WO2003002072A1

WO2003002072A1 - Compositions containing a hydroxydiphenyl ether derivative inhibiting body odours

Info

Publication number: WO2003002072A1
Application number: PCT/FR2002/001788
Authority: WO
Inventors: Serge Forestier; Christophe Courbiere
Original assignee: L'oréal
Priority date: 2001-06-29
Filing date: 2002-05-28
Publication date: 2003-01-09
Also published as: FR2826572A1; FR2826572B1

Abstract

The invention concerns an aerosol device consisting of a container comprising a aerosol composition consisting of a liquid phase (a) (or liquor) comprising at least a hydroxydiphenyl ether derivative and (b) at least a particular propellant and of means for dispensing said aerosol composition as well as the method for treating human body odours and in particular axillary odours with said device.

Description

COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODORS

The present invention relates to an aerosol device consisting of a container comprising an aerosol composition consisting, on the one hand, of a liquid phase (a) (or juice) comprising at least one derivative of hydroxydiphenyl ether and (b) of at least at least one particular propellant and by a means of distributing said aerosol composition as well as to the process for treating human body odors and in particular axillary using this device.

In the cosmetic field, it is well known to use, in topical application, deodorant products containing active substances, of antiperspirant type or of bactericidal type, to reduce, even eliminate, generally unpleasant axillary odors.

Antiperspirants have the effect of limiting sweat flow. They generally consist of aluminum salts which, on the one hand, are irritating to the skin and which, on the other hand, reduce the sweat flow by modifying the cutaneous physiology, which is not satisfactory.

Bactericidal substances inhibit the development of the skin flora responsible for axillary odors.

Among the bactericidal products, the most commonly used is Triclosan (2,4,4'-trichloro-2'-hydroxydiphenylether).

In order to obtain long-term efficacy, we are looking for new products with deodorant action, that is to say products which are capable of modifying, reducing and / or removing or preventing development. body odor (this definition is given in the book “Cosmetic Science and Technology Series” - 1988 / Volume 7 chap.10 - lllc). In patent application EP1053989, use has been made in cosmetics of derivatives of hydroxydiphenyl ethers as antimicrobial active agents in particular for deodorizing the skin, mucous membranes, hair, various materials such as paper, paint. These derivatives can be used in different galenical forms such as solutions, lotions, emulsions which can be delivered, for example, in the form of spray compositions. The presentation in the form of an aerosol device pressurized with a propellant is particularly appreciated by consumers. The nature of the propellant plays a crucial role in the stability of the composition and the quality of the spray and therefore in the effectiveness of the product.

After numerous researches carried out on the question, the Applicant has now discovered, unexpectedly and surprisingly, that aerosol devices associating compositions containing derivatives of hydroxydiphenyl ethers with particular propellants had the property of preventing the development of odors. body sweat, without the drawbacks of using other propellants.

This discovery is the basis of the present invention.

The present invention thus firstly relates to an aerosol device consisting of a container comprising an aerosol composition and a means of dispensing said aerosol composition, the latter comprising a liquid phase (or juice) containing: a) at least one derivative of 'hydroxydiphenyl ethers of formula (1):

wherein R1, R2, R3 and R4, identical or different, denote Z, OZ, COZ, -COOZ, CONZZ ', C ₆ -C ₃ o aralkyl or C ₇ -C ₄₀ alkylaryl or C ₇ -C ₄₀ optionally substituted by one or more groups chosen from OH,

NH ₂ , halogen, carboxy, or C1-C30 carbonyl alkoxy;

Z and Z ', identical or different, denote H, a linear or branched Cι-C ₃₀ hydrocarbon radical, cyclic or acyclic, saturated or unsaturated, interrupted or not by one or more heteroatoms or carbonyl groups, substituted or not by one or more groups chosen from OH, NH ₂ , halogen, carboxy or alkoxy

C-ι-C ₃₀ carbonyl; b) at least one propellant selected from dimethyl ether, linear or branched alkanes containing from 2 to 6 carbon atoms or their mixtures.

