MXPA97003655A - Stent for intraluminal implant and method to implant in a sangui vessel - Google Patents
Stent for intraluminal implant and method to implant in a sangui vesselInfo
- Publication number
- MXPA97003655A MXPA97003655A MXPA/A/1997/003655A MX9703655A MXPA97003655A MX PA97003655 A MXPA97003655 A MX PA97003655A MX 9703655 A MX9703655 A MX 9703655A MX PA97003655 A MXPA97003655 A MX PA97003655A
- Authority
- MX
- Mexico
- Prior art keywords
- wall
- stent
- composite material
- implant
- terminal
- Prior art date
Links
- 239000007943 implant Substances 0.000 title claims abstract description 44
- 239000002131 composite material Substances 0.000 claims abstract description 34
- 210000004204 Blood Vessels Anatomy 0.000 claims abstract description 28
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 26
- 239000000463 material Substances 0.000 claims description 19
- 239000003822 epoxy resin Substances 0.000 claims description 4
- 229920000647 polyepoxide Polymers 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 230000000379 polymerizing Effects 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 2
- 229920001187 thermosetting polymer Polymers 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 1
- 238000002513 implantation Methods 0.000 description 6
- 239000000835 fiber Substances 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- -1 polytetrafluoroethylene Polymers 0.000 description 3
- 229920002635 polyurethane Polymers 0.000 description 3
- 239000004814 polyurethane Substances 0.000 description 3
- 210000004369 Blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 208000007474 Aortic Aneurysm Diseases 0.000 description 1
- 229920000544 Gore-Tex Polymers 0.000 description 1
- 229920002176 Pluracol® Polymers 0.000 description 1
- 239000004698 Polyethylene (PE) Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000011152 fibreglass Substances 0.000 description 1
- 239000011796 hollow space material Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000003014 reinforcing Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920000260 silastic Polymers 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000002210 silicon-based material Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
Abstract
The present invention relates to a stent for intraluminal implant that includes a collapsible tubular member having a first end and a second end. An outer wall and an inner wall extends between the ends. A first terminal wall and a second terminal wall extending between the outer wall and the inner wall. The external, internal walls, the first terminal wall and the second terminal wall form a chamber. A permeable film layer extends between the first terminal wall and the second terminal wall in the chamber. The film layer, the outer wall and the end walls define a space. A composite material is placed in the chamber between the inner wall and the permeable film layer. An orifice is defined in one of the end walls to allow the introduction of a reagent into the defined space. The reagent reacts with the composite material to cause the composite to harden after the stent has been placed in a blood vessel
Description
STENT FOR INTRALUMINAL IMPLANT AND METHOD TO IMPLANT IN A BLOOD VESSEL
BACKGROUND OF THE INVENTION The present invention relates to a stent for intraluminal implant. More specifically, the present invention is directed to a stent for intraluminal implantation that can be implanted in a blood vessel at the site of aortic aneurysms. It can also provide support for damaged blood vessels. Devices for intraluminal support are well known in the art. For example, a stent / graft for intraluminal implant is described in U.S. Patent No. 5, 156,620, which is incorporated herein by reference.
