WO2001056593A3 - Utilisation du facteur de croissance endothelial vasculaire, du facteur de croissance placentaire ou des deux pour prevenir ou traiter les maladies ischemiques ou les attaques - Google Patents

Utilisation du facteur de croissance endothelial vasculaire, du facteur de croissance placentaire ou des deux pour prevenir ou traiter les maladies ischemiques ou les attaques Download PDF

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Publication number
WO2001056593A3
WO2001056593A3 PCT/EP2001/001208 EP0101208W WO0156593A3 WO 2001056593 A3 WO2001056593 A3 WO 2001056593A3 EP 0101208 W EP0101208 W EP 0101208W WO 0156593 A3 WO0156593 A3 WO 0156593A3
Authority
WO
WIPO (PCT)
Prior art keywords
growth factor
stroke
vascular endothelial
preventing
ischemic diseases
Prior art date
Application number
PCT/EP2001/001208
Other languages
English (en)
Other versions
WO2001056593A2 (fr
Inventor
Peter Carmeliet
Desire Collen
Original Assignee
Peter Carmeliet
Desire Collen
D Collen Research
Flanders Univ Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0002527A external-priority patent/GB0002527D0/en
Application filed by Peter Carmeliet, Desire Collen, D Collen Research, Flanders Univ Inst filed Critical Peter Carmeliet
Priority to EP01902406A priority Critical patent/EP1253935B1/fr
Priority to JP2001556492A priority patent/JP4969753B2/ja
Priority to DE60119285T priority patent/DE60119285T2/de
Priority to AU2001230243A priority patent/AU2001230243A1/en
Priority to US10/182,359 priority patent/US6930089B2/en
Publication of WO2001056593A2 publication Critical patent/WO2001056593A2/fr
Publication of WO2001056593A3 publication Critical patent/WO2001056593A3/fr
Priority to US11/471,823 priority patent/US7727971B2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1891—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pressure Vessels And Lids Thereof (AREA)
  • Dowels (AREA)
  • Clamps And Clips (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

L'invention concerne le facteur de croissance vasculaire endothéliale, le facteur de croissance placentaire, ou des combinaisons des deux, notamment des hétéodimères, utilisés pour traiter ou prévenir les attaques ou les maladies ischémiques chez les mammifères.
PCT/EP2001/001208 2000-02-04 2001-02-05 Utilisation du facteur de croissance endothelial vasculaire, du facteur de croissance placentaire ou des deux pour prevenir ou traiter les maladies ischemiques ou les attaques WO2001056593A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP01902406A EP1253935B1 (fr) 2000-02-04 2001-02-05 Utilisation du facteur de croissance placentaire pour prevenir ou traiter les maladies ischemiques ou les attaques
JP2001556492A JP4969753B2 (ja) 2000-02-04 2001-02-05 虚血性疾患の処置の間に梗塞の大きさを低減するための医薬組成物
DE60119285T DE60119285T2 (de) 2000-02-04 2001-02-05 Verwendung von plgf zur vorbeugung oder behandlung von ischaemie oder schlaganfall
AU2001230243A AU2001230243A1 (en) 2000-02-04 2001-02-05 Use of vascular endothelial growth factor, placenta growth factor or both for preventing or treating ischemic diseases or stroke
US10/182,359 US6930089B2 (en) 2000-02-04 2001-02-05 Use of vascular endothelial growth factor, placenta growth factor or both for preventing or treating ischemic disease or stroke
US11/471,823 US7727971B2 (en) 2000-02-04 2006-06-21 Use of placental growth factor for treating ischemic muscle disease

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0002527.0 2000-02-04
GB0002527A GB0002527D0 (en) 2000-02-04 2000-02-04 Use of vascular endothelial growth factor (VEGF) placental growth factor (PLGF)or both for the treatment of ischemic and acute myocardial infaction
US23659400P 2000-09-29 2000-09-29
US60/236,594 2000-09-29

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10182359 A-371-Of-International 2001-02-05
US10/454,242 Continuation-In-Part US7105168B1 (en) 2000-02-04 2003-06-04 Method of improving ischemic muscle function by administering placental growth factor

Publications (2)

Publication Number Publication Date
WO2001056593A2 WO2001056593A2 (fr) 2001-08-09
WO2001056593A3 true WO2001056593A3 (fr) 2002-04-25

Family

ID=26243563

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2001/001659 WO2001057181A2 (fr) 2000-02-04 2001-02-02 UTILISATION DU FACTEUR DE CROISSANCE ENDOTHELIAL VASCULAIRE, DU FACTEUR DE CROISSANCE DU PLACENTA OU DES DEUX FACTEURS DANS LA PREVENTION OU LE TRAITEMENT DE MALADIES ISCHEMIQUES OU D'ACCIDENTS CEREBROVASCULAIRES
PCT/EP2001/001208 WO2001056593A2 (fr) 2000-02-04 2001-02-05 Utilisation du facteur de croissance endothelial vasculaire, du facteur de croissance placentaire ou des deux pour prevenir ou traiter les maladies ischemiques ou les attaques

