WO2002010376A1 - GENE HUMAIN DU PROMOTEUR DE LA 5α REDUCTASE DE TYPE II ET UTILISATION ASSOCIEE - Google Patents

GENE HUMAIN DU PROMOTEUR DE LA 5α REDUCTASE DE TYPE II ET UTILISATION ASSOCIEE Download PDF

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Publication number
WO2002010376A1
WO2002010376A1 PCT/JP2001/005549 JP0105549W WO0210376A1 WO 2002010376 A1 WO2002010376 A1 WO 2002010376A1 JP 0105549 W JP0105549 W JP 0105549W WO 0210376 A1 WO0210376 A1 WO 0210376A1
Authority
WO
WIPO (PCT)
Prior art keywords
type
human
promoter gene
reductase promoter
reductase
Prior art date
Application number
PCT/JP2001/005549
Other languages
English (en)
Japanese (ja)
Inventor
Jotaro Nakanishi
Toshihiko Hibino
Original Assignee
Shiseido Company, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Company, Ltd. filed Critical Shiseido Company, Ltd.
Priority to EP01943855A priority Critical patent/EP1306432A4/fr
Publication of WO2002010376A1 publication Critical patent/WO2002010376A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne une molécule d'ADN contenant le domaine du gène promoteur du gène humain de la 5α réductase de type II, sa modification, ainsi qu'un procédé permettant de cribler un contrôleur transcriptionnel pour la 5α réductase de type II à l'aide de cette molécule.
PCT/JP2001/005549 2000-07-28 2001-06-28 GENE HUMAIN DU PROMOTEUR DE LA 5α REDUCTASE DE TYPE II ET UTILISATION ASSOCIEE WO2002010376A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP01943855A EP1306432A4 (fr) 2000-07-28 2001-06-28 Gene humain du promoteur de la 5 alpha reductase de type ii et utilisation associee

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000228757A JP2002034575A (ja) 2000-07-28 2000-07-28 ヒトＩＩ型５α−レダクターゼのプロモーター遺伝子およびその用途
JP2000-228757 2000-07-28

Publications (1)

Publication Number Publication Date
WO2002010376A1 true WO2002010376A1 (fr) 2002-02-07

Family

ID=18721991

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2001/005549 WO2002010376A1 (fr) 2000-07-28 2001-06-28 GENE HUMAIN DU PROMOTEUR DE LA 5α REDUCTASE DE TYPE II ET UTILISATION ASSOCIEE

Country Status (4)

Country Link
US (1) US20030157536A1 (fr)
EP (1) EP1306432A4 (fr)
JP (1) JP2002034575A (fr)
WO (1) WO2002010376A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005296003A (ja) * 2004-03-15 2005-10-27 Sumitomo Chemical Co Ltd 三量体Ｇタンパク質αサブユニットＧｍ１のプロモーター及びその利用
WO2005108574A1 (fr) * 2004-03-15 2005-11-17 Sumitomo Chemical Company, Limited PROMOTEUR DE Gm1 ET UTILISATION DE CELUI-CI

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665543A (en) * 1989-07-18 1997-09-09 Oncogene Science, Inc. Method of discovering chemicals capable of functioning as gene expression modulators
JP2004501666A (ja) * 2000-06-30 2004-01-22 エピゲノミクス　アーゲー 薬理ゲノミクスのメチル化状態分析のための方法及び核酸

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ANDERSSON S. ET AL.: "Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism", NATURE, vol. 354, no. 6349, 14 November 1991 (1991-11-14), pages 159 - 161, XP002946695 *
LABRIE F. ET AL.: "Structure of human type II 5 alpha-reductase gene", ENDOCRINOLOGY, vol. 131, no. 3, September 1992 (1992-09-01), pages 1571 - 1573, XP002946693 *
LISTON D.R. ET AL.: "Upstream regulatory sequences required for expression of the trichomonas vaginalis alpha-succinyl CoA synthetase gene", MOL. BIOCHEM. PARASITOL., vol. 104, no. 2, 30 November 1999 (1999-11-30), pages 323 - 329, XP002946696 *
See also references of EP1306432A4 *
WINGENDER E. ET AL.: "TRANSFAC: a database on transcription factors and their DNA binding sites", NUCLEIC ACIDS RES., vol. 24, no. 1, 1 January 1996 (1996-01-01), pages 238 - 241, XP002946694 *

Also Published As

Publication number Publication date
JP2002034575A (ja) 2002-02-05
EP1306432A1 (fr) 2003-05-02
EP1306432A4 (fr) 2004-07-07
US20030157536A1 (en) 2003-08-21

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