WO1999023955A1 - Dispositif de pontage vasculaire - Google Patents

Dispositif de pontage vasculaire Download PDF

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Publication number
WO1999023955A1
WO1999023955A1 PCT/US1998/023456 US9823456W WO9923955A1 WO 1999023955 A1 WO1999023955 A1 WO 1999023955A1 US 9823456 W US9823456 W US 9823456W WO 9923955 A1 WO9923955 A1 WO 9923955A1
Authority
WO
WIPO (PCT)
Prior art keywords
body vessel
recited
shaft
diameter
vessel
Prior art date
Application number
PCT/US1998/023456
Other languages
English (en)
Inventor
Robert Lazzara
Original Assignee
Robert Lazzara
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Lazzara filed Critical Robert Lazzara
Priority to AU13788/99A priority Critical patent/AU1378899A/en
Publication of WO1999023955A1 publication Critical patent/WO1999023955A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027—Type of occlusion
    • A61B17/12036—Type of occlusion partial occlusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00243—Type of minimally invasive operation cardiac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B2017/1135—End-to-side connections, e.g. T- or Y-connections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/94—Stents retaining their form, i.e. not being deformable, after placement in the predetermined place

Definitions

  • the present invention is directed generally to methods and apparatus for halting external bleeding or loss of other bodily fluids during surgical procedures involving incision of a blood vessel. More specifically the present invention is related to methods and apparatus for reducing the risk of ischemia in the tissue downstream from a surgical incision in a blood vessel.
  • coronary artery bypass surgery is commonly required when coronary arteries narrowed by cholesterol-rich fatty deposits or plaques are unable to supply the heart muscle with a sufficient amount of blood, and as a result, the heart becomes starved for oxygen. Left untreated, coronary artery disease ultimately leads to acute myocardial infarction, commonly referred to as a heart attack.
  • a surgeon grafts a section of a healthy vessel to bypass a stenotic or partially blocked portion of a coronary artery in order to ameliorate the oxygen access to the heart muscle. While using conventional occluding devices, a surgeon encounters additional time pressure to complete the delicate surgery in order to restore blood flow and subsequent oxygenation to the heart muscle before the heart sustains irreversible damage of the very type the bypass is meant to prevent.
  • fluids such as nutrient solutions, blood, cardioplegia, contrast dye for x-rays, or drugs to the heart or other bodily organs and tissues.
  • Another object of the present invention is to provide methods and apparatus for withdrawing or sampling fluids from the surgical site.
  • a further object of the present invention is to provide methods and apparatus for facilitating momentary cardiac arrest.
  • Yet another object of the present invention is to provide methods and apparatus for performing coronary artery by-pass on a beating heart.
  • the present invention relates to a vascular shunt apparatus that comprises an elongated shaft with a hollow internal channel in fluid communication with and connected perpendicularly to flexible access tubing.
  • a valve is attached to the flexible access tubing to allow selective delivery of blood at normal body pressures, fluids, and drugs through the vascular shunt apparatus.
  • Such a feature is utilized, for example, to infuse fluids or drugs to arrest the heart for brief periods, such as from three to five seconds, which allows the surgeon a small window of time for suturing a vessel absent pulsing cardiac pressure.
  • the valve and tubing also allow withdrawal of fluids for sampling during the surgery.
  • the present invention also relates to a method for use of a vascular shunt apparatus.
  • a surgeon selects an apparatus according to the present invention which is sized to accommodate the diameter of and flow rate through a particular vessel. The surgeon then inserts the apparatus through an incision in the vessel by first sliding one end of the apparatus into the interior of the vessel and then inserting the other end.
  • the shaft of the apparatus is positioned in the vessel such that each end extends beyond the length of the incision.
  • the surgeon may then infuse a fluid or drug into the apparatus, such as for momentarily stopping the heart in coronary by-pass surgery, during which time the surgeon sutures the by-pass graft.
  • the surgeon may connect the valve to an arterial blood line from the patient.
  • the resulting connection of arterial blood through the shaft of the apparatus allows for continuous perfusion at physiologic blood pressures to prevent downstream ischemia to organs at risk following completion of the surgical procedure.
  • contrast dye can be injected into the valve and through the shaft such that x-rays can be taken to document patency and function of the completed procedure.
  • Figure 1 is a perspective view of a presently preferred embodiment of the present invention.
  • Figure 2 is a perspective view of another embodiment of the vascular shunt of the present invention depicted as being inserted into a vessel.
