WO2000021463A1 - Devices and methods for use in performing transmyocardial coronary bypass - Google Patents

Devices and methods for use in performing transmyocardial coronary bypass Download PDF

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Publication number
WO2000021463A1
WO2000021463A1 PCT/US1999/022954 US9922954W WO0021463A1 WO 2000021463 A1 WO2000021463 A1 WO 2000021463A1 US 9922954 W US9922954 W US 9922954W WO 0021463 A1 WO0021463 A1 WO 0021463A1
Authority
WO
WIPO (PCT)
Prior art keywords
heart
support
wall
expanded
orientation
Prior art date
Application number
PCT/US1999/022954
Other languages
English (en)
French (fr)
Other versions
WO2000021463A9 (en
Inventor
Darin C. Gittings
A. Adam Sharkawy
Alan R. Rapacki
Gilbert S. Laroya
Original Assignee
Ventrica, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventrica, Inc. filed Critical Ventrica, Inc.
Priority to AU65067/99A priority Critical patent/AU6506799A/en
Priority to EP99953035A priority patent/EP1121067A1/de
Priority to CA002347457A priority patent/CA2347457A1/en
Priority to JP2000575445A priority patent/JP2002527141A/ja
Publication of WO2000021463A1 publication Critical patent/WO2000021463A1/en
Publication of WO2000021463A9 publication Critical patent/WO2000021463A9/en
Priority to AU2003234967A priority patent/AU2003234967A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/064Blood vessels with special features to facilitate anastomotic coupling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2493Transmyocardial revascularisation [TMR] devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure

Definitions

  • the invention relates to treating heart disease, and more particularly systems, devices and methods for reestablishing or improving blood flow to the myocardium.
  • Coronary artery disease is currently treated by interventional procedures such as percutaneous transluminal coronary angioplasty (PTC A), atherectomy and intracoronary stenting, as well as surgical procedures including coronary artery bypass grafting (CABG).
  • PTC A percutaneous transluminal coronary angioplasty
  • CABG coronary artery bypass grafting
  • the goal of these procedures is to reestablish or improve blood flow through occluded (or partially occluded) coronary arteries, which is accomplished, for example, by enlarging the blood flow lumen of the artery or by forming a bypass that allows blood to circumvent the occlusion.
  • What procedure(s) is used typically depends on the severity and location of the blockages. When successful, these procedures restore blood flow to myocardial tissue that had not been sufficiently perfused due to the occlusion.
  • the invention provides a device and method for engaging tissue of a coronary vessel or heart wall during a cardiovascular procedure.
  • a device constructed according to this embodiment includes first and second members coupled together so as to permit relative movement.
  • a tissue engaging mechanism is coupled to the first and second members and moves between first and second positions. In the preferred embodiment, the first and second positions are collapsed and expanded orientations.
  • the tissue engaging mechanism includes at least one tissue engaging member that contacts engage body tissue when in the expanded orientation.
  • a method carried out according to this embodiment includes steps of providing a tissue support device having a tissue engaging mechanism configured to assume an expanded, tissue supporting orientation, positioning the tissue support device through the wall of a patient's heart and locating the tissue engaging mechanism adjacent tissue, and placing the tissue engaging mechanism in the expanded, tissue supporting orientation in engagement with the tissue.
  • the invention provides a device and method for supporting a wall of a vascular structure in order to access the lumen of the vascular structure.
  • a device constructed according to this embodiment includes a support structure adapted to be positioned in the lumen of a vascular structure, the support structure comprising a plurality of support elements coupled together so as to be movable relative to each other. The support elements move relative to each other to move the support structure from a collapsed orientation to an expanded orientation in order to support a wall of a vascular structure, and are sized and configured so that when the support structure is in the expanded orientation the support elements engage the wall of the vascular structure to prevent the wall from collapsing.
  • Another device constructed according to this embodiment includes an introducer having a hollow interior and an elongated support member configured to be generally coiled when in an unbiased orientation and generally straight when in a biased orientation.
  • the interior of the introducer is sized and configured to receive the elongated support member and hold the support member in the generally straight, biased orientation.
  • the elongated support member is moved from the straight, biased orientation within the interior of the introducer to the coiled, unbiased orientation upon entering the interior of the vascular structure to support the vascular structure.
  • a method carried out according to this embodiment includes steps of positioning a support within an interior of a vascular structure such that the support contacts and supports a wall of the vascular structure, and introducing a medical device into the interior of the vascular structure by passing the device through the wall of the vascular structure and through the support.
  • the invention provides a device and method for stabilizing an area of a patient's heart adjacent a coronary vessel.
  • a device constructed according to this embodiment includes a base configured to be positioned adjacent a coronary vessel of a patient's heart, the base having at least one opening for accessing the coronary vessel.
  • At least one tissue engaging element is coupled to the base so as to be movable with respect to the base, the tissue engaging element having a portion configured to securely engage the wall of a patient's heart in order to stabilize the wall of the heart upon moving the tissue engaging element with respect to the base.
  • An actuator is provided for imparting relative movement to the base and the tissue engaging element in order to stabilize the heart while accessing the coronary vessel through the opening in the base.
  • the invention provides a conduit for placing a coronary vessel of a patient's heart in communication with a heart chamber.
  • the conduit is in the form of a tubular element including first and second portions having different cross-sectional sizes and a bore defining a blood flow path.
  • the cross-section of the first portion of the tubular element is larger than the cross-section of the second portion such that the tubular element is generally funnel-shaped, and the first and second portions of the tubular element are generally aligned so that the bore defines a generally straight blood flow path.
  • the invention provides a conduit for communicating a chamber of a patient's heart with a coronary vessel.
  • the conduit is in the form of an expandable stent including first and second portions having different cross- sectional sizes when the stent is expanded.
  • Each of the first and second portions of the stent includes strut members disposed along a first direction when the stent is unexpended and along a second direction when the stent is expanded, the second direction being transverse to the first direction.
  • the strut members of the first portion are longer than the strut members of the second portion so that the stent is generally funnel-shaped when expanded.
  • the invention provides a conduit is in the form of an expandable tubular element having first and second portions with different cross- sectional sizes.
  • This tubular element is preferably a coronary stent constructed so that the first and second portions are disposed in an orientation that provides the stent with maximum radial strength when expanded.
  • the invention provides a conduit for placing a coronary vessel in communication with a heart chamber, the conduit including a vessel support mechanism configured to contact and support the vessel wall when the conduit is positioned in the heart wall.
  • Fig. 1 is a schematic view of a patient prepared to undergo a cardiovascular surgical procedure, the patient's heart being exposed via a retractor positioned in a thoracotomy formed in the patient's chest;
  • Fig. 2 is a perspective view of the heart shown in Fig. 1, wherein a portion of the heart wall is broken away for clarity;
  • FIG. 2 A is an enlarged view of a portion of Fig. 2;
  • Figs. 3A-3B are perspective views showing a tissue engaging device constructed according to one embodiment of the invention, the device being shown in collapsed and expanded orientations, respectively;