Among the compounds of formula (1) which can be used according to the present invention, preference is given to:

- 2,4'-dihydroxy diphenyl ether

- 2-hydroxy 2'-ethyl diphenyl ether

- 2-hydroxy 2'-isopropyl diphenyl ether

- 2-hydroxy 2'-methyl diphenyl ether

- 2-hydroxy 2'-sec.butyl diphenyl ether

- 2-hydroxy 2'-tert.butyl diphenyl ether

- 2-hydroxy 3-butanoyl diphenyl ether

- 2-hydroxy 3-propanoyl diphenyl ether

- 2-hydroxy 4-formyl diphenyl ether

- 2-hydroxy 4'-methyl 5-formyl diphenyl ether

- 2-hydroxy 5-butanoyl diphenyl ether

- 2-hydroxy 5-formyl diphenyl ether

- 2-hydroxy diphenyl ether

- 3-hydroxy 2'-methyl diphenyl ether

- 3-hydroxy 2'-sec.butyl diphenyl ether

- 3-hydroxy 2'-methyl 4-n-propyl diphenyl ether

- 3-hydroxy 3'-methyl diphenyl ether

- 3-hydroxy 3'-methyl 4-n-propyl diphenyl ether

- 3-hydroxy 4- (1-hydroxy 2-methylpropyl) diphenyl ether

- 3-hydroxy 4-butanoyl diphenyl ether - 3-hydroxy 4-butyl diphenyl ether

- 3-hydroxy 4-dimethylpropyl diphenyl ether

- 3-hydroxy 4-dimethylpropyl 3'-methyl diphenyl ether

- 3-hydroxy 4-hexyl diphenyl ether

- 3-hydroxy 4-hexanoyl diphenyl ether

- 3-hydroxy 4-dodecyl diphenyl ether

- 3-hydroxy 4-isobutanoyl diphenyl ether

- 3-hydroxy 4-isobutyl diphenyl ether

- 3-hydroxy 4-isopentanoyl diphenyl ether

- 3-hydroxy 4-isopropyl diphenyl ether

- 3-hydroxy 4'-isopropyl diphenyl ether

- 3-hydroxy 4-n-butyl diphenyl ether

- 3-hydroxy 4-n-pentyl diphenyl ether

- 3-hydroxy 4-n-propyl diphenyl ether

- 3-hydroxy 4-pentanoyl diphenyl ether

- 3-hydroxy 4-pentyl diphenyl ether

- 3-hydroxy 4-phenylethyl diphenyl ether

- 3-hydroxy 2'-methyl 4-phenylethyl diphenyl ether.

- 3-hydroxy 3'-methyl 4-phenylethyl diphenyl ether

- 3-hydroxy 4-propanoyl diphenyl ether

- 3-hydroxy diphenyl ether

- 3,4'-dihydroxy diphenyl ether

- 4,4'-dihydroxy diphenyl ether

- 4-hydroxy 2'-methyl 5'-isopropyl diphenyl ether

- Lé 4-hydroxy 2'- tert.butyl 5'-methyl diphenyl ether

- 4-hydroxy 2 ', 5'-dimethyl diphenyl ether

- 4-hydroxy 2'-cyclohexyl 5'-methyl diphenyl ether

- 4-hydroxy 2'-isopropyl 4'-ethyl diphenyl ether

- 4-hydroxy 2'-isopropyl 4'-propyl diphenyl ether

- 4-hydroxy 2'-isopropyl 5'-methyl diphenyl ether

- 4-hydroxy 2'-isopropyl diphenyl ether

- 4-hydroxy 2'-isopropyl 4'-phenylethyl diphenyl ether - 4-hydroxy 3- (3-methylbutyl) 4 '- (3-methylbutyl) diphenyl ether

- 4-hydroxy 4'-dimethylpropyl diphenyl ether

- 4-hydroxy 4'-ethyl diphenyl ether

- 4-hydroxy 4'-nonyl diphenyl ether

- 4-hydroxy 4'-phenylethyl diphenyl ether

- 4-hydroxy 4'-propyl diphenyl ether

- 4-hydroxy 4'-trifluoromethyl diphenyl ether

- 4-hydroxy 4'-propanoyl diphenyl ether

- 4-hydroxy diphenyl ether

Even more preferably, 4,4'-dihydroxydiphenyl ether will be used.

In the compositions a) of the invention, the concentration of compound (s) of formula (1) preferably varies from 0.001 to 20%, more preferably from 0.01 to 15% and even more preferably from 0.1 to 10% by weight per relative to the total weight of the composition.

The propellant is chosen from dimethyl ether, volatile hydrocarbons such as n-butane, propane, isobutane and their mixtures.

