WO1999055876A3 - Polypeptid mit immunogenen eigenschaften und veränderten biologischen funktionen eines proteins - Google Patents
Polypeptid mit immunogenen eigenschaften und veränderten biologischen funktionen eines proteins Download PDFInfo
- Publication number
- WO1999055876A3 WO1999055876A3 PCT/DE1999/001331 DE9901331W WO9955876A3 WO 1999055876 A3 WO1999055876 A3 WO 1999055876A3 DE 9901331 W DE9901331 W DE 9901331W WO 9955876 A3 WO9955876 A3 WO 9955876A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- protein
- biological functions
- immunogenic properties
- modified biological
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 230000008827 biological function Effects 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU48954/99A AU4895499A (en) | 1998-04-30 | 1999-04-30 | Polypeptide with immunogenic properties and with a protein with modified biological functions |
JP2000546020A JP2002512801A (ja) | 1998-04-30 | 1999-04-30 | 免疫原性特性および改変された生物学的タンパク質機能を有するポリペプチド |
EP99932615A EP1073751A2 (de) | 1998-04-30 | 1999-04-30 | Polypeptid mit immunogenen eigenschaften und veränderten biologischen funktionen eines proteins |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19819476.5 | 1998-04-30 | ||
DE19819476A DE19819476C1 (de) | 1998-04-30 | 1998-04-30 | Polypeptid mit immunogenen Eigenschaften und veränderten biologischen Funktionen eines Proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999055876A2 WO1999055876A2 (de) | 1999-11-04 |
WO1999055876A3 true WO1999055876A3 (de) | 2000-03-23 |
Family
ID=7866375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE1999/001331 WO1999055876A2 (de) | 1998-04-30 | 1999-04-30 | Polypeptid mit immunogenen eigenschaften und veränderten biologischen funktionen eines proteins |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1073751A2 (de) |
JP (1) | JP2002512801A (de) |
AU (1) | AU4895499A (de) |
DE (1) | DE19819476C1 (de) |
WO (1) | WO1999055876A2 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60126737T2 (de) | 2001-03-23 | 2007-11-08 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Modifizierte HPV E6- und E7-Gene und -Proteine als Impfstoff |
GB0120938D0 (en) * | 2001-08-29 | 2001-10-17 | Norchip As | Detection of human papillomavirus E7 mRNA |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0386734A2 (de) * | 1989-03-10 | 1990-09-12 | BEHRINGWERKE Aktiengesellschaft | Immunogene Regionen auf dem E-7-Protein des Humanen Papillomvirus Typ 16 |
WO1992010513A1 (en) * | 1990-12-12 | 1992-06-25 | The University Of Queensland | Subunit papillomavirus vaccine and peptides for use therein |
WO1992016636A1 (en) * | 1991-03-14 | 1992-10-01 | Cantab Pharmaceuticals Research Limited | Recombinant virus vectors encoding human papillomavirus proteins |
WO1993020844A1 (en) * | 1992-04-08 | 1993-10-28 | Cancer Research Campaign Technology Ltd. | Papillomavirus e7 protein |
WO1996019496A1 (en) * | 1994-12-20 | 1996-06-27 | Csl Limited | Variants of human papilloma virus antigens |
WO1998005790A1 (de) * | 1996-08-02 | 1998-02-12 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Vektor zur aktivierung des immunsystems gegen mit papillomviren bzw. sequenzen davon assoziierten zellen |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5180806A (en) * | 1988-05-16 | 1993-01-19 | The Scripps Research Institute | Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods |
-
1998
- 1998-04-30 DE DE19819476A patent/DE19819476C1/de not_active Expired - Fee Related
-
1999
- 1999-04-30 EP EP99932615A patent/EP1073751A2/de not_active Withdrawn
- 1999-04-30 WO PCT/DE1999/001331 patent/WO1999055876A2/de not_active Application Discontinuation
- 1999-04-30 AU AU48954/99A patent/AU4895499A/en not_active Abandoned
- 1999-04-30 JP JP2000546020A patent/JP2002512801A/ja active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0386734A2 (de) * | 1989-03-10 | 1990-09-12 | BEHRINGWERKE Aktiengesellschaft | Immunogene Regionen auf dem E-7-Protein des Humanen Papillomvirus Typ 16 |
WO1992010513A1 (en) * | 1990-12-12 | 1992-06-25 | The University Of Queensland | Subunit papillomavirus vaccine and peptides for use therein |
WO1992016636A1 (en) * | 1991-03-14 | 1992-10-01 | Cantab Pharmaceuticals Research Limited | Recombinant virus vectors encoding human papillomavirus proteins |
WO1993020844A1 (en) * | 1992-04-08 | 1993-10-28 | Cancer Research Campaign Technology Ltd. | Papillomavirus e7 protein |
WO1996019496A1 (en) * | 1994-12-20 | 1996-06-27 | Csl Limited | Variants of human papilloma virus antigens |
WO1998005790A1 (de) * | 1996-08-02 | 1998-02-12 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Vektor zur aktivierung des immunsystems gegen mit papillomviren bzw. sequenzen davon assoziierten zellen |
Non-Patent Citations (5)
Title |
---|
BALDWIN A.N. ET AL.: "Studies on the structure and binding properties of the cysteine-rich domains of rat low affinity Nerve Growth Factor Receptor (p75 NGFR)", J. BIOL. CHEM., vol. 267, no. 12, 25 April 1992 (1992-04-25), pages 8352 - 8359, XP002125301 * |
GREENSTONE H.L. ET AL.: "Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model", PROC. NATL. ACAD. SCI. USA, vol. 95, February 1998 (1998-02-01), pages 1800 - 1805, XP002125303 * |
JOCHMUS I. ET AL.: "Specificity of human cytotoxic T lymphocytes induced by a human papillomavirus type 16 E7-derived peptide", J. GEN. VIROL., vol. 78, 1997, pages 1689 - 1695, XP002125304 * |
MUELLER M ET AL: "IDENTIFICATION OF SEROREACTIVE REGIONS OF THE HUMAN PAPILLOMAVIRUS TYPE 16 PROTEINS E4, E6, E7 AND L1", JOURNAL OF GENERAL VIROLOGY,GB,SOCIETY FOR GENERAL MICROBIOLOGY, READING, vol. 71, pages 2709-2717, XP000318453, ISSN: 0022-1317 * |
THAIN A. ET AL.: "DNA binding and bending by the human papillomavirus type 16 E2 protein", J. BIOL. CHEM., vol. 272, no. 13, 28 March 1997 (1997-03-28), pages 8236 - 8242, XP002125302 * |
Also Published As
Publication number | Publication date |
---|---|
EP1073751A2 (de) | 2001-02-07 |
DE19819476C1 (de) | 2000-01-05 |
JP2002512801A (ja) | 2002-05-08 |
WO1999055876A2 (de) | 1999-11-04 |
AU4895499A (en) | 1999-11-16 |
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