WO2002048396A3 - Sensor zur detektion von makromolekularen biopolymeren - Google Patents

Sensor zur detektion von makromolekularen biopolymeren Download PDF

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Publication number
WO2002048396A3
WO2002048396A3 PCT/DE2001/004719 DE0104719W WO0248396A3 WO 2002048396 A3 WO2002048396 A3 WO 2002048396A3 DE 0104719 W DE0104719 W DE 0104719W WO 0248396 A3 WO0248396 A3 WO 0248396A3
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WO
WIPO (PCT)
Prior art keywords
sensor
radiation detector
macromolecular biopolymers
detecting macromolecular
adhesive layer
Prior art date
Application number
PCT/DE2001/004719
Other languages
English (en)
French (fr)
Other versions
WO2002048396A2 (de
Inventor
Franz Hofmann
Richard Johannes Luyken
Martin Steibl
Petra Theresia Schindler-Bauer
Original Assignee
Infineon Technologies Ag
Franz Hofmann
Richard Johannes Luyken
Martin Steibl
Petra Theresia Schindler-Bauer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infineon Technologies Ag, Franz Hofmann, Richard Johannes Luyken, Martin Steibl, Petra Theresia Schindler-Bauer filed Critical Infineon Technologies Ag
Publication of WO2002048396A2 publication Critical patent/WO2002048396A2/de
Publication of WO2002048396A3 publication Critical patent/WO2002048396A3/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

Der Sensor zur Detektion von makromolekularen Biomolekülen weist einen Strahlungsdetektor und eine über der strahlunsempfinlichen Seite des Strahlunsdetektors angeordnete strahlunsdurchlässige Haftschicht auf, die derart ausgebildet ist, dass Fängermoleküle an der Haftschicht gebunden werden können. Anhand der Ausertung von Strahlunsdetektor- Ausgangssignalen kann auf die Existenz von zu der Struktur der Fängermoleküle komplementären bzw. spezifischen makromolekularen Biomolekülen in der zu untersuchenden Lösung geschlossen werden.
PCT/DE2001/004719 2000-12-14 2001-12-14 Sensor zur detektion von makromolekularen biopolymeren WO2002048396A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10062244A DE10062244A1 (de) 2000-12-14 2000-12-14 Sensor zur Detektion von makromolekularen Biopolymeren, Sensoranordnung, Verfahren zur Detektion von makromolekularen Biopolymeren und Verfahren zum Herstellen eines Sensors zur Detektion von makromolekularen Biopolymeren
DE10062244.5 2000-12-14

Publications (2)

Publication Number Publication Date
WO2002048396A2 WO2002048396A2 (de) 2002-06-20
WO2002048396A3 true WO2002048396A3 (de) 2003-09-04

Family

ID=7667075

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2001/004719 WO2002048396A2 (de) 2000-12-14 2001-12-14 Sensor zur detektion von makromolekularen biopolymeren

Country Status (2)

Country Link
DE (1) DE10062244A1 (de)
WO (1) WO2002048396A2 (de)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0402917A2 (de) * 1989-06-15 1990-12-19 Biocircuits Corporation Biosensoren, die elektrische, optische und mechanische Signale verwenden
US5814516A (en) * 1995-10-13 1998-09-29 Lockheed Martin Energy Systems, Inc. Surface enhanced Raman gene probe and methods thereof
US5843651A (en) * 1994-09-22 1998-12-01 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
WO1998058079A1 (en) * 1997-06-18 1998-12-23 Krull Ulrich J Nucleic acid biosensor diagnostics
DE19808003A1 (de) * 1998-02-26 1999-09-09 Weller Verfahren zur Beschleunigung der Dissoziation von Komplexen
WO2001075150A2 (de) * 2000-03-30 2001-10-11 Infineon Technologies Ag Biosensor, biosensor-array, verfahren zum herstellen einer elektrode eines biosensors, verfahren zum herstellen eines biosensors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19940749A1 (de) * 1998-08-28 2000-05-18 Febit Ferrarius Biotech Gmbh Verfahren und Vorrichtung zur integrierten Synthese und Analyse von Polymeren

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0402917A2 (de) * 1989-06-15 1990-12-19 Biocircuits Corporation Biosensoren, die elektrische, optische und mechanische Signale verwenden
US5843651A (en) * 1994-09-22 1998-12-01 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
US5814516A (en) * 1995-10-13 1998-09-29 Lockheed Martin Energy Systems, Inc. Surface enhanced Raman gene probe and methods thereof
WO1998058079A1 (en) * 1997-06-18 1998-12-23 Krull Ulrich J Nucleic acid biosensor diagnostics
DE19808003A1 (de) * 1998-02-26 1999-09-09 Weller Verfahren zur Beschleunigung der Dissoziation von Komplexen
WO2001075150A2 (de) * 2000-03-30 2001-10-11 Infineon Technologies Ag Biosensor, biosensor-array, verfahren zum herstellen einer elektrode eines biosensors, verfahren zum herstellen eines biosensors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PIUNNO P A E ET AL: "FIBER-OPTIC DNA SENSOR FOR FLUOROMETRIC NUCLEIC ACID DETERMINATION", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 67, no. 15, 1 August 1995 (1995-08-01), pages 2635 - 2643, XP000520162, ISSN: 0003-2700 *
VO-DINH T: "Development of a DNA biochip: principle and applications", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 51, no. 1-3, 31 August 1998 (1998-08-31), pages 52 - 59, XP004153989, ISSN: 0925-4005 *

Also Published As

Publication number Publication date
DE10062244A1 (de) 2002-07-04
WO2002048396A2 (de) 2002-06-20

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