WO2001082814B1 - Apparatus and methods for mapping and ablation in electrophysiology procedures - Google Patents

Apparatus and methods for mapping and ablation in electrophysiology procedures

Info

Publication number
WO2001082814B1
WO2001082814B1 PCT/US2001/013840 US0113840W WO0182814B1 WO 2001082814 B1 WO2001082814 B1 WO 2001082814B1 US 0113840 W US0113840 W US 0113840W WO 0182814 B1 WO0182814 B1 WO 0182814B1
Authority
WO
WIPO (PCT)
Prior art keywords
medical device
conductive member
braided conductive
catheter
coating
Prior art date
Application number
PCT/US2001/013840
Other languages
French (fr)
Other versions
WO2001082814A3 (en
WO2001082814A2 (en
Inventor
Russell F Collins
Gary S Falwell
Eric A Bene
Steven J Burns
Denyse M Collins
Charles A Gibson
Ding Sheng He
Paul E Leclair
Donald F Patterson
Stephen W Sagon
Pierre Jais
Original Assignee
Bard Inc C R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bard Inc C R filed Critical Bard Inc C R
Priority to JP2001579692A priority Critical patent/JP4926359B2/en
Priority to DE60138880T priority patent/DE60138880D1/en
Priority to AT01934942T priority patent/ATE432664T1/en
Priority to EP01934942A priority patent/EP1284670B1/en
Publication of WO2001082814A2 publication Critical patent/WO2001082814A2/en
Publication of WO2001082814A3 publication Critical patent/WO2001082814A3/en
Publication of WO2001082814B1 publication Critical patent/WO2001082814B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00059—Material properties
    • A61B2018/00071—Electrical conductivity
    • A61B2018/00083—Electrical conductivity low, i.e. electrically insulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/0016—Energy applicators arranged in a two- or three dimensional array
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00184—Moving parts
    • A61B2018/00196—Moving parts reciprocating lengthwise
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/00267—Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00791—Temperature
    • A61B2018/00797—Temperature measured by multiple temperature sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00791—Temperature
    • A61B2018/00821—Temperature measured by a thermocouple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/0091—Handpieces of the surgical instrument or device
    • A61B2018/00916—Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device
    • A61B2018/0094—Types of switches or controllers
    • A61B2018/00946—Types of switches or controllers slidable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1497—Electrodes covering only part of the probe circumference

Abstract

An electrophysiology catheter and method of use for mapping and ablation procedures. The catheter includes a braided conductive member at its distal end that can be radially expanded. The catheter can be used in endocardial and epicardial mapping and ablation procedures.

Claims

AMENDED CLAIMS[received by the International Bureau on 07 January 2002 (07.01.02); original claims 1-13 replaced by new claims 1-83 (10 pages)]
1. A medical device for electrophysiology procedures, comprising: a catheter having a braided conductive member at a distal end thereof; a mechanism that expands the braided conductive member from an undeployed to a deployed position; and a shroud that covers at least a portion of the braided conductive member when the braided conductive member is in the deployed position.
2. The medical device of claim 1 , wherein the shroud is a latex material.
3. The medical device of claim 1 , wherein the shroud is composed of an radiofrequency transparent material.
4. The medical device of claim 1, wherein the shroud is comprised of a material resistant to thrombi formation.
5. The medical device of claim 1 , wherein the shroud directs irrigation fluid to a target region.
6. The medical device of claim 1 , wherein the shroud directs contrast fluid to a target region.
7. The medical device of claim 1 , wherein the shroud directs antithrombogenic fluid to a target region.
8. The medical device of claim 5, wherein the target region is a circumferential edge of the braided conductive member.
9. The medical device of claim 6, wherein the target region is a circumferential edge of the braided conductive member. 27
10. The medical device of claim 1 , wherein the shroud covers the entire braided conductive member.
11. The medical device of claim 1 , fαirther comprising a hollow tubular lumen within the catheter.
12. A medical device for electrophysiology procedures, comprising: a catheter having a braided conductive member at a distal end thereof; a mechanism that expands the braided conductive member from an undeployed to a deployed position; and a mechanism that steers the distal end of the catheter.
13. The medical device of claim 12, wherein the mechanism that steers the distal end of the catheter includes a pivot point proximal to the braided conductive member.
14. The medical device of claim 13, wherein the mechanism that steers the distal end of the catheter includes a pivot point distal to the braided conductive member.
15. The medical device of claim 14, wherein the catheter has a first curve in a first plane and a second curve in a second plane at an angle to the first plane.
16. The medical device of claim 12, wherein the braided conductive member is a wire mesh.
17. The medical device of claim 12, further comprising at least one reference electrode disposed on a shaft of the catheter.
18. The medical device of claim 16, wherein the wire mesh includes a number of filaments. 28
19. The medical device of claim 18, wherein the mechanism that expands the braided conductive member expands one or more individual filaments in the wire mesh.
20. The medical device of claim 12, wherein the braided conductive member includes multiple braided conductive members.
21. The medical device of claim 20, wherein the braided conductive members have different expanded diameters.
22. The medical device of claim 20, wherein at least one of the braided conductive members is used for mapping procedures.
23. The medical device of claim 20, wherein at least one of the braided conductive members is used for ablation procedures.
24. The medical device of claim 16, wherein the wire mesh is symmetrical and coaxial about a shaft of the catheter.
25. The medical device of claim 16, wherein the wire mesh is non concentric about a shaft of the catheter.
26. The medical device of claim 16, wherein the wire mesh is asymmetric about a shaft of the catheter.
27. The medical device of claim 16, wherein the wire mesh is preformed to approximate a portion of anatomy.
28. The medical device of claim 12, wherein the braided conductive member comprises a single filament. 29
29. The medical device of claim 18, wherein the filaments have a round cross section.
30. The medical device of claim 18, wherein the filaments have a rectangular cross section.
31. The medical device of claim 18, wherein the filaments includes metallic and non metallic elements.
32. The medical device of claim 18, wherein the filaments are isolated by an insulation coating.
33. The medical device of claim 18, wherein the insulation coating is a polyimide type material.
34. The medical device of claim 18, wherein a portion of the insulation coating is removed from at least one of the filaments.
35. The medical device of claim 34, wherein the insulation coating is removed from the filaments to create at least one sector.
36. The medical device of claim 12, further comprising a hollow tubular lumen within the catheter.
37. A medical device for electrophysiology procedures, comprising: a catheter having a braided conductive member at a distal end thereof; a mechanism that expands the braided conductive member from an undeployed to a deployed position; and a coating material disposed on at least a portion of the braided conductive member. 30
38. The medical device of claim 37, wherein the coating is a lubricious coating.
39. The medical device of claim 37, wherein the coating is an antithrombogenic coating.
40. The medical device of claim 37, wherein the coating is a radioopaque coating.
41. The medical device of claim 37. wherein the coating material is a thermally conductive coating.
42. The medical device of claim 37, further comprising a hollow tubular lumen within the catheter.
43. A medical device for electrophysiology procedures, comprising: a catheter having a braided conductive member at a distal end thereof; a mechanism that expands the braided conductive member from an undeployed to a deployed position; and an irrigation system that delivers an irrigation fluid in proximity to the braided conductive member.
44. The medical device of claim 43, wherein the irrigation system includes at least one tube woven into the braided conductive member.
45. The medical device of claim 44, wherein the at least one tube includes at least one opening for delivering the irrigation fluid.
46. The medical device of claim 43, wherein the irrigation fluid is a contrast fluid. 31
47. The medical device of claim 43, wherein the irrigation fluid is a cooling fluid.
48. The medical device of claim 43, wherein the irrigation fluid is an antithrombogenic fluid.
49. The medical device of claim 43, wherein the braided conductive member includes a number of filaments and at least one of the filaments includes a lumen that delivers the irrigation fluid.
50. A medical device for electrophysiology procedures, comprising: a catheter having a braided conductive member at a distal end thereof; a mechanism that expands the braided conductive member from an undeployed to a deployed position; and a temperature sensing device attached to the braided conductive member.
51. The medical device of claim 50, wherein the temperature sensing device comprises a thermocouple.
52. The medical device of claim 50, further comprising a hollow tubular lumen within the catheter.
53. A guiding mechanism for use with an electrophysiology catheter, comprising: a sheath having a predetermined curve through which the electrophysiology catheter may be passed during introduction to a patient; and a seam disposed along a longitudinal length of the sheath.
54. The guiding mechanism of claim 53, wherein the guiding sheath further includes a hypo tube having a lumen that communicates with an interior of the sheath. 32
55. A method for treating cardiac arrhythmia, comprising the steps of: introducing a catheter into a thoracic cavity of a patient, the catheter having a braided conductive member at a distal end thereof; contacting an exterior wall of a blood vessel or cardiac chamber with the braided conductive member; and applying energy to the exterior wall via the braided conductive member to create a lesion on the exterior wall.
56. The method of claim 55, wherein the braided conductive member is a wire mesh.
57. The method of claim 56, further comprising the step of directing irrigation fluid to a target region.
58. The method of claim 56, further comprising the step of directing contrast fluid to a target region.
59. The method of claim 56, further comprising the step of directing antithrombogenic fluid to a target region.
60. The method of claim 56, further comprising the step of steering the distal end of the catheter.
61. The method of claim 56, further comprising the step of measuring temperature when applying energy to the blood vessel.
62. The method of claim 55, further comprising the step of coating the braided conductive member with a coating material. 33
63. The method of claim 62, wherein the coating step includes using a lubricious coating.
64. The method of claim 62, wherein the coating step includes using an antithrombogenic coating.
65. The method of claim 62, wherein the coating step includes using a radioopaque coating.
66. The method of claim 62, wherein the coating step includes using a thermally conductive coating.
67. The method of claim 62, wherein the coating step includes using an insulation coating.
68. The guiding mechanism of claim 54, wherein the lumen allows introduction of an irrigation fluid.
69. The guiding mechanism of claim 54, wherein the lumen allows introduction of a contrast fluid.
70. The guiding mechanism of claim 54, wherein the lumen allows introduction of an antithrombogenic fluid.
71. The medical device of claim 1, wherein the shroud directs an antithrombogenic fluid to a target region.
72. The medical device of claim 43, wherein the irrigation fluid is an antithrombogenic fluid. 34
73. The medical device of claim 51 , wherein the thermocouple is electrically insulated from the braided conductive member.
74. A medical device for electrophysiology procedures, comprising: a catheter having a braided conductive member at a distal end thereof; a mechanism that expands the braided conductive member from an undeployed to a deployed position; wherein the braided conductive member is constructed of thermocouples.
75. A medical device for electrophysiology procedures, comprising: a braided conductive member having a first end and a second end; a first catheter shaft having an extreme distal end wherein the first end of the braided conductive member is attached to the extreme distal end of the catheter shaft; a second catheter shaft hiving an extreme distal end wherein he second end of the braided conductive member is attached to the extreme distal end of the second catheter shaft and wherein the second catheter shaft is contained within the first catheter shaft; so that in an undeployed position, the braided conductive member is substantially contained within the first catheter shaft; and when the extreme distal end of the first catheter shaft is substantially aligned with the extreme distal end of the second catheter shaft, the braided conductive member is in a deployed position.
76. The medical device of claim 75, wherein the braided conductive member is a wire mesh.
77. The medical device of claim 76, wherein the wire mesh includes a number of filaments.
78. The medical device of claim 77, further comprising a coating material disposed on at least a portion of the wire mesh. 35
79. The medical device of claim 77, further comprising an irrigation system that delivers an irrigation fluid in proximity to the braided conductive member.
80. The medical device of claim 77, further comprising a temperature sensing device attached to the braided conductive member.
81. The medical device of claim 77, further comprising a shroud that covers at least a portion of the braided conductive member when the braided conductive member is in the deployed position.
82. The medical device of claim 75, wherein the braided conductive member further comprises a concentric locating region when the braided conductive member is in the deployed position.
83. The medical device of claim 75, further comprising a hollow tubular lumen within the catheter.
PCT/US2001/013840 2000-05-03 2001-04-27 Apparatus and methods for mapping and ablation in electrophysiology procedures WO2001082814A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001579692A JP4926359B2 (en) 2000-05-03 2001-04-27 Apparatus and method for mapping and cauterization in electrophysiological procedures
DE60138880T DE60138880D1 (en) 2000-05-03 2001-04-27 DEVICE FOR MULTI-DIMENSIONAL PRESENTATION AND ABLATION IN ELECTROPHYSIOLOGICAL PROCEDURES
AT01934942T ATE432664T1 (en) 2000-05-03 2001-04-27 DEVICE FOR MULTI-DIMENSIONAL DISPLAY AND ABLATION IN ELECTROPHYSIOLOGICAL PROCEDURES
EP01934942A EP1284670B1 (en) 2000-05-03 2001-04-27 Apparatus for mapping and ablation in electrophysiology procedures

