WO2001079228A3 - Haplotypes of the f12 gene - Google Patents

Haplotypes of the f12 gene Download PDF

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Publication number
WO2001079228A3
WO2001079228A3 PCT/US2001/012257 US0112257W WO0179228A3 WO 2001079228 A3 WO2001079228 A3 WO 2001079228A3 US 0112257 W US0112257 W US 0112257W WO 0179228 A3 WO0179228 A3 WO 0179228A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene
haplotypes
disclosed
polymorphisms
haplotyping
Prior art date
Application number
PCT/US2001/012257
Other languages
French (fr)
Other versions
WO2001079228A2 (en
Inventor
Steven C Bentivegna
Anne Chew
Julie Y Choi
Krishnan Nandabalan
Original Assignee
Genaissance Pharmaceuticals
Steven C Bentivegna
Anne Chew
Julie Y Choi
Krishnan Nandabalan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Steven C Bentivegna, Anne Chew, Julie Y Choi, Krishnan Nandabalan filed Critical Genaissance Pharmaceuticals
Priority to AU5705101A priority Critical patent/AU5705101A/en
Publication of WO2001079228A2 publication Critical patent/WO2001079228A2/en
Publication of WO2001079228A3 publication Critical patent/WO2001079228A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Abstract

Novel single nucleotide polymorphisms in the human coagulation factor XII (F12) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the F12 gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the F12 gene in an individual are also disclosed. Polynucleotides containing one or more of the F12 polymorphisms disclosed herein are also described.
PCT/US2001/012257 2000-04-14 2001-04-13 Haplotypes of the f12 gene WO2001079228A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU5705101A AU5705101A (en) 2000-04-14 2001-04-13 Haplotypes of the f12 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19783700P 2000-04-14 2000-04-14
US60/197,837 2000-04-14

Publications (2)

Publication Number Publication Date
WO2001079228A2 WO2001079228A2 (en) 2001-10-25
WO2001079228A3 true WO2001079228A3 (en) 2002-07-04

Family

ID=22730935

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012257 WO2001079228A2 (en) 2000-04-14 2001-04-13 Haplotypes of the f12 gene

Country Status (2)

Country Link
AU (1) AU5705101A (en)
WO (1) WO2001079228A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1598428A1 (en) * 2004-05-18 2005-11-23 Georg Dewald Methods and kits to detect Hereditary angioedema type III
EP1954822A1 (en) * 2005-11-23 2008-08-13 Georg Dewald Detection and treatment of drug associated angioedema
CN107841554A (en) * 2017-11-24 2018-03-27 南京艾迪康医学检验所有限公司 Detect the primer, kit and method of Hageman factor (F12) gene mutation
IL286905B1 (en) * 2019-04-04 2024-02-01 Regeneron Pharma Non-human animals comprising a humanized coagulation factor 12 locus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCHLOESSER ET AL.: "Mutations in the human factor XII gene", BLOOD, vol. 90, no. 10, 15 November 1997 (1997-11-15), pages 3967 - 3977, XP002947400 *

Also Published As

Publication number Publication date
AU5705101A (en) 2001-10-30
WO2001079228A2 (en) 2001-10-25

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