WO2002085141A1 - Biologically active dietary supplement and method of its preparation - Google Patents
Biologically active dietary supplement and method of its preparation Download PDFInfo
- Publication number
- WO2002085141A1 WO2002085141A1 PCT/AM2002/000001 AM0200001W WO02085141A1 WO 2002085141 A1 WO2002085141 A1 WO 2002085141A1 AM 0200001 W AM0200001 W AM 0200001W WO 02085141 A1 WO02085141 A1 WO 02085141A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- biologically active
- dietary supplement
- apricot
- puree
- active dietary
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
Definitions
- the invention relates to biologically active dietary supplements on the basis of raw plant, namely, to dietary supplement on the basis of apricot, particularly, on the basis of Prunus armemaca L., and method of its preparation.
- Armenia is known to be the motherland of apricot. From the earliest times apricot was used in traditional Armenian medicine as means of cleaning organism from recrements.
- Unani medicine utilizes apricot as antidiarrhoeic, antipyretic, antiemetic, antihelmintic means, at biliary diseases, piles, earache, deafness [Kirtikar K.R., Basu B.D., Indian Medicinal Plants. Nol.II, M/S Periodical Experts, New Delhi, 1988, p.957], as analgesic and resolvent [Nagamoto N, Noguchi H., Nanba K., Nakamura H., zuno M., Shoyakugaku Zasshi 42, 81].
- apricot is used as dietary foodstuff - in fresh (puree), dry (dried apricots) and preserved (compote) form,
- Apricot and its dry stuff contain high amount of potassium and iron, which are necessary in ration of pregnants and anaemic patients.
- Dry stuff of apricot shows diuretic effect. It improves cerebral functioning, improves memory and working capacity, enlarges cerebral vessels. It is prescribed to patients with heart beat disorders, blood circulation deficiency, as well as to those who are treated with diuretics and cardiac glycosides in infarction, myasthenia, etc. Daily dose of lOOg dry stuff provides stool regulation [A.D.Tourova, E.N.Sapojnikova - Medicinal herbs of USSR and their use. Moscow. Medicine, 1982. pp. 249-250].
- Linolenic acid in apricot oil and fruit shows antimutagenic effect, that can be used in prophylaxis of cancer [Yamamoto, Kazuko; Osaki, Yoshiko; Kato, Tetsuta; Miyazaki, Toshio Antimutagenic substances in the Armeniacae semen and Persicae semen Yakugaku Zasshi (1992), 112(12), 934-9].
- Fresh fruits of apricot are not subject to long preserving and are not convenient for transportation, and nutritious and medicinal-preventive qualities of dry and preserved stuff from apricot are noticeably inferior to fresh apricot.
- preservation and long term drying (usually at high temperatures) causes oxidation of iron ions and a number of organic constituents of apricot.
- dry and hard stuff has a restricted sphere of application, since infants and old people, who have problems with chewing, are not able to use them.
- Biologically active dietary supplements are used together with pharmaceutical preparations or without them, for regulation of organism functioning, as well as for treatment and prophylaxis of various diseases.
- a biologically active dietary supplement in powder form from raw plant is described, that has nutritious and bio-regulatory effect [RU Patent No. 2099978].
- the aim of the present invention is to extend the raw base of biologically active dietary supplement from plant and to obtain a supplement from apricot, suitable for long preserving, transportation and use, that, in addition, preserves the flavour of a fresh fruit and valuable nutritious and medicinal-preventive qualities of plants.
- Biologically active dietary supplement according to the present invention is a dehydrated powder, obtained from puree of fresh apricots.
- the powder may be also a composition, obtained from a mixture of puree of fresh apricots and puree of other fruits (sea-buckthorn, hawthorn, hips, etc.) or extracts (liquorice, etc.) of other medicinal herbs, that also have the bio-regulatory and medicinal-preventive effect.
- the fruits, extracts and herbs cited herein are serving as an example and do not in any way limit the scope of invention.
- a method of preparation of biologically active dietary supplement from raw plant material is known, according to which the raw plant is dried, reduced to fine particles and lyopliilised, then powdered and pressed to obtain tablets [RU Patent No. 2110194],
- Biologically active dietary supplement according to present invention is obtained from apricot, particularly from Prunus armemaca L. or from a mixture of apricot and other medicinal herbs.
- the processing steps are following:
- apricot puree is lyophilised at approximately -20°C.
- purees of other fruits or herbal extracts obtained by well-known technologies, are added to the basic puree. It is also possible to dehydrate the apricot puree by spray drying at approximately 120°C.