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US20144500P 2000-05-03 2000-05-03
US60/201,445 2000-05-03
US20448200P 2000-05-16 2000-05-16
US20445700P 2000-05-16 2000-05-16
US60/204,482 2000-05-16
US60/204,457 2000-05-16
US26101501P 2001-01-11 2001-01-11
US60/261,015 2001-01-11

Publications (3)

Publication Number Publication Date
WO2001082814A2 WO2001082814A2 (en) 2001-11-08
WO2001082814A3 WO2001082814A3 (en) 2002-04-04
WO2001082814B1 true WO2001082814B1 (en) 2002-05-02

Family

ID=27498427

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/013840 WO2001082814A2 (en) 2000-05-03 2001-04-27 Apparatus and methods for mapping and ablation in electrophysiology procedures

Country Status (6)

Country Link
US (4) US6837886B2 (en)
EP (3) EP2095784B1 (en)
JP (1) JP4926359B2 (en)
AT (2) ATE427711T1 (en)
DE (2) DE60138880D1 (en)
WO (1) WO2001082814A2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8974445B2 (en) 2009-01-09 2015-03-10 Recor Medical, Inc. Methods and apparatus for treatment of cardiac valve insufficiency
US9138250B2 (en) 2006-04-24 2015-09-22 Ethicon Endo-Surgery, Inc. Medical instrument handle and medical instrument having a handle
US11878095B2 (en) 2018-12-11 2024-01-23 Biosense Webster (Israel) Ltd. Balloon catheter with high articulation
US11918341B2 (en) 2019-12-20 2024-03-05 Biosense Webster (Israel) Ltd. Selective graphical presentation of electrophysiological parameters
US11918383B2 (en) 2020-12-21 2024-03-05 Biosense Webster (Israel) Ltd. Visualizing performance of catheter electrodes
US11950841B2 (en) 2020-09-22 2024-04-09 Biosense Webster (Israel) Ltd. Basket catheter having insulated ablation electrodes and diagnostic electrodes
US11950840B2 (en) 2020-09-22 2024-04-09 Biosense Webster (Israel) Ltd. Basket catheter having insulated ablation electrodes
US11950930B2 (en) 2019-12-12 2024-04-09 Biosense Webster (Israel) Ltd. Multi-dimensional acquisition of bipolar signals from a catheter

Families Citing this family (365)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8728065B2 (en) * 2009-07-02 2014-05-20 St. Jude Medical, Atrial Fibrillation Division, Inc. Apparatus and methods for contactless electrophysiology studies
US8025661B2 (en) * 1994-09-09 2011-09-27 Cardiofocus, Inc. Coaxial catheter instruments for ablation with radiant energy
US7052493B2 (en) * 1996-10-22 2006-05-30 Epicor Medical, Inc. Methods and devices for ablation
US9498604B2 (en) 1997-11-12 2016-11-22 Genesis Technologies Llc Medical device and method
US7426409B2 (en) * 1999-06-25 2008-09-16 Board Of Regents, The University Of Texas System Method and apparatus for detecting vulnerable atherosclerotic plaque
US7935108B2 (en) 1999-07-14 2011-05-03 Cardiofocus, Inc. Deflectable sheath catheters
US20050234437A1 (en) * 1999-07-14 2005-10-20 Cardiofocus, Inc. Deflectable sheath catheters with out-of-plane bent tip
US9033961B2 (en) 1999-07-14 2015-05-19 Cardiofocus, Inc. Cardiac ablation catheters for forming overlapping lesions
US8900219B2 (en) 1999-07-14 2014-12-02 Cardiofocus, Inc. System and method for visualizing tissue during ablation procedures
US20050222558A1 (en) * 1999-07-14 2005-10-06 Cardiofocus, Inc. Methods of cardiac ablation employing a deflectable sheath catheter
US8540704B2 (en) 1999-07-14 2013-09-24 Cardiofocus, Inc. Guided cardiac ablation catheters
US20050234436A1 (en) * 1999-07-14 2005-10-20 Cardiofocus, Inc. Methods of cardiac ablation in the vicinity of the right inferior pulmonary vein
US20060095032A1 (en) 1999-11-16 2006-05-04 Jerome Jackson Methods and systems for determining physiologic characteristics for treatment of the esophagus
EP1229849A1 (en) * 1999-11-16 2002-08-14 Robert A. Ganz System and method of treating abnormal tissue in the human esophagus
US20040215296A1 (en) * 1999-11-16 2004-10-28 Barrx, Inc. System and method for treating abnormal epithelium in an esophagus
US20040215235A1 (en) 1999-11-16 2004-10-28 Barrx, Inc. Methods and systems for determining physiologic characteristics for treatment of the esophagus
ATE427711T1 (en) 2000-05-03 2009-04-15 Bard Inc C R DEVICE FOR IMAGING AND ABLATION IN ELECTROPHYSIOLOGICAL PROCEDURES
US7534242B2 (en) * 2003-02-25 2009-05-19 Artemis Medical, Inc. Tissue separating catheter assembly and method
DE20180138U1 (en) * 2000-06-23 2002-04-04 Salviac Ltd Filter element for embolic protection device
US20040087936A1 (en) * 2000-11-16 2004-05-06 Barrx, Inc. System and method for treating abnormal tissue in an organ having a layered tissue structure
WO2002087437A1 (en) 2001-04-27 2002-11-07 C.R. Bard, Inc. Catheter for three dimensional mapping of electrical activity in blood vessels and ablation procedure
WO2002087456A1 (en) * 2001-05-01 2002-11-07 C.R. Bard, Inc. Method and apparatus for altering conduction properties in the heart and in adjacent vessels
US7727229B2 (en) 2001-05-01 2010-06-01 C.R. Bard, Inc. Method and apparatus for altering conduction properties in the heart and in adjacent vessels
US6585718B2 (en) * 2001-05-02 2003-07-01 Cardiac Pacemakers, Inc. Steerable catheter with shaft support system for resisting axial compressive loads
WO2003089997A2 (en) * 2002-03-15 2003-10-30 C.R. Bard, Inc. Method and apparatus for control of ablation energy and electrogram acquisition through multiple common electrodes in an electrophysiology catheter
US20030176810A1 (en) * 2002-03-15 2003-09-18 Maahs Tracy D. Thermography catheter
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
WO2003094715A1 (en) * 2002-05-07 2003-11-20 Volcano Therapeutics, Inc. Systems and methods for detecting vulnerable plaque
US20040082859A1 (en) 2002-07-01 2004-04-29 Alan Schaer Method and apparatus employing ultrasound energy to treat body sphincters
CA2503258C (en) 2002-08-28 2011-08-16 Heart Leaflet Technologies, Inc. Method and device for treating diseased valve
US7819866B2 (en) * 2003-01-21 2010-10-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation catheter and electrode
US8021359B2 (en) * 2003-02-13 2011-09-20 Coaptus Medical Corporation Transseptal closure of a patent foramen ovale and other cardiac defects
WO2004073505A2 (en) * 2003-02-20 2004-09-02 Prorhythm, Inc. Cardiac ablation devices
US20040220655A1 (en) 2003-03-03 2004-11-04 Sinus Rhythm Technologies, Inc. Electrical conduction block implant device
US7097643B2 (en) * 2003-03-03 2006-08-29 Sinus Rhythm Technologies, Inc. Electrical block positioning devices and methods of use therefor
DE602004011608T2 (en) * 2003-03-28 2009-01-29 C.R. Bard, Inc. Catheter with braided mesh
WO2004110258A2 (en) * 2003-06-10 2004-12-23 Cardiofocus, Inc. Guided cardiac ablation catheters
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
DE202004021943U1 (en) * 2003-09-12 2013-05-13 Vessix Vascular, Inc. Selectable eccentric remodeling and / or ablation of atherosclerotic material
SE526861C2 (en) * 2003-11-17 2005-11-15 Syntach Ag Tissue lesion creation device and a set of devices for the treatment of cardiac arrhythmia disorders
US7150745B2 (en) 2004-01-09 2006-12-19 Barrx Medical, Inc. Devices and methods for treatment of luminal tissue
US7819870B2 (en) * 2005-10-13 2010-10-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Tissue contact and thermal assessment for brush electrodes
US9398967B2 (en) * 2004-03-02 2016-07-26 Syntach Ag Electrical conduction block implant device
US7590454B2 (en) * 2004-03-12 2009-09-15 Boston Scientific Neuromodulation Corporation Modular stimulation lead network
US20050203600A1 (en) * 2004-03-12 2005-09-15 Scimed Life Systems, Inc. Collapsible/expandable tubular electrode leads
US8007495B2 (en) * 2004-03-31 2011-08-30 Biosense Webster, Inc. Catheter for circumferential ablation at or near a pulmonary vein
US20050251116A1 (en) * 2004-05-05 2005-11-10 Minnow Medical, Llc Imaging and eccentric atherosclerotic material laser remodeling and/or ablation catheter
US8412348B2 (en) * 2004-05-06 2013-04-02 Boston Scientific Neuromodulation Corporation Intravascular self-anchoring integrated tubular electrode body
WO2005115226A2 (en) * 2004-05-17 2005-12-08 C.R.Bard, Inc. Mapping and ablation method for the treatment of ventricular tachycardia
WO2005112813A1 (en) 2004-05-17 2005-12-01 C.R. Bard, Inc. Method and apparatus for mapping and7or ablation of cardiac tissue
US7481808B2 (en) * 2004-06-30 2009-01-27 Ethicon, Inc. Flexible electrode device and surgical apparatus equipped with same
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
WO2006063199A2 (en) 2004-12-09 2006-06-15 The Foundry, Inc. Aortic valve repair
US7937160B2 (en) * 2004-12-10 2011-05-03 Boston Scientific Neuromodulation Corporation Methods for delivering cortical electrode leads into patient's head
ES2796627T3 (en) * 2005-01-18 2020-11-27 S D M H Pty Ltd Device for thermal ablation of biological tissue using spherical ablation patterns
US20100312129A1 (en) 2005-01-26 2010-12-09 Schecter Stuart O Cardiovascular haptic handle system
ES2380487T3 (en) * 2005-03-28 2012-05-14 Vessix Vascular, Inc. Characterization of intraluminal electrical tissue and adjusted RF energy for the selective treatment of atheroma and other target tissues
US7618362B2 (en) * 2005-03-28 2009-11-17 Boston Scientific Scimed, Inc. Spacer apparatus for radiation and ablation therapy
US9089423B2 (en) * 2010-05-10 2015-07-28 Hlt, Inc. Stentless support structure
EP3072475B1 (en) 2005-05-27 2018-10-03 HLT, Inc. Stentless support structure
US7967818B2 (en) * 2005-06-10 2011-06-28 Cook Medical Technologies Llc Cautery catheter
US7819868B2 (en) * 2005-06-21 2010-10-26 St. Jude Medical, Atrial Fibrilation Division, Inc. Ablation catheter with fluid distribution structures
US8968379B2 (en) * 2005-09-02 2015-03-03 Medtronic Vascular, Inc. Stent delivery system with multiple evenly spaced pullwires
US8639311B2 (en) 2005-09-08 2014-01-28 Philadelphia Health & Education Corporation Sensing probe comprising multiple, spatially separate, sensing sites
US8038625B2 (en) * 2005-09-15 2011-10-18 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for three-dimensional mapping of electrophysiology information
US8229545B2 (en) 2005-09-15 2012-07-24 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for mapping complex fractionated electrogram information
US20070083192A1 (en) * 2005-10-07 2007-04-12 Eric Welch Apparatus and method for ablation of targeted tissue
US8679109B2 (en) * 2005-10-13 2014-03-25 St. Jude Medical, Atrial Fibrillation Division, Inc. Dynamic contact assessment for electrode catheters
US8672936B2 (en) * 2005-10-13 2014-03-18 St. Jude Medical, Atrial Fibrillation Division, Inc. Systems and methods for assessing tissue contact
US8162935B2 (en) * 2005-10-27 2012-04-24 St. Jude Medical, Atrial Fibrillation Division, Inc. Systems and methods for electrode contact assessment
US7997278B2 (en) * 2005-11-23 2011-08-16 Barrx Medical, Inc. Precision ablating method
US7959627B2 (en) 2005-11-23 2011-06-14 Barrx Medical, Inc. Precision ablating device
US8702694B2 (en) 2005-11-23 2014-04-22 Covidien Lp Auto-aligning ablating device and method of use
WO2007079268A2 (en) * 2005-12-30 2007-07-12 C.R. Bard, Inc. Methods and apparatus for ablation of cardiac tissue
DE102006001849A1 (en) * 2006-01-13 2007-07-19 Siemens Ag Mapping catheter for determining image data from the heart comprises a thermal sensor for determining temperature data on the tip of the catheter in the distal region of the catheter
