WO2001036965A3 - Procede d'identification d'une matiere biochimique - Google Patents

Procede d'identification d'une matiere biochimique Download PDF

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Publication number
WO2001036965A3
WO2001036965A3 PCT/IB2000/001685 IB0001685W WO0136965A3 WO 2001036965 A3 WO2001036965 A3 WO 2001036965A3 IB 0001685 W IB0001685 W IB 0001685W WO 0136965 A3 WO0136965 A3 WO 0136965A3
Authority
WO
WIPO (PCT)
Prior art keywords
cellular material
container
fluid
detected
detection region
Prior art date
Application number
PCT/IB2000/001685
Other languages
English (en)
Other versions
WO2001036965A2 (fr
Inventor
Spiridon Kintzios
Original Assignee
Spiridon Kintzios
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spiridon Kintzios filed Critical Spiridon Kintzios
Priority to EP00979828A priority Critical patent/EP1366353A2/fr
Priority to IL14972800A priority patent/IL149728A0/xx
Priority to JP2001538802A priority patent/JP2003514539A/ja
Priority to AU17210/01A priority patent/AU1721001A/en
Publication of WO2001036965A2 publication Critical patent/WO2001036965A2/fr
Publication of WO2001036965A3 publication Critical patent/WO2001036965A3/fr

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Geophysics And Detection Of Objects (AREA)

Abstract

La présente invention concerne un procédé permettant d'indiquer la présence dans un liquide d'une matière à déceler, lequel procédé consiste: à mettre le liquide contenant la matière à déceler en contact avec une région de détection contenant une matière cellulaire; à surveiller une propriété électrique dans la région de détection; et à détecter la présence de la matière en détectant au moins une modification prédéterminée de la propriété électrique dans la région de détection. L'invention se rapporte également à un appareil permettant d'indiquer la présence dans un liquide d'une matière à déceler, qui comprend: un conteneur capable de contenir une matière cellulaire placée à l'intérieur d'une région prédéterminée dudit conteneur, ledit conteneur étant apte à mettre le liquide en contact avec une matière cellulaire contenue dans le conteneur; et un détecteur capable de détecter au moins une modification prédéterminée d'une propriété électrique dans la région prédéterminée.
PCT/IB2000/001685 1999-11-19 2000-11-16 Procede d'identification d'une matiere biochimique WO2001036965A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00979828A EP1366353A2 (fr) 1999-11-19 2000-11-16 Procede d'identification d'une matiere biochimique
IL14972800A IL149728A0 (en) 1999-11-19 2000-11-16 Method for identifying biochemical material
JP2001538802A JP2003514539A (ja) 1999-11-19 2000-11-16 生化学物質の同定方法
AU17210/01A AU1721001A (en) 1999-11-19 2000-11-16 Method for identifying biochemical material

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR990100398 1999-11-19
GR99100398 1999-11-19

Publications (2)

Publication Number Publication Date
WO2001036965A2 WO2001036965A2 (fr) 2001-05-25
WO2001036965A3 true WO2001036965A3 (fr) 2002-01-17

Family

ID=10943975

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2000/001685 WO2001036965A2 (fr) 1999-11-19 2000-11-16 Procede d'identification d'une matiere biochimique

Country Status (6)

Country Link
EP (1) EP1366353A2 (fr)
JP (1) JP2003514539A (fr)
AU (1) AU1721001A (fr)
GR (1) GR1003489B (fr)
IL (1) IL149728A0 (fr)
WO (1) WO2001036965A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9291549B2 (en) 2001-02-07 2016-03-22 Massachusetts Institute Of Technology Pathogen detection biosensor

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
EP1750129B1 (fr) 2001-02-07 2011-04-20 Massachusetts Institute of Technology Système de détection optoélectronique
GR1005420B (el) * 2006-01-20 2007-01-31 Σπυριδων Ευαγγελου Κιντζιος Μιμητικα κυτταρα
WO2010009307A2 (fr) * 2008-07-16 2010-01-21 Children's Medical Center Corporation Dispositif simulateur d’organe comportant des micro-canaux, procédés pour son utilisation et sa fabrication

