WO2001085741A3 - Haplotypes of the sod1 gene - Google Patents

Haplotypes of the sod1 gene Download PDF

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Publication number
WO2001085741A3
WO2001085741A3 PCT/US2001/014772 US0114772W WO0185741A3 WO 2001085741 A3 WO2001085741 A3 WO 2001085741A3 US 0114772 W US0114772 W US 0114772W WO 0185741 A3 WO0185741 A3 WO 0185741A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
disclosed
sod1
gene
sod1 gene
Prior art date
Application number
PCT/US2001/014772
Other languages
French (fr)
Other versions
WO2001085741A2 (en
Inventor
Julie Y Choi
Steven C Bentivegna
Stefanie E Kliem
Beena Koshy
Katie E Parks
Original Assignee
Genaissance Pharmaceuticals
Julie Y Choi
Steven C Bentivegna
Stefanie E Kliem
Beena Koshy
Katie E Parks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Julie Y Choi, Steven C Bentivegna, Stefanie E Kliem, Beena Koshy, Katie E Parks filed Critical Genaissance Pharmaceuticals
Priority to AU2001263000A priority Critical patent/AU2001263000A1/en
Publication of WO2001085741A2 publication Critical patent/WO2001085741A2/en
Publication of WO2001085741A3 publication Critical patent/WO2001085741A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Novel genetic variants of the Superoxide Dismutase 1, Soluble (Amyotrophic Lateral Sclerosis 1 (Adult)) (SOD1) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the SOD1 gene. Compositions and methods for haplotyping and/or genotyping the SOD1 gene in an individual are also disclosed. Polynucleotides defined by the sequence the haplotypes disclosed herein are also described
PCT/US2001/014772 2000-05-05 2001-05-07 Haplotypes of the sod1 gene WO2001085741A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001263000A AU2001263000A1 (en) 2000-05-05 2001-05-07 Haplotypes of the sod1 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20249100P 2000-05-05 2000-05-05
US60/202,491 2000-05-05

Publications (2)

Publication Number Publication Date
WO2001085741A2 WO2001085741A2 (en) 2001-11-15
WO2001085741A3 true WO2001085741A3 (en) 2002-05-23

Family

ID=22750092

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/014772 WO2001085741A2 (en) 2000-05-05 2001-05-07 Haplotypes of the sod1 gene

Country Status (2)

Country Link
AU (1) AU2001263000A1 (en)
WO (1) WO2001085741A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849290A (en) * 1993-02-26 1998-12-15 The General Hospital Corporation Compounds and methods for the diagnosis, treatment and prevention of diseases of cell death

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849290A (en) * 1993-02-26 1998-12-15 The General Hospital Corporation Compounds and methods for the diagnosis, treatment and prevention of diseases of cell death

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KOSTRZEWA M. ET AL.: "Autosomal dominant amytrophic lateral sclerosis: A novel mutation in the Cu/Zn superoxide dismutase-1 gene", HUMAN MOLECULAR GENETICS, vol. 3, no. 12, 1994, pages 2261 - 2262, XP002906606 *

Also Published As

Publication number Publication date
AU2001263000A1 (en) 2001-11-20
WO2001085741A2 (en) 2001-11-15

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