WO2001054667A1 - Electrospun pharmaceutical compositions - Google Patents
Electrospun pharmaceutical compositions Download PDFInfo
- Publication number
- WO2001054667A1 WO2001054667A1 PCT/US2001/002399 US0102399W WO0154667A1 WO 2001054667 A1 WO2001054667 A1 WO 2001054667A1 US 0102399 W US0102399 W US 0102399W WO 0154667 A1 WO0154667 A1 WO 0154667A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- agent
- composition according
- poly
- active agent
- cellulose
- Prior art date
Links
Classifications
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- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0015—Electro-spinning characterised by the initial state of the material
- D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
- D01D5/0038—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0015—Electro-spinning characterised by the initial state of the material
- D01D5/0023—Electro-spinning characterised by the initial state of the material the material being a polymer melt
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F1/00—General methods for the manufacture of artificial filaments or the like
- D01F1/02—Addition of substances to the spinning solution or to the melt
- D01F1/10—Other agents for modifying properties
Abstract
Description
Claims
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01903299A EP1251829A4 (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions |
IL15064201A IL150642A0 (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions |
HU0301130A HUP0301130A3 (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions |
BR0107869-0A BR0107869A (en) | 2000-01-28 | 2001-01-25 | Electrogenated pharmaceutical compositions |
MXPA02007298A MXPA02007298A (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions. |
AU31134/01A AU772830B2 (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions |
CA002396640A CA2396640A1 (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions |
NZ519992A NZ519992A (en) | 2000-01-28 | 2001-01-25 | Pharmaceutical compositions containing electrospun fiber of polymeric carrier integrated with active agent |
PL01356924A PL356924A1 (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions |
JP2001555646A JP2003521493A (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical composition |
NO20023338A NO20023338L (en) | 2000-01-28 | 2002-07-11 | Electrical "spun" pharmaceutical preparations |
AU2004202461A AU2004202461B2 (en) | 2000-01-28 | 2004-06-03 | Electrospun pharmaceutical compositions |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17868200P | 2000-01-28 | 2000-01-28 | |
US60/178,682 | 2000-01-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001054667A1 true WO2001054667A1 (en) | 2001-08-02 |
Family
ID=22653497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/002399 WO2001054667A1 (en) | 2000-01-28 | 2001-01-25 | Electrospun pharmaceutical compositions |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1251829A4 (en) |
JP (1) | JP2003521493A (en) |
KR (1) | KR100806412B1 (en) |
CN (1) | CN1223340C (en) |
AR (1) | AR028204A1 (en) |
AU (1) | AU772830B2 (en) |
BR (1) | BR0107869A (en) |
CA (1) | CA2396640A1 (en) |
HU (1) | HUP0301130A3 (en) |
IL (1) | IL150642A0 (en) |
MX (1) | MXPA02007298A (en) |
MY (1) | MY129356A (en) |
NO (1) | NO20023338L (en) |
NZ (1) | NZ519992A (en) |
PL (1) | PL356924A1 (en) |
TW (1) | TWI289061B (en) |
WO (1) | WO2001054667A1 (en) |
ZA (1) | ZA200205989B (en) |
Cited By (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003030939A1 (en) * | 2001-10-05 | 2003-04-17 | Glaxo Group Limited | Therapies for treating respiratory diseases |
WO2003087443A1 (en) * | 2002-04-11 | 2003-10-23 | Secant Medical, Inc. | Covering process using electrospinning of very small fibers |
EP1377420A2 (en) * | 2001-03-20 | 2004-01-07 | Nicast Ltd. | Portable electrospinning device |
