WO2000016749A1 - Procede de preparation de nouvelles formulations galeniques du fenofibrate, formulations galeniques obtenues par ledit procede et leurs applications - Google Patents
Procede de preparation de nouvelles formulations galeniques du fenofibrate, formulations galeniques obtenues par ledit procede et leurs applications Download PDFInfo
- Publication number
- WO2000016749A1 WO2000016749A1 PCT/FR1999/002155 FR9902155W WO0016749A1 WO 2000016749 A1 WO2000016749 A1 WO 2000016749A1 FR 9902155 W FR9902155 W FR 9902155W WO 0016749 A1 WO0016749 A1 WO 0016749A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fenofibrate
- agents
- granulation
- liquid medium
- aggregate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR9913782-8A BR9913782A (pt) | 1998-09-17 | 1999-09-10 | Processo de preparação de uma formualação galênica que compreende fenofibrato como princìpio ativo, formulação galênica, medicamento e utilizações de um meio lìquido e de partìculas de fenofibrato |
AU55235/99A AU5523599A (en) | 1998-09-17 | 1999-09-10 | Method for preparing novel fenofibrate galenic formulations, galenic formulations obtained and applications |
JP2000573710A JP2002526438A (ja) | 1998-09-17 | 1999-09-10 | 新規なフェノフィブラートガレヌス製剤の調製方法、得られるガレヌス製剤、及び応用 |
SK355-2001A SK284950B6 (sk) | 1998-09-17 | 1999-09-10 | Spôsob prípravy galenických foriem fenofibrátu a ich použitie |
AT99941732T ATE230979T1 (de) | 1998-09-17 | 1999-09-10 | Verfahren zur herstellung neuer fenofibrathaltiger arzneiformulierungen, dadurch hergestellte arzneiformulierungen und ihre verwendung |
DE69904954T DE69904954D1 (de) | 1998-09-17 | 1999-09-10 | Verfahren zur herstellung neuer fenofibrathaltiger arzneiformulierungen, dadurch hergestellte arzneiformulierungen und ihre verwendung |
CA002342742A CA2342742A1 (fr) | 1998-09-17 | 1999-09-10 | Procede de preparation de nouvelles formulations galeniques du fenofibrate, formulations galeniques obtenues par ledit procede et leurs applications |
EP99941732A EP1112064B1 (fr) | 1998-09-17 | 1999-09-10 | Procede de preparation de nouvelles formulations galeniques du fenofibrate, formulations galeniques obtenues par ledit procede et leurs applications |
PL346714A PL194847B1 (pl) | 1998-09-17 | 1999-09-10 | Sposób wytwarzania nowych fenofibratowych preparatów galenowych, otrzymane preparaty galenowe i zastosowanie ciekłego medium |
MXPA01002801A MXPA01002801A (es) | 1998-09-17 | 1999-09-10 | Metodo para preparar nuevas formulaciones galenicas de fenofibra, formulaciones galenicas obtenidas y aplicaciones. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR98/11611 | 1998-09-17 | ||
FR9811611A FR2783421B1 (fr) | 1998-09-17 | 1998-09-17 | Procede de preparation de nouvelles formulations galeniques du fenofibrate, formulations galeniques obtenues par ledit procede et leurs applications |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000016749A1 true WO2000016749A1 (fr) | 2000-03-30 |
Family
ID=9530543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR1999/002155 WO2000016749A1 (fr) | 1998-09-17 | 1999-09-10 | Procede de preparation de nouvelles formulations galeniques du fenofibrate, formulations galeniques obtenues par ledit procede et leurs applications |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1112064B1 (fr) |
JP (1) | JP2002526438A (fr) |
KR (1) | KR100712032B1 (fr) |
AT (1) | ATE230979T1 (fr) |
AU (1) | AU5523599A (fr) |
BR (1) | BR9913782A (fr) |
CA (1) | CA2342742A1 (fr) |
CZ (1) | CZ298634B6 (fr) |
DE (1) | DE69904954D1 (fr) |
ES (1) | ES2190819T3 (fr) |
FR (1) | FR2783421B1 (fr) |
MX (1) | MXPA01002801A (fr) |
PL (1) | PL194847B1 (fr) |
SK (1) | SK284950B6 (fr) |
WO (1) | WO2000016749A1 (fr) |
ZA (1) | ZA200101894B (fr) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004028506A1 (fr) * | 2002-09-24 | 2004-04-08 | Ranbaxy Laboratories Limited | Compositions pharmaceutiques de fenofibrate par voie orale a biodisponibilite elevee |
US6982281B1 (en) | 2000-11-17 | 2006-01-03 | Lipocine Inc | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
