WO1999045396A1 - Dispositifs de detection par chimiluminescence - Google Patents
Dispositifs de detection par chimiluminescence Download PDFInfo
- Publication number
- WO1999045396A1 WO1999045396A1 PCT/US1999/004785 US9904785W WO9945396A1 WO 1999045396 A1 WO1999045396 A1 WO 1999045396A1 US 9904785 W US9904785 W US 9904785W WO 9945396 A1 WO9945396 A1 WO 9945396A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- reagent layer
- absorbent pad
- sample
- opening
- chemiluminescence
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
Definitions
- the present invention relates to diagnostic test devices for rapid detection of analytes using chemiluminescence in a strip format.
- An advantageous shape is a thin layer lying over the opening although another shape such as a plug may be used, depending on the features of the strip. Fluid preferably moves traverse to the major surface of the reagent layer during transfer to the absorbent pad, although some device configurations may utilize lateral flow along the longest axis of a reagent layer.
- the reagent layer is a nitrocellulose membrane with antibody bound to it. Preferred in this context is an antibody that reacts with lipopolysaccharide or H7 flagellar antigen from this bacterium.
- the reagent layer need not be a "layer" per se, but may consist of a pad, rod or other shaped absorbent.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU29837/99A AU2983799A (en) | 1998-03-04 | 1999-03-04 | Chemiluminescence detection devices |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7670198P | 1998-03-04 | 1998-03-04 | |
US60/076,701 | 1998-03-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999045396A1 true WO1999045396A1 (fr) | 1999-09-10 |
Family
ID=22133690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/004785 WO1999045396A1 (fr) | 1998-03-04 | 1999-03-04 | Dispositifs de detection par chimiluminescence |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2983799A (fr) |
WO (1) | WO1999045396A1 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10058095C2 (de) * | 2000-11-03 | 2003-12-18 | Fraunhofer Ges Forschung | Vorrichtung zur Bestimmung von Analyten durch Chemilumineszenz |
US9482668B2 (en) | 2012-02-21 | 2016-11-01 | Laboratory Corporation Of America Holdings | Methods and systems for the detection of bacteria |
US10519483B2 (en) | 2012-02-21 | 2019-12-31 | Laboratory Corporation Of America Holdings | Methods and systems for rapid detection of microorganisms using infectious agents |
US11591633B2 (en) | 2019-09-11 | 2023-02-28 | Laboratory Corporation Of America Holdings | Methods and systems for the rapid detection of bacteria using recombinant bacteriophage to express an indicator subunit |
US11674124B2 (en) | 2019-06-21 | 2023-06-13 | Laboratory Corporation Of America Holdings | Methods for producing mutant bacteriophages for the detection of listeria |
US11739363B2 (en) | 2019-08-26 | 2023-08-29 | Laboratory Corporation Of America Holdings | Devices and methods for detecting microorganisms using recombinant reproduction-deficient indicator bacteriophage |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985002466A1 (fr) * | 1983-12-02 | 1985-06-06 | Vertrik Bioteknik Ab | Dispositif pour analyses chimiques et son utilisation |
EP0253371A1 (fr) * | 1986-07-15 | 1988-01-20 | Omron Tateisi Electronics Co. | Dispositif pour mesurer une substance chimique avec un couvercle facile à manipuler et une seule possibilité de sélection de la fonction |
EP0283285A2 (fr) * | 1987-03-17 | 1988-09-21 | Diagnostic Systems, Inc. | Procédé et appareil pour contrôler des substances analytiques dans des fluides |
WO1988007679A1 (fr) * | 1987-03-26 | 1988-10-06 | The Secretary Of State For Health In Her | Dispositif d'analyse et son utilisation |
EP0336454A1 (fr) * | 1984-06-01 | 1989-10-11 | Miles Inc. | Essai d'hybridation d'un acide nucléique |
WO1992002820A1 (fr) * | 1990-07-27 | 1992-02-20 | Wisconsin Alumni Research Foundation | Anticorps monoclonal specifique contre l'escherichia coli 0157:h7 et 026:h11 entero-hemorragiques et procede de detection |
-
1999
- 1999-03-04 AU AU29837/99A patent/AU2983799A/en not_active Abandoned
- 1999-03-04 WO PCT/US1999/004785 patent/WO1999045396A1/fr active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985002466A1 (fr) * | 1983-12-02 | 1985-06-06 | Vertrik Bioteknik Ab | Dispositif pour analyses chimiques et son utilisation |
EP0336454A1 (fr) * | 1984-06-01 | 1989-10-11 | Miles Inc. | Essai d'hybridation d'un acide nucléique |
EP0253371A1 (fr) * | 1986-07-15 | 1988-01-20 | Omron Tateisi Electronics Co. | Dispositif pour mesurer une substance chimique avec un couvercle facile à manipuler et une seule possibilité de sélection de la fonction |
EP0283285A2 (fr) * | 1987-03-17 | 1988-09-21 | Diagnostic Systems, Inc. | Procédé et appareil pour contrôler des substances analytiques dans des fluides |
WO1988007679A1 (fr) * | 1987-03-26 | 1988-10-06 | The Secretary Of State For Health In Her | Dispositif d'analyse et son utilisation |
WO1992002820A1 (fr) * | 1990-07-27 | 1992-02-20 | Wisconsin Alumni Research Foundation | Anticorps monoclonal specifique contre l'escherichia coli 0157:h7 et 026:h11 entero-hemorragiques et procede de detection |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10058095C2 (de) * | 2000-11-03 | 2003-12-18 | Fraunhofer Ges Forschung | Vorrichtung zur Bestimmung von Analyten durch Chemilumineszenz |
US9482668B2 (en) | 2012-02-21 | 2016-11-01 | Laboratory Corporation Of America Holdings | Methods and systems for the detection of bacteria |
US10519483B2 (en) | 2012-02-21 | 2019-12-31 | Laboratory Corporation Of America Holdings | Methods and systems for rapid detection of microorganisms using infectious agents |
US11674124B2 (en) | 2019-06-21 | 2023-06-13 | Laboratory Corporation Of America Holdings | Methods for producing mutant bacteriophages for the detection of listeria |
US11739363B2 (en) | 2019-08-26 | 2023-08-29 | Laboratory Corporation Of America Holdings | Devices and methods for detecting microorganisms using recombinant reproduction-deficient indicator bacteriophage |
US11591633B2 (en) | 2019-09-11 | 2023-02-28 | Laboratory Corporation Of America Holdings | Methods and systems for the rapid detection of bacteria using recombinant bacteriophage to express an indicator subunit |
Also Published As
Publication number | Publication date |
---|---|
AU2983799A (en) | 1999-09-20 |
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