WO1999062577A1 - Recipient pre-rempli - Google Patents
Recipient pre-rempli Download PDFInfo
- Publication number
- WO1999062577A1 WO1999062577A1 PCT/AU1999/000422 AU9900422W WO9962577A1 WO 1999062577 A1 WO1999062577 A1 WO 1999062577A1 AU 9900422 W AU9900422 W AU 9900422W WO 9962577 A1 WO9962577 A1 WO 9962577A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- needle
- closure
- syringe
- plastic
- filled
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
- A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
Definitions
- This invention concerns pre-filled containers, cartridges and syringes. It relates most particularly to a new form of syringe which can be pre-filled, fitted with a hypodermic needle and packaged as a ready to use product.
- a stem which protrudes from the end of the syringe is susceptible to accidental knocks - both in production and in use and this can lead to contamination or inadvertent opening of the unit.
- a hypodermic needle in a system such as that described in PCT/AU/00723 it is necessary to remove the stem from the needle fitting before a hypodermic needle can be attached. This means that the needle must be fitted in a separate step immediately prior to use. This can be inconvenient and there exists the possibility of contamination during the needle attachment operation.
- a pre-filled plastic syringe which includes:
- the needle fitting includes a hollow truncated cone, the interior of which is in liquid communication with the interior of the barrel.
- the needle fitting is in the form of a truncated cone surrounded by a peripheral wall spaced from the cone.
- An example of such a fitting is the "luer lock" needle fitting.
- a luer lock fitting incorporates a screw thread on the internal surface of the peripheral wall so to facilitate screw threaded engagement of a hypodermic needle onto the needle fitting.
- Hypodermic needles used in conjunction with luer lock needle fittings are attached at one end to a support which is conical, hollow and dimensioned to fit over and onto the central cone of the luer lock fitting.
- the base of the needle support includes a flange which is shaped to engage with the screw thread on the internal surface of the peripheral wall so that twisting of the hypodermic needle relative to the needle fitting facilitates engagement.
- the syringe of this invention utilise a luer lock needle fitting and that the syringe be used in conjunction with a hypodermic needle attached to a conical support as described above.
- the closure may be a separate component located within the barrel or needle fitting such as by a friction fit or other suitable means. In such case it is preferred that the closure be made of such material and be of such thickness that it may be punctured readily.
- the closure is preferably a wall portion which is frangibly connected to the inner surface of the barrel or to the inner surface of the needle fitting and which extends across the opening in the barrel or needle fitting. Most preferably the closure is located wholly within the needle fitting of the syringe. In the embodiment of the invention where the needle fitting includes a hollow truncated cone in liquid communication with the interior of the barrel it is preferred that the closure be an integral wall portion which is connected to the inner surface of the cone and extends across its opening. In this embodiment of the invention the wall portion can be located at any position along the inner wall of the needle fitting.
- the truncated cone is frangibly attached to the inner surface of the truncated cone and located at least 2.0 mm and most preferably at least 4.0 mm from the open end of the truncated cone so to reduce the prospect of the wall portion being broken away from the inner wall and (thus breaking the seal created by the wall portion) inadvertantly.
- the closure either be puncturable by the rear needle of a standard double sided hypodermic needle (in which case the closure is positioned close to the open end of the needle fitting) or alternatively that it be frangible so that it may be detached or in part broken away from the inner surface of the truncated cone or the barrel by utilizing a suitable tool.
- the syringe includes a truncated conical needle fitting and the closure is a wall portion which extends across the internal passage of the cone and is frangibly attached to the inner surface of the cone.
- the wall portion include a circumferential weakened section at or adjacent to its connection to the inner surface of the cone.
- the weakened section thus creates a "tear line" along which the closure may be detached (at least in part) from the inner surface of the cone.
- the wall portion is between 0.8 mm to 1.5 mm in thickness except in the weakened section where it is preferably between 0.05 to 0.2 mm in thickness. Whilst it is possible to utilize a weakened section which extends all the way around the wall portion this is not preferred as the application of a force against the wall portion in such an embodiment might result in the complete separation of the closure from the needle fitting.
- the weakened section extend circumferentially through about 330 - 350° so that when the closure is broken away from the inner surface of the cone along the weakened section the closure will still remain attached to the inside of the needle fitting and will be able to hinge about that section at or adjacent to the inner surface of the cone which is not weakened.
- the seal provided by the wall portion may be broken by applying a force against the wall portion.
- a tool which incorporates a push rod of smaller diameter from the internal diameter of the cone and which is of sufficient length to reach the wall portion may be utilized for this purpose.