EP1534250A2 (en) * | 2002-08-07 | 2005-06-01 | SmithKline Beecham Corporation | Electrospun amorphous pharmaceutical compositions |
WO2006090150A1 (en) * | 2005-02-24 | 2006-08-31 | Smithkline Beecham Corporation | Pharmaceutical composition comprising amorphous rosiglitazone |
WO2007100466A2 (en) * | 2006-02-28 | 2007-09-07 | Elan Pharma International Ltd. | Nanoparticulate carvedilol formulations |
CN100457445C (en) * | 2001-05-16 | 2009-02-04 | 中国科学院化学研究所 | Biodegradable and/or biological absorbing fiber product and its use in medical application |
US7618579B2 (en) * | 2002-03-26 | 2009-11-17 | E.I. Du Pont De Nemours And Company | Manufacturing device and the method of preparing for the nanofibers via electro-blown spinning process |
WO2010015709A2 (en) | 2008-08-08 | 2010-02-11 | Basf Se | Fibrous surface structure containing active ingredients with controlled release of active ingredients, use thereof and method for the production thereof |
US7765647B2 (en) | 2002-04-04 | 2010-08-03 | The University Of Akron | Non-woven fiber assemblies |
US7842780B2 (en) | 2003-01-07 | 2010-11-30 | Trustees Of Tufts College | Silk fibroin materials and use thereof |
CN101915797A (en) * | 2010-07-27 | 2010-12-15 | 北京师范大学 | Method for preparing electrostatic spinning immobilized laccase electrode |
US20110045041A1 (en) * | 2008-03-27 | 2011-02-24 | Nevenka Golubovic-Liakopoulos | Compositions and methods for the delivery of agents |
WO2011029777A1 (en) | 2009-09-11 | 2011-03-17 | Basf Se | Methods for producing coated polymer fibers |
US7972622B1 (en) | 1999-05-06 | 2011-07-05 | Battelle (Memorial Institute) | Method and apparatus for manufacturing dissolvable tablets |
CN102251317A (en) * | 2011-05-18 | 2011-11-23 | 东华大学 | Preparation method of electrospun fibers with controllable drug release |
WO2012003350A1 (en) * | 2010-07-02 | 2012-01-05 | The Procter & Gamble Company | Methods of delivering a health care active by administering personal health care articles comprising a filament |
US20120058166A1 (en) * | 2010-07-02 | 2012-03-08 | Glenn Jr Robert Wayne | Filaments comprising a non-perfume active agent nonwoven webs and methods for making same |
WO2012084427A1 (en) | 2010-12-22 | 2012-06-28 | Unilever Nv | Compositions comprising structured non-aqueous liquid phase |
WO2012084441A1 (en) | 2010-12-22 | 2012-06-28 | Unilever Nv | Compositions in the form of fibres |
CN101721751B (en) * | 2008-10-10 | 2013-01-02 | 张阳德 | Human tissue engineering support loaded with controlled-release cell growth factor and provided with hollow silicon dioxide ball with kernel and preparation method and applications thereof |
US8367570B2 (en) | 2002-04-04 | 2013-02-05 | The University Of Akron | Mechanically strong absorbent non-woven fibrous mats |
CN102959150A (en) * | 2010-07-02 | 2013-03-06 | 宝洁公司 | Filaments comprising an ingestible active agent nonwoven webs and methods for making same |
WO2012003349A3 (en) * | 2010-07-02 | 2013-04-18 | The Procter & Gamble Company | Dissolvable fibrous web structure article comprising active agents |
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US8628706B2 (en) | 2008-04-16 | 2014-01-14 | The Procter & Gamble Company | Non-lathering personal care composition in the form of an article |
EP2684562A1 (en) | 2008-08-08 | 2014-01-15 | Basf Se | Fibre layer with an active substance on the basis of bio-polymers, applications of same and method for their manufacture |
US8785361B2 (en) | 2010-07-02 | 2014-07-22 | The Procter & Gamble Company | Detergent product and method for making same |
WO2014131376A1 (en) * | 2013-02-26 | 2014-09-04 | Elmarco S.R.O. | Electrospun nanofibers comprising pharmaceutically active agents |