US7749249B2 (en) 2006-02-21 2010-07-06 Kardium Inc. Method and device for closing holes in tissue
US9480552B2 (en) 2006-04-26 2016-11-01 The Cleveland Clinic Foundation Apparatus and method for treating cardiovascular diseases
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US7597661B2 (en) * 2006-05-11 2009-10-06 Ethicon Endo-Surgery, Inc. Medical instrument having a catheter and method for using a catheter
US7988639B2 (en) * 2006-05-17 2011-08-02 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for complex geometry modeling of anatomy using multiple surface models
US7774051B2 (en) * 2006-05-17 2010-08-10 St. Jude Medical, Atrial Fibrillation Division, Inc. System and method for mapping electrophysiology information onto complex geometry
US20070270688A1 (en) 2006-05-19 2007-11-22 Daniel Gelbart Automatic atherectomy system
EP2021846B1 (en) 2006-05-19 2017-05-03 Koninklijke Philips N.V. Ablation device with optimized input power profile
US7729752B2 (en) 2006-06-13 2010-06-01 Rhythmia Medical, Inc. Non-contact cardiac mapping, including resolution map
US7515954B2 (en) 2006-06-13 2009-04-07 Rhythmia Medical, Inc. Non-contact cardiac mapping, including moving catheter and multi-beat integration
US10028783B2 (en) 2006-06-28 2018-07-24 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US11389232B2 (en) 2006-06-28 2022-07-19 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US9119633B2 (en) 2006-06-28 2015-09-01 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US8920411B2 (en) 2006-06-28 2014-12-30 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
EP2038002A4 (en) * 2006-06-28 2010-12-29 Bard Inc C R Methods and apparatus for assessing and improving electrode contact with cardiac tissue
US7837610B2 (en) 2006-08-02 2010-11-23 Kardium Inc. System for improving diastolic dysfunction
FR2905591B1 (en) * 2006-09-11 2009-04-17 Raouf Ayman Abdul PROBE FOR ELECTROCOAGULATION OCCLUSION OF BLOOD VESSEL AND OCCLUSION DEVICE INCORPORATING SUCH PROBE
US10022181B2 (en) * 2006-09-27 2018-07-17 Medtronic Cryocath Lp Thermocouple mesh system for a medical device
US20080082165A1 (en) * 2006-09-28 2008-04-03 Heart Leaflet Technologies, Inc. Delivery Tool For Percutaneous Delivery Of A Prosthesis
ES2407329T3 (en) 2006-10-18 2013-06-12 Vessix Vascular, Inc. System to induce desirable temperature effects on body tissue
EP2455035B1 (en) 2006-10-18 2015-11-25 Vessix Vascular, Inc. Inducing desirable temperature effects on body tissue
EP2954868A1 (en) 2006-10-18 2015-12-16 Vessix Vascular, Inc. Tuned rf energy and electrical tissue characterization for selective treatment of target tissues
EP1982655B2 (en) * 2007-04-16 2022-12-07 Occlutech Holding AG Occluder to seal an atrial appendage and method of manufacture thereof
US8226648B2 (en) 2007-12-31 2012-07-24 St. Jude Medical, Atrial Fibrillation Division, Inc. Pressure-sensitive flexible polymer bipolar electrode
US10085798B2 (en) 2006-12-29 2018-10-02 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation electrode with tactile sensor
US10166066B2 (en) 2007-03-13 2019-01-01 University Of Virginia Patent Foundation Epicardial ablation catheter and method of use
WO2008118737A1 (en) 2007-03-22 2008-10-02 University Of Virginia Patent Foundation Electrode catheter for ablation purposes and related method thereof
BRPI0809127B8 (en) 2007-03-19 2021-06-22 Univ Virginia Patent Foundation devices and methods for accessing one or more locations and detecting pressure at one or more locations
US9468396B2 (en) 2007-03-19 2016-10-18 University Of Virginia Patent Foundation Systems and methods for determining location of an access needle in a subject
US11058354B2 (en) 2007-03-19 2021-07-13 University Of Virginia Patent Foundation Access needle with direct visualization and related methods
US20080234673A1 (en) * 2007-03-20 2008-09-25 Arthrocare Corporation Multi-electrode instruments
WO2008124603A1 (en) 2007-04-05 2008-10-16 Nmt Medical, Inc. Septal closure device with centering mechanism
US8496653B2 (en) 2007-04-23 2013-07-30 Boston Scientific Scimed, Inc. Thrombus removal
WO2008137757A1 (en) 2007-05-04 2008-11-13 Barrx Medical, Inc. Method and apparatus for gastrointestinal tract ablation for treatment of obesity
US8784338B2 (en) 2007-06-22 2014-07-22 Covidien Lp Electrical means to normalize ablational energy transmission to a luminal tissue surface of varying size
KR101513926B1 (en) * 2007-07-06 2015-04-21 코비디엔 엘피 Ablation in the gastrointestinal tract to achieve hemostasis and eradicate lesions with a propensity for bleeding
US8251992B2 (en) 2007-07-06 2012-08-28 Tyco Healthcare Group Lp Method and apparatus for gastrointestinal tract ablation to achieve loss of persistent and/or recurrent excess body weight following a weight-loss operation
US20090012518A1 (en) * 2007-07-06 2009-01-08 Utley David S Method and Apparatus for Ablation of Benign, Pre-Cancerous and Early Cancerous Lesions That Originate Within the Epithelium and are Limited to the Mucosal Layer of the Gastrointestinal Tract
US20100049189A1 (en) * 2007-07-22 2010-02-25 Duane Dickens Device and method for treating annular organ structure
US8273012B2 (en) 2007-07-30 2012-09-25 Tyco Healthcare Group, Lp Cleaning device and methods
US8646460B2 (en) 2007-07-30 2014-02-11 Covidien Lp Cleaning device and methods
ATE552792T1 (en) * 2007-08-10 2012-04-15 Beijing Amsino Medical Co Ltd ELECTROPHYSIOLOGICAL ABLATION DEVICE
EP2205309A4 (en) * 2007-10-05 2011-05-11 Coaptus Medical Corp Systems and methods for transeptal cardiac procedures
US20100241185A1 (en) 2007-11-09 2010-09-23 University Of Virginia Patent Foundation Steerable epicardial pacing catheter system placed via the subxiphoid process
US8906011B2 (en) 2007-11-16 2014-12-09 Kardium Inc. Medical device for use in bodily lumens, for example an atrium
CN101888813B (en) 2007-12-06 2012-12-12 皇家飞利浦电子股份有限公司 Apparatus, a method and a computer program for applying energy to an object
WO2009072039A2 (en) * 2007-12-06 2009-06-11 Koninklijke Philips Electronics N.V. Apparatus, method and computer program for applying energy to an object
US8103327B2 (en) 2007-12-28 2012-01-24 Rhythmia Medical, Inc. Cardiac mapping catheter
US8585696B2 (en) * 2007-12-28 2013-11-19 Boston Scientific Scimed, Inc. Electrosurgical probe having conductive outer surface to initiate ablation between electrode
US20090171339A1 (en) * 2007-12-28 2009-07-02 Boston Scientific Scimed, Inc. Electrosurgical probe having current enhancing protrusions
WO2009094588A2 (en) * 2008-01-24 2009-07-30 Coherex Medical, Inc. Systems and methods for reduction of atrial fibrillation
US8489172B2 (en) 2008-01-25 2013-07-16 Kardium Inc. Liposuction system
US8353902B2 (en) 2008-01-31 2013-01-15 Vivant Medical, Inc. Articulating ablation device and method
US20130165967A1 (en) 2008-03-07 2013-06-27 W.L. Gore & Associates, Inc. Heart occlusion devices
US9011425B2 (en) * 2008-03-12 2015-04-21 Afreeze Gmbh Ablation system
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
EP2280741A4 (en) 2008-04-29 2012-06-13 Virginia Tech Intell Prop Irreversible electroporation to create tissue scaffolds
US10448989B2 (en) 2009-04-09 2019-10-22 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US20090287304A1 (en) 2008-05-13 2009-11-19 Kardium Inc. Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve
US9050069B2 (en) * 2008-05-16 2015-06-09 Medtronic Cryocath Lp Thermocouple-controlled catheter cooling system
US20090318914A1 (en) * 2008-06-18 2009-12-24 Utley David S System and method for ablational treatment of uterine cervical neoplasia
US8888792B2 (en) 2008-07-14 2014-11-18 Ethicon Endo-Surgery, Inc. Tissue apposition clip application devices and methods
WO2010027798A2 (en) * 2008-08-26 2010-03-11 Northwestern University Ablation devices and related methods thereof
CA2737785A1 (en) * 2008-09-22 2010-03-25 Minnow Medical, Inc. Inducing desirable temperature effects on body tissue using alternate energy sources
US10064697B2 (en) 2008-10-06 2018-09-04 Santa Anna Tech Llc Vapor based ablation system for treating various indications
US9561066B2 (en) 2008-10-06 2017-02-07 Virender K. Sharma Method and apparatus for tissue ablation
US10695126B2 (en) 2008-10-06 2020-06-30 Santa Anna Tech Llc Catheter with a double balloon structure to generate and apply a heated ablative zone to tissue
EP2341859B1 (en) 2008-10-06 2017-04-05 Virender K. Sharma Apparatus for tissue ablation
US9561068B2 (en) 2008-10-06 2017-02-07 Virender K. Sharma Method and apparatus for tissue ablation
WO2010042686A1 (en) 2008-10-09 2010-04-15 Sharma Virender K Method and apparatus for stimulating the vascular system
US10603489B2 (en) 2008-10-09 2020-03-31 Virender K. Sharma Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage
US8167876B2 (en) 2008-10-27 2012-05-01 Rhythmia Medical, Inc. Tracking system using field mapping
WO2010056745A1 (en) 2008-11-17 2010-05-20 Minnow Medical, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US9352174B2 (en) * 2008-12-30 2016-05-31 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation system with blood leakage minimization and tissue protective capabilities
US9629678B2 (en) * 2008-12-30 2017-04-25 St. Jude Medical, Atrial Fibrillation Division, Inc. Controlled irrigated catheter ablation systems and methods thereof
US8712550B2 (en) 2008-12-30 2014-04-29 Biosense Webster, Inc. Catheter with multiple electrode assemblies for use at or near tubular regions of the heart
