WO2001087906A3 - Haplotypes of the stk11 gene - Google Patents

Haplotypes of the stk11 gene Download PDF

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Publication number
WO2001087906A3
WO2001087906A3 PCT/US2001/016045 US0116045W WO0187906A3 WO 2001087906 A3 WO2001087906 A3 WO 2001087906A3 US 0116045 W US0116045 W US 0116045W WO 0187906 A3 WO0187906 A3 WO 0187906A3
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WO
WIPO (PCT)
Prior art keywords
haplotypes
stk11
gene
disclosed
stk11 gene
Prior art date
Application number
PCT/US2001/016045
Other languages
French (fr)
Other versions
WO2001087906A2 (en
Inventor
Karen M Bieglecki
Anne Chew
Julie Y Choi
Krishnan Nandabalan
Elizabeth Ann Sausker
Original Assignee
Genaissance Pharmaceuticals
Karen M Bieglecki
Anne Chew
Julie Y Choi
Krishnan Nandabalan
Elizabeth Ann Sausker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Karen M Bieglecki, Anne Chew, Julie Y Choi, Krishnan Nandabalan, Elizabeth Ann Sausker filed Critical Genaissance Pharmaceuticals
Priority to AU2001264656A priority Critical patent/AU2001264656A1/en
Publication of WO2001087906A2 publication Critical patent/WO2001087906A2/en
Publication of WO2001087906A3 publication Critical patent/WO2001087906A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Novel genetic variants of the Serine/Threonine Kinase 11 (Peutz-Jeghers Syndrome) (STK11) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the STK11 gene. Compositions and methods for haplotyping and/or genotyping the STK11 gene in an individual are also disclosed. Polynucleotides defined by the sequence the haplotypes disclosed herein are also described.
PCT/US2001/016045 2000-05-17 2001-05-17 Haplotypes of the stk11 gene WO2001087906A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001264656A AU2001264656A1 (en) 2001-05-17 2001-05-17 Haplotypes of the stk11 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20469700P 2000-05-17 2000-05-17
US60/204,697 2000-05-17

Publications (2)

Publication Number Publication Date
WO2001087906A2 WO2001087906A2 (en) 2001-11-22
WO2001087906A3 true WO2001087906A3 (en) 2002-05-10

Family

ID=22759044

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016045 WO2001087906A2 (en) 2000-05-17 2001-05-17 Haplotypes of the stk11 gene

Country Status (1)

Country Link
WO (1) WO2001087906A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102994623B (en) * 2011-09-13 2014-07-30 益善生物技术股份有限公司 STK11 gene mutation detection specificity primer and liquid chip thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JENNE D.E. ET AL.: "Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase", NATURE GENETICS, vol. 18, January 1998 (1998-01-01), pages 38 - 43, XP002935456 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102994623B (en) * 2011-09-13 2014-07-30 益善生物技术股份有限公司 STK11 gene mutation detection specificity primer and liquid chip thereof

Also Published As

Publication number Publication date
WO2001087906A2 (en) 2001-11-22

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