- a tool has a flat end face sized to contact most of the surface area of the closure.
- the pre-filled syringe of the invention also includes a hollow closure opening conduit, a hypodermic needle and a needle support having an internal cavity, said hypodermic needle being attached at one end to the needle support and said needle support being positioned over (but not fully engaged with) the needle fitting, wherein a first end of said closure opening conduit is positioned within said internal cavity and a second end of the closure opening conduit is positioned within said needle fitting, the closure opening conduit being in liquid communication with the hypodermic needle and being of such length that movement of the needle support towards the moveable stopper end of the syringe will cause the closure opening conduit to break the seal provided by the closure.
- the length of the closure opening conduit is such that full engagement of the needle support on the needle fitting provides sufficient movement of the needle support (and hence the closure opening conduit) to break the seal provided by the closure.
- the cavity in the needle support includes an end face in which there is a centrally disposed aperture.
- the hypodermic needle may be fitted and secured at one end within the aperture so that it extends away from the cavity.
- the closure opening conduit is preferably located within the cavity with the first end abutting the end face of the housing with the internal passage therein in alignment with the aperture in the end face of the needle support.
- the other end of the closure opening conduit is preferably adjacent to or abuts the surface of the closure. In this way, movement of the needle support towards the moveable stopper end of the syringe will cause the end face to press against the first end of the closure opening conduit and in turn apply pressure to the closure.
- closure opening conduit By moving the support fully onto the needle fitting the closure opening conduit will be moved sufficiently to break the frangible connection of the closure to the needle fitting and thus facilitate direct liquid communication from the barrel of the syringe to the hypodermic needle past the opened closure and through the closure opening conduit.
- the closure opening conduit may be integral with and extend from the needle support but it is preferably a separate component.
- the closure opening conduit includes a central conduit and fins or ribs which extend outwardly therefrom so to minimize the contact between the closure opening conduit and the inner surface of the needle fitting. This reduces friction between the surfaces.
- other closure opening means may be utilised which does not incorporate a conduit but is simply shaped to allow liquid passage.
- the closure opening means might be a solid rod which is of smaller diameter than the smallest diameter of the passage in the needle fitting with guide ribs which are configured to contact the inner surface of the needle fitting.
- the pre-filled syringe also includes an overcap placed over the hypodermic needle.
- a tamper evident band may be provided around the base of the overcap so that prior removal of the overcap can be recognised by absence of the band or by its fracture.
- the embodiment of the invention utilizing a closure opening conduit provides significant advantages in ease of use and avoidance of contamination.
- the filled and assembled syringe may also be hermetically sealed within a clear plastic wrap such as cellophane prior to delivering the product out of the clean environment.
- the pre-filled product may be delivered to practitioners with the hypodermic needle in position over the needle fitting but not fully engaged.
- the hypodermic needle may be pushed or twisted onto the needle fitting whilst the product is still in the hermitically sealed package.
- the complete seating of the hypodermic needle onto the needle fitting causes the seal formed by the closure to be broken so that when the package is opened removal of the hypodermic needle overcap (if present) provides an opened pre-filled syringe ready for use and not susceptible to contamination by the application of additional parts or products to the syringe after the package has been opened.
- the pre-filled plastic syringe of the invention is preferably manufactured from a thermoplastics material such as polypropylene.
- suitable materials include translucent and transparent plastics such as PET, polyamides or TPX. Other suitable materials are well known to those skilled in the art.
- FIG. 1 is a schematic diagram illustrating a pre-filled syringe packaged within an outer wrapper
- Figure 2 is a schematic diagram illustrating the pre-filled syringe shown in
- Figure 3 is an end view of the pre-filled syringe shown in Figure 2 viewed from the plunger end;
- Figure 4 is an enlarged schematic view of the needle fitting and closure of the pre-filled syringe shown in Figure 2;
- Figure 5 is an enlarged view of the central cone of the needle fitting shown in Figure 4 and the associated closure;
- Figure 6 is a schematic diagram illustrating the needle fitting end of the pre-filled syringe shown in Figure 2 with the hypodermic needle and needle support positioned over the end of the needle fitting of the syringe but prior to full engagement;
- Figure 7 is a schematic diagram illustrating the needle fitting and hypodermic needle assembly as shown in Figure 6, after the hypodermic needle and needle support have been positioned firmly onto the needle fitting of the syringe;
- Figure 8 is a schematic diagram illustrating the needle fitting end of the pre-filled syringe and the passage through which the injectable liquid can flow once the closure has been opened;
- Figure 9 is a schematic representation of the closure opening conduit
- Figure 10 is a cross sectional view of a removable band intended for use in holding an overcap in position over the hypodermic needle prior to use;
- Figure 11 is a schematic diagram illustrating an alternative embodiment of the invention utilising a double sided hypodermic needle
- Figure 12 is a schematic representation of the needle fitting end of the pre- filled syringe illustrated in Figure 11;
- Figure 13 is a schematic diagram of the end of the truncated cone in the needle fitting illustrated in Figure 12;
- Figure 14 is a schematic representation of the double sided hypodermic needle with support and overcap.