US20140363484A1 (en) * | 2012-02-21 | 2014-12-11 | Amrita Vishwa Vidyapeetham | Fibrous bio-degradable polymeric wafers system for the local delivery of therapeutic agents in combinations |
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US8974823B2 (en) | 2003-12-31 | 2015-03-10 | Bend Research, Inc. | Solid compositions of low-solubility drugs and poloxamers |
US9023393B2 (en) | 2003-08-04 | 2015-05-05 | Bend Research, Inc. | Pharmaceutical compositions of adsorbates of amorphous drugs and lipophilic microphase-forming materials |
US9074305B2 (en) | 2010-07-02 | 2015-07-07 | The Procter & Gamble Company | Method for delivering an active agent |
US9163205B2 (en) | 2010-07-02 | 2015-10-20 | The Procter & Gamble Company | Process for making films from nonwoven webs |
US9173826B2 (en) | 2010-02-16 | 2015-11-03 | The Procter & Gamble Company | Porous, dissolvable solid substrate and surface resident coating comprising a zync pyrithione |
US9233055B2 (en) | 2012-10-12 | 2016-01-12 | The Procter & Gamble Company | Personal care composition in the form of a dissolvable article |
US9295859B2 (en) | 2009-12-08 | 2016-03-29 | The Procter & Gamble Company | Porous, dissolvable solid substrate and surface resident coating comprising matrix microspheres |
US9486410B2 (en) | 2002-02-01 | 2016-11-08 | Bend Research, Inc. | Pharmaceutical compositions of amorphous dispersions of drugs and lipophilic microphase-forming materials |
US9775917B2 (en) | 2013-03-12 | 2017-10-03 | Active Fibres Limited | Nanofibre and bioactive compositions and related methods |
US9808418B2 (en) | 2010-11-26 | 2017-11-07 | University Of The Witwatersrand, Johannesburg | Pharmaceutical dosage form |
US9827173B2 (en) | 2014-05-05 | 2017-11-28 | The Procter & Gamble Company | Porous dissolvable solid structure with two benefit agents and methods of forming an aqueous treatment liquor therefrom |
US9861558B2 (en) | 2014-05-05 | 2018-01-09 | The Procter & Gamble Company | Methods of forming an aqueous treatment liquor by dissolving a porous solid with a benefit agent coating |
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US9867762B2 (en) | 2014-05-05 | 2018-01-16 | The Procter & Gamble Company | Consumer product comprising a porous dissolvable solid structure and silicone conditioning agent coating |
US9877899B2 (en) | 2014-05-05 | 2018-01-30 | The Procter & Gamble Company | Consumer product comprising a fibrous web structure with a silicone conditioning agent coating |
US9937111B2 (en) | 2014-05-05 | 2018-04-10 | The Procter & Gamble Company | Consumer product comprising a fibrous web solid structure with a silicone conditioning agent coating |
US10202636B2 (en) | 2013-12-24 | 2019-02-12 | General Electric Company | Electrospun fibers for protein stabilization and storage |
US10717839B2 (en) | 2014-04-22 | 2020-07-21 | The Procter And Gamble Company | Compositions in the form of dissolvable solid structures |
US20210069122A1 (en) * | 2016-01-27 | 2021-03-11 | Instar Technologies A.S. | Oromucosal nanofiber carriers for therapeutic treatment |
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CN1223340C (en) | 2005-10-19 |
CA2396640A1 (en) | 2001-08-02 |
IL150642A0 (en) | 2003-02-12 |
NO20023338L (en) | 2002-09-03 |
AU3113401A (en) | 2001-08-07 |
NZ519992A (en) | 2004-04-30 |
EP1251829A1 (en) | 2002-10-30 |
NO20023338D0 (en) | 2002-07-11 |
HUP0301130A2 (en) | 2003-09-29 |
KR20020082212A (en) | 2002-10-30 |
AR028204A1 (en) | 2003-04-30 |
AU772830B2 (en) | 2004-05-06 |
MY129356A (en) | 2007-03-30 |
HUP0301130A3 (en) | 2006-07-28 |
EP1251829A4 (en) | 2009-05-06 |
PL356924A1 (en) | 2004-07-12 |
TWI289061B (en) | 2007-11-01 |
KR100806412B1 (en) | 2008-02-21 |
ZA200205989B (en) | 2003-02-03 |
MXPA02007298A (en) | 2002-12-09 |
BR0107869A (en) | 2002-11-05 |
JP2003521493A (en) | 2003-07-15 |
CN1396823A (en) | 2003-02-12 |
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