SUMMARY OF THE INVENTION The present invention relates to a stent for intralummal implant. The implant stent includes a collapsible tubular member having a first end and a second end. An outer wall and an inner wall extend between the ends. A first terminal wall and a second terminal wall extend between the outer wall and the inner wall. The external, internal walls, the first terminal wall and the second terminal wall form a chamber. A permeable film layer extends between the first terminal wall and the second terminal wall in the chamber. The film layer, the outer wall and the end walls define a space. A composite material is placed in the chamber between the inner wall and the permeable film layer. In one of the end walls an orifice is defined to allow the introduction of a reagent into the defined space. The reagent reacts with the composite material to cause the composite to harden after the stent for intraluminal implant has been placed inside the blood vessel. The present invention also relates to a method for implanting a stent for intraluminal implant in a blood vessel. The steps are as follows: (a) in a folded catheter a stent for intraluminal implant consisting of a collapsible tubular member having a first end and a second end, an outer wall and an inner wall extending between the ends is placed. , a first terminal wall and a second terminal wall extending between the external wall and an internal wall, the external, internal walls, the first terminal wall and the second terminal wall 'form a chamber, one of the terminal walls defining an orifice , the chamber contains a composite material, the catheter is adjacent to the inner wall; (b) insertion of the stent for intraluminal implantation into a blood vessel by means of the catheter; (c) expanding the catheter to cause the collapsible tubular member to extend into a site in the blood vessel where the stent is to be implanted; (d) the introduction of a reagent through the hole; (e) the reagent is allowed to "react with the composite material to make the composite harden, (f) the catheter is folded, and (g) the catheter is removed from the blood vessel. present invention is to provide a stent for superior intraluminal implant and the implantation method that is effective for repairing blood vessels.An important objective of the present invention is to provide a stent for intraluminal implant that is relatively easy to use. the present invention will be apparent from the review of the drawings and the following detailed description of the invention.
BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a perspective view of the stent for intraluminal implant according to the present invention in a folded state; Figure 2 is a perspective view similar to the view of Figure 1 with a foldable catheter placed in the implant stent; Figure 3 is a sectional view taken along line 3-3 of Figure 2 showing the implant stent placed at the site for "implantation into the blood vessel with an injection device for the introduction of the reagent through the hole in the side wall; Figure 4 is a view of a cut similar to the view of Figure 3 showing the implant stent which is extending by means of the catheter; Figure 5 is a sectional view similar to the view of Figure 4 showing a reagent that is injected into the chamber; and Figure 6 is a view of a section similar to the view of Figure 5 showing the stent implanted in the blood vessel.
DETAILED DESCRIPTION OF THE INVENTION Now in relation to the drawings, the stent for intraluminal implant is indicated with the reference number 10. As shown in figures 1-3, the stent for intraluminal implant 10 includes a collapsible tubular member 12. tubular member 12 includes a first end 14 and a second end 16. An outer wall 18 and an inner wall 20 extend between the ends 14 and 16. The internal wall 20 defines a hollow space. A first terminal wall 22 and a second terminal wall 24 extend between the outer wall 18 and the inner wall 20. As seen in figure 3, the external, internal walls, the first terminal wall and the second terminal wall 18, 20 , 22 and 24, respectively, form a chamber 26. The walls 18, 20, 22 and 24 of the tubular member 12 are formed of a flexible, semi-liquid polymer material such as polytetrafluoroethylene or some other suitable biocompatible material. As shown in Figures 1 and 2, the tubular member 12 in its folded state can be formed in its transverse form as a "cloverleaf". It has been found that this shape allows the stent for intraluminal implant 10 to be easily handled in a blood vessel. However, it should be understood that the tubular member 12 can be formed in a variety of ways.