- Figure 1 is a schematic representation which illustrates how a preferred embodiment of the invention might be presented for distribution to doctors and other medical practitioners.
- the pre-filled syringe 1 is preferably manufactured by injection moulding all of the components in an aseptic environment, assembling and filling the syringe in the aseptic environment and sealing it within an outer wrapper 17.
- the syringe 1 which is illustrated without the protective packaging in Figure 2, includes a barrel 1a and a plunger rod 2 affixed to a moveable stopper 3.
- Moveable stopper 3 seals the barrel at one end - the other end of the barrel being sealed by a closure 9 which is integral with a central truncated cone 13a of the needle fitting 13 at the other end of the syringe.
- the barrel 1a is filled with an injectable liquid 10 and this liquid is housed within the barrel 1a between moveable stopper 3 and closure 9.
- Needle support 7 includes an internal cavity 7a (best seen in Figure 6) and is positioned over the end of truncated cone 13a of the needle fitting 13.
- Hypodermic needle 5 is hollow and is in liquid communication with cavity 7a.
- a hollow closure opening conduit in the nature of a separate tube 21 (again seen better in Figure 6) is positioned between needle support 7 and closure 9 and the use of this tube in conjunction with needle support 7 in detaching closure 9 is described below.
- Hypodermic needle 5 is protected by an overcap 6 which is held in position by a circumferential band 4 which is shown in full detail in Figure 10.
- the needle fitting 13 also includes an outer peripheral wall 15.
- Figure 3 illustrates the syringe from the plunger rod end of the syringe, showing thumb press 12, finger support flanges 16 and gripping ribs 18.
- FIG 4 illustrates the needle fitting end of the pre-filled syringe shown in Figure 2.
- the needle fitting includes a central truncated cone 13a and a peripheral outer wall 15. This is in the nature of a standard "luer lock” type needle fitting and is thus suitable for use in conjunction with a standard hypodermic and needle support of the type as shown in Figure 2.
- the peripheral wall 15 includes a spiral rib 20 which facilitates screw threaded engagement of needle support 7 onto the needle fitting 13.
- the needle fitting 13 has an opening 22 between peripheral wall 15 and central truncated cone 13a.
- a closure 9 in the form of an integral end wall portion located within the central truncated cone 13a.
- closure 9 whilst being integral with the inner surface of central truncated cone 13a is frangibly connected thereto as is better shown in Figure 5.
- closure 9 Adjacent to the inner surface of truncated cone 13a closure 9 includes a tear line
- the syringe is made from polypropylene and closure 9 is about 1.2 mm in thickness.
- the tear line is about 0.1 mm in thickness.
- tear line 8 does not extend around the full circumference of closure 9 so that when a force is applied against the closure, at least some part of the closure will remain attached to the inner surface of truncated cone 13a so to leave the closure 9 attached to a portion of the inner surface of truncated cone 13a.
- the diameter of the inner passage of central truncated cone 13a is slightly larger on the barrel side of the closure 9 so to accommodate the closure when it is detached and folded back by tube 21.
- FIG. 6 The operation of the syringe is shown in more detail in Figures 6, 7 and 8.
- the needle fitting end of the syringe is shown with closure 9 sealing the syringe.
- Needle support 7 is positioned over the central truncated cone 13a but the flange 7b of needle support 7 has not been engaged with the screw thread portion 20 of the peripheral wall 15.
- Tube 21 is located with a first end in abutment against the end of cavity 7a and with the other end in abutment against the face of closure 9.
- Tube 21 has a central passage 21a which is aligned so that it is in direct fluid communication with the passage 5a in hypodermic needle 5. Tamper indicating band 4 holds overcap 6 in position.
- Figure 7 shows the needle fitting end of the pre-filled syringe after part of closure 9 has been detached from the inner surface of central truncated cone 13a.