- the obtained powder is homogenised by mixing and dispensed by tabletting, encapsulating or packing into containers.
- the purees of different ingredients of the composition are dehydrated separately.
- the obtained powders are then mixed and dispensed.
- Phenolic compounds chlorogenic acid, neochlorogenic acid, 3,4-dioxybenzoic acid, vanillin acid, (+)catechin, (-)-epicatechin, fiavonoids (rutin, hyperozid, quercetin)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Alternative & Traditional Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Preparation Of Fruits And Vegetables (AREA)
Abstract
The invention relates to biologically active dietary supplements on the basis of raw plant, namely, to dietary supplement on the basis of apricot, particularly, on the basis of Prunus armeniaca L., and method of its preparation.The suggested biologically active dietary supplement is a dehydrated powder, obtained from puree of fresh apricots. The powder may also be obtained by dehydration of puree from apricots and mixture of purees or extracts from other medicinal herbs. The obtained powder is dispensed by tabletting, encapsulating or packing into flasks. The suggested biologically active dietary supplement is subject to long preserving, suitable for transportation and use, preserves the flavour of a fresh fruit and valuable nutritious and medicinal-preventive qualities.
Description
Biologically Active Dietary Supplement and Method of its Preparation
The invention relates to biologically active dietary supplements on the basis of raw plant, namely, to dietary supplement on the basis of apricot, particularly, on the basis of Prunus armemaca L., and method of its preparation.
Armenia is known to be the motherland of apricot. From the earliest times apricot was used in traditional Armenian medicine as means of cleaning organism from recrements.
Apricot is used in traditional medicine of India and China. Thus, Unani medicine utilizes apricot as antidiarrhoeic, antipyretic, antiemetic, antihelmintic means, at biliary diseases, piles, earache, deafness [Kirtikar K.R., Basu B.D., Indian Medicinal Plants. Nol.II, M/S Periodical Experts, New Delhi, 1988, p.957], as analgesic and resolvent [Nagamoto N, Noguchi H., Nanba K., Nakamura H., zuno M., Shoyakugaku Zasshi 42, 81].
In modern medicine apricot is used as dietary foodstuff - in fresh (puree), dry (dried apricots) and preserved (compote) form,
Apricot and its dry stuff contain high amount of potassium and iron, which are necessary in ration of pregnants and anaemic patients.
Dry stuff of apricot shows diuretic effect. It improves cerebral functioning, improves memory and working capacity, enlarges cerebral vessels. It is prescribed to patients with heart beat disorders, blood circulation deficiency, as well as to those who are treated with diuretics and cardiac glycosides in infarction, myasthenia, etc. Daily dose of lOOg dry stuff provides stool regulation [A.D.Tourova, E.N.Sapojnikova - Medicinal herbs of USSR and their use. Moscow. Medicine, 1982. pp. 249-250].
Linolenic acid in apricot oil and fruit shows antimutagenic effect, that can be used in prophylaxis of cancer [Yamamoto, Kazuko; Osaki, Yoshiko; Kato, Tetsuta; Miyazaki, Toshio Antimutagenic substances in the Armeniacae semen and Persicae semen Yakugaku Zasshi (1992), 112(12), 934-9].
Fresh fruits of apricot are not subject to long preserving and are not convenient for transportation, and nutritious and medicinal-preventive qualities of dry and preserved stuff from apricot are noticeably inferior to fresh apricot. Preservation and long term drying (usually at high
temperatures) causes oxidation of iron ions and a number of organic constituents of apricot. Besides, dry and hard stuff has a restricted sphere of application, since infants and old people, who have problems with chewing, are not able to use them.
Biologically active dietary supplements are used together with pharmaceutical preparations or without them, for regulation of organism functioning, as well as for treatment and prophylaxis of various diseases. Thus, a biologically active dietary supplement in powder form from raw plant is described, that has nutritious and bio-regulatory effect [RU Patent No. 2099978].
However, until now apricot was not used as a raw material for obtaining biologically active supplements.
The aim of the present invention is to extend the raw base of biologically active dietary supplement from plant and to obtain a supplement from apricot, suitable for long preserving, transportation and use, that, in addition, preserves the flavour of a fresh fruit and valuable nutritious and medicinal-preventive qualities of plants.
Biologically active dietary supplement according to the present invention is a dehydrated powder, obtained from puree of fresh apricots.