As seen in Figure 3, a layer of permeable film 30 extends between the first terminal wall 22 and the second terminal wall 24 in the chamber 26. The film layer 30, the outer wall 18, the first terminal wall 22 and the second terminal wall 24 define a variable space 32 in the chamber 30. The permeable film layer 30 can be made from a bevelled, blown or stretched layer of polyethylene, polyurethane, synthetic resin and polymer products, or other suitable polymeric material that has holes or micropores. An example of the material that can be used in the manufacture of the film layer 30 is a microporous polymeric material coated with a material, such as extended polytetrafluoroethylene (ePTFE) available under the tradename GORETEX. "The permeable film layer 30 allows uniform dispersion of the reagent as described below As shown in Figure 3, a composite material 34 is placed in the chamber 26 between the inner wall 20 and the permeable film layer 30. The composite material may consist of a Suitable material that can be hardened, as described below, to implant the stent for implant 10 in a blood vessel 36. An example of a suitable composite material is an epoxy resin, such as that sold under the name "568 B" by Aremco Products, of Ossining, NY Another example of a suitable composite material is a thermosetting polymeric material.Examples of suitable polymeric materials uados are a polyurethane material sold under the trade name PLURACOL P ~ and a silicon material commercially available under the name of SILASTIC®. The composite material 34 can be used with or without reinforcing fibers. If fibers are used, they can be fiberglass fibers of stretched fiber or another fiber of high coefficient, woven in a fabric cover. Still in relation to Figure 3, the stent for intraluminal implant 10 includes a hole 40 between the defined space 32 and the outside of the implant stent. As shown in the embodiment of Figure 3, the orifice 40 includes a one-way valve 42, such as a check valve, for receiving an injection device 44. The one-way valve 42 allows the materials to enter the valve. through the orifice 40 towards the chamber 26 but prevents these materials from coming out through the orifice 40. As shown in Figures 3-6, and as described in detail below in relation to the method of the present invention, it is placed a foldable catheter 50 within the collapsible tubular member 12. The catheter 50 extends to cause the tubular member 12 to extend at the site of implantation within the blood vesselthrough the orifice 40 a reagent 60 is introduced into the defined space 32. The reagent can be a polymerizing agent that can react with a particular composite material 34 to cause the material to harden. The type of reagent used depends on the type of composite material 34 used in the implant stent 10, for example, a reagent commercially available under the name "568 A" reacts with the epoxy resin described above. The polyurethane polymeric material reacts with a catalyst of the salt of a weak acid. The polymeric material of silicon reacts with the catalyst for the hydrosiliation of platinum. It will be very apparent to those skilled in the art that different types of composites and reagents can be used in the present invention depending on the application. The reagent 60 penetrates the permeable film layer 30 and reacts with the composite material 34. The composite material 34 is allowed to harden for a predetermined period. Then, the catheter 50 is folded and removed from the tubular member 12 and the blood vessel 36. The injection device 44 is also removed. The stent for intraluminal implant 10 provides repair and support for the blood vessel at the implantation site.
Still referring to Figures 3-6, the method of the present invention will be described in detail. As shown in Figure 3, a collapsible catheter 50 is placed in the stent for intraluminal implant 10 adjacent to the inner wall 20. The catheter 50 includes an inflated part 52 and a hollow guide wire 54. When the stent for implant 10 is placed in the catheter 50, it can be guided through the blood vessel 36 by the guidewire 54. As seen in Figure 4, the inflated portion 52 of the catheter 50 extends to cause the collapsible tubular member 12 of the graft 10 to extend at the predetermined site 62 in the blood vessel 36 where the graft is to be implanted. As shown in Figure 5, a reagent 60, as described above, is introduced into the defined space 32 through the valve 42 in the orifice 40 by means of an injection device 44. The reagent 60 penetrates the permeable film layer 30 and the reaction begins with the composite material 34, as described above. There is a waiting period for a predetermined time to allow the reagent 60 to react with the composite material to harden it. The inflated portion 52 of the catheter 50 is then folded. Then, the catheter 50 is withdrawn from the blood vessel 36. Also the injection device 44 is removed from the blood vessel 36. The one-way valve 42 prevents the materials from leaving the orifice 40. As shown in Figure 6, the implant stent 10 when implanted provides repair and support for the blood vessel 36 at the repair site 62. Blood can flow through the conduit 64 that is formed with the internal wall 20 of the implant stent. It should be understood that various changes may be made to the present invention, as described herein, without departing from the scope of the appended claims.
Claims (10)
1. A stent for intraluminal implant for use in a blood vessel consisting, in combination, in: a collapsible tubular member having a first end and a second end, an outer wall and an inner wall extending between the ends, a first wall terminal and a second terminal wall extending between the outer wall and the inner wall; the external, internal walls, the first terminal wall and the second terminal wall form a chamber; a permeable film layer extending between the first terminal wall and the second terminal wall in the chamber; this film layer, the outer wall and the terminal walls define a space; a composite material that is placed in the chamber between the inner wall and the permeable film layer; a hole in one of the end walls to introduce a reagent into the defined space; whereby, the implant stent is inserted into a blood vessel, the collapsible tubular member is extended by means of an expandable catheter, a reagent is introduced through the orifice, the reagent travels through the permeable film layer, the The composite material reacts with the reagent causing the material to harden to allow the graft to support the blood vessel.
