WO2003004663A3 - Process for the preparation of l-amino acids using strains of the enterobacteriaceae family - Google Patents

Process for the preparation of l-amino acids using strains of the enterobacteriaceae family Download PDF

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Publication number
WO2003004663A3
WO2003004663A3 PCT/EP2002/006560 EP0206560W WO03004663A3 WO 2003004663 A3 WO2003004663 A3 WO 2003004663A3 EP 0206560 W EP0206560 W EP 0206560W WO 03004663 A3 WO03004663 A3 WO 03004663A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
amino acids
strains
enterobacteriaceae family
enterobacteriaceae
Prior art date
Application number
PCT/EP2002/006560
Other languages
French (fr)
Other versions
WO2003004663A2 (en
Inventor
Mechthild Rieping
Original Assignee
Degussa
Mechthild Rieping
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10132946A external-priority patent/DE10132946A1/en
Application filed by Degussa, Mechthild Rieping filed Critical Degussa
Priority to EP02730294A priority Critical patent/EP1404821B1/en
Priority to AT02730294T priority patent/ATE449167T1/en
Priority to AU2002302642A priority patent/AU2002302642A1/en
Priority to DK02730294.2T priority patent/DK1404821T3/en
Priority to DE60234444T priority patent/DE60234444D1/en
Priority to US10/481,746 priority patent/US7172883B2/en
Publication of WO2003004663A2 publication Critical patent/WO2003004663A2/en
Publication of WO2003004663A3 publication Critical patent/WO2003004663A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to a process for the preparation of L-amino acids, in particular L-threonine.
PCT/EP2002/006560 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family WO2003004663A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP02730294A EP1404821B1 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
AT02730294T ATE449167T1 (en) 2001-07-06 2002-06-14 METHOD FOR PRODUCING L-AMINO ACIDS USING STRAINS OF THE ENTEROBACTERIACEAE FAMILY
AU2002302642A AU2002302642A1 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
DK02730294.2T DK1404821T3 (en) 2001-07-06 2002-06-14 Process for Preparation of L-Amino Acids in the Derivation of Strains of the Enterobacteriaceae Family
DE60234444T DE60234444D1 (en) 2001-07-06 2002-06-14 PROCESS FOR THE PREPARATION OF L-AMINO ACIDS WITH COMPOUNDS OF THE FAMILY ENTEROBACTERIACEAE
US10/481,746 US7172883B2 (en) 2001-07-06 2002-06-14 Process for L-amino acid production using Enterobacteriaceae by enhancing ahpC or ahpF encoding alkyl hydroperoxide reductase

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10132946.6 2001-07-06
DE10132946A DE10132946A1 (en) 2001-07-06 2001-07-06 Fermentative production of L-amino acids useful in e.g. animal nutrition, comprising growing Enterobacteriaceae in which activity of at least one specific gene is increased
US30379001P 2001-07-10 2001-07-10
US60/303,790 2001-07-10

Publications (2)

Publication Number Publication Date
WO2003004663A2 WO2003004663A2 (en) 2003-01-16
WO2003004663A3 true WO2003004663A3 (en) 2003-07-24

Family

ID=26009659

Family Applications (9)

Application Number Title Priority Date Filing Date
PCT/EP2002/006564 WO2003004664A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced fba expression
PCT/EP2002/006567 WO2003004671A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006563 WO2003004670A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced pts-g expression
PCT/EP2002/006568 WO2003004675A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006562 WO2003004674A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006566 WO2003004665A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006561 WO2003004669A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced mop-b expression
PCT/EP2002/006565 WO2003004598A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006560 WO2003004663A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family

Family Applications Before (8)

Application Number Title Priority Date Filing Date
PCT/EP2002/006564 WO2003004664A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced fba expression
PCT/EP2002/006567 WO2003004671A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006563 WO2003004670A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced pts-g expression
PCT/EP2002/006568 WO2003004675A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006562 WO2003004674A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006566 WO2003004665A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
PCT/EP2002/006561 WO2003004669A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced mop-b expression
PCT/EP2002/006565 WO2003004598A2 (en) 2001-07-06 2002-06-14 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family

Country Status (9)