  • Figure 3 is a perspective view of the vascular shunt of Figure 2 situated in a vessel.
  • Figure 4 is a perspective view of the vascular shunt of Figure 2 situated in a vessel during a graft procedure.
  • Figure 5 is a perspective view of the vascular shunt of Figure 2 as it is removed from the surgical site just prior to completion of a graft.
  • the present invention relates to methods and apparatus for preventing or lessening external bleeding during surgical procedures involving incision of a blood vessel while averting ischemic damage to downstream tissues.
  • the coronary arteries which branch immediately off of the ascending aorta as it exits the left ventricle, supply oxygenated blood to the heart muscle itself. These arteries are especially prone to developing fatty deposits or plaques that narrow the available diameter for blood flow to the heart. In turn, this causes a reduction in the amount of oxygen reaching the heart muscle, and can become so severe that the vessel is actually occluded resulting in myocardial ischemia or myocardial infarction, which is commonly known as a heart attack.
  • a vessel that circumvents or "bypasses” the blockage It is possible to ameliorate this condition by attaching a vessel that circumvents or "bypasses" the blockage.
  • a vessel that circumvents or "bypasses” the blockage In a procedure known as coronary artery bypass, a length of blood vessel, usually taken from the saphenous vein in the leg, is sutured to the aorta and to the coronary artery at a location beyond the site of the occlusion.
  • a stent device basically comprises a solid shaft terminating on each end with a bulbous tip.
  • a surgeon inserts the stent into an incision in a coronary artery. With appropriately sized bulbous tips, the stent occludes flow of blood from one end of the stent to the other, both upstream flow (normal) and downstream flow (retrograde).
  • the conventional device facilitates a dry surgical field, it also prevents blood flow to the downstream tissues and potentially fosters additional ischemia or tissue damage. Furthermore, the conventional device is limited for use in small diameter blood vessels. The occlusive nature prevents the conventional device from use in larger vessels due to the enhanced probability of tissue damage from increased oxygen deprivation. Furthermore, the conventional clamps or stents necessitate additional procedures and devices for infusing fluids or drugs into the heart or peripheral tissue, or withdrawing fluids therefrom.
  • FIG. 1 illustrates features of the present invention that solve the problems encountered with conventional devices.
  • a vascular shunt apparatus in accordance with the present invention allows blood to circumvent the surgical field and to flow to the heart muscle or peripheral tissue downstream from the surgical site. Rather than forming a barrier to the blood, for example, the present invention provides a channel which maintains a virtually blood-free surgical field for the substantial duration of a procedure, without further depriving the heart muscle or peripheral tissue of much needed oxygen and other blood constituents. See, e.g., co-pending United States Patent Application Serial No. 08/720,427, the entire disclosure of which is herein incorporated by reference in its entirety, commonly owned by the assignee of the present invention.
  • the present invention additionally enables selective infusion of fluids to the heart muscle or other tissue.
  • the heart may be stopped for a brief moment by infusing drugs through the apparatus; the drugs follow the natural flow of blood to the heart muscle. Fluid flowing from the left ventricle can also be withdrawn in a similar fashion.
  • Figure 1 is a visual representation of the vascular shunt apparatus 10.
  • the vascular shunt apparatus 10 employs a shaft 12 which is elongated such that upon insertion into a vessel, the length of the shaft preferably exceeds the length of the incision in the vessel.
  • An appropriate shaft length will necessarily be determined by the length of the incision. Moreover, ease of insertion is directly proportional to the length of the shaft in comparison with the length of the incision. Therefore, in one embodiment of the present invention, a plurality of devices would be available, each with a different length, to allow the surgeon to select the appropriate size for insertion through an incision in a particular vessel.
  • the shaft 12 further comprises an external diameter which approaches the internal diameter of the vessel in question.
  • a preferred external diameter of the shaft would necessarily be determined by the internal diameter of the vessel.
  • a preferred diameter of the shaft would not be greater than that of the vessel.
  • a plurality of devices would be available, each with a shaft of a different external diameter, to allow the surgeon to select the appropriate size with respect to the internal diameter of a particular vessel.
  • the shaft would fit snugly inside the internal diameter of the vessel.
  • the external diameter of the shaft would so closely approximate the internal diameter of the vessel that the shaft would actually block the flow of blood to the surgical site, while still allowing blood to flow therethrough.
  • the shaft 12 preferentially terminates on either or both ends in the form of an enlarged tip 16.
