WO2000026100A1 - Fermetures plastiques bactericides pour recipients a boissons - Google Patents

Fermetures plastiques bactericides pour recipients a boissons Download PDF

Info

Publication number
WO2000026100A1
WO2000026100A1 PCT/US1999/025046 US9925046W WO0026100A1 WO 2000026100 A1 WO2000026100 A1 WO 2000026100A1 US 9925046 W US9925046 W US 9925046W WO 0026100 A1 WO0026100 A1 WO 0026100A1
Authority
WO
WIPO (PCT)
Prior art keywords
closure
antibiotic
silver
zeolite
top wall
Prior art date
Application number
PCT/US1999/025046
Other languages
English (en)
Inventor
Amy Stahl
John E. Barry
Jeffrey A. Trogolo
Original Assignee
Agion Technologies L.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agion Technologies L.L.C. filed Critical Agion Technologies L.L.C.
Priority to AU11336/00A priority Critical patent/AU1133600A/en
Priority to CA002316840A priority patent/CA2316840A1/fr
Priority to EP19990955165 priority patent/EP1044139A4/fr
Publication of WO2000026100A1 publication Critical patent/WO2000026100A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/005—Closures provided with linings or internal coatings so as to avoid contact of the closure with the contents

Definitions

  • the present invention relates to containers, such as baby bottles and cups, used for drinking purposes and closures for these articles.
  • a particular object in this area would be to improve sanitary conditions of containers used by children and babies for drinking purposes.
  • Typical among these are, for example, plastic baby bottles and drinking cups.
  • a typical baby bottle includes the bottle container itself and a closure formed by a rubber nipple and a collar of plastic material having a hole into which the nipple is inserted, with the collar being fastened to the container.
  • Another typical type of such container is a plastic cup having a closure in the form of a lid with a spout, with the lid being screwed or snapped onto the cup.
  • the plastic collar and the lid forming the closures are often made by injection molding.
  • Bacterial growth sites also can be produced by other liquids, such as fruit juices, formula, and even water. When the user drinks liquid from the bottle or cup, the liquid can come into contact with the bacteria, which can be transferred to the user. Accordingly, it would be desirable to attempt to eliminate the growth of such bacteria on such products, that is to make the sites incapable or less capable of supporting bacterial growth.
  • the present invention relates to closures of the type described above containing an inorganic antimicrobial agent, preferably a ceramic zeolite.
  • the container closures such as the collar for the baby bottles and the lids for the cups, are made with the antimicrobial agent incorporated into the plastic resin used for molding the closures.
  • a further object is to provide closures for baby bottle and juvenile drinking containers having an antimicrobial agent.
  • Still a further object is to provide plastic closures for drinking containers containing an inorganic antimicrobial agent which reduce the possibility of establishment of bacterial growth sites.
  • Fig. 1 is a perspective view of a collar for a baby bottle
  • Fig. 1 A is a plan view of an insert of antimicrobial material for a baby bottle collar
  • Fig. 2 is a perspective view of a drinking container and a lid therefore;
  • Fig. 3 is a view of the underside of the lid of Fig 2 showing a modified version thereof.
  • Fig. 3A is a cross-section of a ridge used for the underside of the lid of Fig. 3.
  • Fig. 1 shows a collar 10 of the type used as a part of a closure for the open end of a baby bottle (not shown) .
  • the collar 1 0 has a top wall 1 2 with a hole 14 through which the end of the nipple (not shown) is inserted.
  • the collar has a depending skirt wall 1 6 with threads on the inner wall thereof which are used to fasten the collar to the bottle with the nipple inserted.
  • the collar 10 is made of a plastic material such as, for example, polypropylene, by any suitable process, such as injection molding.
  • the flange of the nipple is held between the top end the bottle and the top wall 1 2 of collar.
  • Fig. 2 shows a portion of a conventional type of drinking cup 20 used by children.
  • the cup has a threaded upper end 22 onto which the internally threaded wall 28 of a lid 30 is to be screwed.
  • the lid 30 has a spout 32 which the child places in his/her mouth, tips the cup and drinks from it.
  • the lids 20 also are of plastic and are typically made by injection molding.
  • the lid is normally only rinsed in tap water, such that a film is present on these surfaces which can support the growth of bacteria. This is a particular problem in the spout area, which is hard to clean.
  • the collar and lid components are made of material that has antimicrobial properties. It is preferred that the plastic resin used for forming the components contains an inorganic antimicrobial agent.
  • a preferred inorganic antimicrobial agent that can be incorporated into a resin suitable for the products is an antibiotic zeolite.
  • Suitable zeolites and a method for incorporating them into the resin is disclosed in U.S. patent 4,938,955.