US8372033B2 (en) * 2008-12-31 2013-02-12 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter having proximal heat sensitive deflection mechanism and related methods of use and manufacturing
JP2010162300A (en) * 2009-01-14 2010-07-29 Vivant Medical Inc Articulating ablation device and method
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US8551096B2 (en) 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
US8903488B2 (en) 2009-05-28 2014-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9226791B2 (en) 2012-03-12 2016-01-05 Advanced Cardiac Therapeutics, Inc. Systems for temperature-controlled ablation using radiometric feedback
US9277961B2 (en) 2009-06-12 2016-03-08 Advanced Cardiac Therapeutics, Inc. Systems and methods of radiometrically determining a hot-spot temperature of tissue being treated
US8954161B2 (en) 2012-06-01 2015-02-10 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature and detecting tissue contact prior to and during tissue ablation
US8926605B2 (en) 2012-02-07 2015-01-06 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature during tissue ablation
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US20120029556A1 (en) 2009-06-22 2012-02-02 Masters Steven J Sealing device and delivery system
US8956389B2 (en) 2009-06-22 2015-02-17 W. L. Gore & Associates, Inc. Sealing device and delivery system
CA2766640C (en) 2009-06-30 2016-01-05 Boston Scientific Scimed, Inc. Map and ablate open irrigated hybrid catheter
WO2011008681A1 (en) * 2009-07-13 2011-01-20 Boston Scientific Scimed, Inc. Open-irrigated ablation catheter with turbulent flow
US20110022041A1 (en) * 2009-07-24 2011-01-27 Frank Ingle Systems and methods for titrating rf ablation
US8442613B2 (en) * 2009-07-29 2013-05-14 Boston Scientific Scimed, Inc Mapping probe assembly with skived tube body frame
US9642534B2 (en) 2009-09-11 2017-05-09 University Of Virginia Patent Foundation Systems and methods for determining location of an access needle in a subject
EP2482749B1 (en) 2009-10-01 2017-08-30 Kardium Inc. Kit for constricting tissue or a bodily orifice, for example, a mitral valve
WO2011041629A2 (en) 2009-10-02 2011-04-07 Cardiofocus, Inc. Cardiac ablation system with pulsed aiming light
WO2011044248A2 (en) 2009-10-06 2011-04-14 Cardiofocus, Inc. Cardiac ablation image analysis system and process
KR101673574B1 (en) 2009-10-30 2016-11-07 레코 메디컬, 인코포레이티드 Method and apparatus for treatment of hypertension through percutaneous ultrasound renal denervation
US9028483B2 (en) * 2009-12-18 2015-05-12 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
EP2537149B1 (en) 2010-02-18 2017-10-25 University Of Virginia Patent Foundation System, method, and computer program product for simulating epicardial electrophysiology procedures
US8425455B2 (en) 2010-03-30 2013-04-23 Angiodynamics, Inc. Bronchial catheter and method of use
EP2555699B1 (en) 2010-04-09 2019-04-03 Vessix Vascular, Inc. Power generating and control apparatus for the treatment of tissue
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
JP5760079B2 (en) * 2010-04-14 2015-08-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Device for delivering denervation therapy to the renal arteries
US8694074B2 (en) 2010-05-11 2014-04-08 Rhythmia Medical, Inc. Electrode displacement determination
US10335577B2 (en) * 2010-05-19 2019-07-02 Nfinium Vascular Technologies, Llc Augmented delivery catheter and method
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9561094B2 (en) * 2010-07-23 2017-02-07 Nfinium Vascular Technologies, Llc Devices and methods for treating venous diseases
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US8934956B2 (en) * 2010-08-31 2015-01-13 Interventional Autonomics Corporation Intravascular electrodes and anchoring devices for transvascular stimulation
EP2616005A1 (en) 2010-09-15 2013-07-24 The United States Of America As Represented By The Secretary, National Institutes Of Health Devices for transcatheter cerclage annuloplasty
US20120078078A1 (en) 2010-09-24 2012-03-29 C.R. Bard Means for securing a catheter into a vessel
US8940002B2 (en) 2010-09-30 2015-01-27 Kardium Inc. Tissue anchor system
WO2012051433A2 (en) 2010-10-13 2012-04-19 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
TW201221165A (en) * 2010-10-20 2012-06-01 Medtronic Ardian Luxembourg Catheter apparatuses having expandable mesh structures for renal neuromodulation and associated systems and methods
US9084610B2 (en) 2010-10-21 2015-07-21 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
US10517667B2 (en) 2014-05-16 2019-12-31 Biosense Webster (Israel) Ltd. Catheter tip with microelectrodes
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US9452016B2 (en) 2011-01-21 2016-09-27 Kardium Inc. Catheter system
CA2764494A1 (en) 2011-01-21 2012-07-21 Kardium Inc. Enhanced medical device for use in bodily cavities, for example an atrium
US9480525B2 (en) 2011-01-21 2016-11-01 Kardium, Inc. High-density electrode-based medical device system
US11259867B2 (en) 2011-01-21 2022-03-01 Kardium Inc. High-density electrode-based medical device system
US10278774B2 (en) 2011-03-18 2019-05-07 Covidien Lp Selectively expandable operative element support structure and methods of use
US9072511B2 (en) 2011-03-25 2015-07-07 Kardium Inc. Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve
EP2693969B1 (en) * 2011-04-08 2016-02-03 Covidien LP Microwave device for treating tissue
US8942828B1 (en) * 2011-04-13 2015-01-27 Stuart Schecter, LLC Minimally invasive cardiovascular support system with true haptic coupling
AU2012246723C9 (en) 2011-04-22 2014-08-28 Topera, Inc. Basket style cardiac mapping catheter having an atraumatic basket tip for detection of cardiac rhythm disorders
EP2734259B1 (en) 2011-07-20 2016-11-23 Boston Scientific Scimed, Inc. Percutaneous device to visualize, target and ablate nerves
US9186209B2 (en) 2011-07-22 2015-11-17 Boston Scientific Scimed, Inc. Nerve modulation system having helical guide
US9387031B2 (en) 2011-07-29 2016-07-12 Medtronic Ablation Frontiers Llc Mesh-overlayed ablation and mapping device
US9770232B2 (en) * 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
EP2796103B1 (en) 2011-08-25 2017-02-22 Covidien LP Systems and devices for treatment of luminal tissue
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
WO2013070724A1 (en) * 2011-11-08 2013-05-16 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
WO2013090848A1 (en) 2011-12-15 2013-06-20 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and methods for treating pulmonary hypertension
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
WO2013096920A1 (en) 2011-12-23 2013-06-27 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2013101452A1 (en) 2011-12-28 2013-07-04 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
USD777926S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
USD777925S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
US10576278B2 (en) 2012-02-21 2020-03-03 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
US8706234B2 (en) 2012-02-21 2014-04-22 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat anal dysfunction
US9782583B2 (en) 2012-02-21 2017-10-10 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
WO2013169927A1 (en) 2012-05-08 2013-11-14 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US9427255B2 (en) 2012-05-14 2016-08-30 Ethicon Endo-Surgery, Inc. Apparatus for introducing a steerable camera assembly into a patient
US9017320B2 (en) 2012-05-21 2015-04-28 Kardium, Inc. Systems and methods for activating transducers
US10827977B2 (en) 2012-05-21 2020-11-10 Kardium Inc. Systems and methods for activating transducers
US9198592B2 (en) 2012-05-21 2015-12-01 Kardium Inc. Systems and methods for activating transducers
US10013082B2 (en) 2012-06-05 2018-07-03 Stuart Schecter, LLC Operating system with haptic interface for minimally invasive, hand-held surgical instrument
CN103584914B (en) * 2012-08-17 2015-11-25 王涛 Reticular radiofrequency ablation electrode
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
US9113911B2 (en) 2012-09-06 2015-08-25 Medtronic Ablation Frontiers Llc Ablation device and method for electroporating tissue cells
US8612022B1 (en) 2012-09-13 2013-12-17 Invatec S.P.A. Neuromodulation catheters and associated systems and methods
WO2014043687A2 (en) 2012-09-17 2014-03-20 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
WO2014047411A1 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
WO2014047454A2 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
US9504476B2 (en) * 2012-10-01 2016-11-29 Microvention, Inc. Catheter markers
US10835305B2 (en) 2012-10-10 2020-11-17 Boston Scientific Scimed, Inc. Renal nerve modulation devices and methods
US9827036B2 (en) 2012-11-13 2017-11-28 Pulnovo Medical (Wuxi) Co., Ltd. Multi-pole synchronous pulmonary artery radiofrequency ablation catheter
US11241267B2 (en) 2012-11-13 2022-02-08 Pulnovo Medical (Wuxi) Co., Ltd Multi-pole synchronous pulmonary artery radiofrequency ablation catheter
CN102908191A (en) 2012-11-13 2013-02-06 陈绍良 Multipolar synchronous pulmonary artery radiofrequency ablation catheter
US10260181B2 (en) 2013-01-14 2019-04-16 Lake Region Medical, Inc. Directional mesh and associated systems
EP2945556A4 (en) 2013-01-17 2016-08-31 Virender K Sharma Method and apparatus for tissue ablation
US10828019B2 (en) 2013-01-18 2020-11-10 W.L. Gore & Associates, Inc. Sealing device and delivery system