- this is achieved by applying a force to overcap 6 or circumferential band 4 in the direction of the moveable stopper end of the pre- filled syringe.
- This force will in turn move the needle support 7 further onto truncated cone 13a.
- the force be used in conjunction with a twisting action so to screw the needle support 7 onto central cone 13a and towards the moveable stopper end of the syringe.
- This movement of support 7 causes a force to be applied to tube 21 which in turn applies a force to closure 9 causing it to tear away from the inner surface of central truncated cone 13a along tear line 8.
- the tear line 8 does not extend about the full circumference of the closure and thus it hinges to one side as can be clearly seen in Figure 7.
- tube 21 is chamfered at the end. This facilitates easy insertion of tube 21 into the truncated cone 13a when the product is being assembled but it also means that the tube 21 is less likely to completely detach the closure 9 from the inner surface of truncated cone 13a.
- the opened closure 9 is held between the inner surface of truncated cone 13a and the outer surface of tube 21 once needle support 7 has been firmly engaged on needle fitting 13.
- FIG 8 the needle fitting end of pre-filled syringe 1 is shown ready for use. Tamper evident band 4 has been removed together with overcap 6 (contrast with Figure 7).
- the injectable liquid 10 can now be expressed out of syringe 1 in the direction of the arrow shown in Figure 8 by moving plunger rod 2 towards the needle fitting end of the syringe. The liquid 10 will move in the direction of the arrow in Figure 8 through the passage 21a and thereafter through the hollow hypodermic needle 5.
- Figure 9 is a schematic representation showing tube 21 and Figure 10 is an enlarged cross section of tamper evident band 4.
- This band includes an internal rib 14 and an end flange 14a adapted to clip around the flange 6a of overcap 6.
- An alternative embodiment of the invention is shown in Figures 11 to 14.
- FIG. 11 there is shown a pre-filled syringe 1 which has a barrel 1a, a plunger rod 2 and a moveable stopper 3.
- Needle fitting 13 includes a central truncated cone 13a and a peripheral wall 15.
- the hypodermic needle 5 is fitted to a needle support 7.
- the hypodermic needle 5 extends through the needle support 7 and has a sharpened end 5b located within cavity 7a.
- the sharpened end 5b of the hypodermic needle 5 is located close to but not in contact with closure 9.
- closure 9 be located close to the end of central cone 13a. Whilst it may be located at the very end of central cone 13a, it is preferred that it be located a short distance within the cone, e.g. 0.5 mm from the end of cone 13a.
- Figure 14 is an enlarged representation of hypodermic needle 5, needle support 7 and overcap 6.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0102251A HUP0102251A3 (en) | 1998-06-03 | 1999-05-31 | Pre-filled container |
JP2000551830A JP2002516724A (ja) | 1998-06-03 | 1999-05-31 | 充填済容器 |
AU40247/99A AU751878B2 (en) | 1998-06-03 | 1999-05-31 | Pre-filled container |
KR1020007013640A KR20010071378A (ko) | 1998-06-03 | 1999-05-31 | 프리-필드 컨테이너 |
EP99923321A EP1082152A4 (fr) | 1998-06-03 | 1999-05-31 | Recipient pre-rempli |
IL14001599A IL140015A0 (en) | 1998-06-03 | 1999-05-31 | Pre-filled container |
SK1792-2000A SK17922000A3 (sk) | 1998-06-03 | 1999-05-31 | Predplnená nádržka |
CA002334104A CA2334104A1 (fr) | 1998-06-03 | 1999-05-31 | Recipient pre-rempli |
PL99345206A PL345206A1 (en) | 1998-06-03 | 1999-05-31 | Pre-filled container |
BR9910865-8A BR9910865A (pt) | 1998-06-03 | 1999-05-31 | Recipiente pré enchido |