  • the resins can be those such as polyethylene, polypropylene, polystyrene, polyvinyl chloride, ABS resins and others disclosed in said patent.
  • the zeolite is kneaded into the resin and the composite of the resin and the zeolite are then processed, such as by injection molding, to form the articles 1 0 and 20 described above.
  • the agent is available on the potential bacteria growth sites of the surfaces of the articles, including the interior of the spout 32, to prevent the growth of bacteria, such as would be caused by milk and other liquids coming into contact with it.
  • antimicrobial agents are also suitable as described below and would be processed in the same manner with the resin.
  • the inorganic antimicrobial agent incorporated in the resin a number of metal ions, which are inorganic materials, have been shown to possess antibiotic activity, including silver, copper, zinc, mercury, tin, lead, bismuth, cadmium, chromium and thallium ions. These antibiotic metal ions are believed to exert their effects by disrupting respiration and electron transport systems upon absorption into bacterial or fungal cells.
  • Antimicrobial metal ions of silver, gold, copper and zinc, in particular, are considered safe even for in vivo use. Antimicrobial silver ions are particularly useful for in vivo use due to the fact that they are not substantially absorbed into the body.
  • the inorganic antibiotic metal containing composition is an antibiotic metal salt.
  • antibiotic metal salts include silver iodate, silver iodide, silver nitrate, and silver oxide. Silver nitrate is preferred. These salts are particularly quick acting, as no release from ceramic particles is necessary for antimicrobial function.
  • Antibiotic zeolites are preferred. These have been prepared by replacing all or part of the ion-exchangeable ions in zeolite with ammonium ions and antibiotic metal ions, as described in U.S. Patent Nos. 4,938,958 and 4,91 1 ,898. Such zeolites have been incorporated in antibiotic resins (as shown in U.S.
  • Patent Nos. 4,938,955 and 4,906,464) and polymer articles U.S. Patent No. 4,775,585).
  • Polymers including the antibiotic zeolites have been used to make refrigerators, dish washers, rice cookers, plastic film, chopping boards, vacuum bottles, plastic pails, and garbage containers.
  • Other materials in which antibiotic zeolites have been incorporated include flooring, wall paper, cloth, paint, napkins, plastic automobile parts, catheters, bicycles, pens, toys, sand, and concrete. Examples of such uses are described in US Patents 5,714,445; 5,697,203; 5,562,872; 5,1 80,585; 5,714,430; and 5, 102,401 .
  • Antibiotic ceramic particles useful with the present invention include zeolites, hydroxy apatite, zirconium phosphates or other ion-exchange ceramics. Zeolites are preferred, and are described in the preferred embodiments referred to below. Hydroxy apatite particles containing antimicrobial metals are described, e.g., in U.S. Patent No. 5,009,898. Zirconium phosphates containing antimicrobial metals are described, e.g., in U.S. Patent Nos. 5,296,238; 5,441 ,71 7; and 5,405,644.
  • Antibiotic zeolites are well-known and can be prepared for use in the present invention using known methods. These include the antibiotic zeolites disclosed, for example, in U.S. Patent Nos. 4,938,958 and 4,91 1 ,898.
  • Zeolite is an aluminosilicate having a three dimensional skeletal structure that is represented by the formula: XM j /nO-Al j Oa-YSiO j -ZHjO.
  • M represents an ion-exchangeable ion, generally a monovalent or divalent metal ion
  • n represents the atomic valency of the (metal) ion
  • X and Y represent coefficients of metal oxide and silica respectively
  • Z represents the number of water of crystallization.
  • zeolites examples include A-type zeolites, X-type zeolites, Y-type zeolites, T-type zeolites, high-silica zeolites, sodalite, mordenite, analcite, clinoptilolite, chabazite and erionite.
  • the present invention is not restricted to use of these specific zeolites.
  • These ion-exchange capacities are sufficient for the zeolites to undergo ion-exchange with ammonium and antibiotic metal ions.
  • the specific surface area of preferred zeolite particles is preferably at least 1 50 m 2 /g (anhydrous zeolite as standard) and the SiO 2 /AI 2 O 3 mol ratio in the zeolite composition is preferably less than 14, more preferably less than 1 1 .
  • the antibiotic metal ions used in the antibiotic zeolites should be retained on the zeolite particles through an ion-exchange reaction.
  • Antibiotic metal ions which are adsorbed or attached without an ion-exchange reaction exhibit a decreased bacteriocidal effect and their antibiotic effect is not long-lasting. Nevertheless, it is advantageous for imparting quick antimicrobial action to maintain a sufficient amount of surface adsorbed metal ion.
  • the antibiotic metal ions tend to be converted into their oxides, hydroxides, basic salts etc. either in the micropores or on the surfaces of the zeolite and also tend to deposit there, particularly when the concentration of metal ions in the vicinity of the zeolite surface is high. Such deposition tends to adversely affect the bactericidal properties of ion-exchanged zeolite.
  • a relatively low degree of ion exchange is employed to obtain superior bactericidal properties.
