WO2001079222A3 - Haplotypes du gene mc4r - Google Patents

Haplotypes du gene mc4r Download PDF

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Publication number
WO2001079222A3
WO2001079222A3 PCT/US2001/011943 US0111943W WO0179222A3 WO 2001079222 A3 WO2001079222 A3 WO 2001079222A3 US 0111943 W US0111943 W US 0111943W WO 0179222 A3 WO0179222 A3 WO 0179222A3
Authority
WO
WIPO (PCT)
Prior art keywords
mc4r
gene
haplotypes
mc4r gene
disclosed
Prior art date
Application number
PCT/US2001/011943
Other languages
English (en)
Other versions
WO2001079222A2 (fr
Inventor
Steven C Bentivegna
Julie Y Choi
Amir Kazemi
Helen H Lee
Krishnan Nandabalan
Katie E Parks
Elizabeth Ann Sausker
Original Assignee
Genaissance Pharmaceuticals
Steven C Bentivegna
Julie Y Choi
Amir Kazemi
Helen H Lee
Krishnan Nandabalan
Katie E Parks
Elizabeth Ann Sausker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Steven C Bentivegna, Julie Y Choi, Amir Kazemi, Helen H Lee, Krishnan Nandabalan, Katie E Parks, Elizabeth Ann Sausker filed Critical Genaissance Pharmaceuticals
Priority to AU2001255329A priority Critical patent/AU2001255329A1/en
Priority to PCT/US2001/011943 priority patent/WO2001079222A2/fr
Publication of WO2001079222A2 publication Critical patent/WO2001079222A2/fr
Publication of WO2001079222A3 publication Critical patent/WO2001079222A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des nouveaux polymorphismes mononucléotidiques dans le gène humain du récepteur 4 de la mélanocortine (MC4R). L'invention concerne également divers génotypes, haplotypes et paires d'haplotypes pour le gène MC4R existant dans la population. L'invention concerne également des compositions et des procédés permettant d'haplotyper et/ou de génotyper le gène MC4R dans un individu. L'invention concerne également des polynucléotides renfermant un ou plusieurs des polymorphismes du MC4R susmentionnés.
PCT/US2001/011943 2000-04-12 2001-04-12 Haplotypes du gene mc4r WO2001079222A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001255329A AU2001255329A1 (en) 2000-04-12 2001-04-12 Haplotypes of the mc4r gene
PCT/US2001/011943 WO2001079222A2 (fr) 2000-04-12 2001-04-12 Haplotypes du gene mc4r

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60/196,677 2000-04-12
PCT/US2001/011943 WO2001079222A2 (fr) 2000-04-12 2001-04-12 Haplotypes du gene mc4r

Publications (2)

Publication Number Publication Date
WO2001079222A2 WO2001079222A2 (fr) 2001-10-25
WO2001079222A3 true WO2001079222A3 (fr) 2009-06-04

Family

ID=40679250

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011943 WO2001079222A2 (fr) 2000-04-12 2001-04-12 Haplotypes du gene mc4r

Country Status (1)

Country Link
WO (1) WO2001079222A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622860A (en) * 1994-02-17 1997-04-22 The Regents Of The University Of Michigan Genes encoding melanocortin receptors
US5908609A (en) * 1996-06-10 1999-06-01 Millennium Pharmaceuticals, Inc. Screening methods for compounds useful in the regulation of body weight
WO2000006777A2 (fr) * 1998-07-27 2000-02-10 Iowa State University Research Foundation, Inc. Gene recepteur de melanocortine 4 et son utilisation comme marqueur genetique de la teneur en matieres grasses, de la prise de poids et/ou de la consommation d'aliments chez des animaux

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622860A (en) * 1994-02-17 1997-04-22 The Regents Of The University Of Michigan Genes encoding melanocortin receptors
US5908609A (en) * 1996-06-10 1999-06-01 Millennium Pharmaceuticals, Inc. Screening methods for compounds useful in the regulation of body weight
WO2000006777A2 (fr) * 1998-07-27 2000-02-10 Iowa State University Research Foundation, Inc. Gene recepteur de melanocortine 4 et son utilisation comme marqueur genetique de la teneur en matieres grasses, de la prise de poids et/ou de la consommation d'aliments chez des animaux

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GANTZ ET AL.: "Molecular cloning, Expression and gene localization of a fourth melanocortin receptor", J. BIOL. CHEM., vol. 268, no. 20, 15 July 1993 (1993-07-15), pages 15174 - 15179, XP002944423 *
KIM ET AL.: "A missense variant of the porcine melanocortin-4 receptor (MC4R) gene is associated with fatness, growth and feed intake traits", MAMMALIAN GENOME, vol. 11, February 2000 (2000-02-01), pages 131 - 135, XP002944421 *
OHSHIRO ET AL.: "Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic japanese", ANNALS OF HUMAN GENETICS, vol. 63, 1999, pages 1 PAGE, XP002944422 *

Also Published As

Publication number Publication date
WO2001079222A2 (fr) 2001-10-25

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