The composition containing the compound (s) of formula (1) and the propellant (s) may be in the same compartment or in different compartments in the aerosol container.

According to the invention, the concentration of propellant (s) generally varies from 5 to 90% by weight pressurized and more preferably from 15 to 70% by weight relative to the total weight of the pressurized composition.

In addition to the hydroxydiphenyl ether derivatives of formula (1), the composition according to the invention may also contain deodorant active agents or antiperspirant active agents.

Among the deodorant active agents according to the invention, there may be mentioned for example, zinc pyrrolidone carboxylate (more commonly called zinc pidolate), zinc sulfate, zinc chloride, zinc lactate, zinc gluconate and zinc phenoisulfonate, 2,4,4'-trichloro-2'-hydroxydiphenylether (Triclosan), 2,4-dichloro-2 '-hydroxydiphenylether, 3', 4 ', 5'-trichlorosalicylanilide, 1- (3', 4'- dichlorophenyl) -3- (4'-chlorophenyl) urea (triclocarban) or 3,7,11-trimethyldodeca -2,5,10-trienol (Famesol).

Among the antiperspirant active agents there may be mentioned for example aluminum hydrochloride, aluminum chlorohydrex, aluminum chlorohydrex PEG, aluminum chlorohydrex PG, aluminum dichlorohydrate, aluminum dichlorohydrex PEG, aluminum dichlorohydrex PG, l aluminum sesquichlorohydrate, aluminum sesquichlorohydrex PEG, aluminum sesquichlorohydrex PG, aluminum sulfate, aluminum zirconium octachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium trichlorohydrate, metal complexes ( such as aluminum or zirconium) with an amino acid and as described in US Pat. No. 3,792,068. Such complexes are generally known by the name ZAG. ZAG complexes usually have an Al / Zr quotient ranging from approximately 1.67 to 12.5 and a Metal / Cl quotient ranging from approximately 0.73 to 1.93.

The preferred amino acid for preparing such ZAG complexes is glycine. Among these products, mention may be made of aluminum zirconium octachlorohydrex GLY, aluminum zirconium pentachlorohydrex GLY, aluminum zirconium tetrachlorohydrate GLY and aluminum zirconium trichlorohydrate-GLY.

These deodorant or antiperspirant active agents may be present in the composition according to the invention in an amount of approximately 0.001 to 20% by weight relative to the total composition, and preferably in an amount of approximately 0.1 to 10% by weight.

The cosmetic composition according to the invention is conventionally formulated according to the form of presentation for which it is intended.

It is more particularly formulated in a cosmetically acceptable vehicle which may in particular be essentially aqueous, or contain organic solvents and in particular CrC monoalcohols, preferably of ethanol to accelerate the evaporation of the product, or propylene glycol, dipropylene glycol or their ethers.

The cosmetic composition according to the invention can also be formulated as a water-in-oil, oil-in-water emulsion, or as a triple water-in-oil-in-water emulsion (such emulsions are known and described for example by C. FOX in "Cosmetics and Toiletries" - November 1986 - Vol 101 - pages 101-112).

The cosmetic composition according to the invention can also comprise cosmetic adjuvants chosen from fatty substances, gelling agents, emollients, softeners, antioxidants, opacifiers, stabilizers, anti-foaming agents, moisturizing agents, vitamins, perfumes, preservatives, surfactants, fillers, sequestrants, polymers, basifying or acidifying agents, perfumes, dyes, pigments, thickening agents, or any other ingredient usually used in cosmetics for this type of application .

Of course, the person skilled in the art will take care to choose this or these optional additional compounds in such a way that the advantageous properties intrinsically attached to the cosmetic composition in accordance with the invention are not, or not substantially, altered by the addition (s) envisaged. .

The surfactants are preferably chosen from anionic, amphoteric or nonionic surfactants.

The fatty substances can consist of an oil or a wax or a mixture thereof, petrolatum, paraffin, lanolin, hydrogenated lanolin, acetylated lanolin; they also include fatty acids, fatty alcohols such as lauric, cetyl, myristic, stearic, palmitic, oleic alcohol as well as 2-octyldodecanol, fatty acid esters such as glycerol monostearate, polyethylene glycol monostearate , isopropyl myristate, isoprppyl adipate, isopropyl palmitate, octyl palmitate, C12-C15 fatty alcohol benzoates (Finsolv TN from FINETEX), myristic alcohol polyoxypropylenated to 3 moles of propylene oxide (WITCONOL APM from WITCO), triglycerides of fatty acids in Cρ-C-js such as caprylic / capric acid triglycerides.