  • the zeolite particles retain metal ions having bactericidal properties at ion-exchangeable sites of the zeolite in an amount less than the ion-exchange saturation capacity of the zeolite.
  • the zeolite employed in the present invention retains antimicrobial metal ions in an amount up to 41 % of the theoretical ion-exchange capacity of the zeolite.
  • Such ion-exchanged zeolite with a relatively low degree of ion-exchange may be prepared by performing ion-exchange using a metal ion solution having a low concentration as compared with solutions conventionally used for ion exchange.
  • the antibiotic metal ion is preferably present in the range of from about 0.1 to 20wt.% of the zeolite.
  • the zeolite contains from 0.1 to 20wt.% of silver ions and from 0.1 to 20wt.% of copper or ⁇ zinc ions.
  • ammonium ion can be contained in the zeolite at a concentration of about 20 wt.% or less of the zeolite, it is desirable to limit the content of ammonium ions to from 0.5 to 1 5 wt.%, preferably 1 .5 to 5 wt.%.
  • Weight% described herein is determined for materials dried at temperatures such as 1 10°C, 250°C or 550°C as this is the temperature employed for the preferred post-manufacturing drying process.
  • a preferred antibiotic zeolite is type A zeolite containing either a combination of ion-exchanged silver, zinc, and ammonium or silver and ammonium.
  • One such zeolite is manufactured by Shinegawa, Inc. under the product number AW-10N and consists of 0.6% by weight of silver ion-exchanged in Type A zeolite particles having a diameter of about 2.5 ⁇ .
  • Another formulation, AJ-10N consists of about 2% by weight silver ion-exchanged in Type A zeolite particles having a diameter of about 2.5 ;.
  • Another formulation, AW-80 contains 0.6% by weight of silver ion-exchanged in Type A zeolite particles having a. diameter of about 1 .0 ⁇ .
  • Another formulation, AJ-80N consists of about 2% by weight silver ion-exchanged in Type A zeolite particles having a diameter of about 1 .O ⁇ . These zeolites preferably contain about between 0.5% and 2.5% by weight of ion-exchanged ammonium.
  • the zeolites are often obtained in master batches of low density polyethylene, polypropylene, or polystyrene, containing 20 wt.% of the zeolite.
  • thermoplastic materials for forming the composite resin used to make the articles of the invention.
  • the antibiotic particles are preferably present in a concentration by weight in the resin used to make the articles of from 0.01 to 10.0 wt%, more preferably from 0.01 to 8.0 wt%, and most preferably from 0.1 to 5.0 wt%.
  • the antibiotic properties of the antibiotic zeolite particles of the invention may be assayed while in aqueous formulations using conventional assay techniques, including for example determining the minimum growth inhibitory concentration (MIC) with respect to a variety of bacteria, eumycetes and yeast. In such a test, the bacteria listed below may be employed: Bacillus cereus var mycoides,
  • Penicillum funiculosum Candida a/bicans
  • the assay for determining MIC can be carried out by smearing a solution containing bacteria for inoculation onto a plate culture medium to which a test sample of the encapsulated antibiotic zeolite particles is added in a particular concentration, followed by incubation and culturing of the plate.
  • the MIC is defined as a minimum concentration thereof required for inhibiting the growth of each bacteria.
  • the antibiotic zeolites are exceptionally suitable under relevant toxicity and biocompatibility standards for use in the articles and are not adversely affected or deteriorated upon being contacted by beverages such as milk and fruit juices.
  • Fig. 1 A shows a product useful with a baby bottle in the form of an annular disk 50 having a central hole 52 made from the resin and antimicrobial agent mixture.
  • the mixture is formed into flat sheets which are then cut or punched to the desired shape.
  • the disks 50 also can be made by extrusion or other conventional processes.
  • the disk 50 is inserted against the inner surface of the collar upper wall 1 4.
  • the agent present in the disk performs the function of preventing bacteria growth, as explained above.
  • Fig. 3 shows the inner surface 35 of the lid 30 as having a plurality of ridges 37 disposed thereon.
  • the ridges 37 increase the available surface area of the antibiotic agent.
  • Fig. 3A shows the ridges 37 as being of generally triangular shape, although other suitable shapes can be used.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne une fermeture pour un récipient destiné à contenir des liquides, cette fermeture étant fabriquée à base d'une résine contenant un agent inorganique bactéricide pouvant entrer en contact avec le liquide.
PCT/US1999/025046 1998-10-29 1999-10-25 Fermetures plastiques bactericides pour recipients a boissons WO2000026100A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU11336/00A AU1133600A (en) 1998-10-29 1999-10-25 Antimicrobial plastic closures for drinking containers
CA002316840A CA2316840A1 (fr) 1998-10-29 1999-10-25 Fermetures plastiques bactericides pour recipients a boissons
EP19990955165 EP1044139A4 (fr) 1998-10-29 1999-10-25 Fermetures plastiques bactericides pour recipients a boissons