US7927627B2 (en) | 2002-05-24 | 2011-04-19 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
US8663693B2 (en) | 2001-08-09 | 2014-03-04 | Jagotec Ag | Nanoparticulate formulations of fenofibrate |
US8865695B2 (en) | 2009-01-08 | 2014-10-21 | Lipocine Inc. | Steroidal compositions |
EP2842547A1 (fr) | 2013-08-27 | 2015-03-04 | Freund Pharmatec Ltd. | Compositions de fénofibrate améliorées |
US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
EP2878311A1 (fr) | 2013-11-27 | 2015-06-03 | Freund Pharmatec Ltd. | Amélioration de la solubilité de médicaments hydrophobes |
US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9498485B2 (en) | 2014-08-28 | 2016-11-22 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
US10561615B2 (en) | 2010-12-10 | 2020-02-18 | Lipocine Inc. | Testosterone undecanoate compositions |
US11559530B2 (en) | 2016-11-28 | 2023-01-24 | Lipocine Inc. | Oral testosterone undecanoate therapy |
US11707467B2 (en) | 2014-08-28 | 2023-07-25 | Lipocine Inc. | (17-ß)-3-oxoandrost-4-en-17YL tridecanoate compositions and methods of their preparation and use |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2795961B1 (fr) * | 1999-07-09 | 2004-05-28 | Ethypharm Lab Prod Ethiques | Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation |
FR2819720B1 (fr) | 2001-01-22 | 2004-03-12 | Fournier Lab Sa | Nouveaux comprimes de fenofibrate |
EP1923053A1 (fr) * | 2006-09-27 | 2008-05-21 | Novartis AG | Composition pharmaceutique comprenant de la nilotinib ou son sel |
CN104352466A (zh) * | 2014-11-17 | 2015-02-18 | 辰欣药业股份有限公司 | 一种非诺贝特组合物及其制剂 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0330532A1 (fr) * | 1988-02-26 | 1989-08-30 | Fournier Industrie Et Sante | Nouvelle forme galénique du fénofibrate |
FR2722984A1 (fr) * | 1994-07-26 | 1996-02-02 | Effik Laboratoires | Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees |
WO1996036318A2 (fr) * | 1995-05-19 | 1996-11-21 | Lek, Tovarna Farmacevtskih In Kemic^¿Nih Izdelkov,D.D. | Forme pharmaceutique a trois phases a liberation constante et lente d'un ingredient actif amorphe pour administration quotidienne unique |
EP0793958A2 (fr) * | 1996-03-06 | 1997-09-10 | Durachemie GmbH & Co. KG | Procédé de préparation d'un composition contenant du fénofibrate |
WO1998031361A1 (fr) * | 1997-01-17 | 1998-07-23 | Laboratoires Fournier S.A. | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
-
1998
- 1998-09-17 FR FR9811611A patent/FR2783421B1/fr not_active Expired - Fee Related
-
1999
- 1999-09-10 MX MXPA01002801A patent/MXPA01002801A/es unknown
- 1999-09-10 AT AT99941732T patent/ATE230979T1/de not_active IP Right Cessation
- 1999-09-10 ES ES99941732T patent/ES2190819T3/es not_active Expired - Lifetime
- 1999-09-10 DE DE69904954T patent/DE69904954D1/de not_active Expired - Lifetime
- 1999-09-10 SK SK355-2001A patent/SK284950B6/sk not_active IP Right Cessation
- 1999-09-10 JP JP2000573710A patent/JP2002526438A/ja active Pending
- 1999-09-10 BR BR9913782-8A patent/BR9913782A/pt not_active IP Right Cessation
- 1999-09-10 PL PL346714A patent/PL194847B1/pl not_active IP Right Cessation
- 1999-09-10 EP EP99941732A patent/EP1112064B1/fr not_active Revoked
- 1999-09-10 KR KR1020017003463A patent/KR100712032B1/ko not_active IP Right Cessation
- 1999-09-10 CA CA002342742A patent/CA2342742A1/fr not_active Abandoned
- 1999-09-10 WO PCT/FR1999/002155 patent/WO2000016749A1/fr active IP Right Grant
- 1999-09-10 CZ CZ20010979A patent/CZ298634B6/cs not_active IP Right Cessation
- 1999-09-10 AU AU55235/99A patent/AU5523599A/en not_active Abandoned
-
2001
- 2001-03-07 ZA ZA200101894A patent/ZA200101894B/en unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0330532A1 (fr) * | 1988-02-26 | 1989-08-30 | Fournier Industrie Et Sante | Nouvelle forme galénique du fénofibrate |
FR2722984A1 (fr) * | 1994-07-26 | 1996-02-02 | Effik Laboratoires | Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees |
WO1996036318A2 (fr) * | 1995-05-19 | 1996-11-21 | Lek, Tovarna Farmacevtskih In Kemic^¿Nih Izdelkov,D.D. | Forme pharmaceutique a trois phases a liberation constante et lente d'un ingredient actif amorphe pour administration quotidienne unique |