The oils are chosen from animal, vegetable, mineral or synthetic oils and in particular hydrogenated palm oil, hydrogenated castor oil, petroleum jelly oil, paraffin oil, purcellin oil (octanoate stearyl), silicone oils and isoparaffins.

The waxes are chosen from animal, fossil, vegetable, mineral or synthetic waxes. Mention may in particular bees beeswaxes, Camauba, Candellila, sugar cane, Japanese waxes, ozokerites, Montan wax, microcrystalline waxes, paraffins, waxes and silicone resins.

The thickeners, preferably nonionic, can be chosen from guar gums and modified or unmodified celluloses such as hydroxypropylated guar gum, cetylhydroxyethylcellulose, silicas such as, for example, Bentone Gel MiO sold by the company NL INDUSTRIES or Veegum Ultra, sold by the company POLYPLASTIC.

The cosmetic composition can comprise emollients, which contribute to a soft, dry feeling, non-sticky when the composition is applied to the skin. These emollients can be chosen from products of the volatile silicone type, non-volatile silicones and other non-volatile emollients.

Volatile silicones are defined in a known manner as volatile compounds at room temperature. Among these compounds, mention may be made of cyclic and linear volatile silicones of the dimethylsiloxane type, the chains of which comprise from 3 to 9 silicone residues. Preferably, cyclomethicones D4 or D5 are chosen.

Non-volatile silicones are defined in a known manner as compounds with low vapor pressure at room temperature. Among these compounds are included: polyalkylsiloxanes, in particular linear polyalkylsiloxanes such as, for example, the linear polydimethylsiloxanes, or dimethicones, sold by the company Dow Corning under the name of "Dow Corning 200 Fluid"; polyalkylarylsiloxanes such as, for example, polymethylphenylsiloxanes, sold by the company Dow Corning under the name of “Dow Corning 556 Fluid”; polyether and siloxane copolymers, such as, for example, dimethicone copolyols.

Among the nonvolatile emollients useful in the present invention include for example: hydrocarbon-based derivatives, mineral oils, fatty alcohols, alcohol esters of C ₃ -Cι ₈ with acids C ₃ -Cι ₈ , the esters of benzoic acid with alcohols in Cι ₂ -Cι ₈ and their mixtures, polyols in C ₂ -C ₆ preferably chosen from glycerol, propylene glycol or sorbitol, polymers of polalkylene glycol.

The amounts of these various constituents which may be present in the cosmetic composition according to the invention are those conventionally used for the forms of presentation considered.

The cosmetic composition according to the invention can thus be in the form of a lotion, cream or fluid gel distributed in aerosol spray, and in this regard contain the ingredients generally used in this type of product and well known to those skilled in the art. 'art.

The dispensing means, which forms part of the aerosol device, generally consists of a dispensing valve controlled by a dispensing head, itself comprising a nozzle by which the aerosol composition is vaporized.

The container containing the pressurized composition can be opaque or transparent.

It can be made of glass, polymeric material or metal, possibly covered with a layer of protective varnish. A concrete, but in no way limiting, example illustrating the invention will now be given.

The following aerosol device is produced in accordance with the invention by introducing the following juice and the propellants into an aerosol container provided with conventional dispensing means.

Juice

4,4'-dihydroxy diphenyl ether 2.0g

Ethanol qs 100.0 g

Pressurization scheme

Juice 37%

Dimethyl ether 43%

Pentane 20%

Claims

1. Aerosol device consisting of a container comprising an aerosol composition and a means of dispensing said aerosol composition, the latter comprising a liquid phase (or juice) containing: a) at least one hydroxydiphenyl ether derivative of formula (1 ):

in which R1, R2, R3 and R4, identical or different, denote Z, OZ, COZ, COOZ, CONZZ ', C ₆ -C ₃ yle aryl or C7-C40 aralkyl or C ₇ -C ₄₀ alkylaryl optionally substituted by one or more groups chosen from OH, NH ₂ , halogen, carboxy, or C1-C30 carbonyl alkoxy; Z and Z ', identical or different, denote H, a linear or branched C ₁ -C ₃₀ hydrocarbon radical, cyclic or acyclic, saturated or unsaturated, interrupted or not by one or more heteroatoms or carbonyl groups, substituted or not by one or more groups chosen from OH, NH ₂ , halogen, carboxy or alkoxy C1-C30 carbonyl; b) at least one propellant selected from dimethyl ether, linear or branched alkanes containing from 2 to 6 carbon atoms or their mixtures.

