WO2002058725A3 - Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin - Google Patents

Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin Download PDF

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Publication number
WO2002058725A3
WO2002058725A3 PCT/FR2002/000270 FR0200270W WO02058725A3 WO 2002058725 A3 WO2002058725 A3 WO 2002058725A3 FR 0200270 W FR0200270 W FR 0200270W WO 02058725 A3 WO02058725 A3 WO 02058725A3
Authority
WO
WIPO (PCT)
Prior art keywords
rsv
vaccine
protein
peptides derived
glycosylated peptides
Prior art date
Application number
PCT/FR2002/000270
Other languages
English (en)
Other versions
WO2002058725A2 (fr
Inventor
Ultan Power
Guyen Thien Ngoc N
Original Assignee
Pf Medicament
Ultan Power
Guyen Thien Ngoc N
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament, Ultan Power, Guyen Thien Ngoc N filed Critical Pf Medicament
Priority to EP02700379A priority Critical patent/EP1353690A2/fr
Priority to AU2002233457A priority patent/AU2002233457A1/en
Publication of WO2002058725A2 publication Critical patent/WO2002058725A2/fr
Publication of WO2002058725A3 publication Critical patent/WO2002058725A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

La présente invention se rapporte au virus respiratoire syncytial, et plus particulièrement à l'identification de nouveaux antigènes non glycosylés, utiles notamment pour le traitement thérapeutique et prophylactique des affections provoquées par ce virus.
PCT/FR2002/000270 2001-01-23 2002-01-23 Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin WO2002058725A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02700379A EP1353690A2 (fr) 2001-01-23 2002-01-23 Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin
AU2002233457A AU2002233457A1 (en) 2001-01-23 2002-01-23 Non-glycosylated peptides derived from the rsv g protein and use thereof in a vaccine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR01/00875 2001-01-23
FR0100875A FR2819810B1 (fr) 2001-01-23 2001-01-23 Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin

Publications (2)

Publication Number Publication Date
WO2002058725A2 WO2002058725A2 (fr) 2002-08-01
WO2002058725A3 true WO2002058725A3 (fr) 2003-01-09

Family

ID=8859130

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2002/000270 WO2002058725A2 (fr) 2001-01-23 2002-01-23 Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin

Country Status (4)

Country Link
EP (1) EP1353690A2 (fr)
AU (1) AU2002233457A1 (fr)
FR (1) FR2819810B1 (fr)
WO (1) WO2002058725A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9211342B2 (en) 2010-01-22 2015-12-15 Novo Nordisk Healthcare Ag Stable growth hormone compounds resistant to proteolytic degradation

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7368537B2 (en) * 2003-07-15 2008-05-06 Id Biomedical Corporation Of Quebec Subunit vaccine against respiratory syncytial virus infection
TW200522976A (en) * 2003-09-19 2005-07-16 Novo Nordisk As Novel plasma protein affinity tags
KR101241862B1 (ko) * 2003-09-19 2013-03-13 노보 노르디스크 에이/에스 신규 ｇｌｐ-1 유도체
WO2006097538A1 (fr) 2005-03-18 2006-09-21 Novo Nordisk A/S Composes glp-1 avances
TWI372629B (en) 2005-03-18 2012-09-21 Novo Nordisk As Acylated glp-1 compounds
CA2733200A1 (fr) 2008-08-06 2010-02-11 Novo Nordisk Health Care Ag Proteines conjuguees a efficacite in vivo prolongee
CN102292349B (zh) 2009-01-22 2016-04-13 诺沃—诺迪斯克保健股份有限公司 稳定的生长激素化合物
CN102612376A (zh) 2009-08-06 2012-07-25 诺沃-诺迪斯克保健股份有限公司 具有延长的体内功效的生长激素
CN106139158A (zh) 2010-01-22 2016-11-23 诺沃—诺迪斯克保健股份有限公司 体内功效延长的生长激素
EP2590675B1 (fr) 2010-07-07 2018-08-29 Artificial Cell Technologies, Inc. Compositions antigéniques du virus respiratoire syncytial et méthodes associées
US11045523B2 (en) 2013-04-05 2021-06-29 Novo Nordisk Healthcare Ag Formulation of growth hormone albumin-binder conjugate
WO2024084785A1 (fr) * 2022-10-20 2024-04-25 一般財団法人阪大微生物病研究会 Composition appropriée pour être utilisée en tant que vaccin contre le virus rs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995027787A1 (fr) * 1994-04-06 1995-10-19 Pierre Fabre Medicament Fragment peptidique de la proteine g du virus respiratoire syncytial, agent immunogene, composition pharmaceutique le contenant et procede de preparation
WO1996014409A1 (fr) * 1994-11-07 1996-05-17 Pierre Fabre Medicament Production de peptides recombinants, analogues de peptides naturels hydrophobes
WO1999003987A2 (fr) * 1997-07-17 1999-01-28 Pierre Fabre Medicament Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995027787A1 (fr) * 1994-04-06 1995-10-19 Pierre Fabre Medicament Fragment peptidique de la proteine g du virus respiratoire syncytial, agent immunogene, composition pharmaceutique le contenant et procede de preparation
WO1996014409A1 (fr) * 1994-11-07 1996-05-17 Pierre Fabre Medicament Production de peptides recombinants, analogues de peptides naturels hydrophobes
WO1999003987A2 (fr) * 1997-07-17 1999-01-28 Pierre Fabre Medicament Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
POWER U.F. ET AL.: "Differential histopathology and chemokine gene expression in lung tissues following respiratory syncitial virus (RSV) challenge of formalin-inactivated RSV- or BBG2Na-imunized mice.", J. VIROL., vol. 75, no. 24, December 2001 (2001-12-01), pages 12421 - 12430, XP002203747 *
POWER U.F. ET AL.: "Induction of protective immunity in rodents by vaccination with a procaryotically expressed recombinant fusion protein containing a respiratory syncytial virus G protein fragment.", VIROLOGY, vol. 230, 1997, pages 155 - 166, XP002179365 *
SIEGRIST C.A. ET AL.: "Protective efficacy aganst respiratory syncytial virus following murine neonatan immunization with BBG2Na vaccine: influence of adjuvants and materna antibodies.", J. INFECT. DIS., vol. 179, 1999, pages 1326 - 1333, XP002179366 *
SIMARD C. ET AL.: "Evidence that the amino acid region 124-203 of glycoprotein G from the respiratory syncytial virus (RSV) constitutes a major part of the polypeptide domain that is involved in the protection against RSV infection", ANTIVIRAL RES., vol. 28, no. 4, 1995, pages 303 - 305, XP000565377 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9211342B2 (en) 2010-01-22 2015-12-15 Novo Nordisk Healthcare Ag Stable growth hormone compounds resistant to proteolytic degradation

Also Published As

Publication number Publication date
FR2819810B1 (fr) 2004-05-28
FR2819810A1 (fr) 2002-07-26
EP1353690A2 (fr) 2003-10-22
AU2002233457A1 (en) 2002-08-06
WO2002058725A2 (fr) 2002-08-01

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