  • Figs. 4A-4B are elevation views, in section, illustrating one preferred construction of a tissue engaging device according to the embodiment of Figs. 3A-3B, wherein the device is shown being used to engage the heart wall shown in Figs. 2-2A;
  • Figs. 5A-5B are elevation views, in section, illustrating another preferred construction of a tissue engaging device according to the embodiment of Figs. 3A-3B, wherein the device is shown being used to engage the heart wall shown in Figs. 2-2A;
  • Figs. 6A-6C are elevation views, in section, sequentially illustrating a vessel support device constructed according to another embodiment of the invention being used to support the wall of a vascular structure;
  • Fig. 7 is a perspective view of a vessel support device constructed according to an alternative embodiment of the invention, the device being shown positioned in the interior of a vascular structure;
  • Figs. 8A-8B are elevation views, in section, sequentially illustrating the device shown in Fig. 7 being used to support a coronary artery of the heart shown in Figs. 2-2A;
  • Fig. 9 is a perspective view of a vessel support device constructed according to another alternative embodiment of the invention, the device being shown positioned in the interior of a vascular structure;
  • Figs. 10A-10B are elevation views, in section, sequentially illustrating the device shown in Fig. 9 being used to support a coronary artery of the heart shown in Figs. 2-2A;
  • Figs. 11 A-l IB are plan views of a tissue engaging device constructed according to another embodiment of the invention, wherein the device is shown engaging the wall of the heart shown in Figs. 2-2 A in non-retracting and retracting orientations, respectively;
  • Figs. 12A-12B are elevation views, in section, taken along lines A- A in Figs. 11 A-l IB;
  • Fig. 13 is an elevation view, in section, of an alternative tissue engaging device constructed according to the embodiment shown in Figs. 12A-12B;
  • Figs. 14A-14B are elevation views of a tapered balloon forming part of another embodiment of the invention, wherein the balloon is shown in its collapsed and expanded orientations, respectively;
  • Figs. 15A-15B are elevation views of an expandable conduit mounted on the tapered balloon shown in Figs. 14A-14B, the conduit being shown in its collapsed and expanded orientations, respectively;
  • Fig. 16 is an elevation view, in section, of a portion of a heart wall and coronary vessel in which the conduit shown in Fig. 15A-15B has been positioned;
  • FIGs. 17A-17B are elevation views showing a conduit constructed according to still another embodiment of the invention, wherein the conduit has a cross- sectional size that varies over its length;
  • Fig. 18 is a perspective view of another embodiment of the invention providing a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel;
  • FIGS. 19A-19C are schematic representations of a preferred application for the conduit shown in Fig. 18;
  • Fig. 20 is a perspective view of an alternative embodiment of a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel;
  • Fig. 21 is a perspective view of another alternative embodiment of a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel;
  • Fig. 22 is a perspective view of yet another alternative embodiment of a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel.
  • Fig. 1 is a schematic view of a patient prepared to undergo a cardiovascular surgical procedure, the patient's heart being exposed via a retractor positioned in a thoracotomy formed in the patient's chest;
  • Fig. 2 is a perspective view of the heart shown in Fig. 1, wherein a portion of the heart wall is broken away for clarity;
  • FIG. 2A is an enlarged view of a portion of Fig. 2;
  • Figs. 3A-3B are perspective views showing a tissue engaging device constructed according to one embodiment of the invention, the device being shown in collapsed and expanded orientations, respectively;
  • Figs. 4A-4B are elevation views, in section, illustrating one preferred construction of a tissue engaging device according to the embodiment of Figs. 3A-3B, wherein the device is shown being used to engage the heart wall shown in Figs. 2-2A;
  • Figs. 5A-5B are elevation views, in section, illustrating another preferred construction of a tissue engaging device according to the embodiment of Figs. 3A-3B, wherein the device is shown being used to engage the heart wall shown in Figs. 2-2A;
  • Figs. 6A-6C are elevation views, in section, sequentially illustrating a vessel support device constructed according to another embodiment of the invention being used to support the wall of a vascular structure;
  • Fig. 7 is a perspective view of a vessel support device constructed according to an alternative embodiment of the invention, the device being shown positioned in the interior of a vascular structure;
  • Figs. 8A-8B are elevation views, in section, sequentially illustrating the device shown in Fig. 7 being used to support a coronary artery of the heart shown in Figs. 2-2A;
  • Fig. 9 is a perspective view of a vessel support device constructed according to another alternative embodiment of the invention, the device being shown positioned in the interior of a vascular structure;
  • Figs. 10A-10B are elevation views, in section, sequentially illustrating the device shown in Fig. 9 being used to support a coronary artery of the heart shown in Figs. 2-2A;
  • Figs. 11A-1 IB are plan views of a tissue engaging device constructed according to another embodiment of the invention, wherein the device is shown engaging the wall of the heart shown in Figs. 2-2 A in non-retracting and retracting orientations, respectively;
  • Figs. 12A-12B are elevation views, in section, taken along lines A-A in Figs. 11 A-l IB;
  • Fig. 13 is an elevation view, in section, of an alternative tissue engaging device constructed according to the embodiment shown in Figs. 12A-12B;
  • Figs. 14A-14B are elevation views of a tapered balloon forming part of another embodiment of the invention, wherein the balloon is shown in its collapsed and expanded orientations, respectively;
  • Figs. 15A-15B are elevation views of an expandable conduit mounted on the tapered balloon shown in Figs. 14A-14B, the conduit being shown in its collapsed and expanded orientations, respectively;
  • Fig. 16 is an elevation view, in section, of a portion of a heart wall and coronary vessel in which the conduit shown in Fig. 15A-15B has been positioned;
  • FIGs. 17A-17B are elevation views showing a conduit constructed according to still another embodiment of the invention, wherein the conduit has a cross- sectional size that varies over its length;
  • Fig. 18 is a perspective view of another embodiment of the invention providing a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel;
  • Figs. 19A-19C are schematic representations of a preferred application for the conduit shown in Fig. 18;
  • Fig. 20 is a perspective view of an alternative embodiment of a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel;
  • Fig. 21 is a perspective view of another alternative embodiment of a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel;
  • Fig. 22 is a perspective view of yet another alternative embodiment of a conduit for placing a coronary vessel in communication with a heart chamber while internally supporting the interior of the vessel.

