WO2002057746A3 - Specimen slide, microdissection device comprising a specimen slide and a microdissection method - Google Patents

Specimen slide, microdissection device comprising a specimen slide and a microdissection method Download PDF

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Publication number
WO2002057746A3
WO2002057746A3 PCT/DE2002/000056 DE0200056W WO02057746A3 WO 2002057746 A3 WO2002057746 A3 WO 2002057746A3 DE 0200056 W DE0200056 W DE 0200056W WO 02057746 A3 WO02057746 A3 WO 02057746A3
Authority
WO
WIPO (PCT)
Prior art keywords
specimen slide
microdissection
thickness
specimen
slide
Prior art date
Application number
PCT/DE2002/000056
Other languages
German (de)
French (fr)
Other versions
WO2002057746A2 (en
Inventor
Albrecht Weiss
Michael Ganser
Original Assignee
Leica Microsystems
Albrecht Weiss
Michael Ganser
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leica Microsystems, Albrecht Weiss, Michael Ganser filed Critical Leica Microsystems
Priority to DE10290161T priority Critical patent/DE10290161D2/en
Priority to AU2002233157A priority patent/AU2002233157A1/en
Publication of WO2002057746A2 publication Critical patent/WO2002057746A2/en
Publication of WO2002057746A3 publication Critical patent/WO2002057746A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N2001/045—Laser ablation; Microwave vaporisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving
    • G01N2001/2886—Laser cutting, e.g. tissue catapult
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

The invention relates to a specimen slide (1) for microscopic preparations (3). The specimen slide (1) defines a total area, has a first thickness (13), and is characterized in that it has, over a portion of its total surface, a second thickness (7) that is significantly smaller than the first thickness (13).
PCT/DE2002/000056 2001-01-18 2002-01-10 Specimen slide, microdissection device comprising a specimen slide and a microdissection method WO2002057746A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE10290161T DE10290161D2 (en) 2001-01-18 2002-01-10 Slide, microdissection device with slide and method for microdissection
AU2002233157A AU2002233157A1 (en) 2001-01-18 2002-01-10 Specimen slide, microdissection device comprising a specimen slide and a microdissection method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10102034.1 2001-01-18
DE2001102034 DE10102034A1 (en) 2001-01-18 2001-01-18 Slide, microdissection device with slide and method for microdissection

Publications (2)

Publication Number Publication Date
WO2002057746A2 WO2002057746A2 (en) 2002-07-25
WO2002057746A3 true WO2002057746A3 (en) 2002-11-21

Family

ID=7670908

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2002/000056 WO2002057746A2 (en) 2001-01-18 2002-01-10 Specimen slide, microdissection device comprising a specimen slide and a microdissection method

Country Status (3)

Country Link
AU (1) AU2002233157A1 (en)
DE (2) DE10102034A1 (en)
WO (1) WO2002057746A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10156501B2 (en) 2001-11-05 2018-12-18 Life Technologies Corporation Automated microdissection instrument for determining a location of a laser beam projection on a worksurface area
US7456938B2 (en) * 2003-11-07 2008-11-25 Mds Analytical Technologies (Us) Inc. Laser microdissection on inverted polymer films
DE10300091A1 (en) * 2003-01-04 2004-07-29 Lubatschowski, Holger, Dr. microtome
WO2012102779A2 (en) 2011-01-24 2012-08-02 Adey Nils B Devices, systems, and methods for extracting a material from a material sample
EP3250900B1 (en) 2015-01-31 2021-08-18 Roche Diagnostics GmbH Systems and methods for meso-dissection
WO2016120433A1 (en) 2015-01-31 2016-08-04 Roche Diagnostics Gmbh Systems and methods for meso-dissection
WO2018087155A1 (en) 2016-11-09 2018-05-17 F. Hoffmann-La Roche Ag Automated tissue dissection instrument and methods of using the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585644A (en) * 1994-12-19 1996-12-17 U.S. Philips Corporation Polyethylene naphthalate X-ray window
US5998129A (en) * 1996-02-05 1999-12-07 P.A.L.M. Gmbh Method and device for the contactless laser-assisted microinjection, sorting and production of biological objects generated in a planar manner
DE10039979A1 (en) * 2000-08-16 2002-03-07 P A L M Gmbh Carrier device for a preparation for separating individual objects from the preparation by means of laser radiation
EP1207392A1 (en) * 2000-11-17 2002-05-22 Leica Microsystems Wetzlar GmbH Device for holding thin slices

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19616216A1 (en) * 1996-04-23 1997-10-30 P A L M Gmbh Laser beam process and assembly separates individual cells from tissue mass
DE19818425A1 (en) * 1997-10-18 1999-07-15 Malte Dr Med Boehm Microdissection sample handling device for histology or cytology

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585644A (en) * 1994-12-19 1996-12-17 U.S. Philips Corporation Polyethylene naphthalate X-ray window
US5998129A (en) * 1996-02-05 1999-12-07 P.A.L.M. Gmbh Method and device for the contactless laser-assisted microinjection, sorting and production of biological objects generated in a planar manner
DE10039979A1 (en) * 2000-08-16 2002-03-07 P A L M Gmbh Carrier device for a preparation for separating individual objects from the preparation by means of laser radiation
EP1207392A1 (en) * 2000-11-17 2002-05-22 Leica Microsystems Wetzlar GmbH Device for holding thin slices

Also Published As

Publication number Publication date
WO2002057746A2 (en) 2002-07-25
DE10290161D2 (en) 2004-04-15
AU2002233157A1 (en) 2002-07-30
DE10102034A1 (en) 2002-08-08

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