Country Link
US (4) US20040241813A1 (en)
EP (9) EP1404836B1 (en)
AT (8) ATE462790T1 (en)
AU (8) AU2002316984A1 (en)
CA (1) CA2453008C (en)
DE (7) DE60235810D1 (en)
DK (2) DK1404838T3 (en)
ES (4) ES2262815T3 (en)
WO (9) WO2003004664A2 (en)

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US20030054503A1 (en) * 2001-04-03 2003-03-20 Degussa Ag Process for the production of L-amino acids using strains of the family enterobacteriaceae that contain an attenuated dgsA gene
US20040241813A1 (en) * 2001-07-06 2004-12-02 Mechthild Rieping Procsess for the preration of l-amino acids using strains of the enterobacteriaceae family
DE10132945A1 (en) * 2001-07-06 2003-01-16 Degussa Process for the fermentative production of L-amino acids using strains of the Enterobacteriaceae family
DE10303571A1 (en) 2003-01-30 2004-08-12 Degussa Ag Process for the fermentative production of L-amino acids using strains of the Enterobacteriaceae family
DE10316109A1 (en) 2003-04-09 2004-10-21 Degussa Ag Process for the fermentative production of L-amino acids using strains of the family Enterobacteriaceae
DE102004005836A1 (en) 2004-02-06 2005-09-15 Degussa Ag Process for the preparation of L-amino acids using strains of the family Enterobacteriaceae
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DE102004037572A1 (en) 2004-08-03 2006-02-23 Degussa Ag Process for the preparation of L-amino acids using strains of the family Enterobacteriaceae
DE102005018835A1 (en) 2005-04-22 2006-11-02 Degussa Ag Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
US8187842B2 (en) * 2005-06-20 2012-05-29 Archer Daniels Midland Company Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals
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EP1929029A1 (en) * 2005-09-27 2008-06-11 Ajinomoto Co., Inc. An l-amino acid-producing bacterium and a method for producing l-amino acids
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DE102007051024A1 (en) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Process for the preparation of L-amino acids using strains of the family Enterobacteriaceae
JP2010130899A (en) 2007-03-14 2010-06-17 Ajinomoto Co Inc Microorganism producing l-glutamic acid-based amino acid, and method for producing amino acid
EP1975241A1 (en) 2007-03-29 2008-10-01 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family
DE102007044134A1 (en) 2007-09-15 2009-03-19 Evonik Degussa Gmbh Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
DE102007052270A1 (en) 2007-11-02 2009-05-07 Evonik Degussa Gmbh Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
EP2060636A1 (en) 2007-11-14 2009-05-20 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family
EP2098597A1 (en) 2008-03-04 2009-09-09 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family
DE102008002309A1 (en) 2008-06-09 2009-12-10 Evonik Degussa Gmbh Process for the preparation of L-amino acids using improved strains of the family Enterobacteriaceae
DE102008044768A1 (en) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Process for the preparation of organochemical compounds using improved strains of the family Enterobacteriaceae
EP2267145A1 (en) 2009-06-24 2010-12-29 Evonik Degussa GmbH Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family
EP2674499B1 (en) 2011-02-09 2020-04-01 Kyowa Hakko Bio Co., Ltd. Method for producing target substance by fermentation process
AR086790A1 (en) * 2011-06-29 2014-01-22 Metabolic Explorer Sa A MICROORGANISM FOR THE PRODUCTION OF METIONIN WITH IMPORTATION OF IMPROVED GLUCOSE
CN104411821B (en) * 2012-06-18 2017-08-08 代谢探索者公司 Recombinant microorganism for fermenting and producing methionine
PE20150681A1 (en) 2013-05-13 2015-05-15 Ajinomoto Kk METHOD TO PRODUCE L-AMINO ACIDS
JP2016165225A (en) 2013-07-09 2016-09-15 味の素株式会社 Method for producing useful substance
JP6459962B2 (en) 2013-10-21 2019-01-30 味の素株式会社 Method for producing L-amino acid
JP6519476B2 (en) 2013-10-23 2019-05-29 味の素株式会社 Production method of target substance
JP6623690B2 (en) 2015-10-30 2019-12-25 味の素株式会社 Method for producing glutamic acid-based L-amino acid
JP2017192325A (en) * 2016-04-19 2017-10-26 三菱ケミカル株式会社 Method for producing organic acid
JP7066977B2 (en) 2017-04-03 2022-05-16 味の素株式会社 Manufacturing method of L-amino acid
US11053526B2 (en) 2018-08-09 2021-07-06 Evonik Operations Gmbh Process for preparing L amino acids using improved strains of the enterobacteriaceae family
EP3608409A1 (en) 2018-08-09 2020-02-12 Evonik Operations GmbH Process for preparing l amino acids using improved strains of the enterobacteriaceae family
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
JPWO2022092018A1 (en) 2020-10-28 2022-05-05
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid

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US5807735A (en) * 1995-03-29 1998-09-15 Exxon Research And Engineering Company Solvent-resistant microorganisms
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Also Published As

Publication number Publication date
WO2003004598A2 (en) 2003-01-16
ATE383436T1 (en) 2008-01-15
WO2003004663A2 (en) 2003-01-16
ATE334220T1 (en) 2006-08-15
ES2336655T3 (en) 2010-04-15
DK1404838T3 (en) 2010-07-12
ATE415478T1 (en) 2008-12-15
US20040241813A1 (en) 2004-12-02
WO2003004674A3 (en) 2003-08-28
WO2003004664A3 (en) 2003-07-31
DE60228961D1 (en) 2008-10-30
US7241600B2 (en) 2007-07-10
WO2003004671A2 (en) 2003-01-16
EP1404836A2 (en) 2004-04-07
EP1404857A2 (en) 2004-04-07
WO2003004664A2 (en) 2003-01-16
EP1404838B1 (en) 2010-03-31
WO2003004675A2 (en) 2003-01-16
WO2003004675A3 (en) 2003-09-18
EP1404838A2 (en) 2004-04-07
WO2003004665A3 (en) 2003-08-21
AU2002314168A1 (en) 2003-01-21
EP1404821B1 (en) 2009-11-18
EP1404839A2 (en) 2004-04-07
DK1404821T3 (en) 2010-03-22
AU2002319229A1 (en) 2003-01-21
DE60230274D1 (en) 2009-01-22
EP1404835B1 (en) 2008-09-17
ATE323778T1 (en) 2006-05-15
US20050069993A1 (en) 2005-03-31
EP1404858A2 (en) 2004-04-07
CA2453008C (en) 2011-03-22
AU2002316983A1 (en) 2003-01-21
DE60224536T2 (en) 2009-01-08
WO2003004674A2 (en) 2003-01-16
WO2003004665A2 (en) 2003-01-16
AU2002316982A1 (en) 2003-01-21
ATE408691T1 (en) 2008-10-15
EP1404836B1 (en) 2008-11-26
EP1404837A2 (en) 2004-04-07
CA2453008A1 (en) 2003-01-16
WO2003004671A3 (en) 2003-09-18
EP1404837B1 (en) 2008-12-10
AU2002316984A1 (en) 2003-01-21
ATE417107T1 (en) 2008-12-15
DE60234444D1 (en) 2009-12-31
EP1404821A2 (en) 2004-04-07
US7172883B2 (en) 2007-02-06
US20050106687A1 (en) 2005-05-19
ATE462790T1 (en) 2010-04-15
WO2003004670A3 (en) 2003-07-31
ES2262815T3 (en) 2006-12-01
DE60230040D1 (en) 2009-01-08
WO2003004669A2 (en) 2003-01-16
ES2318022T3 (en) 2009-05-01
EP1404856A2 (en) 2004-04-07
DE60210772T2 (en) 2007-04-12
DE60210772D1 (en) 2006-05-24
DE60235810D1 (en) 2010-05-12
ATE449167T1 (en) 2009-12-15
EP1404856B1 (en) 2006-07-26
WO2003004669A3 (en) 2003-07-24
WO2003004670A2 (en) 2003-01-16
US20050054066A1 (en) 2005-03-10
ES2343944T3 (en) 2010-08-13
EP1404857B1 (en) 2006-04-19
AU2002345038A1 (en) 2003-01-21
DE60224536D1 (en) 2008-02-21
AU2002302642A1 (en) 2003-01-21
WO2003004598A3 (en) 2003-12-18
EP1404858B1 (en) 2008-01-09
AU2002314169A1 (en) 2003-01-21
EP1404835A2 (en) 2004-04-07

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