WO2003040382A1 - Procede de production d'un derive de chromane optiquement actif et d'un produit intermediaire - Google Patents
Procede de production d'un derive de chromane optiquement actif et d'un produit intermediaire Download PDFInfo
- Publication number
- WO2003040382A1 WO2003040382A1 PCT/JP2002/011592 JP0211592W WO03040382A1 WO 2003040382 A1 WO2003040382 A1 WO 2003040382A1 JP 0211592 W JP0211592 W JP 0211592W WO 03040382 A1 WO03040382 A1 WO 03040382A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optically active
- derivative
- producing optically
- active chroman
- chroman derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
- C07C303/28—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/245—Halogenated derivatives monocyclic polyhydroxylic containing halogens bound to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/494,671 US20050014818A1 (en) | 2001-11-09 | 2002-11-07 | Process for producing optically active chroman derivative and intermediate |
JP2003542628A JPWO2003040382A1 (ja) | 2001-11-09 | 2002-11-07 | 光学活性クロマン誘導体の製造法および中間体 |
EP02781744A EP1445324A4 (en) | 2001-11-09 | 2002-11-07 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMAN DERIVATIVE AND INTERMEDIATE PRODUCT |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001-345232 | 2001-11-09 | ||
JP2001345232 | 2001-11-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003040382A1 true WO2003040382A1 (fr) | 2003-05-15 |
Family
ID=19158610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/011592 WO2003040382A1 (fr) | 2001-11-09 | 2002-11-07 | Procede de production d'un derive de chromane optiquement actif et d'un produit intermediaire |
Country Status (4)
Country | Link |
---|---|
US (1) | US20050014818A1 (ja) |
EP (1) | EP1445324A4 (ja) |
JP (1) | JPWO2003040382A1 (ja) |
WO (1) | WO2003040382A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007066755A1 (ja) * | 2005-12-08 | 2007-06-14 | Chisso Corporation | ヒドロクマリン骨格を含有する化合物、液晶組成物、および液晶表示素子 |
JP2016165693A (ja) * | 2015-03-10 | 2016-09-15 | 国立大学法人名古屋大学 | 環化触媒、クロマン類の製法、ピロリジン類の製法及びリン酸ジエステルアミド |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1874756A1 (en) * | 2005-04-22 | 2008-01-09 | Wyeth | Chromane and chromene derivatives and uses thereof |
TW200815388A (en) * | 2006-04-18 | 2008-04-01 | Wyeth Corp | Chromane and chromene derivatives and uses thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1296431A (ja) * | 1970-01-26 | 1972-11-15 | ||
EP0539803A1 (de) * | 1991-10-28 | 1993-05-05 | Bayer Ag | Triazaspirodecanon-Methyl-Chromane zur Bekämpfung von Erkrankungen des Zentralnervensystems |
EP0702010A1 (fr) * | 1994-09-15 | 1996-03-20 | Adir Et Compagnie | Nouveaux dérivés du benzopyrane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
EP0707007A1 (en) * | 1994-10-14 | 1996-04-17 | MERCK PATENT GmbH | Amino(thio)ether derivatives as CNS active agents |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
US5300523A (en) * | 1988-07-28 | 1994-04-05 | Bayer Aktiengesellschaft | Substituted aminomethyltetralins and their heterocyclic analogues |
US5089637A (en) * | 1990-03-21 | 1992-02-18 | Pfizer Inc. | Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde |
DE4140542A1 (de) * | 1991-12-09 | 1993-06-17 | Bayer Ag | Piperdylmethyl substituierte chormanderivate |
DE4140540A1 (de) * | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
DE69616446T2 (de) * | 1995-02-03 | 2002-05-16 | Kaneka Corp., Osaka | Verfahren zur herstellung von alpha-haloketonen, alpha-halohydrinen und epoxiden |
ATE280218T1 (de) * | 1997-02-07 | 2004-11-15 | Kaneka Corp | Neue carbonyl-reduktase, gene welche diese kodieren und methoden zu deren verwendung |
US6133277A (en) * | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
JP2000175693A (ja) * | 1998-12-18 | 2000-06-27 | Kanegafuchi Chem Ind Co Ltd | (r)−2−ヒドロキシ−1−フェノキシプロパン誘導体の製造方法 |
-
2002
- 2002-11-07 WO PCT/JP2002/011592 patent/WO2003040382A1/ja not_active Application Discontinuation
- 2002-11-07 JP JP2003542628A patent/JPWO2003040382A1/ja active Pending
- 2002-11-07 EP EP02781744A patent/EP1445324A4/en not_active Withdrawn
- 2002-11-07 US US10/494,671 patent/US20050014818A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1296431A (ja) * | 1970-01-26 | 1972-11-15 | ||
EP0539803A1 (de) * | 1991-10-28 | 1993-05-05 | Bayer Ag | Triazaspirodecanon-Methyl-Chromane zur Bekämpfung von Erkrankungen des Zentralnervensystems |