US9888956B2 (en) 2013-01-22 2018-02-13 Angiodynamics, Inc. Integrated pump and generator device and method of use
CN205215353U (en) * 2013-02-07 2016-05-11 上海魅丽纬叶医疗科技有限公司 Radio frequency melts system and radio frequency melts equipment thereof
EP2769695A1 (en) * 2013-02-20 2014-08-27 Cook Medical Technologies LLC Expandable mesh platform for large area ablation
US10195467B2 (en) 2013-02-21 2019-02-05 Boston Scientific Scimed, Inc. Ablation catheter system with wireless radio frequency temperature sensor
US10028764B2 (en) 2013-02-21 2018-07-24 Boston Scientific Scimed, Inc. Ablation catheter with wireless temperature sensor
CN103169537B (en) * 2013-02-26 2015-09-09 上海安通医疗科技有限公司 The netted radio frequency ablation catheter of a kind of multipole
US10098527B2 (en) 2013-02-27 2018-10-16 Ethidcon Endo-Surgery, Inc. System for performing a minimally invasive surgical procedure
US9474486B2 (en) * 2013-03-08 2016-10-25 St. Jude Medical, Atrial Fibrillation Division, Inc. Basket for a multi-electrode array catheter
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
CN106178294B (en) 2013-03-14 2018-11-20 瑞蔻医药有限公司 A kind of endovascular ablation system based on ultrasound
AU2014237950B2 (en) 2013-03-15 2017-04-13 Boston Scientific Scimed, Inc. Control unit for use with electrode pads and a method for estimating an electrical leakage
EP3231394A1 (en) 2013-03-15 2017-10-18 Hlt, Inc. Low-profile prosthetic valve structure
EP2967734B1 (en) 2013-03-15 2019-05-15 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
US20150066010A1 (en) * 2013-05-24 2015-03-05 Cook Medical Technologies Llc Expandable mesh platform for cardiac ablation
EP3010437A1 (en) 2013-06-21 2016-04-27 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US10022182B2 (en) 2013-06-21 2018-07-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation having rotatable shafts
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
US9833283B2 (en) 2013-07-01 2017-12-05 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
EP3019106A1 (en) 2013-07-11 2016-05-18 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
CN105377169B (en) 2013-07-11 2019-04-19 波士顿科学国际有限公司 Device and method for neuromodulation
CN105682594B (en) 2013-07-19 2018-06-22 波士顿科学国际有限公司 Helical bipolar electrodes renal denervation dominates air bag
CN105392435B (en) 2013-07-22 2018-11-09 波士顿科学国际有限公司 Renal nerve ablation catheter with twisting sacculus
WO2015013205A1 (en) 2013-07-22 2015-01-29 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US20150032103A1 (en) * 2013-07-29 2015-01-29 Cook Medical Technologies Llc Bipolar Ablation Device
US10722300B2 (en) 2013-08-22 2020-07-28 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
WO2015035047A1 (en) 2013-09-04 2015-03-12 Boston Scientific Scimed, Inc. Radio frequency (rf) balloon catheter having flushing and cooling capability
US20150073515A1 (en) 2013-09-09 2015-03-12 Medtronic Ardian Luxembourg S.a.r.I. Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods
US10952790B2 (en) 2013-09-13 2021-03-23 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
CN105592778B (en) 2013-10-14 2019-07-23 波士顿科学医学有限公司 High-resolution cardiac mapping electrod-array conduit
JP6259098B2 (en) 2013-10-15 2018-01-10 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Medical device and method for manufacturing the medical device
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
JP6259099B2 (en) 2013-10-18 2018-01-10 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Balloon catheter comprising a conductive wire with flexibility, and related uses and manufacturing methods
JP2016534842A (en) 2013-10-25 2016-11-10 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Embedded thermocouples in denervation flex circuits
EP3091922B1 (en) 2014-01-06 2018-10-17 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
WO2015119890A1 (en) 2014-02-04 2015-08-13 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US10028785B2 (en) 2014-02-06 2018-07-24 Acublate, Inc. Apparatus and method for self-guided ablation
US9579149B2 (en) 2014-03-13 2017-02-28 Medtronic Ardian Luxembourg S.A.R.L. Low profile catheter assemblies and associated systems and methods
US9999463B2 (en) 2014-04-14 2018-06-19 NeuroMedic, Inc. Monitoring nerve activity
US20170027460A1 (en) * 2015-07-29 2017-02-02 NeuroMedic, Inc. Intraluminal microneurography probe
WO2015167929A1 (en) 2014-04-28 2015-11-05 Cardiofocus, Inc. System and method for visualizing tissue with an icg dye composition during ablation procedures
AU2015259303B2 (en) 2014-05-12 2021-10-28 Arena, Christopher B. Selective modulation of intracellular effects of cells using pulsed electric fields
EP3151904A4 (en) 2014-06-04 2018-02-14 Nfinium Vascular Technologies, LLC Low radial force vascular device and method of occlusion
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
US10722184B2 (en) 2014-11-17 2020-07-28 Kardium Inc. Systems and methods for selecting, activating, or selecting and activating transducers
US10368936B2 (en) 2014-11-17 2019-08-06 Kardium Inc. Systems and methods for selecting, activating, or selecting and activating transducers
EP3220843B1 (en) 2014-11-19 2020-01-01 EPiX Therapeutics, Inc. Ablation devices and methods of using a high-resolution electrode assembly
JP6673598B2 (en) 2014-11-19 2020-03-25 エピックス セラピューティクス，インコーポレイテッド High resolution mapping of tissue with pacing
CA2967829A1 (en) 2014-11-19 2016-05-26 Advanced Cardiac Therapeutics, Inc. Systems and methods for high-resolution mapping of tissue
EP3226744A4 (en) 2014-12-03 2018-08-08 Cardiofocus, Inc. System and method for visual confirmation of pulmonary vein isolation during ablation procedures
WO2016100325A1 (en) 2014-12-15 2016-06-23 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
JP6499887B2 (en) * 2015-03-13 2019-04-10 テルモ株式会社 Medical device
US9636164B2 (en) 2015-03-25 2017-05-02 Advanced Cardiac Therapeutics, Inc. Contact sensing systems and methods
US20170071543A1 (en) * 2015-09-14 2017-03-16 Biosense Webster (Israel) Ltd. Convertible basket catheter
WO2017117582A1 (en) * 2015-12-30 2017-07-06 Schuler Scientific Solutions, Llc Tissue mapping and treatment
US11344365B2 (en) 2016-01-05 2022-05-31 Cardiofocus, Inc. Ablation system with automated sweeping ablation energy element
US10350423B2 (en) 2016-02-04 2019-07-16 Cardiac Pacemakers, Inc. Delivery system with force sensor for leadless cardiac device
AU2017235224A1 (en) 2016-03-15 2018-11-08 Epix Therapeutics, Inc. Improved devices, systems and methods for irrigated ablation
US10932850B2 (en) 2016-05-02 2021-03-02 Affera, Inc. Lesion formation
US11007059B2 (en) 2016-05-06 2021-05-18 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US11039923B2 (en) 2016-05-06 2021-06-22 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US11331140B2 (en) 2016-05-19 2022-05-17 Aqua Heart, Inc. Heated vapor ablation systems and methods for treating cardiac conditions
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
USD851245S1 (en) 2017-04-14 2019-06-11 Cardiofocus, Inc. Compliant balloon
WO2018200865A1 (en) 2017-04-27 2018-11-01 Epix Therapeutics, Inc. Determining nature of contact between catheter tip and tissue
US11647935B2 (en) 2017-07-24 2023-05-16 St. Jude Medical, Cardiology Division, Inc. Masked ring electrodes
EP3672532B1 (en) 2017-08-26 2022-08-03 Transmural Systems LLC Implantable cardiac pacing system
WO2019071269A2 (en) 2017-10-06 2019-04-11 Powell Charles Lee System and method to treat obstructive sleep apnea
US10966748B2 (en) * 2017-11-27 2021-04-06 Rafic Saleh Endoscopic snare
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
DE102017130526A1 (en) * 2017-12-19 2019-06-19 Medizinische Hochschule Hannover Needle-shaped applicator
WO2019140451A1 (en) 2018-01-15 2019-07-18 Cardiofocus, Inc. Ablation system with automated ablation energy element
US11478298B2 (en) 2018-01-24 2022-10-25 Medtronic Ardian Luxembourg S.A.R.L. Controlled irrigation for neuromodulation systems and associated methods
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US11246644B2 (en) 2018-04-05 2022-02-15 Covidien Lp Surface ablation using bipolar RF electrode
CA3102080A1 (en) 2018-06-01 2019-12-05 Santa Anna Tech Llc Multi-stage vapor-based ablation treatment methods and vapor generation and delivery systems
US11850051B2 (en) 2019-04-30 2023-12-26 Biosense Webster (Israel) Ltd. Mapping grid with high density electrode array
US11950835B2 (en) 2019-06-28 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
US20210196926A1 (en) * 2019-12-31 2021-07-01 Biosense Webster (Israel) Ltd. System and methods of using a catheter with an anchoring mechanism
US20220087739A1 (en) * 2020-09-18 2022-03-24 Acclarent, Inc. Ent instrument with expandable ablation feature
JP2024509644A (en) 2021-04-07 2024-03-04 ビーティーエル メディカル デベロップメント エー．エス． Pulsed field ablation device and method
EP4108197A1 (en) 2021-06-24 2022-12-28 Gradient Denervation Technologies Systems for treating tissue
IL309432A (en) 2021-07-06 2024-02-01 Btl Medical Dev A S Pulsed field ablation device and method
WO2023018741A1 (en) * 2021-08-10 2023-02-16 Physcade, Inc. Treatment system with sensing and ablation catheter for treatment of heart rhythm disorders
US20230149021A1 (en) * 2021-11-18 2023-05-18 Covidien Lp Retrieval of material from corporeal lumens
CN117257438B (en) * 2023-11-21 2024-02-06 梅奥心磁(杭州)医疗科技有限公司 Dual-energy mapping ablation catheter