The powder may be also a composition, obtained from a mixture of puree of fresh apricots and puree of other fruits (sea-buckthorn, hawthorn, hips, etc.) or extracts (liquorice, etc.) of other medicinal herbs, that also have the bio-regulatory and medicinal-preventive effect. The fruits, extracts and herbs cited herein are serving as an example and do not in any way limit the scope of invention.
A method of preparation of biologically active dietary supplement from raw plant material is known, according to which the raw plant is dried, reduced to fine particles and lyopliilised, then powdered and pressed to obtain tablets [RU Patent No. 2110194],
Biologically active dietary supplement according to present invention is obtained from apricot, particularly from Prunus armemaca L. or from a mixture of apricot and other medicinal herbs. The processing steps are following:
• puree is obtained from fresh apricots by known methods,
• apricot puree is lyophilised at approximately -20°C. When preparing a composition, purees of other fruits or herbal extracts, obtained by well-known technologies, are added to the basic puree.
It is also possible to dehydrate the apricot puree by spray drying at approximately 120°C. • the obtained powder is homogenised by mixing and dispensed by tabletting, encapsulating or packing into containers.
As an option of processing, the purees of different ingredients of the composition are dehydrated separately. The obtained powders are then mixed and dispensed.
Example 1
About 4 1 puree was obtained from 10 kg of fresh apricot by known methods. Apricot puree was frozen in lyophilising system LZ45 to approximately -20°C, then the pressure in the system was reduced by a vacuum generated system. The water vapours were evaporated from frozen stuff under low pressure. The obtained 1 kg of air dry powder was homogenised by mixing and dispensed by tabletting in KILIAN apparatus. As a result 2 000 of 0,5g tablets were obtained.
Example 2
About 3,6 1 of apricot and 0,4 1 of hawthorn puree was obtained respectively from 9 kg of fresh apricot fruit and 1,2 kg of hawthorn by known methods. Purees were mixed, then frozen by lyophilising system LZ45 to approximately -20°C, then the pressure in the system was reduced by a vacuum generated system. The obtained 1 kg of powder was homogenised by mixing and dispensed by tabletting in KILIAN apparatus. As a result 2000 of 0,5g tablets were obtained.
Example 3
About 4 1 of apricot puree and 0,8 1 of liquorice spissum were obtained respectively from 10 kg of fresh apricot fruit and 2 kg of liquorice. The mixture was frozen by lyophilising system LZ45 to approximately -20°C, then the pressure in the system was reduced by a vacuum generated system. The obtained 1,2 kg of powder was homogenised by mixing and dispensed by tabletting. As a result 2400 of 0,5g tablets were obtained.
Chemical composition of biologically active dietary supplement on the basis of Prunus armemaca L. (without other herbal supplements) follows. Determination is carried out by chromatomasspectroscopic method.
• Sugar: dextrose, saccharose, fructose, xylose
• Sorbitol
• Organic acids: malic acid, citric acid, fumaric acid
• Phenolic compounds: chlorogenic acid, neochlorogenic acid, 3,4-dioxybenzoic acid, vanillin acid, (+)catechin, (-)-epicatechin, fiavonoids (rutin, hyperozid, quercetin)
• Fatty acids (linolenic acid and palmitic acid) and mono-, di- and triglycerides thereof
• Phytosterines: 5,22-stygmastadienol, etc.
• Acyclic, tricyclic and pentacyclic triterpenes
• α- tocopherol (vitamin E) - 100 mg/kg
• β-carotene - 40 mg/kg
• Na+ -340 mg/kg, K+ -22100 mg/kg, Ca+2 -780 mg/kg, Mg+2 -740 mg/kg, Cu+Z -0,1 mg/kg, Zn+2 -0,4 mg/kg, NH -110 mg/kg, PO4 "3 -6500 mg/kg, Cl" -310 mg/kg, SO4 "2 -750 mg/kg
• Nolatile oils (terpenes): ortho-cymene, para-cymene, α-pinen, β-pinen, camphene, α-thujene, myrcene, sabinene, γ- terpinene, α- terpinene
• Aldehyde-hexanal
Relative characteristics of apricot puree, dry apricot and claimed biologically dietary supplement (powder)
Table
Claims
1. Biologically active dietary supplement that contains plant raw material, characterised in that plant raw material is apricot fruit or mixture of apricot fruit and fruits or extracts of other medicinal herbs.
2. Biologically active dietary supplement according to claim 1, characterised in that components of mixture with apricot fruit are sea-buckthorn, hawthorn or extract of liquorice.
