WO2002088349A1 - Method of examining allergic disease using cathepsin-c alternative splicing form as indication - Google Patents

Method of examining allergic disease using cathepsin-c alternative splicing form as indication Download PDF

Info

Publication number
WO2002088349A1
WO2002088349A1 PCT/JP2002/004152 JP0204152W WO02088349A1 WO 2002088349 A1 WO2002088349 A1 WO 2002088349A1 JP 0204152 W JP0204152 W JP 0204152W WO 02088349 A1 WO02088349 A1 WO 02088349A1
Authority
WO
WIPO (PCT)
Prior art keywords
gene
seq
nucleotide sequence
expression level
allergic
Prior art date
Application number
PCT/JP2002/004152
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
Keiko Matsui
Noriko Ohtani
Nei Yoshida
Yuji Sugita
Kenji Izuhara
Original Assignee
Genox Research, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genox Research, Inc. filed Critical Genox Research, Inc.
Priority to JP2002585630A priority Critical patent/JPWO2002088349A1/ja
Publication of WO2002088349A1 publication Critical patent/WO2002088349A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
PCT/JP2002/004152 2001-04-27 2002-04-25 Method of examining allergic disease using cathepsin-c alternative splicing form as indication WO2002088349A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2002585630A JPWO2002088349A1 (ja) 2001-04-27 2002-04-25 カテプシンｃのオータナティブスプライシングフォームを指標とするアレルギー性疾患検査方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001131965 2001-04-27
JP2001-131965 2001-04-27

Publications (1)

Publication Number Publication Date
WO2002088349A1 true WO2002088349A1 (en) 2002-11-07

Family

ID=18980059

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/004152 WO2002088349A1 (en) 2001-04-27 2002-04-25 Method of examining allergic disease using cathepsin-c alternative splicing form as indication

Country Status (2)

Country Link
JP (1) JPWO2002088349A1 (tr)
WO (1) WO2002088349A1 (tr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038972A2 (en) * 1998-01-28 1999-08-05 Chiron Corporation Human genes and gene expression products ii

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038972A2 (en) * 1998-01-28 1999-08-05 Chiron Corporation Human genes and gene expression products ii

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GRUNIG GABRIELE ET AL.: "Requirement for IL-13 indenpendently of IL-4 in experimental asthma", SCIENCE, vol. 282, no. 5397, 1998, pages 2261 - 2263, XP002952972 *
KENJI IDEHARA: "Interleukin 4, 13 to allergy shikkan no hassho", THE JAPANESE JOURNAL OF CLINICAL PATHOLOGY, 25 April 2001 (2001-04-25), pages 360 - 364, XP002952973 *
KENJI IDEHARA: "Yakuzai receptor iden kaiseki ni yoru zensoku chiryoyaku no chiryo koka to kyakkanteki hantei ni kansuru kenkyu -inter leukin (IL-4), IL-13 no kido johi saibo ni okeru yudo indenshi no dotei ni kansuru kenkyu-", HEISEI 12 NENDO (2000), KOSE KAGAKU KENKYUHI HOJOKIN MENEKI-ALLERGY TO KENKYU JIGYO HOKOKUSHO, March 2001 (2001-03-01), pages 283 - 285, XP002952971 *

Also Published As

Publication number Publication date
JPWO2002088349A1 (ja) 2004-08-19

Similar Documents

Publication Publication Date Title
JP4185862B2 (ja) 気管支喘息の検査方法
JP4155561B2 (ja) アレルギー性疾患検査方法
EP1394274A2 (en) Methods of testing for bronchial asthma or chronic obstructive pulmonary disease
CA3138566A1 (en) Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy
AU2016361646B2 (en) Method for assessing the risk of complications in patients with systemic inflammatory response syndrome (SIRS)
US20110046202A1 (en) Method for testing a subject thought to have or to be predisposed to asthma
US20040197786A1 (en) Method of examining steroid resnponsiveness
WO2002088349A1 (en) Method of examining allergic disease using cathepsin-c alternative splicing form as indication
JP7016110B2 (ja) スティル病と敗血症との鑑別用バイオマーカー
KR101801092B1 (ko) 특발성 페섬유증 진단용 마커 조성물 및 특발성 폐섬유증 진단을 위한 정보제공방법
JP2002191398A (ja) アレルギー性疾患検査方法
WO2002064832A1 (en) Method of examining allergic disease
WO2002075304A1 (en) Method of examining allergic disease
JP2002306170A (ja) アレルギー性疾患の検査方法
US20040058351A1 (en) Method of examining for allergic disease
JPWO2004016785A1 (ja) アトピー性皮膚炎の検査方法
JP2004267090A (ja) アレルギー性疾患の検査方法
WO2003072778A1 (fr) Methode pour etudier une maladie allergique
WO2004016783A1 (ja) アトピー性皮膚炎の検査方法
JP2002095500A (ja) アレルギー性疾患の検査方法
EP1550873A1 (en) Methods for the in vitro diagnosis and prognosis of demyelinating diseases and for the development of drugs against demyelinating diseases
CN111356773A (zh) 诊断慢性阻塞性肺疾病的炎性表型的方法
JPWO2003083139A1 (ja) アレルギー性疾患の検査方法
JP2004000079A (ja) アルツハイマー病マーカー及びその利用
JPWO2004031386A1 (ja) アトピー性皮膚炎の検査方法

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA JP KR US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2002585630

Country of ref document: JP

122 Ep: pct application non-entry in european phase