WO2001074833A3 - Haplotypes du gene chrnb2 - Google Patents

Haplotypes du gene chrnb2 Download PDF

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Publication number
WO2001074833A3
WO2001074833A3 PCT/US2001/010666 US0110666W WO0174833A3 WO 2001074833 A3 WO2001074833 A3 WO 2001074833A3 US 0110666 W US0110666 W US 0110666W WO 0174833 A3 WO0174833 A3 WO 0174833A3
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WO
WIPO (PCT)
Prior art keywords
chrnb2
gene
haplotypes
disclosed
polymorphisms
Prior art date
Application number
PCT/US2001/010666
Other languages
English (en)
Other versions
WO2001074833A2 (fr
Inventor
Julie Y Choi
Stefanie E Kliem
Beena Koshy
Helen H Lee
Angela Sanchis
Original Assignee
Genaissance Pharmaceuticals
Julie Y Choi
Stefanie E Kliem
Beena Koshy
Helen H Lee
Angela Sanchis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Julie Y Choi, Stefanie E Kliem, Beena Koshy, Helen H Lee, Angela Sanchis filed Critical Genaissance Pharmaceuticals
Priority to AU2001251243A priority Critical patent/AU2001251243A1/en
Publication of WO2001074833A2 publication Critical patent/WO2001074833A2/fr
Publication of WO2001074833A3 publication Critical patent/WO2001074833A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Artificial Intelligence (AREA)
  • Ecology (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne de nouveaux polymorphismes nucléotidiques simples dans le gène humain récepteur cholinergique nicotinique polypeptide bêta 2 (neuronal) (CHRNB2). En outre, l'invention concerne également différents génotypes, haplotypes et paires d'haplotypes du gène CHRNB2 existant dans la population. Cette invention porte aussi sur des compositions et des procédés pour haplotyper et/ou génotyper le gène CHRNB2 chez un individu, ainsi que sur des polynucléotides contenant un ou plusieurs polymorphismes CHRNB2.
PCT/US2001/010666 2000-04-03 2001-04-03 Haplotypes du gene chrnb2 WO2001074833A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001251243A AU2001251243A1 (en) 2000-04-03 2001-04-03 Haplotypes of the chrnb2 gene

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19415500P 2000-04-03 2000-04-03
US60/194,155 2000-04-03
US21795200P 2000-07-13 2000-07-13
US60/217,952 2000-07-13

Publications (2)

Publication Number Publication Date
WO2001074833A2 WO2001074833A2 (fr) 2001-10-11
WO2001074833A3 true WO2001074833A3 (fr) 2002-03-07

Family

ID=26889742

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/010666 WO2001074833A2 (fr) 2000-04-03 2001-04-03 Haplotypes du gene chrnb2

Country Status (2)

Country Link
AU (1) AU2001251243A1 (fr)
WO (1) WO2001074833A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL160651A0 (en) 2001-08-31 2004-07-25 Agensys Inc Nucleic acid and correspondidng protein entitled 205pib5 and pharmaceutical compositions containing the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
REMPEL ET AL.: "The structures of the human neuronal nicotinic acetylcholine receptor beta2- and alpha3-subunit genes (CHRNB2 and CHRNA3)", HUMAN GENETICS, vol. 103, December 1998 (1998-12-01), pages 645 - 653, XP002947187 *
SILVERMAN ET AL.: "Haplotypes of four novel single nucleotide polymorphisms in the nicotinic acetylcholine receptor beta2-subunit (CHRNB2) gene show no association with smoking initiation or nicotine dependence", AMERICAN JOURNAL OF MEDICAL GENETICS, vol. 96, October 2000 (2000-10-01), pages 646 - 653, XP002947186 *

Also Published As

Publication number Publication date
AU2001251243A1 (en) 2001-10-15
WO2001074833A2 (fr) 2001-10-11

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