EEP200000712A EE200000712A (et) | 1998-06-03 | 1999-05-31 | Eeltäidetud süstal ja selle kasutamine |
NZ508524A NZ508524A (en) | 1998-06-03 | 1999-05-31 | Pre-filled syringe with an integral needle and a closure at the needle fitting end |
IS5745A IS5745A (is) | 1998-06-03 | 2000-11-29 | Áfyllt ílát |
NO20006136A NO20006136L (no) | 1998-06-03 | 2000-12-01 | Forhåndsfylt beholder |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPP3878A AUPP387898A0 (en) | 1998-06-03 | 1998-06-03 | Pre-filled container |
AUPP3878 | 1998-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999062577A1 true WO1999062577A1 (fr) | 1999-12-09 |
Family
ID=3808123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AU1999/000422 WO1999062577A1 (fr) | 1998-06-03 | 1999-05-31 | Recipient pre-rempli |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1082152A4 (fr) |
JP (1) | JP2002516724A (fr) |
KR (1) | KR20010071378A (fr) |
CN (1) | CN1303307A (fr) |
AR (1) | AR018445A1 (fr) |
AU (2) | AUPP387898A0 (fr) |
BR (1) | BR9910865A (fr) |
CA (1) | CA2334104A1 (fr) |
EE (1) | EE200000712A (fr) |
EG (1) | EG21423A (fr) |
GC (1) | GC0000057A (fr) |
HU (1) | HUP0102251A3 (fr) |
ID (1) | ID28383A (fr) |
IL (1) | IL140015A0 (fr) |
IS (1) | IS5745A (fr) |
NO (1) | NO20006136L (fr) |
NZ (1) | NZ508524A (fr) |
PL (1) | PL345206A1 (fr) |
RU (1) | RU2217174C2 (fr) |
SK (1) | SK17922000A3 (fr) |
TR (1) | TR200003555T2 (fr) |
TW (1) | TW515293U (fr) |
WO (1) | WO1999062577A1 (fr) |
ZA (1) | ZA200006952B (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009061315A1 (fr) * | 2007-11-06 | 2009-05-14 | Hospira, Inc. | Dispositif d'injection et procédé de montage et d'activation |
US8657793B2 (en) | 2011-09-30 | 2014-02-25 | Becton Dickinson France, S.A.S | Space saving plunger cap and rod assembly |
US8672883B2 (en) | 2011-07-11 | 2014-03-18 | C. Garyen Denning | Fluid delivery device and methods |
EP3042689A1 (fr) * | 2013-09-02 | 2016-07-13 | Taisei Kako Co., Ltd. | Seringue et ensemble de seringue |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5798872B2 (ja) * | 2011-10-03 | 2015-10-21 | 大成化工株式会社 | キャップ、キャップ付きバレル、及びプレフィルドシリンジ |
CN111051420B (zh) | 2017-09-21 | 2023-02-10 | 株式会社Tbm | 热塑性树脂组合物以及用该热塑性树脂组合物形成的成型品 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4445895A (en) * | 1981-07-16 | 1984-05-01 | Sterling Drug Inc. | Prepackaged, disposable hypodermic syringes |
WO1992012746A1 (fr) | 1991-01-15 | 1992-08-06 | Astra Pharmaceuticals Pty. Ltd. | Seringue en plastique |
WO1996014100A1 (fr) | 1994-11-03 | 1996-05-17 | Astra Pharmaceuticals Pty. Ltd. | Seringue en matiere plastique avec capuchon |
GB2307643A (en) * | 1995-12-02 | 1997-06-04 | Epsom Glass Ind Ltd | Pre-fillable disposable syringe |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830193A (en) * | 1993-12-28 | 1998-11-03 | Higashikawa; Tetsuro | Syringe |
PT902694E (pt) * | 1995-08-22 | 2003-09-30 | Mdc Invest Holdings Inc | Ampolas de injeccao pre-cheias dotadas de agulha retractil |
-
1998
- 1998-06-03 AU AUPP3878A patent/AUPP387898A0/en not_active Abandoned
-
1999
- 1999-05-30 EG EG63099A patent/EG21423A/xx active
- 1999-05-31 NZ NZ508524A patent/NZ508524A/en unknown
- 1999-05-31 KR KR1020007013640A patent/KR20010071378A/ko not_active Application Discontinuation
- 1999-05-31 EP EP99923321A patent/EP1082152A4/fr not_active Withdrawn
- 1999-05-31 TR TR2000/03555T patent/TR200003555T2/xx unknown
- 1999-05-31 WO PCT/AU1999/000422 patent/WO1999062577A1/fr not_active Application Discontinuation
- 1999-05-31 CN CN99806889A patent/CN1303307A/zh active Pending
- 1999-05-31 BR BR9910865-8A patent/BR9910865A/pt not_active IP Right Cessation
- 1999-05-31 ID IDW20002510A patent/ID28383A/id unknown
- 1999-05-31 EE EEP200000712A patent/EE200000712A/xx unknown
- 1999-05-31 PL PL99345206A patent/PL345206A1/xx unknown
- 1999-05-31 SK SK1792-2000A patent/SK17922000A3/sk unknown
- 1999-05-31 RU RU2000130214/14A patent/RU2217174C2/ru not_active IP Right Cessation
- 1999-05-31 HU HU0102251A patent/HUP0102251A3/hu unknown
- 1999-05-31 IL IL14001599A patent/IL140015A0/xx unknown
- 1999-05-31 AU AU40247/99A patent/AU751878B2/en not_active Ceased
- 1999-05-31 JP JP2000551830A patent/JP2002516724A/ja active Pending
- 1999-05-31 CA CA002334104A patent/CA2334104A1/fr not_active Abandoned
- 1999-06-02 GC GCP1999166 patent/GC0000057A/xx active
- 1999-06-02 TW TW090223682U patent/TW515293U/zh not_active IP Right Cessation
- 1999-06-03 AR ARP990102637A patent/AR018445A1/es active IP Right Grant
-
2000
- 2000-11-27 ZA ZA200006952A patent/ZA200006952B/xx unknown
- 2000-11-29 IS IS5745A patent/IS5745A/is unknown
- 2000-12-01 NO NO20006136A patent/NO20006136L/no not_active Application Discontinuation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US4445895A (en) * | 1981-07-16 | 1984-05-01 | Sterling Drug Inc. | Prepackaged, disposable hypodermic syringes |
WO1992012746A1 (fr) | 1991-01-15 | 1992-08-06 | Astra Pharmaceuticals Pty. Ltd. | Seringue en plastique |
WO1996014100A1 (fr) | 1994-11-03 | 1996-05-17 | Astra Pharmaceuticals Pty. Ltd. | Seringue en matiere plastique avec capuchon |
GB2307643A (en) * | 1995-12-02 | 1997-06-04 | Epsom Glass Ind Ltd | Pre-fillable disposable syringe |
Non-Patent Citations (1)
Title |
---|
See also references of EP1082152A4 |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009061315A1 (fr) * | 2007-11-06 | 2009-05-14 | Hospira, Inc. | Dispositif d'injection et procédé de montage et d'activation |
AU2007361280B2 (en) * | 2007-11-06 | 2012-12-13 | Hospira, Inc. | Injection device and method of assembly and activation |
US8672883B2 (en) | 2011-07-11 | 2014-03-18 | C. Garyen Denning | Fluid delivery device and methods |
US8657793B2 (en) | 2011-09-30 | 2014-02-25 | Becton Dickinson France, S.A.S | Space saving plunger cap and rod assembly |
EP3042689A1 (fr) * | 2013-09-02 | 2016-07-13 | Taisei Kako Co., Ltd. | Seringue et ensemble de seringue |
EP3042689A4 (fr) * | 2013-09-02 | 2017-05-10 | Taisei Kako Co., Ltd. | Seringue et ensemble de seringue |
AU2014312881B2 (en) * | 2013-09-02 | 2019-05-09 | 3-D Matrix, Ltd. | Syringe and syringe set |
US10286200B2 (en) | 2013-09-02 | 2019-05-14 | Taisei Kako Co., Ltd. | Syringe and syringe set |
Also Published As
Publication number | Publication date |
---|---|
SK17922000A3 (sk) | 2001-10-08 |
ID28383A (id) | 2001-05-17 |
EE200000712A (et) | 2002-04-15 |
JP2002516724A (ja) | 2002-06-11 |
AU4024799A (en) | 1999-12-20 |
KR20010071378A (ko) | 2001-07-28 |
CN1303307A (zh) | 2001-07-11 |
PL345206A1 (en) | 2001-12-03 |
NO20006136D0 (no) | 2000-12-01 |
EP1082152A1 (fr) | 2001-03-14 |
GC0000057A (en) | 2004-06-30 |
IS5745A (is) | 2000-11-29 |
NO20006136L (no) | 2001-02-02 |
AR018445A1 (es) | 2001-11-14 |
AU751878B2 (en) | 2002-08-29 |
EG21423A (en) | 2001-10-31 |
IL140015A0 (en) | 2002-02-10 |
TW515293U (en) | 2002-12-21 |
HUP0102251A2 (hu) | 2001-10-28 |
BR9910865A (pt) | 2001-03-06 |
TR200003555T2 (tr) | 2001-06-21 |
ZA200006952B (en) | 2001-05-25 |
CA2334104A1 (fr) | 1999-12-09 |
NZ508524A (en) | 2002-06-28 |
EP1082152A4 (fr) | 2002-02-06 |
RU2217174C2 (ru) | 2003-11-27 |
HUP0102251A3 (en) | 2001-12-28 |
AUPP387898A0 (en) | 1998-06-25 |
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