WO2002044710A3 - Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse - Google Patents

Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse Download PDF

Info

Publication number
WO2002044710A3
WO2002044710A3 PCT/FR2001/003760 FR0103760W WO0244710A3 WO 2002044710 A3 WO2002044710 A3 WO 2002044710A3 FR 0103760 W FR0103760 W FR 0103760W WO 0244710 A3 WO0244710 A3 WO 0244710A3
Authority
WO
WIPO (PCT)
Prior art keywords
micro
chromatograph
mass spectrometer
capillary tube
flow rate
Prior art date
Application number
PCT/FR2001/003760
Other languages
English (en)
Other versions
WO2002044710A2 (fr
Inventor
Jean-Louis Gass
Ronan Cozic
Georges Ponchin
Original Assignee
Commissariat Energie Atomique
Centre Nat Rech Scient
Jean-Louis Gass
Ronan Cozic
Georges Ponchin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique, Centre Nat Rech Scient, Jean-Louis Gass, Ronan Cozic, Georges Ponchin filed Critical Commissariat Energie Atomique
Priority to JP2002546204A priority Critical patent/JP3834550B2/ja
Priority to EP01998818A priority patent/EP1337843A2/fr
Priority to CA002397898A priority patent/CA2397898C/fr
Priority to IL15076901A priority patent/IL150769A0/xx
Priority to AU2002222070A priority patent/AU2002222070A1/en
Priority to US10/181,556 priority patent/US6907768B2/en
Publication of WO2002044710A2 publication Critical patent/WO2002044710A2/fr
Priority to IL150769A priority patent/IL150769A/en
Publication of WO2002044710A3 publication Critical patent/WO2002044710A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7206—Mass spectrometers interfaced to gas chromatograph
    • G01N30/7213—Mass spectrometers interfaced to gas chromatograph splitting of the gaseous effluent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/30—Control of physical parameters of the fluid carrier of temperature
    • G01N2030/3038—Control of physical parameters of the fluid carrier of temperature temperature control of column exit, e.g. of restrictors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7206—Mass spectrometers interfaced to gas chromatograph
    • G01N2030/7226—OWTC, short capillaries or transfer line used as column

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

Dispositif de couplage reliant la sortie d'un microchromatographe (à) à l'entrée d'un spectromètre de masse (SM), ledit dispositif de couplage comprenant un tube capillaire dont l'une des extrémités est raccordée de façon étanche à la source sous vide du spectromètre de masse par l'intermédiaire d'un dispositif d'interface, et dont l'autre extrémité est raccordée à la sortie du microchromatographe, de manière lâche, ouverte sur l'atmosphère ; la longueur et le diamètre du tube capillaire étant choisis pour que le débit à l'intérieur du tube capillaire soit très voisin du débit à la sortie du microchromatographe; le dispositif d'interface étant, en outre, muni de moyens de chauffage pour ajuster très précisément le débit prélevé par le capillaire.
PCT/FR2001/003760 2000-11-29 2001-11-28 Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse WO2002044710A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2002546204A JP3834550B2 (ja) 2000-11-29 2001-11-28 マイクロクロマトグラフと質量スペクトル計とを結合するためのデバイスならびに分析デバイス
EP01998818A EP1337843A2 (fr) 2000-11-29 2001-11-28 Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse
CA002397898A CA2397898C (fr) 2000-11-29 2001-11-28 Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse
IL15076901A IL150769A0 (en) 2000-11-29 2001-11-28 Device for coupling a micro-chromatograph with a mass spectrometer and analysis device
AU2002222070A AU2002222070A1 (en) 2000-11-29 2001-11-28 Device for coupling a micro-chromatograph with a mass spectrometer and analysis device
US10/181,556 US6907768B2 (en) 2000-11-29 2001-11-29 Device for coupling a microchromatograph with a mass spectrometer and analysis device
IL150769A IL150769A (en) 2000-11-29 2002-07-16 A device for attaching a microchromatic graph to a mass spectrometer and an analysis device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015415A FR2817347B1 (fr) 2000-11-29 2000-11-29 Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse
FR0015415 2000-11-29

Publications (2)

Publication Number Publication Date
WO2002044710A2 WO2002044710A2 (fr) 2002-06-06
WO2002044710A3 true WO2002044710A3 (fr) 2003-02-20

Family

ID=8857007

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2001/003760 WO2002044710A2 (fr) 2000-11-29 2001-11-28 Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse

Country Status (8)