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/001659 WO2001057181A2 (fr) 2000-02-04 2001-02-02 UTILISATION DU FACTEUR DE CROISSANCE ENDOTHELIAL VASCULAIRE, DU FACTEUR DE CROISSANCE DU PLACENTA OU DES DEUX FACTEURS DANS LA PREVENTION OU LE TRAITEMENT DE MALADIES ISCHEMIQUES OU D'ACCIDENTS CEREBROVASCULAIRES

Country Status (9)

Country Link
EP (1) EP1253935B1 (fr)
JP (1) JP4969753B2 (fr)
AT (1) ATE324905T1 (fr)
AU (2) AU4643501A (fr)
DE (1) DE60119285T2 (fr)
DK (1) DK1253935T3 (fr)
ES (1) ES2263582T3 (fr)
PT (1) PT1253935E (fr)
WO (2) WO2001057181A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2405291A1 (fr) * 2000-04-06 2001-10-18 Wayne P. Franco Methodes d'utilisation de facteurs de croissance pour traiter une cardiopathie
ES2299590T3 (es) * 2001-08-10 2008-06-01 Imclone Systems, Inc. Uso medico de celulas madre que expresan vegfr-1.ng vegfr-1.
ITRM20020119A1 (it) * 2002-03-05 2003-09-05 Geymonat Spa Composizioni contenenti plgf ad uso farmaceutico e cosmetico.
EP1962096B1 (fr) * 2002-11-16 2012-07-18 Siemens Healthcare Diagnostics Products GmbH SCD40L, PAPP-A et facteur de croissance placentaire (PIGF) en tant que combinaison de marqueurs biochimiques pour des maladies cardiovasculaires
EP2295449A1 (fr) 2009-09-09 2011-03-16 Dompe PHA.R.MA S.p.A. PLGF-1 sous forme homodimérique
WO2014117155A1 (fr) * 2013-01-28 2014-07-31 Shire Human Genetic Therapies, Inc. Facteur de croissance placentaire dans le traitement de la dystrophie musculaire de duchenne

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997014307A1 (fr) * 1995-10-20 1997-04-24 St. Elizabeth's Medical Center Of Boston, Inc. Procede de traitement des tissus ischemies
WO1998007832A1 (fr) * 1996-08-23 1998-02-26 Ludwig Institute For Cancer Research Facteur d recombinant de croissance des cellules endotheliales vasculaires (vegf-d)
WO1998049300A2 (fr) * 1997-04-25 1998-11-05 Collateral Therapeutics Formes tronquees de proteines apparentees au facteur vegf
GB2332373A (en) * 1997-12-19 1999-06-23 Merck & Co Inc Treatment of coronary and/or peripheral ischemia using an antithrombotic agent and an angiogenesis promoter
WO1999040197A2 (fr) * 1998-02-06 1999-08-12 Collateral Therapeutics, Inc. Variants du facteur angiogenique de croissance cellulaire endotheliale vasculaire vegf

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997014307A1 (fr) * 1995-10-20 1997-04-24 St. Elizabeth's Medical Center Of Boston, Inc. Procede de traitement des tissus ischemies
WO1998007832A1 (fr) * 1996-08-23 1998-02-26 Ludwig Institute For Cancer Research Facteur d recombinant de croissance des cellules endotheliales vasculaires (vegf-d)
WO1998049300A2 (fr) * 1997-04-25 1998-11-05 Collateral Therapeutics Formes tronquees de proteines apparentees au facteur vegf
GB2332373A (en) * 1997-12-19 1999-06-23 Merck & Co Inc Treatment of coronary and/or peripheral ischemia using an antithrombotic agent and an angiogenesis promoter
WO1999040197A2 (fr) * 1998-02-06 1999-08-12 Collateral Therapeutics, Inc. Variants du facteur angiogenique de croissance cellulaire endotheliale vasculaire vegf

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FRELIN C. ET AL.: "VEGF : a mediator of hypoxic angiogenesis", MEDECINE SCIENCES, vol. 13, no. 6-7, 1997, pages 886 - 890, XP001000433 *

Also Published As

Publication number Publication date
AU4643501A (en) 2001-08-14
PT1253935E (pt) 2006-08-31
DK1253935T3 (da) 2006-09-04
ATE324905T1 (de) 2006-06-15
WO2001056593A2 (fr) 2001-08-09
JP4969753B2 (ja) 2012-07-04
EP1253935A2 (fr) 2002-11-06
DE60119285D1 (de) 2006-06-08
WO2001057181A2 (fr) 2001-08-09
EP1253935B1 (fr) 2006-05-03
ES2263582T3 (es) 2006-12-16
JP2003521522A (ja) 2003-07-15
AU2001230243A1 (en) 2001-08-14
DE60119285T2 (de) 2007-05-10

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