2. The stent for intraluminal implant of claim no. 1, wherein the collapsible tubular member is composed of a polymeric material.
3. The stent for intraluminal implant of claim no. 1, wherein the permeable film layer is composed of a polymeric material having holes.
4. The stent for intraluminal implant of claim no. 1, wherein the composite material contains an epoxy resin.
5. The stent for intraluminal implant of claim no. 1, wherein the composite material is a thermostable polymeric material.
6. The stent for intraluminal implant of claim no. 1, wherein the reagent is a polymerizing agent that reacts with the composite material to harden the composite material.
7. A method for implanting a stent for intraluminal implant in a blood vessel consisting of the steps: a) the placement of a foldable catheter in a stent for intraluminal implant consisting of a collapsible tubular member having a first end and a second end, an outer wall and an inner wall extending between these ends, a first terminal wall and a second terminal wall extending between the external wall and an internal wall, the internal, external walls, the first terminal wall and the second terminal wall form a chamber, one of the end walls defines a hole, the chamber contains a composite material, the catheter is adjacent to the inner wall; b) the insertion of the stent for intraluminal implant in a blood vessel by means of the catheter; c) the extension of the catheter to make the collapsible tubular member extend to a site in the blood vessel where the stent is to be implanted, d) the introduction of a reagent into the hole, e) the reagent react with the composite material to make the composite harden, f) the catheter is folded, and g) the catheter is removed from the blood vessel
8. The method for implanting the stent for intraluminal implant of claim no. , wherein the composite material consists of an epoxy resin
9. The method for implanting the stent for intraluminal implant of claim 7, wherein the composite material contains a thermoset polymeric material.
10. The method for implanting the stent for intraluminal implant of claim no. 7, wherein the reagent is a polymerizing agent that reacts with the composite material to harden the composite material.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/344,120 US5507770A (en) | 1994-11-23 | 1994-11-23 | Intraluminal grafting stent and method for implanting same in a blood vessel |
| US08344120 | 1994-11-23 | ||
| PCT/US1995/015493 WO1996015744A1 (en) | 1994-11-23 | 1995-11-09 | Intraluminal grafting stent and method for implanting same in a blood vessel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MXPA97003655A true MXPA97003655A (en) | 1997-08-01 |
| MX9703655A MX9703655A (en) | 1997-08-30 |
Family
ID=23349137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9703655A MX9703655A (en) | 1994-11-23 | 1995-11-09 | Intraluminal grafting stent and method for implanting same in a blood vessel. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5507770A (en) |
| EP (1) | EP0793466A1 (en) |
| JP (1) | JPH10509082A (en) |
| AU (1) | AU686039B2 (en) |
| CA (1) | CA2201318A1 (en) |
| MX (1) | MX9703655A (en) |
| NO (1) | NO972187L (en) |
| TW (1) | TW337153U (en) |
| WO (1) | WO1996015744A1 (en) |
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1994
- 1994-11-23 US US08/344,120 patent/US5507770A/en not_active Expired - Lifetime
-
1995
- 1995-11-09 AU AU44112/96A patent/AU686039B2/en not_active Expired - Fee Related
- 1995-11-09 JP JP8517104A patent/JPH10509082A/en active Pending
- 1995-11-09 EP EP95942932A patent/EP0793466A1/en not_active Withdrawn
- 1995-11-09 WO PCT/US1995/015493 patent/WO1996015744A1/en not_active Application Discontinuation
- 1995-11-09 CA CA002201318A patent/CA2201318A1/en not_active Abandoned
- 1995-11-09 MX MX9703655A patent/MX9703655A/en unknown
- 1995-11-20 TW TW086217168U patent/TW337153U/en unknown
-
1997
- 1997-05-13 NO NO972187A patent/NO972187L/en unknown
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