WO2001080839A3 - Utilisation de naphthindazol-4,9-chinones comme antiparasitaires - Google Patents

Utilisation de naphthindazol-4,9-chinones comme antiparasitaires Download PDF

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Publication number
WO2001080839A3
WO2001080839A3 PCT/DE2001/000975 DE0100975W WO0180839A3 WO 2001080839 A3 WO2001080839 A3 WO 2001080839A3 DE 0100975 W DE0100975 W DE 0100975W WO 0180839 A3 WO0180839 A3 WO 0180839A3
Authority
WO
WIPO (PCT)
Prior art keywords
spp
naphthindazole
quinones
compounds
general formula
Prior art date
Application number
PCT/DE2001/000975
Other languages
German (de)
English (en)
Other versions
WO2001080839A2 (fr
Inventor
Oliver Kayser
Hartmut Laatsch
Albrecht Ferdinand Kiderlen
Original Assignee
Bundesrep Deutschland
Oliver Kayser
Hartmut Laatsch
Albrecht Ferdinand Kiderlen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bundesrep Deutschland, Oliver Kayser, Hartmut Laatsch, Albrecht Ferdinand Kiderlen filed Critical Bundesrep Deutschland
Priority to AU2001250279A priority Critical patent/AU2001250279A1/en
Publication of WO2001080839A2 publication Critical patent/WO2001080839A2/fr
Publication of WO2001080839A3 publication Critical patent/WO2001080839A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des compositions pharmaceutiques caractérisées en ce qu'elle contiennent au moins un des composés de la formule générale (I) et leurs sels pharmaceutiquement compatibles ainsi que l'utilisation de composés de la formule générale (I) ou de leurs sels pharmaceutiquement compatibles aux fins d'administration préventive ou de traitement thérapeutique d'une infection parasitaire induite par Trypanosoma spp., Leishmania spp., Plasmodium spp., Cryptosporidium parvum, Eimeria spp., Toxoplasma gondii ou Pneumocystis spp.
PCT/DE2001/000975 2000-04-20 2001-03-09 Utilisation de naphthindazol-4,9-chinones comme antiparasitaires WO2001080839A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001250279A AU2001250279A1 (en) 2000-04-20 2001-03-09 Use of naphthindazole-4,9-quinones as antiparasitic agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10020812A DE10020812C2 (de) 2000-04-20 2000-04-20 Verwendung von Naphthindazol-4,9-chinonen als Antiparasitika
DE10020812.6 2000-04-20

Publications (2)

Publication Number Publication Date
WO2001080839A2 WO2001080839A2 (fr) 2001-11-01
WO2001080839A3 true WO2001080839A3 (fr) 2002-05-23

Family

ID=7640185

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2001/000975 WO2001080839A2 (fr) 2000-04-20 2001-03-09 Utilisation de naphthindazol-4,9-chinones comme antiparasitaires

Country Status (3)

Country Link
AU (1) AU2001250279A1 (fr)
DE (1) DE10020812C2 (fr)
WO (1) WO2001080839A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10203195A1 (de) * 2002-01-25 2003-08-07 Zentaris Ag Verwendung von Alkylphosphocholinen in der Präventivbehandlung von Protozoenerkrankungen
US7887817B2 (en) 2002-01-25 2011-02-15 Aeterna Zentaris Gmbh Process for preventing protozoal diseases
KR102511507B1 (ko) * 2020-09-16 2023-03-17 경희대학교 산학협력단 신규한 벤조인다졸트리온 유도체 및 이의 용도

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2107053A1 (de) * 1970-02-17 1971-08-26 Shell Internationale Research Maat schappij N V , Den Haag (Niederlande) Substituierte 1,4 Chinondenvate
DE3831332A1 (de) * 1988-09-15 1990-03-29 Basf Ag Naphthindazol-4,9-chinone und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2107053A1 (de) * 1970-02-17 1971-08-26 Shell Internationale Research Maat schappij N V , Den Haag (Niederlande) Substituierte 1,4 Chinondenvate
DE3831332A1 (de) * 1988-09-15 1990-03-29 Basf Ag Naphthindazol-4,9-chinone und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A. ZEECK ET AL.: "Isolierung und Konstitution der Isochromanchinon-Antibiotika beta- und gamma-Naphthocyclinon", LIEBIGS ANN. CHEM., no. 7, 1974, pages 1100 - 1025, XP001038515 *
B. KRONE, A. ZEECK: "13C-NMR and CD Spectroscopy with Isochromanquinones - Potent Methods To Determine the Stereochemistry and the Tautomeric Equilibrium in This Group of Antibiotics", LIEBIGS ANN. CHEM., no. 9, 1987, pages 751 - 758, XP001026139 *
H. LAATSCH: "Partialsynthese von Actinorhodin", LIEBIGS ANN. CHEM., no. 4, 1987, pages 297 - 304, XP001026119 *
S. DANOUN ET AL.: "Synthesis and protozoocidal activity of new 1,4-naphthoquinones", HETEROCYCL. COMMUN., vol. 5, no. 4, 1999, pages 343 - 348, XP001037195 *
V. K. TANDON ET AL.: "Synthesis and Pharmacoogical Studies of Some (1,4)-Naphthoquinon[3,2-c]-1H-pyrazoles, 2-Substituted Amino-1,4-nahthoquinones, and Related Compounds", ARCH. PHARM. (EINHEIM, GER.), vol. 323, no. 7, 1990, pages 383 - 385, XP001037273 *

Also Published As

Publication number Publication date
AU2001250279A1 (en) 2001-11-07
WO2001080839A2 (fr) 2001-11-01
DE10020812A1 (de) 2001-10-31
DE10020812C2 (de) 2003-06-26

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