WO2002066838A1 - Vorrichtung zur axialen förderung von körperflüssigkeiten - Google Patents

Vorrichtung zur axialen förderung von körperflüssigkeiten Download PDF

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Publication number
WO2002066838A1
WO2002066838A1 PCT/EP2002/001739 EP0201739W WO02066838A1 WO 2002066838 A1 WO2002066838 A1 WO 2002066838A1 EP 0201739 W EP0201739 W EP 0201739W WO 02066838 A1 WO02066838 A1 WO 02066838A1
Authority
WO
WIPO (PCT)
Prior art keywords
manifold
outlet
inlet
flow
hollow body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/001739
Other languages
German (de)
English (en)
French (fr)
Inventor
Peter NÜSSER
Johannes Müller
Hans-Erhard Peters
Jörg Müller
Ali Kilic
Kurt Graichen
Dietmar Ries
Klaus Wunderlich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Berlin Heart GmbH
Original Assignee
Berlin Heart GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlin Heart GmbH filed Critical Berlin Heart GmbH
Priority to EP02712918A priority Critical patent/EP1360417B1/de
Priority to CA002438379A priority patent/CA2438379C/en
Priority to JP2002566126A priority patent/JP2005507039A/ja
Priority to US10/467,974 priority patent/US7374574B2/en
Priority to DE50212568T priority patent/DE50212568D1/de
Publication of WO2002066838A1 publication Critical patent/WO2002066838A1/de
Anticipated expiration legal-status Critical
Priority to AU2006230718A priority patent/AU2006230718B2/en
Priority to AU2006230716A priority patent/AU2006230716A1/en
Ceased legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D29/00—Details, component parts, or accessories
    • F04D29/66—Combating cavitation, whirls, noise, vibration or the like; Balancing
    • F04D29/669—Combating cavitation, whirls, noise, vibration or the like; Balancing especially adapted for liquid pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
    • A61M60/178—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/408—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
    • A61M60/411—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor
    • A61M60/416—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable generated by an electromotor transmitted directly by the motor rotor drive shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/81—Pump housings
    • A61M60/812—Vanes or blades, e.g. static flow guides
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D13/00—Pumping installations or systems
    • F04D13/02—Units comprising pumps and their driving means
    • F04D13/06—Units comprising pumps and their driving means the pump being electrically driven
    • F04D13/0646—Units comprising pumps and their driving means the pump being electrically driven the hollow pump or motor shaft being the conduit for the working fluid
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D29/00—Details, component parts, or accessories
    • F04D29/40—Casings; Connections of working fluid
    • F04D29/42—Casings; Connections of working fluid for radial or helico-centrifugal pumps
    • F04D29/426—Casings; Connections of working fluid for radial or helico-centrifugal pumps especially adapted for liquid pumps
    • F04D29/4293—Details of fluid inlet or outlet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/422—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps

Definitions

  • the invention relates to a device for the axial conveyance of body fluids according to the preamble of claim 1.
  • body fluids such as blood
  • an energy input such as e.g. Emulsions and dispersions
  • Emulsions and dispersions can disadvantageously get into unstable areas when conveying in appropriate devices, such as pumps.
  • the blood represents a particularly sensitive fluid system.
  • This opaque red body fluid of the vertebrates circulates in a self-contained vascular system, whereby rhythmic contractions of the heart transfer the blood into the different areas of the
  • the blood transports the breathing gases oxygen and carbon dioxide as well as nutrients, metabolic products and the body's own active ingredients.
  • the blood vessel system including the heart is hermetically sealed from the environment
  • Hemolysis describes the state that the red blood cells within the body are destroyed beyond the physiological level. The causes of hemolysis can be mechanical or metabolic. Increased hemolysis results in multiple organ damage and can lead to death.
  • axial blood pumps which essentially consist of a cylindrical tube in which a conveying part, which is designed as a rotor of an external motor stator, is known.
  • the rotor which has a so-called blading, conveys the liquid in the axial direction after being rotated by means of the motor stator.
  • WO 00/64030 describes a device for the gentle delivery of single- or multi-phase fluids.
  • this device is in When viewed in the direction of flow, a pre-guide device is arranged in front of the conveying part (rotor) and, after the conveyed part, a downstream guide device is seen in the flow direction.
  • a pre-guide device is arranged in front of the conveying part (rotor) and, after the conveyed part, a downstream guide device is seen in the flow direction.
  • the invention is based on the object of designing the inflow region and the outflow region of an axial pump in such a way that, even when the flow is deflected in these regions, there is no flow separation, but a largely undisturbed flow profile is retained.
  • the device according to the invention for the axial conveyance of body fluids consisting of a tubular hollow body which essentially guides the liquid, is arranged in the axial orientation in which a motor-driven stator which can be set in rotation with a motor stator located outside the hollow body in a pump housing is arranged, the Conveying part has a rotor blading, and wherein upstream and downstream guiding devices are arranged in the flow direction upstream and downstream of the conveying part, and from inflow and outflow regions which are attached to the hollow body to change the flow direction are characterized in that they are arranged in the inflow region having an inlet manifold angle attached to the tubular hollow body, which has a cross-sectional reduction in the direction of the guiding device and in the outflow region having an outlet manifold angle attached to the hollow body and arranged in the flow direction up to an outlet cylinder has a reduction in cross section.
  • a flow diffuser and an outlet cannula are arranged downstream of the outlet cylinder.
  • the inlet and outlet elbows and the inlet and outlet cannulas are advantageously made of flexible material, the flexible material essentially consisting of silicone and / or reinforced silicone (fabric).
  • the flexibility of the material enables optimal operative installation of the device according to the invention and its function in the chest area.
  • the exhaust manifold and the intake manifold have only individual areas made of flexible material.
  • the radius of the intake manifold and the diameter of the intake manifold inlet are in a ratio of 1: 2.
  • the flow diffuser has a cross-sectional widening in the flow direction.
  • the inventive design of the inflow area and outflow area of a generic axial pump leads to the fact that currents can be accelerated smoothly without disturbing flow regimes.
  • the design of the intake manifold angle according to the invention which is between 45 ° 5 and 50 °, has proven to be very advantageous in relation to the change in the flow cross section.
  • the size of the exhaust manifold angle is between 85 ° and 95 °.
  • the device according to the invention experiences a special advantageous embodiment through the selection of elastic, sufficiently dimensionally stable materials, for the intake and exhaust manifolds, which thereby result in physically induced permanent movements in the area. the connection of the device to the heart chamber or to the aorta.
  • FIG. 1 is a schematic sectional view of a generic axial pump with intake and exhaust manifolds
  • Fig. 2 is a schematic sectional view of the exhaust manifold
  • Fig. 3 is a schematic sectional view of the intake manifold.
  • FIG. 1 shows a schematic illustration of an axial pump of the generic type with an inlet manifold 12 and an outlet manifold 13.
  • the inlet manifold 12 is fastened to an inflow region 10 of a cylindrical hollow body 1 with an inlet shoulder 28.
  • the outlet manifold 13 is fastened to an outflow region 11 of the cylindrical hollow body 1 with an outlet extension 29.
  • a fixed pre-guide device 6 with guide vanes 9 a suspended conveying part 2, which consists of a motor rotor 4, rotor blades 5 and a support ring 30. Seen in the flow direction after the motor rotor 4, a stationary guide device 7 with a guide vanes 16 is arranged.
  • the motor rotor 4 is set in rotation by means of a motor stator 3, which is arranged in a pump housing 8.
  • a flow diffuser 25 is provided on the exhaust manifold 13. Blood to be delivered enters and becomes via an inlet cannula 18 into an inlet cylinder 20 of the inlet manifold 12
  • the intake manifold 12 has a permanent cross-sectional constriction down to the
  • An exhaust cylinder 19 of the exhaust manifold 13 is used here as an example
  • 0 flow diffuser 25 which has a permanent cross-sectional enlargement downstream towards an outlet cannula 17. Due to the arrangement of the intake manifold 12, which redirects the blood flow at the intake manifold angle 15 and the arrangement of a
  • Fig. 2 shows a schematic sectional view of the exhaust manifold 13, which leads the blood to be delivered via a pump outlet 27, the outflow area 11 and a bend 23 into the exhaust cylinder 19 and then further into the flow diffuser 25 and the exhaust cannula 17. This way of guiding the flow becomes a Detachment of the flowing blood from an inner wall 22 of the exhaust manifold 13 is advantageously avoided.
  • the inlet manifold 12 shown in FIG. 3 in a schematic sectional view deflects the blood coming from the inlet cannula 18 via the inlet cylinder 20 by an inlet manifold angle 15 into the inlet shoulder 28.
  • the blood is then conveyed into the pump inlet 26 via the inflow region 10. Due to the permanent narrowing of the flow cross section here according to the invention, the flow was not detached from the wall 21 of the intake manifold 12.
  • Inflow area 25 Flow diffusion: Outflow area 26 Pump inlet inlet manifold 27 Pump outlet outlet manifold 28 Inlet neck

