WO2002015951A3 - Coated vascular grafts and methods of use - Google Patents

Coated vascular grafts and methods of use Download PDF

Info

Publication number
WO2002015951A3
WO2002015951A3 PCT/US2001/025880 US0125880W WO0215951A3 WO 2002015951 A3 WO2002015951 A3 WO 2002015951A3 US 0125880 W US0125880 W US 0125880W WO 0215951 A3 WO0215951 A3 WO 0215951A3
Authority
WO
WIPO (PCT)
Prior art keywords
graft
coating
thoralon
polyurethane
core zone
Prior art date
Application number
PCT/US2001/025880
Other languages
French (fr)
Other versions
WO2002015951A2 (en
Inventor
Ramesh B Jayaraman
Christofer T Christoforou
Original Assignee
Thoratec Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thoratec Corp filed Critical Thoratec Corp
Priority to DE60115712T priority Critical patent/DE60115712T2/en
Priority to EP01964174A priority patent/EP1365819B1/en
Priority to AU2001285059A priority patent/AU2001285059A1/en
Publication of WO2002015951A2 publication Critical patent/WO2002015951A2/en
Publication of WO2002015951A3 publication Critical patent/WO2002015951A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A vascular graft, such as an AAA stent graft, includes a core zone of PET fabric with a non-porous coating comprising a polyurethane, such as Thoralon®, disposed on at least one surface. The coating provides a barrier to prevent short and long term leakage of fluids through the pores of the PET fabric core zone. A method for sealing the pores of a porous PET graft includes the step of coating at least one surface of said graft with at least one polyurethane, or mixtures and combinations thereof. Preferably, the coating is Thoralon®. A method for making a vascular prosthesis includes the steps of providing a core zone of with at least one polyurethane, or mixtures and combinations thereof, such as Thoralon®. Finally, a method of repairing or treating a defective vessel includes the step of reinforcing or replacing the defective vessel with a graft according to the invention.
PCT/US2001/025880 2000-08-23 2001-08-20 Coated vascular grafts and methods of use WO2002015951A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60115712T DE60115712T2 (en) 2000-08-23 2001-08-20 COATED TUBE TRANSPLANTS AND USE METHOD
EP01964174A EP1365819B1 (en) 2000-08-23 2001-08-20 Coated vascular grafts and methods of use
AU2001285059A AU2001285059A1 (en) 2000-08-23 2001-08-20 Coated vascular grafts and methods of use

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US22689700P 2000-08-23 2000-08-23
US60/226,897 2000-08-23
US23846900P 2000-10-10 2000-10-10
US60/238,469 2000-10-10
US09/933,256 2001-08-20
US09/933,256 US6939377B2 (en) 2000-08-23 2001-08-20 Coated vascular grafts and methods of use

Publications (2)

Publication Number Publication Date
WO2002015951A2 WO2002015951A2 (en) 2002-02-28
WO2002015951A3 true WO2002015951A3 (en) 2003-09-25

Family

ID=27397671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/025880 WO2002015951A2 (en) 2000-08-23 2001-08-20 Coated vascular grafts and methods of use

Country Status (6)

Country Link
US (1) US6939377B2 (en)
EP (1) EP1365819B1 (en)
AU (1) AU2001285059A1 (en)
DE (1) DE60115712T2 (en)
ES (1) ES2257436T3 (en)
WO (1) WO2002015951A2 (en)

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DE60115712T2 (en) 2006-09-07
EP1365819A2 (en) 2003-12-03
WO2002015951A2 (en) 2002-02-28
US6939377B2 (en) 2005-09-06
AU2001285059A1 (en) 2002-03-04
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US20020065552A1 (en) 2002-05-30
EP1365819B1 (en) 2005-12-07

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