2. Device according to claim 1, characterized in that the compound of formula (1) is chosen from the following compounds:

2,4'-dihydroxy diphenyl ether

2-hydroxy 2'-ethyl diphenyl ether

2-hydroxy 2'-isopropyl diphenyl ether

2-hydroxy 2'-methyl diphenyl ether - 2-hydroxy 2'-sec.butyl diphenyl ether

2-hydroxy 2'-tert.butyl diphenyl ether

2-hydroxy 3-butanoyl diphenyl ether

2-hydroxy 3-propanoyl diphenyl ether 2-hydroxy 4-formyl diphenyl ether

2-hydroxy 4'-methyl 5-formyl diphenyl ether

2-hydroxy 5-butanoyl diphenyl ether

2-hydroxy 5-formyl diphenyl ether

2-hydroxy diphenyl ether

3-hydroxy 2'-methyl diphenyl ether

3-hydroxy 2'-sec.butyl diphenyl ether

3-hydroxy 2'-methyl 4-n-propyl diphenyl ether

3-hydroxy 3'-methyl diphenyl ether

3-hydroxy 3'-methyl 4-n-propyl diphenyl ether

3-hydroxy 4- (1-hydroxy 2-methylpropyl) diphenyl ether

3-hydroxy 4-butanoyl diphenyl ether

3-hydroxy 4-butyl diphenyl ether

3-hydroxy 4-dimethylpropyl diphenyl ether

3-hydroxy 4-dimethylpropyl 3'-methyl diphenyl ether

3-hydroxy 4-hexyl diphenyl ether

3-hydroxy 4-hexanoyl diphenyl ether

3-hydroxy 4-dodecyl diphenyl ether

3-hydroxy 4-isobutanoyl diphenyl ether

3-hydroxy 4-isobutyl diphenyl ether

3-hydroxy 4-isopentanoyl diphenyl ether

3-hydroxy 4-isopropyl diphenyl ether

3-hydroxy 4'-isopropyl diphenyl ether

3-hydroxy 4-n-butyl diphenyl ether

3τhydroxy 4-n-butyl diphenyl ether

3-hydroxy 4-n-pentyl diphenyl ether

3-hydroxy 4-n-propyl diphenyl ether

3-hydroxy 4-pentanoyl diphenyl ether

3-hydroxy 4-pentyl diphenyl ether

3-hydroxy 4-phenylethyl diphenyl ether

3-hydroxy 2'-methyl 4-phenylethyl diphenyl ether

3-hydroxy 3'-methyl 4-phenylethyl diphenyl ether

3-hydroxy 4-propanoyl diphenyl ether 3-hydroxy diphenyl ether

3,4'-dihydroxy diphenyl ether

4,4'-dihydroxy diphenyl ether

4-hydroxy 2'-methyl 5'-isopropyl diphenyl ether

4-hydroxy 2'-tert.butyl 5'-methyl diphenyl ether

4-hydroxy 2 ', 5'-dimethyl diphenyl ether

4-hydroxy 2'-cyclohexyl 5'-methyl diphenyl ether

4-hydroxy 2'-isopropyl 4'-ethyl diphenyl ether

4-hydroxy 2'-isopropyl 4'-propyl diphenyl ether

4-hydroxy 2'-isopropyl 5'-methyl diphenyl ether

4-hydroxy 2'-isopropyl diphenyl ether

4-hydroxy 2'-isopropyl 4'-phenylethyl diphenyl ether

4-hydroxy 3- (3-methylbutyl) 4 '- (3-methylbutyl) diphenyl ether

4-hydroxy 4'-dimethylpropyl diphenyl ether

4-hydroxy 4'-ethyl diphenyl ether

4-hydroxy 4'-nonyl diphenyl ether

4-hydroxy 4'-phenylethyl diphenyl ether

4-hydroxy 4'-propyl diphenyl ether

4-hydroxy 4'-trifluoromethyl diphenyl ether

4-hydroxy 4'-propanoyl diphenyl ether

4-hydroxy diphenyl ether

3. Device according to any one of claims 1 and 2, characterized in that the concentration of compound (s) of formula (1) varies from 0.001 to 20%, preferably from 0.01 to 15% and more preferably from 0.1 at 10% by weight relative to the total weight of the composition.