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • External Artificial Organs (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
  • Jet Pumps And Other Pumps (AREA)
  • Reciprocating Pumps (AREA)
  • Pens And Brushes (AREA)
  • Materials For Medical Uses (AREA)
PCT/EP2002/001739 2001-02-16 2002-02-18 Vorrichtung zur axialen förderung von körperflüssigkeiten Ceased WO2002066838A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP02712918A EP1360417B1 (de) 2001-02-16 2002-02-18 Vorrichtung zur axialen förderung von körperflüssigkeiten
CA002438379A CA2438379C (en) 2001-02-16 2002-02-18 Device for axially conveying body fluids
JP2002566126A JP2005507039A (ja) 2001-02-16 2002-02-18 体液の軸方向搬送のための装置
US10/467,974 US7374574B2 (en) 2001-02-16 2002-02-18 Device for axially conveying body fluids
DE50212568T DE50212568D1 (de) 2001-02-16 2002-02-18 Vorrichtung zur axialen förderung von körperflüssigkeiten
AU2006230718A AU2006230718B2 (en) 2001-02-16 2006-10-20 Device for axially conveying body fluids
AU2006230716A AU2006230716A1 (en) 2001-02-16 2006-10-20 Device for axially conveying body fluids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10108815A DE10108815B4 (de) 2001-02-16 2001-02-16 Vorrichtung zur axialen Förderung von Körperflüssigkeiten
DE10108815.9 2001-02-16

Publications (1)

Publication Number Publication Date
WO2002066838A1 true WO2002066838A1 (de) 2002-08-29

Family

ID=7675284

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/001739 Ceased WO2002066838A1 (de) 2001-02-16 2002-02-18 Vorrichtung zur axialen förderung von körperflüssigkeiten

Country Status (10)

Country Link
US (1) US7374574B2 (https=)
EP (1) EP1360417B1 (https=)
JP (2) JP2005507039A (https=)
CN (2) CN1873232A (https=)
AT (1) ATE403087T1 (https=)
AU (1) AU2006230716A1 (https=)
CA (1) CA2438379C (https=)
DE (2) DE10108815B4 (https=)
RU (1) RU2314835C2 (https=)
WO (1) WO2002066838A1 (https=)

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CN103195758A (zh) * 2013-04-07 2013-07-10 江苏大学 一种用于轴流泵叶轮进口横截面piv流场测量的进口装置
CN109414533A (zh) * 2016-05-02 2019-03-01 韦德威申思有限公司 心脏辅助装置

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EP3833410B1 (de) 2018-08-07 2025-10-08 Kardion GmbH Lagervorrichtung für ein herzunterstützungssystem und verfahren zum spülen eines zwischenraums in einer lagervorrichtung für ein herzunterstützungssystem
CN110173463B (zh) * 2019-05-16 2020-10-16 山东洪涨泵业有限公司 一种一进两出净化式管道增压离心泵
DE102020102474A1 (de) 2020-01-31 2021-08-05 Kardion Gmbh Pumpe zum Fördern eines Fluids und Verfahren zum Herstellen einer Pumpe
AU2021340802A1 (en) 2020-09-14 2023-05-18 Kardion Gmbh Cardiovascular support pump having an impeller with a variable flow area
AU2021383931A1 (en) 2020-11-20 2023-07-06 Kardion Gmbh Mechanical circulatory support system with guidewire aid
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CN115120866A (zh) * 2022-06-29 2022-09-30 利为惠德无锡医疗科技有限公司 一种植入式人工心脏的入管弯头及人工心脏
CN116593193B (zh) * 2023-04-20 2026-02-17 北京航空航天大学 一种微型介入泵的体外测试装置

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WO2000064030A1 (de) 1999-04-20 2000-10-26 Berlin Heart Ag Vorrichtung zur schonenden förderung von ein- oder mehrphasigen fluiden

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103195758A (zh) * 2013-04-07 2013-07-10 江苏大学 一种用于轴流泵叶轮进口横截面piv流场测量的进口装置
CN109414533A (zh) * 2016-05-02 2019-03-01 韦德威申思有限公司 心脏辅助装置
US10918774B2 (en) 2016-05-02 2021-02-16 Vadovations, Inc. Heart assist device
US11904155B2 (en) 2016-05-02 2024-02-20 Star Bp, Inc. Heart assist device

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CA2438379C (en) 2008-09-23
DE50212568D1 (de) 2008-09-11
EP1360417A1 (de) 2003-11-12
DE10108815A1 (de) 2002-10-02
AU2006230716A1 (en) 2006-11-09
CN1267647C (zh) 2006-08-02
RU2003124639A (ru) 2005-02-27
CN1873232A (zh) 2006-12-06
JP2008248884A (ja) 2008-10-16
ATE403087T1 (de) 2008-08-15
DE10108815B4 (de) 2006-03-16
CA2438379A1 (en) 2002-08-29
US20040116776A1 (en) 2004-06-17
JP2005507039A (ja) 2005-03-10
EP1360417B1 (de) 2008-07-30
RU2314835C2 (ru) 2008-01-20
US7374574B2 (en) 2008-05-20
CN1491324A (zh) 2004-04-21

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