EP0793958A2 (fr) * | 1996-03-06 | 1997-09-10 | Durachemie GmbH & Co. KG | Procédé de préparation d'un composition contenant du fénofibrate |
WO1998031361A1 (fr) * | 1997-01-17 | 1998-07-23 | Laboratoires Fournier S.A. | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
Cited By (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6982281B1 (en) | 2000-11-17 | 2006-01-03 | Lipocine Inc | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
US8663693B2 (en) | 2001-08-09 | 2014-03-04 | Jagotec Ag | Nanoparticulate formulations of fenofibrate |
US7927627B2 (en) | 2002-05-24 | 2011-04-19 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
US7931917B2 (en) | 2002-05-24 | 2011-04-26 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
WO2004028506A1 (fr) * | 2002-09-24 | 2004-04-08 | Ranbaxy Laboratories Limited | Compositions pharmaceutiques de fenofibrate par voie orale a biodisponibilite elevee |
US8865695B2 (en) | 2009-01-08 | 2014-10-21 | Lipocine Inc. | Steroidal compositions |
US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
US11052096B2 (en) | 2009-01-08 | 2021-07-06 | Lipocine Inc. | Steroidal compositions |
US10799513B2 (en) | 2010-11-30 | 2020-10-13 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9757390B2 (en) | 2010-11-30 | 2017-09-12 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9205057B2 (en) | 2010-11-30 | 2015-12-08 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9480690B2 (en) | 2010-11-30 | 2016-11-01 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US10973833B2 (en) | 2010-11-30 | 2021-04-13 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US10716794B2 (en) | 2010-11-30 | 2020-07-21 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9943527B2 (en) | 2010-11-30 | 2018-04-17 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9949985B2 (en) | 2010-11-30 | 2018-04-24 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US10226473B2 (en) | 2010-11-30 | 2019-03-12 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US10561615B2 (en) | 2010-12-10 | 2020-02-18 | Lipocine Inc. | Testosterone undecanoate compositions |
EP2842547A1 (fr) | 2013-08-27 | 2015-03-04 | Freund Pharmatec Ltd. | Compositions de fénofibrate améliorées |
WO2015078936A1 (fr) | 2013-11-27 | 2015-06-04 | Freund Pharmatec Ltd. | Amélioration de la solubilité pour des médicaments hydrophobes |
EP2878311A1 (fr) | 2013-11-27 | 2015-06-03 | Freund Pharmatec Ltd. | Amélioration de la solubilité de médicaments hydrophobes |
US9757389B2 (en) | 2014-08-28 | 2017-09-12 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
US11298365B2 (en) | 2014-08-28 | 2022-04-12 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
US9498485B2 (en) | 2014-08-28 | 2016-11-22 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
US11707467B2 (en) | 2014-08-28 | 2023-07-25 | Lipocine Inc. | (17-ß)-3-oxoandrost-4-en-17YL tridecanoate compositions and methods of their preparation and use |
US11872235B1 (en) | 2014-08-28 | 2024-01-16 | Lipocine Inc. | Bioavailable solid state (17-β)-Hydroxy-4-Androsten-3-one esters |
US11559530B2 (en) | 2016-11-28 | 2023-01-24 | Lipocine Inc. | Oral testosterone undecanoate therapy |
Also Published As
Publication number | Publication date |
---|---|
MXPA01002801A (es) | 2002-04-08 |
BR9913782A (pt) | 2001-06-05 |
ATE230979T1 (de) | 2003-02-15 |
JP2002526438A (ja) | 2002-08-20 |
SK3552001A3 (en) | 2001-09-11 |
PL346714A1 (en) | 2002-02-25 |
DE69904954D1 (de) | 2003-02-20 |
PL194847B1 (pl) | 2007-07-31 |
EP1112064B1 (fr) | 2003-01-15 |
ZA200101894B (en) | 2003-01-07 |
CA2342742A1 (fr) | 2000-03-30 |
FR2783421A1 (fr) | 2000-03-24 |
KR20010075182A (ko) | 2001-08-09 |
FR2783421B1 (fr) | 2000-11-24 |
EP1112064A1 (fr) | 2001-07-04 |
KR100712032B1 (ko) | 2007-04-27 |
SK284950B6 (sk) | 2006-03-02 |
CZ2001979A3 (cs) | 2001-08-15 |
AU5523599A (en) | 2000-04-10 |
ES2190819T3 (es) | 2003-08-16 |
CZ298634B6 (cs) | 2007-11-28 |
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