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18214698A 1998-10-29 1998-10-29
US09/182,146 1998-10-29

Publications (1)

Publication Number Publication Date
WO2000026100A1 true WO2000026100A1 (fr) 2000-05-11

Family

ID=22667251

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/025046 WO2000026100A1 (fr) 1998-10-29 1999-10-25 Fermetures plastiques bactericides pour recipients a boissons

Country Status (4)

Country Link
EP (1) EP1044139A4 (fr)
AU (1) AU1133600A (fr)
CA (1) CA2316840A1 (fr)
WO (1) WO2000026100A1 (fr)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000052088A1 (fr) * 1999-03-01 2000-09-08 Agion Technologies, Llc Plateau antimicrobien
WO2004018020A1 (fr) 2002-08-21 2004-03-04 Hill-Rom Services, Inc. Pansement permettant d'empecher une blessure de se refermer
US6755807B2 (en) 1999-11-29 2004-06-29 Hill-Rom Services, Inc. Wound treatment apparatus
WO2008109442A2 (fr) * 2007-03-02 2008-09-12 Rubbermaid Commercial Products Llc Station de changement
EP2394931A1 (fr) 2010-06-10 2011-12-14 S.M.P. S.r.l. Conteneur et fermeture pour produits stérilisés ou à faible teneur en bactéries sans conservateurs
US8276229B2 (en) 2008-08-06 2012-10-02 Bobrick Washroom Equipment, Inc. Baby changing station
US8375490B2 (en) 2008-08-06 2013-02-19 Bobrick Washroom Equipment, Inc. Baby changing station
US8834520B2 (en) 2007-10-10 2014-09-16 Wake Forest University Devices and methods for treating spinal cord tissue
EP2801388A1 (fr) 2000-11-29 2014-11-12 KCI Medical Resources Therapie par le vide et pansement de nettoyage destine a des plaies
US9050136B2 (en) 2006-11-17 2015-06-09 Wake Forest University Health Sciences External fixation assembly and method of use
US9289193B2 (en) 2008-07-18 2016-03-22 Wake Forest University Health Sciences Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
BE1023272B1 (nl) * 2015-07-14 2017-01-19 Bepori Bvba Samenstelling van bacteriedodend rubber en gebruik in de veeteelt.
US9737455B2 (en) 2007-01-10 2017-08-22 Wake Forest Univeristy Health Sciences Apparatus and method for wound treatment employing periodic sub-atmospheric pressure
US10357404B2 (en) 2000-11-29 2019-07-23 Kci Medical Resources Unlimited Company Vacuum therapy and cleansing dressing for wounds
US10524598B2 (en) 2016-05-03 2020-01-07 Benny Green Easily cleanable drinking assembly
US10919672B2 (en) 2008-03-31 2021-02-16 Angelcare Feeding Usa, Llc Seal indication mechanism for containers
USRE48480E1 (en) 2008-08-06 2021-03-23 Bobrick Washroom Equipment, Inc. Baby changing station
IT201900022509A1 (it) * 2019-11-29 2021-05-29 Getters Spa Imballaggio alimentare per il controllo o la rimozione di ammine

