WO2001049273A3 - Composition pharmaceutique pour administration transdermique d'hormones avec un additif ameliorant la permeation - Google Patents

Composition pharmaceutique pour administration transdermique d'hormones avec un additif ameliorant la permeation Download PDF

Info

Publication number
WO2001049273A3
WO2001049273A3 PCT/EP2000/013268 EP0013268W WO0149273A3 WO 2001049273 A3 WO2001049273 A3 WO 2001049273A3 EP 0013268 W EP0013268 W EP 0013268W WO 0149273 A3 WO0149273 A3 WO 0149273A3
Authority
WO
WIPO (PCT)
Prior art keywords
additive
pharmaceutical composition
hormones
transdermally administering
enhances permeation
Prior art date
Application number
PCT/EP2000/013268
Other languages
German (de)
English (en)
Other versions
WO2001049273A2 (fr
Inventor
Achim Berthold
Original Assignee
Lohmann Therapie Syst Lts
Achim Berthold
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts, Achim Berthold filed Critical Lohmann Therapie Syst Lts
Priority to AU23698/01A priority Critical patent/AU2369801A/en
Publication of WO2001049273A2 publication Critical patent/WO2001049273A2/fr
Publication of WO2001049273A3 publication Critical patent/WO2001049273A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne une composition pharmaceutique d'administration transdermique d'une ou de plusieurs hormones, à fixer sur la peau, par adhérence, qui comprend au moins une couche matricielle contenant l'hormone. Cette composition pharmaceutique comprend un additif améliorant la perméation de la peau et se caractérise en ce que l'additif mentionné présente une structure de base 1,4-dioxane-2,5-dione de formule générale (I), les restes R1 et R2 étant des groupes hydrocarbures ou des groupes hydrocarbures substitués ou des groupes fonctionnels.
PCT/EP2000/013268 2000-01-07 2000-12-23 Composition pharmaceutique pour administration transdermique d'hormones avec un additif ameliorant la permeation WO2001049273A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU23698/01A AU2369801A (en) 2000-01-07 2000-12-23 Pharmaceutical composition for transdermally administering hormones with an additive that enhances permeation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10000333.8 2000-01-07
DE2000100333 DE10000333A1 (de) 2000-01-07 2000-01-07 Pharmazeutische Zusammensetzung zur transdermalen Verabreichung von Hormonen mit einem permeationsverbessernden Zusatzstoff

Publications (2)

Publication Number Publication Date
WO2001049273A2 WO2001049273A2 (fr) 2001-07-12
WO2001049273A3 true WO2001049273A3 (fr) 2002-05-23

Family

ID=7626866

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/013268 WO2001049273A2 (fr) 2000-01-07 2000-12-23 Composition pharmaceutique pour administration transdermique d'hormones avec un additif ameliorant la permeation

Country Status (4)

Country Link
AR (1) AR026797A1 (fr)
AU (1) AU2369801A (fr)
DE (1) DE10000333A1 (fr)
WO (1) WO2001049273A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873371B1 (fr) * 2004-07-26 2008-07-04 Sod Conseils Rech Applic Nouvelle methode de synthese de 2,5 dioxane 1,4 diones
DE102006050558B4 (de) 2006-10-26 2009-03-26 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution
DE102010004769A1 (de) 2009-07-08 2011-01-13 Kuchenbecker, Manfred, Dr.-Ing. Reluktanzgenerator
US9011832B2 (en) 2012-02-09 2015-04-21 Novus International, Inc. Heteroatom containing cyclic dimers
MX2015000395A (es) 2012-07-12 2015-04-10 Novus Int Inc Composiciones de matriz y capa para proteccion de bioactivos.
KR20160040206A (ko) 2013-08-09 2016-04-12 더 케무어스 컴퍼니 에프씨, 엘엘씨 환형 다이에스테르를 갖는 피부 케어 조성물 및 이의 방법
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996003119A1 (fr) * 1994-07-26 1996-02-08 Lavipharm S.A. Dispositif d'administration transdermique contenant un ×strogene
WO1996040087A2 (fr) * 1995-06-07 1996-12-19 Cygnus, Inc. Composition acrylique adhesive sensible a la pression reticulee avec de l'acetylacetonate d'aluminium et contenant un medicament qui renferme un groupe hydroxy aromatique reactif

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996003119A1 (fr) * 1994-07-26 1996-02-08 Lavipharm S.A. Dispositif d'administration transdermique contenant un ×strogene
WO1996040087A2 (fr) * 1995-06-07 1996-12-19 Cygnus, Inc. Composition acrylique adhesive sensible a la pression reticulee avec de l'acetylacetonate d'aluminium et contenant un medicament qui renferme un groupe hydroxy aromatique reactif

Also Published As

Publication number Publication date
AU2369801A (en) 2001-07-16
AR026797A1 (es) 2003-02-26
WO2001049273A2 (fr) 2001-07-12
DE10000333A1 (de) 2001-07-19

Similar Documents

Publication Publication Date Title
IL129318A0 (en) Use of 1-benzyl-3- (substituted hetaryl)- fused pyrazole derivatives
WO2004060405A3 (fr) Composes et compositions reagissant avec des tissus et utilisations associees
CA2258920A1 (fr) Acide hyaluronique autoreticule et compositions pharmaceutiques associees pour le traitement des arthropathies
GT200000137A (es) Pirimidina - 2, 4, 6 - trionas inhibidores de metaloproteinasas.
WO2005016286A3 (fr) Modulateurs pyraziniques de recepteurs canabinoïdes
UA41316C2 (uk) Трициклічні похідні піролу і фармацевтичний препарат
DK1162943T3 (da) Ikke-sviende coatingpræparat
DE69226624T2 (de) Zusammensetzung, die eine tramadol-verbindung und acetaminophen enthält, und ihre verwendung
ATE244558T1 (de) Trockene formbare arzneistoffformulierung
CY1105225T1 (el) Παραγωγα 5-β-σαπωγενινης και ψευδοσαπωγενινης και η χρηση τους στην αντιμετωπιση ανοιας
WO2004060315A3 (fr) Compositions stables pour une administration de medicament topique
BRPI0307777B8 (pt) emplastro transdérmico
WO2001049273A3 (fr) Composition pharmaceutique pour administration transdermique d'hormones avec un additif ameliorant la permeation
KR900005978A (ko) 키니딘, 아르테미시닌 및 이의 유도체를 사용한 항말라리아 조성물 및 치료방법
BR0215935A (pt) Terapia combinada para tratamento de leucemia aguda e sìndrome mielodisplásica
DK1135163T3 (da) Topiske sammensætninger indeholdende ascomyciner
ATE214803T1 (de) Stabilisierte standards und kalibratoren
PL320915A1 (en) Derivatives of piperasino-2,5-dione as modulators of drug-fasteness in respect to many drugs
ATE134294T1 (de) Zusammensetzung mit psyllium
BR8904152A (pt) Composicao,composicao curavel,verniz de laminacao,substrato,laminado e composicao de agente de cura
BG103728A (en) Derivatives of dolastatin-15 in combination with taxanes
DE69430797T2 (de) C9 taxanderivate und diese enthaltende pharmazeutische zusammensetzungen
ATE273985T1 (de) Ruthenium (ii) verbindungen in der krebsbehandlung
NO20042138L (no) Forbindelser og fremgangsmate for behandling av hyperaktiv blaere
DE69834468D1 (de) Mehrschichtstrukturen

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU BR CA CN JP KR MX US ZA

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AU BR CA CN JP KR MX US ZA

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP