WO2001062918A3 - Secretory polypeptides and corresponding polynucleotides - Google Patents

Secretory polypeptides and corresponding polynucleotides Download PDF

Info

Publication number
WO2001062918A3
WO2001062918A3 PCT/US2001/003465 US0103465W WO0162918A3 WO 2001062918 A3 WO2001062918 A3 WO 2001062918A3 US 0103465 W US0103465 W US 0103465W WO 0162918 A3 WO0162918 A3 WO 0162918A3
Authority
WO
WIPO (PCT)
Prior art keywords
sptm
provides
polypeptides
diagnostic assays
corresponding polynucleotides
Prior art date
Application number
PCT/US2001/003465
Other languages
French (fr)
Other versions
WO2001062918A2 (en
Inventor
Scott Panzer
Peter A Spiro
Steven C Banville
Purvi Shah
Michael S Chalup
Simon C Chang
Alice Chen
Steven A D'sa
Stefan Amshey
Christopher R Dahl
Tam C Dam
Susan E Daniels
Gerard E Dufour
Vincent Flores
Willy T Fong
Lila B Greenawalt
Jennifer L Hillman
Anissa L Jones
Tommy F Liu
Ann M Roseberry
Bruce H Rosen
Frank D Russo
Theresa K Stockdreher
Abel Daffo
Rachel J Wright
Pierre E Yap
Jimmy Y Yu
Diana L Bradley
Shawn R Bratcher
Wensheng Chen
Howard J Cohen
David M Hodgson
Stephen E Lincoln
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to CA002418496A priority Critical patent/CA2418496A1/en
Priority to EP01908799A priority patent/EP1263949A2/en
Priority to AU2001236631A priority patent/AU2001236631A1/en
Publication of WO2001062918A2 publication Critical patent/WO2001062918A2/en
Publication of WO2001062918A3 publication Critical patent/WO2001062918A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides purified secretory polynucleotides (sptm). Also encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sptm and methods of use.
PCT/US2001/003465 2000-02-24 2001-02-01 Secretory polypeptides and corresponding polynucleotides WO2001062918A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002418496A CA2418496A1 (en) 2000-02-24 2001-02-01 Secretory polypeptides and corresponding polynucleotides
EP01908799A EP1263949A2 (en) 2000-02-24 2001-02-01 Secretory polypeptides and corresponding polynucleotides
AU2001236631A AU2001236631A1 (en) 2000-02-24 2001-02-01 Secretory molecules

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US18521600P 2000-02-24 2000-02-24
US18521500P 2000-02-24 2000-02-24
US60/185,215 2000-02-24
US60/185,216 2000-02-24
US20523200P 2000-05-16 2000-05-16
US60/205,232 2000-05-16
US20528600P 2000-05-17 2000-05-17
US20528700P 2000-05-17 2000-05-17
US20532300P 2000-05-17 2000-05-17
US20532400P 2000-05-17 2000-05-17
US60/205,323 2000-05-17
US60/205,286 2000-05-17
US60/205,287 2000-05-17
US60/205,324 2000-05-17

Publications (2)

Publication Number Publication Date
WO2001062918A2 WO2001062918A2 (en) 2001-08-30
WO2001062918A3 true WO2001062918A3 (en) 2002-04-18

Family

ID=27569200

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/003465 WO2001062918A2 (en) 2000-02-24 2001-02-01 Secretory polypeptides and corresponding polynucleotides

Country Status (4)

Country Link
EP (1) EP1263949A2 (en)
AU (1) AU2001236631A1 (en)
CA (1) CA2418496A1 (en)
WO (1) WO2001062918A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7238790B2 (en) * 1999-01-12 2007-07-03 Genentech, Inc. PRO1313 polypeptides
US20020132298A1 (en) * 2000-11-14 2002-09-19 Millennium Pharmaceuticals, Inc. 67118, 67067, and 62092, human proteins and methods of use thereof
CA2419943A1 (en) * 2000-09-05 2002-03-14 Incyte Genomics, Inc. Secretory molecules
GB2397577A (en) * 2001-11-01 2004-07-28 Amersham Plc Human angiomotin-like protein 1
AU2004220156B2 (en) * 2003-03-14 2007-04-19 Taisho Pharmaceutical Co., Ltd. Monoclonal antibody and hybridoma producing the same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045712A2 (en) * 1997-04-08 1998-10-15 Human Genome Sciences, Inc. 20 human secreted proteins
WO1998048274A1 (en) * 1997-04-22 1998-10-29 Smithkline Beecham Corporation Homogeneous fluorescence assay for measuring the effect of compounds on gene expression
WO1999025825A2 (en) * 1997-11-13 1999-05-27 Genset EXTENDED cDNAs FOR SECRETED PROTEINS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045712A2 (en) * 1997-04-08 1998-10-15 Human Genome Sciences, Inc. 20 human secreted proteins
WO1998048274A1 (en) * 1997-04-22 1998-10-29 Smithkline Beecham Corporation Homogeneous fluorescence assay for measuring the effect of compounds on gene expression
WO1999025825A2 (en) * 1997-11-13 1999-05-27 Genset EXTENDED cDNAs FOR SECRETED PROTEINS

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 22 February 2000 (2000-02-22), ISOGAI T. ET AL.: "Homo sapiens cDNA FLJ10381 fis, clone NT2RM2002055.", XP002172579, retrieved from EBI Database accession no. AK001243 *

Also Published As

Publication number Publication date
WO2001062918A2 (en) 2001-08-30
EP1263949A2 (en) 2002-12-11
AU2001236631A1 (en) 2001-09-03
CA2418496A1 (en) 2001-08-30

Similar Documents

Publication Publication Date Title
WO2002097031A3 (en) Molecules for diagnostics and therapeutics
WO2004023973A3 (en) Molecules for diagnostics and therapeutics
WO2002083876A3 (en) Secretory molecules
WO2001004264A3 (en) Atherosclerosis-associated genes
WO2000073509A3 (en) Molecules for diagnostics and therapeutics
EP0897004A3 (en) Histidyl tRNA synthetase from Streptococcus pneumoniae (hisS)
EP0832977A3 (en) Novel sugar kinase
EP0893496A3 (en) Histidyl tRNA synthetase from Chlamydia trachomatis
WO2002062999A3 (en) Proteins and nucleic acids encoding same
WO2003020894A3 (en) Insulin related transcription factor and uses thereof
WO2002046228A3 (en) Receptor for b. anthracis toxin
WO2002059315A3 (en) Human nucleic acids and polypeptides and methods of use thereof
WO2002020756A3 (en) Secretory molecules
WO2002040715A8 (en) Molecules for disease detection and treatment
WO2003062376A3 (en) Molecules for diagnostics and therapeutics
WO2001062918A3 (en) Secretory polypeptides and corresponding polynucleotides
WO2003062385A3 (en) Secretory molecules
WO1999051547A3 (en) Solid phase synthesis of organic compounds via phosphitylating reagents
WO2001062927A3 (en) Polypeptides and corresponding polynucleotides for diagnostics and therapeutics
WO2001062922A3 (en) Polypeptides and corresponding molecules for disease detection and treatment
WO2002020754A3 (en) Molecules for diagnostics and therapeutics
WO2002057304A3 (en) Secretory molecules
WO2002055738A3 (en) Molecules for disease detection and treatment
WO2001023558A3 (en) Human secretory molecules
WO2002079473A3 (en) Molecules for diagnostics and therapeutics

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 10204887

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2001908799

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWP Wipo information: published in national office

Ref document number: 2001908799

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2418496

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Ref document number: 2001908799

Country of ref document: EP