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* Cited by examiner, † Cited by third party
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US4485064A (en) * 1982-04-06 1984-11-27 Baxter Travenol Laboratories, Inc. Antibacterial seal
US4775585A (en) 1983-01-21 1988-10-04 Kanebo Ltd./Kanto Chemical Co. Polymer article having an antibacterial property containing zeolite particles therein and the processes for producing same
US4906464A (en) 1987-12-26 1990-03-06 Shinagawa Fuel Co., Ltd. Method for preparing dispersions containing antibiotic power
US4938955A (en) 1987-04-22 1990-07-03 Shingawa Fuel Co., Ltd Antibiotic resin composition
US4938958A (en) 1986-12-05 1990-07-03 Shinagawa Fuel Co., Ltd. Antibiotic zeolite
US5009898A (en) 1988-09-29 1991-04-23 Kabushiki Kaisha Sangi Antimicrobial hydroxyapatite powders and methods for preparing them
US5102401A (en) 1990-08-22 1992-04-07 Becton, Dickinson And Company Expandable catheter having hydrophobic surface
US5180585A (en) 1991-08-09 1993-01-19 E. I. Du Pont De Nemours And Company Antimicrobial compositions, process for preparing the same and use
US5296238A (en) 1991-02-26 1994-03-22 Toagosei Chemical Industry Co., Inc. Microbicides
US5405644A (en) 1992-11-17 1995-04-11 Toagosei Chemical Industry Co., Ltd. Process for producing antimicrobial fiber
US5441717A (en) 1992-05-21 1995-08-15 Toagosei Chemical Industry Co., Inc., Ltd. Process for producing antimicrobial compounds
US5542557A (en) * 1991-05-09 1996-08-06 Toyo Seikan Kaisha, Ltd. Container closure wth liner and method of producing the same
US5562872A (en) 1993-02-16 1996-10-08 Daikyo Co., Ltd. A method for manufacturing an antibacterial chopping board
US5697203A (en) 1992-05-20 1997-12-16 Hachiku Shoji Kabushikikaisha Production unit of long-term preservable lunch and lunch box used for said lunch
US5714445A (en) 1993-03-31 1998-02-03 The Procter & Gamble Company Articles containing small particle size cyclodextrin for odor control
US5714430A (en) 1994-07-16 1998-02-03 Basf Aktiengesellschaft Mixtures containing fine metallic silver particles on a neutral to basic non-zeolite carrier oxide

Patent Citations (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485064A (en) * 1982-04-06 1984-11-27 Baxter Travenol Laboratories, Inc. Antibacterial seal
US4775585A (en) 1983-01-21 1988-10-04 Kanebo Ltd./Kanto Chemical Co. Polymer article having an antibacterial property containing zeolite particles therein and the processes for producing same
US4911898A (en) 1983-01-21 1990-03-27 Kanebo Limited Zeolite particles retaining silver ions having antibacterial properties
US4938958A (en) 1986-12-05 1990-07-03 Shinagawa Fuel Co., Ltd. Antibiotic zeolite
US4938955A (en) 1987-04-22 1990-07-03 Shingawa Fuel Co., Ltd Antibiotic resin composition
US4906464A (en) 1987-12-26 1990-03-06 Shinagawa Fuel Co., Ltd. Method for preparing dispersions containing antibiotic power
US5009898A (en) 1988-09-29 1991-04-23 Kabushiki Kaisha Sangi Antimicrobial hydroxyapatite powders and methods for preparing them
US5102401A (en) 1990-08-22 1992-04-07 Becton, Dickinson And Company Expandable catheter having hydrophobic surface
US5296238A (en) 1991-02-26 1994-03-22 Toagosei Chemical Industry Co., Inc. Microbicides
US5542557A (en) * 1991-05-09 1996-08-06 Toyo Seikan Kaisha, Ltd. Container closure wth liner and method of producing the same
US5180585A (en) 1991-08-09 1993-01-19 E. I. Du Pont De Nemours And Company Antimicrobial compositions, process for preparing the same and use
US5697203A (en) 1992-05-20 1997-12-16 Hachiku Shoji Kabushikikaisha Production unit of long-term preservable lunch and lunch box used for said lunch
US5441717A (en) 1992-05-21 1995-08-15 Toagosei Chemical Industry Co., Inc., Ltd. Process for producing antimicrobial compounds
US5405644A (en) 1992-11-17 1995-04-11 Toagosei Chemical Industry Co., Ltd. Process for producing antimicrobial fiber
US5562872A (en) 1993-02-16 1996-10-08 Daikyo Co., Ltd. A method for manufacturing an antibacterial chopping board
US5714445A (en) 1993-03-31 1998-02-03 The Procter & Gamble Company Articles containing small particle size cyclodextrin for odor control
US5714430A (en) 1994-07-16 1998-02-03 Basf Aktiengesellschaft Mixtures containing fine metallic silver particles on a neutral to basic non-zeolite carrier oxide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1044139A4 *