4. Device according to any one of claims 1 to 3, characterized in that the alkanes are chosen from n-butane, propane, isobutane and their mixtures.

5. Device according to any one of claims 1 to 4, characterized in that the concentration of propellant (s) varies from 5 to 90% by weight relative to the total weight of the pressurized composition.

6. Device according to any one of claims 1 to 5, characterized in that the concentration of propellant (s) varies from 15 to 70% by weight relative to the total weight of the pressurized composition.

7. Device according to any one of claims 1 to 6, characterized in that the composition containing the compound (s) of formula (1) and the propellant (s) may be in the same compartment or in different compartments in the aerosol container.

8. Device according to any one of claims 1 to 7, characterized in that the composition additionally contains at least one deodorant active and / or an antiperspirant active.

9. Device according to claim 8, characterized in that the aerosol composition contains at least one deodorant active agent chosen from zinc pyrrolidone carboxylate (more commonly called zinc pidolate), zinc sulphate, zinc chloride, lactate zinc, zinc gluconate and zinc phenoisulfonate, 2,4,4'-trichloro-2'-hydroxydiphenylether (Triclosan), 2,4-dichloro-2'-hydroxydiphenylether, 3 ', 4', 5'-trichlorosalicylanilide, 1- (3 ', 4'- dichlorophenyl) -3- (4'-chlorophenyl) urea (triclocarban) or 3,7,11- trimethyldodeca-2,5, 10-trienol (Famesol) .

10. Device according to claim 8, characterized in that the aerosol composition contains an antiperspirant active agent chosen from aluminum hydrochloride, aluminum chlorohydrex, aluminum chlorohydrex PEG, aluminum chlorohydrex PG, aluminum dichlorohydrate, aluminum dichlorohydrex PEG, aluminum dichlorohydrex PG, aluminum sesquichlorohydrate, aluminum sesquichlorohydrex PEG, aluminum sesquichlorohydrex PG, aluminum sulfate, aluminum zirconium octachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium trichlorohydrate, metal complexes with an amino acid

11. Device according to claim 10, characterized in that the amino acid used with the metal complexes is glycine.

12. Device according to claim 11, characterized in that the complexes are chosen from aluminum zirconium octachlorohydrex GLY, aluminum zirconium pentachlorohydrex GLY, aluminum zirconium tetrachlorohydrate GLY and aluminum zirconium trichlorohydrate-GLY.

13. Device according to any one of claims 8 to 12, characterized in that the deodorant or antiperspirant active agents are present in the composition in an amount of about 0.001 to 20% by weight relative to the total weight of the composition.

14. Device according to claim 13, characterized in that the deodorant or antiperspirant active agents are present in an amount of approximately 0.1 to 10% by weight relative to the total weight of the composition.

15. Device according to any one of claims 1 to 14, characterized in that the composition comprising the compound or compounds of formula (1) is formulated in a cosmetically acceptable vehicle which contains water and / or one or more solvents organic.

16. Device according to claim 15, characterized in that the organic solvent is chosen from CrC ₄ monoalcohols, propylene glycol, dipropylene glycol or their ethers.

17. Device according to claim 16, characterized in that the organic solvent is ethanol.

18. Device according to any one of claims 1 to 17, characterized in that the composition comprising the compound or compounds of formula (1) is formulated in the form Φ water-in-oil emulsion, oil-in-water, or of water-in-oil-in-water triple emulsion

19. Device according to any one of claims 1 to 18, characterized in that the composition comprising the compound or compounds of formula (1) contains one or more cosmetic adjuvants chosen from fatty substances, gelling agents, emollients, softeners, antioxidants, opacifiers, stabilizers, defoamers, moisturizers, vitamins, fragrances, preservatives, surfactants, fillers, sequestrants, polymers, propellants, alkalizing or acidifying agents , perfumes, dyes, pigments, thickening agents, or any other ingredient usually used in cosmetics.

20. Device according to any one of claims 1 to 19, characterized in that the composition comprising the compound or compounds of formula (1) is in the form of a lotion, cream or fluid gel distributed in aerosol spray.

21. A method of treating human body odors and in particular axillary odors by using the device described according to any one of claims 1 to 20.