Family Cites Families (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US554108A (en) * 1896-02-04 cahill
US6014590A (en) 1974-03-04 2000-01-11 Ep Technologies, Inc. Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions
US3996938A (en) 1975-07-10 1976-12-14 Clark Iii William T Expanding mesh catheter
DE2821048C2 (en) * 1978-05-13 1980-07-17 Willy Ruesch Gmbh & Co Kg, 7053 Kernen Medical instrument
WO1986002331A1 (en) * 1984-10-12 1986-04-24 Arnold Clair Virgil Holmberg Propellors for watercraft
US4660571A (en) 1985-07-18 1987-04-28 Cordis Corporation Percutaneous lead having radially adjustable electrode
US4699147A (en) 1985-09-25 1987-10-13 Cordis Corporation Intraventricular multielectrode cardial mapping probe and method for using same
US4664120A (en) 1986-01-22 1987-05-12 Cordis Corporation Adjustable isodiametric atrial-ventricular pervenous lead
US4709698A (en) * 1986-05-14 1987-12-01 Thomas J. Fogarty Heatable dilation catheter
US5231995A (en) 1986-11-14 1993-08-03 Desai Jawahar M Method for catheter mapping and ablation
US4940064A (en) 1986-11-14 1990-07-10 Desai Jawahar M Catheter for mapping and ablation and method therefor
US5215103A (en) 1986-11-14 1993-06-01 Desai Jawahar M Catheter for mapping and ablation and method therefor
US5365926A (en) 1986-11-14 1994-11-22 Desai Jawahar M Catheter for mapping and ablation and method therefor
FR2624747A1 (en) * 1987-12-18 1989-06-23 Delsanti Gerard REMOVABLE ENDO-ARTERIAL DEVICES FOR REPAIRING ARTERIAL WALL DECOLLEMENTS
SE8800019D0 (en) 1988-01-07 1988-01-07 Knut Olof Edhag FOR CARDIALLY DEFIBLATION USED INTRAVASCULES ELECTRO CABLE
US4921484A (en) 1988-07-25 1990-05-01 Cordis Corporation Mesh balloon catheter device
US5005587A (en) 1989-11-13 1991-04-09 Pacing Systems, Inc. Braid Electrode leads and catheters and methods for using the same
US5041093A (en) * 1990-01-31 1991-08-20 Boston Scientific Corp. Catheter with foraminous anchor
US5100423A (en) * 1990-08-21 1992-03-31 Medical Engineering & Development Institute, Inc. Ablation catheter
US5465717A (en) 1991-02-15 1995-11-14 Cardiac Pathways Corporation Apparatus and Method for ventricular mapping and ablation
AU660444B2 (en) 1991-02-15 1995-06-29 Ingemar H. Lundquist Torquable catheter and method
US5415166A (en) 1991-02-15 1995-05-16 Cardiac Pathways Corporation Endocardial mapping apparatus and cylindrical semiconductor device mounting structure for use therewith and method
US5156151A (en) * 1991-02-15 1992-10-20 Cardiac Pathways Corporation Endocardial mapping and ablation system and catheter probe
US6029671A (en) 1991-07-16 2000-02-29 Heartport, Inc. System and methods for performing endovascular procedures
US5190542A (en) * 1991-11-05 1993-03-02 Nakao Naomi L Surgical retrieval assembly and related method
US5509411A (en) 1993-01-29 1996-04-23 Cardima, Inc. Intravascular sensing device
US5263493A (en) 1992-02-24 1993-11-23 Boaz Avitall Deflectable loop electrode array mapping and ablation catheter for cardiac chambers
SE9200803D0 (en) * 1992-03-16 1992-03-16 Siemens Elema Ab defibrillation
US5255679A (en) 1992-06-02 1993-10-26 Cardiac Pathways Corporation Endocardial catheter for mapping and/or ablation with an expandable basket structure having means for providing selective reinforcement and pressure sensing mechanism for use therewith, and method
US5324284A (en) 1992-06-05 1994-06-28 Cardiac Pathways, Inc. Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method
WO1994000178A1 (en) 1992-06-26 1994-01-06 Schneider (Usa) Inc. Catheter with expandable wire mesh tip
US5311866A (en) * 1992-09-23 1994-05-17 Endocardial Therapeutics, Inc. Heart mapping catheter
EP0661948B1 (en) 1992-09-23 1997-11-19 Endocardial Solutions, Inc. Endocardial mapping system
US6647617B1 (en) 1992-09-23 2003-11-18 Graydon Ernest Beatty Method of construction an endocardial mapping catheter
US6240307B1 (en) * 1993-09-23 2001-05-29 Endocardial Solutions, Inc. Endocardial mapping system
US5313943A (en) 1992-09-25 1994-05-24 Ep Technologies, Inc. Catheters and methods for performing cardiac diagnosis and treatment
US5309910A (en) * 1992-09-25 1994-05-10 Ep Technologies, Inc. Cardiac mapping and ablation systems
US5549108A (en) 1992-09-25 1996-08-27 Ep Technologies, Inc. Cardiac mapping and ablation systems
GB2271932B (en) 1992-11-03 1996-05-08 George Thomas Watts Surgical instrument for tissue coagulation
US5383852A (en) 1992-12-04 1995-01-24 C. R. Bard, Inc. Catheter with independent proximal and distal control
US5462527A (en) 1993-06-29 1995-10-31 C.R. Bard, Inc. Actuator for use with steerable catheter
US5433198A (en) 1993-03-11 1995-07-18 Desai; Jawahar M. Apparatus and method for cardiac ablation
US5636634A (en) 1993-03-16 1997-06-10 Ep Technologies, Inc. Systems using guide sheaths for introducing, deploying, and stabilizing cardiac mapping and ablation probes
EP0673225A4 (en) 1993-03-16 1996-01-24 Ep Technologies Cardiac mapping and ablation systems.
US5476495A (en) 1993-03-16 1995-12-19 Ep Technologies, Inc. Cardiac mapping and ablation systems
US5403311A (en) * 1993-03-29 1995-04-04 Boston Scientific Corporation Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue
US5611777A (en) 1993-05-14 1997-03-18 C.R. Bard, Inc. Steerable electrode catheter
US5860974A (en) 1993-07-01 1999-01-19 Boston Scientific Corporation Heart ablation catheter with expandable electrode and method of coupling energy to an electrode on a catheter shaft
EP0706345B1 (en) 1993-07-01 2003-02-19 Boston Scientific Limited Imaging, electrical potential sensing, and ablation catheters
US5921982A (en) * 1993-07-30 1999-07-13 Lesh; Michael D. Systems and methods for ablating body tissue
US5409000A (en) 1993-09-14 1995-04-25 Cardiac Pathways Corporation Endocardial mapping and ablation system utilizing separately controlled steerable ablation catheter with ultrasonic imaging capabilities and method
US5400783A (en) 1993-10-12 1995-03-28 Cardiac Pathways Corporation Endocardial mapping apparatus with rotatable arm and method
WO1995010319A1 (en) 1993-10-15 1995-04-20 Ep Technologies, Inc. Electrodes for creating lesions in body tissue
US6146379A (en) 1993-10-15 2000-11-14 Ep Technologies, Inc. Systems and methods for creating curvilinear lesions in body tissue
US5575810A (en) 1993-10-15 1996-11-19 Ep Technologies, Inc. Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like
US6001093A (en) 1993-10-15 1999-12-14 Ep Technologies, Inc. Systems and methods for creating long, thin lesions in body tissue
US5454370A (en) * 1993-12-03 1995-10-03 Avitall; Boaz Mapping and ablation electrode configuration
US5487385A (en) * 1993-12-03 1996-01-30 Avitall; Boaz Atrial mapping and ablation catheter system
US5462521A (en) * 1993-12-21 1995-10-31 Angeion Corporation Fluid cooled and perfused tip for a catheter
US5968040A (en) 1994-03-04 1999-10-19 Ep Technologies, Inc. Systems and methods using asymmetric multiple electrode arrays
US5680860A (en) 1994-07-07 1997-10-28 Cardiac Pathways Corporation Mapping and/or ablation catheter with coilable distal extremity and method for using same
US5725552A (en) 1994-07-08 1998-03-10 Aga Medical Corporation Percutaneous catheter directed intravascular occlusion devices
DE4425195C1 (en) 1994-07-16 1995-11-16 Osypka Peter Heart catheter with multiple electrode device
US6572609B1 (en) 1999-07-14 2003-06-03 Cardiofocus, Inc. Phototherapeutic waveguide apparatus
US5836947A (en) 1994-10-07 1998-11-17 Ep Technologies, Inc. Flexible structures having movable splines for supporting electrode elements
US6142994A (en) 1994-10-07 2000-11-07 Ep Technologies, Inc. Surgical method and apparatus for positioning a diagnostic a therapeutic element within the body
US5885278A (en) 1994-10-07 1999-03-23 E.P. Technologies, Inc. Structures for deploying movable electrode elements
US5722401A (en) 1994-10-19 1998-03-03 Cardiac Pathways Corporation Endocardial mapping and/or ablation catheter probe
US5542434A (en) * 1994-10-28 1996-08-06 Intelliwire Inc. Guide wire with deflectable tip and method
CA2208795A1 (en) * 1994-12-27 1996-07-04 Advanced Cardiovascular Systems, Inc. Catheter with reinforced oblong transverse cross section
US5595183A (en) 1995-02-17 1997-01-21 Ep Technologies, Inc. Systems and methods for examining heart tissue employing multiple electrode structures and roving electrodes
US5681280A (en) * 1995-05-02 1997-10-28 Heart Rhythm Technologies, Inc. Catheter control system
US5702438A (en) 1995-06-08 1997-12-30 Avitall; Boaz Expandable recording and ablation catheter system
US6023638A (en) * 1995-07-28 2000-02-08 Scimed Life Systems, Inc. System and method for conducting electrophysiological testing using high-voltage energy pulses to stun tissue
US5925038A (en) 1996-01-19 1999-07-20 Ep Technologies, Inc. Expandable-collapsible electrode structures for capacitive coupling to tissue
US5879348A (en) 1996-04-12 1999-03-09 Ep Technologies, Inc. Electrode structures formed from flexible, porous, or woven materials
US5891136A (en) * 1996-01-19 1999-04-06 Ep Technologies, Inc. Expandable-collapsible mesh electrode structures
US5800482A (en) * 1996-03-06 1998-09-01 Cardiac Pathways Corporation Apparatus and method for linear lesion ablation
US5769880A (en) * 1996-04-12 1998-06-23 Novacept Moisture transport system for contact electrocoagulation
US6237605B1 (en) * 1996-10-22 2001-05-29 Epicor, Inc. Methods of epicardial ablation
US5722403A (en) 1996-10-28 1998-03-03 Ep Technologies, Inc. Systems and methods using a porous electrode for ablating and visualizing interior tissue regions
US5752518A (en) * 1996-10-28 1998-05-19 Ep Technologies, Inc. Systems and methods for visualizing interior regions of the body
US5893885A (en) 1996-11-01 1999-04-13 Cordis Webster, Inc. Multi-electrode ablation catheter
US6480746B1 (en) 1997-08-13 2002-11-12 Surx, Inc. Noninvasive devices, methods, and systems for shrinking of tissues
EP0842640A1 (en) 1996-11-13 1998-05-20 Sulzer Osypka GmbH Heart catheter with electrode positioned on a distensible element
US5916213A (en) 1997-02-04 1999-06-29 Medtronic, Inc. Systems and methods for tissue mapping and ablation
US6012457A (en) * 1997-07-08 2000-01-11 The Regents Of The University Of California Device and method for forming a circumferential conduction block in a pulmonary vein
US5904698A (en) * 1997-06-10 1999-05-18 Applied Medical Resources Corporation Surgical shaving device for use within body conduits
ATE433306T1 (en) * 1997-07-08 2009-06-15 Univ California DEVICE FOR CIRCUMFERENTIAL ABLATION
US6652515B1 (en) * 1997-07-08 2003-11-25 Atrionix, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
US6500174B1 (en) * 1997-07-08 2002-12-31 Atrionix, Inc. Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member
US5928260A (en) * 1997-07-10 1999-07-27 Scimed Life Systems, Inc. Removable occlusion system for aneurysm neck
EP1017442B1 (en) 1997-09-23 2005-01-12 United States Surgical Corporation Catheter with stand-off structure
US6468272B1 (en) 1997-10-10 2002-10-22 Scimed Life Systems, Inc. Surgical probe for supporting diagnostic and therapeutic elements in contact with tissue in or around body orifices
US6183463B1 (en) * 1997-12-01 2001-02-06 Cordis Webster, Inc. Bidirectional steerable cathether with bidirectional control handle
US6917834B2 (en) * 1997-12-03 2005-07-12 Boston Scientific Scimed, Inc. Devices and methods for creating lesions in endocardial and surrounding tissue to isolate focal arrhythmia substrates
US5931863A (en) 1997-12-22 1999-08-03 Procath Corporation Electrophysiology catheter
JP2002508989A (en) * 1998-01-14 2002-03-26 キューロン メディカル，インコーポレイテッド Electrosurgical instruments and methods for treating gastroesophageal reflux disease (GERD)
US5944738A (en) 1998-02-06 1999-08-31 Aga Medical Corporation Percutaneous catheter directed constricting occlusion device
US6142993A (en) 1998-02-27 2000-11-07 Ep Technologies, Inc. Collapsible spline structure using a balloon as an expanding actuator
US5951471A (en) * 1998-03-09 1999-09-14 Irvine Biomedical, Inc. Catheter-based coronary sinus mapping and ablation
US6522930B1 (en) * 1998-05-06 2003-02-18 Atrionix, Inc. Irrigated ablation device assembly
US6231572B1 (en) 1998-05-29 2001-05-15 Applied Medical Resources Corporation Electrosurgical catheter apparatus and method
SE9802104D0 (en) 1998-06-12 1998-06-12 Pacesetter Ab Medical electrode device
US6119030A (en) 1998-06-22 2000-09-12 Ep Technologies, Inc. Silicone tip for multiple electrode basket assemblies
US6673290B1 (en) 1998-11-12 2004-01-06 Scimed Life Systems, Inc. Electrode structure for heating and ablating tissue and method for making and assembling the same
US6178354B1 (en) 1998-12-02 2001-01-23 C. R. Bard, Inc. Internal mechanism for displacing a slidable electrode
US6702811B2 (en) 1999-04-05 2004-03-09 Medtronic, Inc. Ablation catheter assembly with radially decreasing helix and method of use
US20010007070A1 (en) * 1999-04-05 2001-07-05 Medtronic, Inc. Ablation catheter assembly and method for isolating a pulmonary vein
US6375668B1 (en) * 1999-06-02 2002-04-23 Hanson S. Gifford Devices and methods for treating vascular malformations
US20020169473A1 (en) 1999-06-02 2002-11-14 Concentric Medical, Inc. Devices and methods for treating vascular malformations
US6616655B1 (en) * 1999-06-03 2003-09-09 C. R. Bard, Inc. Method and apparatus for performing cardiac ablations
US6315778B1 (en) * 1999-09-10 2001-11-13 C. R. Bard, Inc. Apparatus for creating a continuous annular lesion
DE60037747T2 (en) * 1999-11-10 2008-12-11 Cytyc Surgical Products, Palo Alto SYSTEM FOR FIXING PERFORATIONS IN A BODY CAVITY
US6529756B1 (en) * 1999-11-22 2003-03-04 Scimed Life Systems, Inc. Apparatus for mapping and coagulating soft tissue in or around body orifices
US6613046B1 (en) * 1999-11-22 2003-09-02 Scimed Life Systems, Inc. Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
US6652517B1 (en) 2000-04-25 2003-11-25 Uab Research Foundation Ablation catheter, system, and method of use thereof
ATE427711T1 (en) * 2000-05-03 2009-04-15 Bard Inc C R DEVICE FOR IMAGING AND ABLATION IN ELECTROPHYSIOLOGICAL PROCEDURES
WO2002087437A1 (en) 2001-04-27 2002-11-07 C.R. Bard, Inc. Catheter for three dimensional mapping of electrical activity in blood vessels and ablation procedure
WO2002087456A1 (en) 2001-05-01 2002-11-07 C.R. Bard, Inc. Method and apparatus for altering conduction properties in the heart and in adjacent vessels
US7727229B2 (en) 2001-05-01 2010-06-01 C.R. Bard, Inc. Method and apparatus for altering conduction properties in the heart and in adjacent vessels
US6620159B2 (en) 2001-06-06 2003-09-16 Scimed Life Systems, Inc. Conductive expandable electrode body and method of manufacturing the same
US6741878B2 (en) 2001-12-14 2004-05-25 Biosense Webster, Inc. Basket catheter with improved expansion mechanism
US7089045B2 (en) 2002-08-30 2006-08-08 Biosense Webster, Inc. Catheter and method for mapping Purkinje fibers
DE602004011608T2 (en) 2003-03-28 2009-01-29 C.R. Bard, Inc. Catheter with braided mesh
WO2005112813A1 (en) 2004-05-17 2005-12-01 C.R. Bard, Inc. Method and apparatus for mapping and7or ablation of cardiac tissue

