages 25 - 29, XP001100058 * |
UNI: "First Indian herbal company makes a debut with drug for asthma", DAILY EXCELSIOR, 11 February 2002 (2002-02-11), XP002216129, Retrieved from the Internet <URL:www.dailyexcelsior.com/02feb11/busi.htmA search with Google revealed that the product is already marketed "Asmakure-TM",> [retrieved on 20021009] * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007104985A1 (en) * | 2006-03-16 | 2007-09-20 | Nicholas John Larkins | Compositions comprising apocynin , ginkgo and ginger and uses thereo |
US8394423B2 (en) | 2006-03-16 | 2013-03-12 | Nicholas John Larkins | Compositions comprising apocynin, ginkgo and ginger and uses thereof |
CN104474506A (en) * | 2014-11-29 | 2015-04-01 | 黄根强 | Traditional Chinese medicine composition for treating cough variant asthma |
CN105012817A (en) * | 2015-08-05 | 2015-11-04 | 陈瑜 | Traditional Chinese medicine formula for relieving cough, relieving asthma and eliminating phlegm and preparing method thereof |
Also Published As
Publication number | Publication date |
---|---|
AU2002214251A1 (en) | 2003-06-10 |
CA2503669A1 (en) | 2003-05-30 |
WO2003043627A8 (en) | 2006-08-24 |
AU2002214251A8 (en) | 2003-06-10 |
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