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  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
PCT/US1999/022954 1998-10-13 1999-10-12 Devices and methods for use in performing transmyocardial coronary bypass WO2000021463A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU65067/99A AU6506799A (en) 1998-10-13 1999-10-12 Devices and methods for use in performing transmyocardial coronary bypass
EP99953035A EP1121067A1 (de) 1998-10-13 1999-10-12 Vorrichtungen und methoden zur durchführung eines transmyokardialen koronarbypasses
CA002347457A CA2347457A1 (en) 1998-10-13 1999-10-12 Devices and methods for use in performing transmyocardial coronary bypass
JP2000575445A JP2002527141A (ja) 1998-10-13 1999-10-12 心筋を横切る冠状動脈バイパスの実施における使用のためのデバイスおよび方法
AU2003234967A AU2003234967A1 (en) 1998-10-13 2003-08-14 Devices and methods for use in performing transmyocardial coronary bypass

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17209898A 1998-10-13 1998-10-13
US09/172,098 1998-10-13

Publications (2)

Publication Number Publication Date
WO2000021463A1 true WO2000021463A1 (en) 2000-04-20
WO2000021463A9 WO2000021463A9 (en) 2000-09-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/022954 WO2000021463A1 (en) 1998-10-13 1999-10-12 Devices and methods for use in performing transmyocardial coronary bypass

Country Status (5)

Country Link
EP (1) EP1121067A1 (de)
JP (1) JP2002527141A (de)
AU (2) AU6506799A (de)
CA (1) CA2347457A1 (de)
WO (1) WO2000021463A1 (de)

Cited By (17)

* Cited by examiner, † Cited by third party
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US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US6302892B1 (en) 1999-08-04 2001-10-16 Percardia, Inc. Blood flow conduit delivery system and method of use
WO2002030330A3 (en) * 2000-10-11 2002-08-22 Heartstent Corp Autoanastomosis
WO2002030326A3 (en) * 2000-10-11 2002-09-06 Heartstent Corp Transmyocardial implant with anchor element
WO2006138010A2 (en) * 2005-06-17 2006-12-28 Percardia, Inc. Hinged tissue implant and related methods and devices for delivering such an implant
US7727268B2 (en) 2003-07-17 2010-06-01 Medtronic Vascular, Inc. Methods and devices for placing a fistula device in fluid communication with a target vessel
US8156942B2 (en) 2003-07-22 2012-04-17 Medtronic Vascular, Inc. Method of implanting a transmyocardial stent
US10695171B2 (en) 2010-11-05 2020-06-30 Cook Medical Technologies Llc Stent structures for use with valve replacements
US10993805B2 (en) 2008-02-26 2021-05-04 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US11185405B2 (en) 2013-08-30 2021-11-30 Jenavalve Technology, Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US11197754B2 (en) 2017-01-27 2021-12-14 Jenavalve Technology, Inc. Heart valve mimicry
US11337800B2 (en) 2015-05-01 2022-05-24 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US11357624B2 (en) 2007-04-13 2022-06-14 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US11517431B2 (en) 2005-01-20 2022-12-06 Jenavalve Technology, Inc. Catheter system for implantation of prosthetic heart valves
US11564794B2 (en) 2008-02-26 2023-01-31 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11589981B2 (en) 2010-05-25 2023-02-28 Jenavalve Technology, Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent

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Publication number Priority date Publication date Assignee Title
JP6167811B2 (ja) * 2013-09-30 2017-07-26 日本ゼオン株式会社 管腔臓器間バイパス用ステント

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Cited By (27)

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Publication number Priority date Publication date Assignee Title
US8597226B2 (en) 1998-09-10 2013-12-03 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US7704222B2 (en) 1998-09-10 2010-04-27 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US7736327B2 (en) 1998-09-10 2010-06-15 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US8216174B2 (en) 1998-09-10 2012-07-10 Jenavalve Technology, Inc. Methods and conduits for flowing blood from a heart chamber to a blood vessel
US6302892B1 (en) 1999-08-04 2001-10-16 Percardia, Inc. Blood flow conduit delivery system and method of use
WO2002030330A3 (en) * 2000-10-11 2002-08-22 Heartstent Corp Autoanastomosis
WO2002030326A3 (en) * 2000-10-11 2002-09-06 Heartstent Corp Transmyocardial implant with anchor element
US6582463B1 (en) 2000-10-11 2003-06-24 Heartstent Corporation Autoanastomosis
US7727268B2 (en) 2003-07-17 2010-06-01 Medtronic Vascular, Inc. Methods and devices for placing a fistula device in fluid communication with a target vessel
US8156942B2 (en) 2003-07-22 2012-04-17 Medtronic Vascular, Inc. Method of implanting a transmyocardial stent
US11517431B2 (en) 2005-01-20 2022-12-06 Jenavalve Technology, Inc. Catheter system for implantation of prosthetic heart valves
WO2006138010A3 (en) * 2005-06-17 2007-03-01 Percardia Inc Hinged tissue implant and related methods and devices for delivering such an implant
WO2006138010A2 (en) * 2005-06-17 2006-12-28 Percardia, Inc. Hinged tissue implant and related methods and devices for delivering such an implant
US11357624B2 (en) 2007-04-13 2022-06-14 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US10993805B2 (en) 2008-02-26 2021-05-04 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11154398B2 (en) 2008-02-26 2021-10-26 JenaValve Technology. Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11564794B2 (en) 2008-02-26 2023-01-31 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US11589981B2 (en) 2010-05-25 2023-02-28 Jenavalve Technology, Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
US11554011B2 (en) 2010-11-05 2023-01-17 Cook Medical Technologies Llc Stent structures for use with valve replacements
US10695171B2 (en) 2010-11-05 2020-06-30 Cook Medical Technologies Llc Stent structures for use with valve replacements
US11602428B2 (en) 2010-11-05 2023-03-14 Cook Medical Technologies Llc Stent structures for use with valve replacements
US11911270B2 (en) 2010-11-05 2024-02-27 Cook Medical Technologies Llc Stent structures for use with valve replacements
US11185405B2 (en) 2013-08-30 2021-11-30 Jenavalve Technology, Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US11337800B2 (en) 2015-05-01 2022-05-24 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
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US11197754B2 (en) 2017-01-27 2021-12-14 Jenavalve Technology, Inc. Heart valve mimicry

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JP2002527141A (ja) 2002-08-27
AU2003234967A1 (en) 2003-09-11
AU6506799A (en) 2000-05-01
CA2347457A1 (en) 2000-04-20
EP1121067A1 (de) 2001-08-08
WO2000021463A9 (en) 2000-09-21

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