3. Method of obtaining biologically active dietary supplement according to claim 1 by grinding raw material, obtaining puree, dehydrating, powdering and subsequent dispensing of obtained powder, characterised in that plant raw material is apricot fruit or mixture of apricot fruit and fruits or extracts of other medicinal herbs.
4. Method according to claim 3, characterised in that powder dispensing is realised by tabletting, encapsulating or packing into flasks.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EA200301145A EA006166B1 (en) | 2001-04-23 | 2002-04-10 | Method of preparation dehydrated powder from fresh apricots and biologically active dietary supplement containing such powder |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AM20010052 | 2001-04-23 | ||
| AMP20010052 | 2001-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2002085141A1 true WO2002085141A1 (en) | 2002-10-31 |
Family
ID=3460617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/AM2002/000001 WO2002085141A1 (en) | 2001-04-23 | 2002-04-10 | Biologically active dietary supplement and method of its preparation |
Country Status (2)
| Country | Link |
|---|---|
| EA (1) | EA006166B1 (en) |
| WO (1) | WO2002085141A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1726220A1 (en) * | 2005-05-27 | 2006-11-29 | VPF Lebensmittel GmbH & Co. KG | Freeze dried food for age groups and method for its production |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2483558C2 (en) * | 2011-03-10 | 2013-06-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Мичуринский государственный аграрный университет" (ФГБОУ ВПО МичГАУ) | Production of "boyarushka" functional purpose biokefir with natural additives |
| RU2759671C1 (en) * | 2021-04-09 | 2021-11-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Горский государственный аграрный университет" | Method for cooking the culinary product "mini-rolls of pancakes" |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2464240A (en) * | 1943-11-20 | 1949-03-15 | Ernst T Krebs | Therapeutic material and method of obtaining the same |
| US2703778A (en) * | 1952-07-10 | 1955-03-08 | Ernst T Krebs | Therapeutic emulsin complex |
| JPH04193834A (en) * | 1990-11-27 | 1992-07-13 | Meitan Honpo:Kk | Preparation of mutagenicity-suppressing agent using plant of genus prunus, family rosaceae such as plum |
| CN1083672A (en) * | 1992-11-29 | 1994-03-16 | 田后谋 | Mountain apricot with dietary function and processing method |
| JPH09238649A (en) * | 1996-03-11 | 1997-09-16 | Minato Seiyaku Kk | Production of granular food using pickled japanese apricot, soy sauce and dried root of dandelion |
| WO2001000038A1 (en) * | 1999-06-29 | 2001-01-04 | Xel Herbaceuticals | An effervescent green tea extract formulation |
-
2002
- 2002-04-10 EA EA200301145A patent/EA006166B1/en not_active IP Right Cessation
- 2002-04-10 WO PCT/AM2002/000001 patent/WO2002085141A1/en not_active Application Discontinuation
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2464240A (en) * | 1943-11-20 | 1949-03-15 | Ernst T Krebs | Therapeutic material and method of obtaining the same |
| US2703778A (en) * | 1952-07-10 | 1955-03-08 | Ernst T Krebs | Therapeutic emulsin complex |
| JPH04193834A (en) * | 1990-11-27 | 1992-07-13 | Meitan Honpo:Kk | Preparation of mutagenicity-suppressing agent using plant of genus prunus, family rosaceae such as plum |
| CN1083672A (en) * | 1992-11-29 | 1994-03-16 | 田后谋 | Mountain apricot with dietary function and processing method |
| JPH09238649A (en) * | 1996-03-11 | 1997-09-16 | Minato Seiyaku Kk | Production of granular food using pickled japanese apricot, soy sauce and dried root of dandelion |
| WO2001000038A1 (en) * | 1999-06-29 | 2001-01-04 | Xel Herbaceuticals | An effervescent green tea extract formulation |
Non-Patent Citations (3)
| Title |
|---|
| DATABASE WPI Section Ch Week 199525, Derwent World Patents Index; Class D13, AN 1995-186168, XP002210144 * |
| PATENT ABSTRACTS OF JAPAN vol. 016, no. 518 (C - 0999) 26 October 1992 (1992-10-26) * |
| PATENT ABSTRACTS OF JAPAN vol. 1998, no. 01 30 January 1998 (1998-01-30) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1726220A1 (en) * | 2005-05-27 | 2006-11-29 | VPF Lebensmittel GmbH & Co. KG | Freeze dried food for age groups and method for its production |
Also Published As
| Publication number | Publication date |
|---|---|
| EA200301145A1 (en) | 2004-06-24 |
| EA006166B1 (en) | 2005-10-27 |
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