WO2001023587A3 - Serine protease - Google Patents

Serine protease Download PDF

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Publication number
WO2001023587A3
WO2001023587A3 PCT/GB2000/003680 GB0003680W WO0123587A3 WO 2001023587 A3 WO2001023587 A3 WO 2001023587A3 GB 0003680 W GB0003680 W GB 0003680W WO 0123587 A3 WO0123587 A3 WO 0123587A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
hetaa37
polynucleotides
disclosed
methods
Prior art date
Application number
PCT/GB2000/003680
Other languages
French (fr)
Other versions
WO2001023587A2 (en
Inventor
Christopher Donald Southan
Original Assignee
Smithkline Beecham Plc
Christopher Donald Southan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc, Christopher Donald Southan filed Critical Smithkline Beecham Plc
Priority to EP00962730A priority Critical patent/EP1144654A3/en
Publication of WO2001023587A2 publication Critical patent/WO2001023587A2/en
Publication of WO2001023587A3 publication Critical patent/WO2001023587A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

HETAA37 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HETAA37 polypeptides and polynucleotides in the design of protocols for the treatment of cancer, inflammation, asthma, wasting diseases, atherosclerosis, stroke, diabetes, arthritis, Alzheimer's and other neurodegenerative diseases, and other neurological disorders, among others, and diagnostic assays for such conditions.
PCT/GB2000/003680 1999-09-25 2000-09-25 Serine protease WO2001023587A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP00962730A EP1144654A3 (en) 1999-09-25 2000-09-25 Serine protease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9922835.5A GB9922835D0 (en) 1999-09-25 1999-09-25 Novel compounds
GB9922835.5 1999-09-25

Publications (2)

Publication Number Publication Date
WO2001023587A2 WO2001023587A2 (en) 2001-04-05
WO2001023587A3 true WO2001023587A3 (en) 2001-10-11

Family

ID=10861681

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/003680 WO2001023587A2 (en) 1999-09-25 2000-09-25 Serine protease

Country Status (3)

Country Link
EP (1) EP1144654A3 (en)
GB (1) GB9922835D0 (en)
WO (1) WO2001023587A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6943236B2 (en) 1997-02-25 2005-09-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037418A2 (en) * 1997-02-25 1998-08-27 Corixa Corporation Compounds for immunodiagnosis of prostate cancer and methods for their use
EP0936270A2 (en) * 1998-02-12 1999-08-18 Basf Aktiengesellschaft Serin protease from prostate
US5955306A (en) * 1996-09-17 1999-09-21 Millenium Pharmaceuticals, Inc. Genes encoding proteins that interact with the tub protein

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955306A (en) * 1996-09-17 1999-09-21 Millenium Pharmaceuticals, Inc. Genes encoding proteins that interact with the tub protein
WO1998037418A2 (en) * 1997-02-25 1998-08-27 Corixa Corporation Compounds for immunodiagnosis of prostate cancer and methods for their use
EP0936270A2 (en) * 1998-02-12 1999-08-18 Basf Aktiengesellschaft Serin protease from prostate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PETER S NELSON ET AL: "Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,NATIONAL ACADEMY OF SCIENCE. WASHINGTON,US, vol. 96, no. 6, 16 March 1999 (1999-03-16), pages 3114 - 3119, XP002141959, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2001023587A2 (en) 2001-04-05
EP1144654A2 (en) 2001-10-17
EP1144654A3 (en) 2002-02-27
GB9922835D0 (en) 1999-11-24

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