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9138250B2 (en) 2006-04-24 2015-09-22 Ethicon Endo-Surgery, Inc. Medical instrument handle and medical instrument having a handle
US8974445B2 (en) 2009-01-09 2015-03-10 Recor Medical, Inc. Methods and apparatus for treatment of cardiac valve insufficiency
US11878095B2 (en) 2018-12-11 2024-01-23 Biosense Webster (Israel) Ltd. Balloon catheter with high articulation
US11950930B2 (en) 2019-12-12 2024-04-09 Biosense Webster (Israel) Ltd. Multi-dimensional acquisition of bipolar signals from a catheter
US11918341B2 (en) 2019-12-20 2024-03-05 Biosense Webster (Israel) Ltd. Selective graphical presentation of electrophysiological parameters
US11950841B2 (en) 2020-09-22 2024-04-09 Biosense Webster (Israel) Ltd. Basket catheter having insulated ablation electrodes and diagnostic electrodes
US11950840B2 (en) 2020-09-22 2024-04-09 Biosense Webster (Israel) Ltd. Basket catheter having insulated ablation electrodes
US11918383B2 (en) 2020-12-21 2024-03-05 Biosense Webster (Israel) Ltd. Visualizing performance of catheter electrodes

Also Published As

Publication number Publication date
EP1284670B1 (en) 2009-06-03
DE60138880D1 (en) 2009-07-16
ATE432664T1 (en) 2009-06-15
EP1284670A2 (en) 2003-02-26
WO2001082814A3 (en) 2002-04-04
US8157796B2 (en) 2012-04-17
US6837886B2 (en) 2005-01-04
US20050065420A1 (en) 2005-03-24
US20020107511A1 (en) 2002-08-08
US20080058800A1 (en) 2008-03-06
US20120165815A1 (en) 2012-06-28
ATE427711T1 (en) 2009-04-15
DE60138319D1 (en) 2009-05-20
EP2095784A1 (en) 2009-09-02
WO2001082814A2 (en) 2001-11-08
US9028486B2 (en) 2015-05-12
JP4926359B2 (en) 2012-05-09
US7306594B2 (en) 2007-12-11
JP2003531667A (en) 2003-10-28
EP2095784B1 (en) 2016-01-06
EP1642544A1 (en) 2006-04-05
EP1642544B1 (en) 2009-04-08

Similar Documents

Publication Publication Date Title
WO2001082814B1 (en) Apparatus and methods for mapping and ablation in electrophysiology procedures
US7255695B2 (en) Systems and methods for three-dimensional mapping of electrical activity
US6360128B2 (en) Cardiac mapping and ablation systems
US7846157B2 (en) Method and apparatus for control of ablation energy and electrogram acquisition through multiple common electrodes in an electrophysiology catheter
US5476495A (en) Cardiac mapping and ablation systems
US5636634A (en) Systems using guide sheaths for introducing, deploying, and stabilizing cardiac mapping and ablation probes
US6972016B2 (en) Helically shaped electrophysiology catheter
US5680860A (en) Mapping and/or ablation catheter with coilable distal extremity and method for using same
US8951247B2 (en) Methods and apparatus for forming cardiac lesions and assessing lesion quality
US6029091A (en) Catheter system having lattice electrodes
US6475214B1 (en) Catheter with enhanced ablation electrode
US20040187875A1 (en) Method and apparatus for altering conduction properties along pathways in the heart and in vessels in conductive communication with the heart.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

WWE Wipo information: entry into national phase

Ref document number: 2001934942

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001934942

Country of ref document: EP