Country Link
US (1) US6907768B2 (fr)
EP (1) EP1337843A2 (fr)
JP (1) JP3834550B2 (fr)
AU (1) AU2002222070A1 (fr)
CA (1) CA2397898C (fr)
FR (1) FR2817347B1 (fr)
IL (2) IL150769A0 (fr)
WO (1) WO2002044710A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2849924B1 (fr) * 2003-01-14 2005-02-11 Commissariat Energie Atomique Dispositif de couplage automatise entre un micro-chromatographe et un spectrometre de masse comprenant un ajustement de temperature
JP4569160B2 (ja) * 2004-04-28 2010-10-27 東洋製罐株式会社 クロマトグラフ質量分析装置
US7964411B2 (en) * 2007-06-12 2011-06-21 Dionex Corporation Membrane based concentrators
NL2002365C2 (en) * 2008-05-26 2011-04-05 Avantium Holding B V Flow splitter and reaction assembly.
US8549893B2 (en) * 2009-03-06 2013-10-08 Thermo Finnigan Llc System and method for a gas chromatograph to mass spectrometer interface
WO2014132357A1 (fr) * 2013-02-27 2014-09-04 株式会社島津製作所 Spectromètre de masse
US9590583B2 (en) 2015-06-29 2017-03-07 Agilent Technologies, Inc. Alternating current (AC) coupler for wideband AC signals and related methods
CN105403613B (zh) * 2015-10-23 2018-12-14 中国科学技术大学 真空分步加热-元素-同位素富集分析装置
CN105372365B (zh) * 2015-10-30 2017-03-29 中国烟草总公司郑州烟草研究院 一种在线检测卷烟烟气中环氧乙烷和环氧丙烷的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997023779A1 (fr) * 1995-12-23 1997-07-03 The University Court Of The University Of Dundee Systeme d'entree de gaz

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4662914A (en) * 1985-03-18 1987-05-05 Hewlett-Packard Company Flow-limited direct GC/MS interface

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997023779A1 (fr) * 1995-12-23 1997-07-03 The University Court Of The University Of Dundee Systeme d'entree de gaz

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HENNEBERG D ET AL: "HIGH-PERFORMANCE GAS CHROMATOGRAPH-MASS SPECTROMETER INTERFACING: INVESTIGATION AND OPTIMIZATION OF FLOW AND TEMPERATURE", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 167, 1978, pages 139 - 147, XP000993588, ISSN: 0021-9673 *
HENNEBERG D ET AL: "SPECIAL TECHNIQUES IN THE COMBINATION OF GAS CHROMATOGRAPHY AND MASS SPECTROMETRY", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 112, 1975, pages 343 - 352, XP000993587, ISSN: 0021-9673 *

Also Published As

Publication number Publication date
EP1337843A2 (fr) 2003-08-27
CA2397898C (fr) 2008-08-12
US6907768B2 (en) 2005-06-21
IL150769A (en) 2006-06-11
JP3834550B2 (ja) 2006-10-18
AU2002222070A1 (en) 2002-06-11
FR2817347A1 (fr) 2002-05-31
CA2397898A1 (fr) 2002-06-06
US20040025566A1 (en) 2004-02-12
JP2004514905A (ja) 2004-05-20
WO2002044710A2 (fr) 2002-06-06
IL150769A0 (en) 2003-02-12
FR2817347B1 (fr) 2003-01-03

Similar Documents

Publication Publication Date Title
WO2002044710A3 (fr) Dispositif de couplage d'un microchromatographe avec un spectrometre de masse et dispositif d'analyse
WO2005096720A3 (fr) Emetteur capillaire destine a la spectrometrie de masse par electronebulisation
WO2004009202A3 (fr) Pre-concentrateur d'analyte pour chromatographie en phase gazeuse
CA2538266A1 (fr) Robinet a manchon
WO2000022409A3 (fr) Dispositifs microfluidiques connectes a des capillaires en minimisant le volume inutilise
EP1500937A4 (fr) Instrument d'analyse, procede d'analyse d'echantillon et dispositif d'analyse utilisant un tel instrument, procede de formation d'ouverture dans l'instrument
ATE285048T1 (de) Abgedichtete kupplung
WO2000036391A3 (fr) Sonde a ultrasons pour tres hautes temperatures et tres hautes pressions
EP1243900A3 (fr) Débitmètre optique
DK0445352T3 (da) Indretning til fleksibel, gastæt forbindelse af ledninger
AUPQ219799A0 (en) Apparatus for obtaining potological samples
IL169179A0 (en) Device for automated coupling between a micro-chromatograph and a mass spectrometer comprising temperature adjustment
WO1997047951A8 (fr) Generateur de chaleur avec fonction de densite de chauffe conique pour debitmetre massique
WO2002036998A3 (fr) Vanne a manchon
EP1056119A3 (fr) Dispositif de partie froide d'une lampe à décharge dans la vapeur de mercure à basse pression
WO2002029365A3 (fr) Capteur resistant au gel
SE0004574D0 (sv) Electrospray interface
EP1496341A3 (fr) Débitmètre massique de Coriolis et procédé de commande d'un débitmètre massique de Coriolis
EP1688713A3 (fr) Vanne de réglage d'écoulement avec débitmètre
PT1051785E (pt) Dispositivo de direccionamento de tubos
ZA200006455B (en) A device for controlling the flow of plastics material, heated until flowable, through a housing.
DK1300114T3 (da) Evakueringsindretning til et blodpröverör
SE8404840L (sv) Anordning for insleppning av provmedium till en masspektrometer
SE9803330D0 (sv) Gasanslutningsdon
ATE420566T1 (de) System zur handhabung von asche

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 150769

Country of ref document: IL

Ref document number: 2001998818

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2002 546204

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2397898

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 10181556

Country of ref document: US

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWP Wipo information: published in national office

Ref document number: 2001998818

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642