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000052088A1 (fr) * 1999-03-01 2000-09-08 Agion Technologies, Llc Plateau antimicrobien
US6755807B2 (en) 1999-11-29 2004-06-29 Hill-Rom Services, Inc. Wound treatment apparatus
US10357404B2 (en) 2000-11-29 2019-07-23 Kci Medical Resources Unlimited Company Vacuum therapy and cleansing dressing for wounds
EP2801388A1 (fr) 2000-11-29 2014-11-12 KCI Medical Resources Therapie par le vide et pansement de nettoyage destine a des plaies
EP2545946A2 (fr) 2002-08-21 2013-01-16 KCI Medical Resources Pansement permettant d'empêcher une blessure de se refermer
WO2004018020A1 (fr) 2002-08-21 2004-03-04 Hill-Rom Services, Inc. Pansement permettant d'empecher une blessure de se refermer
EP3181178A1 (fr) 2002-08-21 2017-06-21 KCI Medical Resources Pansement permettant d'empêcher une plaie de se refermer
US9050136B2 (en) 2006-11-17 2015-06-09 Wake Forest University Health Sciences External fixation assembly and method of use
US9737455B2 (en) 2007-01-10 2017-08-22 Wake Forest Univeristy Health Sciences Apparatus and method for wound treatment employing periodic sub-atmospheric pressure
US8079104B2 (en) 2007-03-02 2011-12-20 Rubbermaid Commercial Products/Us Changing station
WO2008109442A3 (fr) * 2007-03-02 2008-10-30 Rubbermaid Commercial Products Station de changement
WO2008109442A2 (fr) * 2007-03-02 2008-09-12 Rubbermaid Commercial Products Llc Station de changement
US8099810B2 (en) 2007-03-02 2012-01-24 Rubbermaid Commercial Products Llc Changing station
US8834520B2 (en) 2007-10-10 2014-09-16 Wake Forest University Devices and methods for treating spinal cord tissue
US10919672B2 (en) 2008-03-31 2021-02-16 Angelcare Feeding Usa, Llc Seal indication mechanism for containers
US10076318B2 (en) 2008-07-18 2018-09-18 Wake Forest University Health Sciences Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
US9289193B2 (en) 2008-07-18 2016-03-22 Wake Forest University Health Sciences Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
US8276229B2 (en) 2008-08-06 2012-10-02 Bobrick Washroom Equipment, Inc. Baby changing station
US8375490B2 (en) 2008-08-06 2013-02-19 Bobrick Washroom Equipment, Inc. Baby changing station
US8365328B2 (en) 2008-08-06 2013-02-05 Bobrick Washroom Equipment, Inc. Baby changing station
USRE47163E1 (en) 2008-08-06 2018-12-18 Bobrick Washroom Equipment, Inc. Baby changing station
USRE48480E1 (en) 2008-08-06 2021-03-23 Bobrick Washroom Equipment, Inc. Baby changing station
EP2394931A1 (fr) 2010-06-10 2011-12-14 S.M.P. S.r.l. Conteneur et fermeture pour produits stérilisés ou à faible teneur en bactéries sans conservateurs
BE1023272B1 (nl) * 2015-07-14 2017-01-19 Bepori Bvba Samenstelling van bacteriedodend rubber en gebruik in de veeteelt.
US10524598B2 (en) 2016-05-03 2020-01-07 Benny Green Easily cleanable drinking assembly
IT201900022509A1 (it) * 2019-11-29 2021-05-29 Getters Spa Imballaggio alimentare per il controllo o la rimozione di ammine
WO2021105065A1 (fr) 2019-11-29 2021-06-03 Saes Getters S.P.A. Emballage alimentaire pour la régulation ou l'élimination d'amines
CN114728734A (zh) * 2019-11-29 2022-07-08 工程吸气公司 用于胺控制或去除的食品包装
CN114728734B (zh) * 2019-11-29 2023-04-11 工程吸气公司 用于胺控制或去除的食品包装
US11772070B2 (en) 2019-11-29 2023-10-03 Saes Getters S.P.A. Food package for amines control or removal

Also Published As

Publication number Publication date
AU1133600A (en) 2000-05-22
EP1044139A4 (fr) 2002-11-06
EP1044139A1 (fr) 2000-10-18
CA2316840A1 (fr) 2000-05-11

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