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
DE19540098A1 (de) * 1995-10-27 1997-04-30 Inst Chemo Biosensorik Verfahren und Mehrkanalbiosensor zur Mehrkomponentenanalyse von Mischungen und/oder Gemischen
WO1997017426A1 (fr) * 1995-11-08 1997-05-15 Trustees Of Boston University Postes de travail pour physiologie cellulaire permettant une acquisition automatique des donnees et une gestion automatique des perfusions
WO1997049987A1 (fr) * 1996-06-27 1997-12-31 Cellstat Technologies, Inc. Procede et dispositif de criblage a haut rendement
WO1998023948A1 (fr) * 1996-11-29 1998-06-04 The Board Of Trustees Of The Leland Stanford Junior University Agencements de membranes a bicouches fluidiques supportees, adressables independamment, et procedes d'utilisation correspondants
WO1998054294A1 (fr) * 1997-05-30 1998-12-03 Board Of Trustees, Leland Stanford, Jr. University Biocapteur micro-electronique et technique de surveillance de cellules cultivees
WO1998055870A1 (fr) * 1997-06-04 1998-12-10 A+ Science Invest Ab Detection de molecules biologiquement actives a l'aide de capteurs biologiques pre-actives a base de cellule dans des systemes de separation a base de liquide

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
DE19540098A1 (de) * 1995-10-27 1997-04-30 Inst Chemo Biosensorik Verfahren und Mehrkanalbiosensor zur Mehrkomponentenanalyse von Mischungen und/oder Gemischen
WO1997017426A1 (fr) * 1995-11-08 1997-05-15 Trustees Of Boston University Postes de travail pour physiologie cellulaire permettant une acquisition automatique des donnees et une gestion automatique des perfusions
WO1997049987A1 (fr) * 1996-06-27 1997-12-31 Cellstat Technologies, Inc. Procede et dispositif de criblage a haut rendement
WO1998023948A1 (fr) * 1996-11-29 1998-06-04 The Board Of Trustees Of The Leland Stanford Junior University Agencements de membranes a bicouches fluidiques supportees, adressables independamment, et procedes d'utilisation correspondants
WO1998054294A1 (fr) * 1997-05-30 1998-12-03 Board Of Trustees, Leland Stanford, Jr. University Biocapteur micro-electronique et technique de surveillance de cellules cultivees
WO1998055870A1 (fr) * 1997-06-04 1998-12-10 A+ Science Invest Ab Detection de molecules biologiquement actives a l'aide de capteurs biologiques pre-actives a base de cellule dans des systemes de separation a base de liquide

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
IWATA M; KOMORI S; UNNO T; MINAMOTO N; OHASHI H: "Modification of membrane currents in mouse neuroblastoma cells following infection with rabies virus", BRITISH JOURNAL OF PHARMACOLOGY, vol. 126, April 1999 (1999-04-01), pages 1691 - 1698, XP000934183 *
MARTY J -L; LECA B; NOGUER T: "Biosensors for the detection of pesticides", ANALUSIS, vol. 26, July 1998 (1998-07-01) - August 1998 (1998-08-01), pages M144 - M149, XP000934103 *
RAWSON D M; WILLMER A J; TURNER A P F: "WHOLE-CELL BIOSENSORS FOR ENVIRONMENTAL MONITORING", BIOSENSORS, vol. 4, 1989, pages 299 - 312, XP000934099 *
SCHROTH P; SCHOENING M J; KORDOS P; LUETH H; SCHUETZ S; WEISSBECKER B; HUMMEL H E: "Insect-based BioFETs with improved signal characteristics", BIOSENSORS & BIOELECTRONICS, vol. 14, 15 March 1999 (1999-03-15), pages 303 - 308, XP000934104 *
SCHUETZ S; WEISSBECKER B; KOCH U T; HUMMEL H E: "Detection of volatiles released by diseased potato tubers using a biosensor on the basis of intact insect antennae", BIOSENSORS & BIOELECTRONICS, vol. 14, 1 February 1999 (1999-02-01), pages 221 - 228, XP000934109 *
WANG C ET AL: "Direct measurement of the influenza A virus M2 protein ion channel activity in mammalian cells", VIROLOGY,US,ACADEMIC PRESS,ORLANDO, vol. 205, no. 1, 1994, pages 133 - 140, XP002085469, ISSN: 0042-6822 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9291549B2 (en) 2001-02-07 2016-03-22 Massachusetts Institute Of Technology Pathogen detection biosensor

Also Published As

Publication number Publication date
AU1721001A (en) 2001-05-30
WO2001036965A2 (fr) 2001-05-25
IL149728A0 (en) 2002-11-10
JP2003514539A (ja) 2003-04-22
GR1003489B (el) 2000-11-30
EP1366353A2 (fr) 2003-12-03

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