EP0702010A1 (fr) * | 1994-09-15 | 1996-03-20 | Adir Et Compagnie | Nouveaux dérivés du benzopyrane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
EP0707007A1 (en) * | 1994-10-14 | 1996-04-17 | MERCK PATENT GmbH | Amino(thio)ether derivatives as CNS active agents |
Non-Patent Citations (3)
Title |
---|
See also references of EP1445324A4 * |
SUDA M. ET AL.: "Dichloromethylenation of esters and lactones by triphenylphosphine-carbon tetrachloride reagent", TETRAHEDRON LETT., vol. 22, no. 8, 1981, pages 759 - 762, XP002961034 * |
YANG D. ET AL.: "Regioselective intramolecular oxidation of phenols and anisoles by dioxiranes generated in situ", J. ORG. CHEM., vol. 65, no. 13, 2000, pages 4179 - 4184, XP002961035 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007066755A1 (ja) * | 2005-12-08 | 2007-06-14 | Chisso Corporation | ヒドロクマリン骨格を含有する化合物、液晶組成物、および液晶表示素子 |
KR101322592B1 (ko) | 2005-12-08 | 2013-10-25 | 제이엔씨 주식회사 | 히드로쿠마린 골격을 함유하는 화합물, 액정 조성물, 및액정 표시 소자 |
JP5332206B2 (ja) * | 2005-12-08 | 2013-11-06 | Jnc株式会社 | ヒドロクマリン骨格を含有する化合物、液晶組成物、および液晶表示素子 |
JP2016165693A (ja) * | 2015-03-10 | 2016-09-15 | 国立大学法人名古屋大学 | 環化触媒、クロマン類の製法、ピロリジン類の製法及びリン酸ジエステルアミド |
Also Published As
Publication number | Publication date |
---|---|
EP1445324A1 (en) | 2004-08-11 |
US20050014818A1 (en) | 2005-01-20 |
EP1445324A4 (en) | 2005-02-16 |
JPWO2003040382A1 (ja) | 2005-03-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0013885A (pt) | Comprimidos aperfeiçoados | |
EP1408041A4 (en) | PROCESS FOR THE PREPARATION OF AMIDINE DERIVATIVES | |
WO1999030548A3 (en) | Method for the preparation of citalopram | |
WO2002055519A3 (en) | Novel process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2r, 4r)-4-hydroxy -6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1h-pyrrole-3-carboxylic acid phenylamide | |
WO2003047531A3 (en) | Preparation of orlistat and orlistat crystalline forms | |
PT872481E (pt) | Derivado de depsipéptido, processo para a sua produção, e novos intermediários do mesmo | |
WO2002055383A3 (en) | Monolithic part and process for making the same | |
WO2001057014A3 (en) | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | |
IL172973A (en) | Process for the preparation of (4s, 5r) - n - boc - 2 - (2' 4 - dimethoxyphenyl) - 4 - isobutyl - 1 - oxazolidine - 5 - carboxylic acid | |
CA2395229A1 (en) | Methods and compositions for the manufacture of ophthalmic lenses | |
WO2002030870A3 (de) | Substituierte c-cyclohexylmethylamin-derivate | |
CA2333192A1 (en) | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2h-pyran-2-one | |
EP1348712A4 (en) | L-NUCLEIC ACID DERIVATIVES AND METHOD FOR THEIR SYNTHESIS | |
WO2003040382A1 (fr) | Procede de production d'un derive de chromane optiquement actif et d'un produit intermediaire | |
WO2003011849A8 (en) | Process for the production of beraprost and its salts | |
EP1076057A4 (en) | FEBRIFUGIN AND ISPOFEBRIFUGIN AND METHOD FOR THE PRODUCTION OF THE BOTH | |
ES2062336T3 (es) | Derivados de benzoxepina. | |
AU2002360928A1 (en) | A method for manufacturing and fractionating gelling and non-gelling carrageenans from bi-component seaweed | |
EP1179298A3 (en) | Pregelatinized starches for improved snack products | |
WO2000064882A3 (en) | Enantiomers of mercapto lactones and processes for their synthesis | |
NO20052329L (no) | Fremgangsmate for rensingen av 1,4-butandiol-mononitrat | |
EP1052258A4 (en) | PROCESS FOR PRODUCING BETA-HYDROXY-GAMMA-BUTYROLACTONE DERIVATIVES AND BETA- (METH) ACRYLOYLOXY-GAMMA-BUTYROLACTONE DERIVATIVES | |
EP1367050A4 (en) | 2-METHYLINDOLE-4-ACETIC ACID, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING INTERMEDIATE PRODUCT THEREOF | |
WO2000076966A3 (de) | Indolinylamidderivate und deren verwendung als antivirale arzneimittel | |
WO2001007439A3 (en) | Process for the production of epothiolone b and derivatives as well as intermediate products for this process |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): JP US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): CH DE FR GB |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2003542628 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 10494671 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002781744 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2002781744 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 2002781744 Country of ref document: EP |