  • the tip 16 may be an extension of or addition to the shaft 12.
  • the tip 16 should be of a size which facilitates insertion into and removal from a vessel without damaging the vascular tissue.
  • the tip should include an external diameter which approaches the internal diameter of the vessel. An optimum external diameter of the tip would necessarily be determined by the internal diameter of the vessel.
  • the tip should form a secure fit within the internal diameter of the vessel. Any space remaining between the tip and the internal vessel wall could allow blood to seep into the surgical site.
  • a tip which substantially exceeded the internal diameter of the vessel could cause impairment of insertion and removal of the apparatus, as well as traumatic vessel distension or tearing. Therefore, in a preferred embodiment of the present invention, a plurality of shunt devices would be available, each having tips with a different external diameter, to allow the surgeon to select the appropriate size with respect to the internal diameter of a particular vessel.
  • the tip preferably has a rounded and tapered shape, although various embodiments of the tip are equally effective in carrying out the intended function thereof.
  • the tip comprises a soft, flexible material and has rounded edges and surfaces to minimize potential damage to the vessel tissue layers.
  • a suitable material for the tip by way of example and not limitation, is silicone.
  • the tip may additionally comprise radiopaque material such that it can be easily located if necessary.
  • each tip opens into a hollow internal channel 14 running the length of shaft 12.
  • the hollow internal channel 14 preferably accommodates the rate or amount of blood flow through a particular vessel; larger vessels necessarily require greater shunting capabilities through the hollow internal channel than smaller vessels. Therefore, in one embodiment of the present invention, a plurality of devices would be available, each with a hollow internal channel of a different diameter, to allow the surgeon to select the appropriate size for the rate and amount of blood flow through a particular vessel.
  • the hollow internal channel 14 extends into and through the tip 16. Each tip also opens into the interior of the vessel, allowing blood or other fluids to pass freely through the hollow internal channel from one tip through the shaft and out the other tip to the tissue downstream.
  • the hollow internal channel 14 is further in fluid communication with access tubing 18.
  • Access tubing 18 is preferably connected to the shaft 12 such that access tubing and the shaft form one molded piece. Such a connection increases the strength of the device, and decreases the likelihood of weakening or tearing at the intersection 26 of access tubing with the shaft.
  • Access tubing 18 allows selective infusion or withdrawal of fluids from the surgical site. For example, in a coronary bypass procedure, infusion of selected drug solutions through access tubing can stop the heart for very brief periods such that the surgeon can perform sutures without the pressure of blood flowing through the vessel, yet also without further compromising the tissue of the heart as may occur in longer duration hear stop procedures.
  • access tubing allows selective infusion of dyes, fluids, or any other material as per the discretion of the surgeon.
  • a surgeon may wish to withdraw fluids through access tubing 18 for procedures such as, but not limited to, ascertaining cardiac output or blood gas analysis.
  • access tubing 18 is connected to a valve 22, which further facilitates administration or withdrawal of selected fluids.
  • a valve 22 which further facilitates administration or withdrawal of selected fluids.
  • a surgeon may wish to connect a source of drug solution to access tubing 18 through valve 22 by way of proximal opening 24.
  • the valve When the valve is in the closed position, the drug solution does not flow to the heart tissue.
  • the surgeon can quickly and easily open the valve and deliver a small amount of drag solution to the heart such that the heart stops only momentarily.
  • the valve offers the surgeon unique control over the heart and surgical site.
  • the intersection 26 of access tubing to the shaft 12 may also serve as a positioning mechanism which assists the surgeon in proper placement of the apparatus in a vessel.
  • the tubing connects to the shaft at or near the midpoint of the shaft. Upon attachment at or near the midpoint of the shaft, the tubing may aid the surgeon in determining relative distances with respect to the vessel and the apparatus therein.
  • the tubing additionally may serve as a location marker to prevent loss of the apparatus in a vessel.
  • a tether 28 may be affixed to the shaft in the manner shown in copending application 08/720,427, incorporated herein by reference.
  • Tether 28 additionally serves as a location marker to prevent loss of the apparatus in a vessel.
  • tether 28 diverts the surgeon from pulling on the access tubing 18 attached around the shaft 12 which helps prevent separation at the shaft-tubing intersection 26.
  • the method for use of the present invention is substantially similar to that disclosed in copending patent application Serial No. 08/720,427 incorporated herein by reference.
  • Figures 2-5 illustrate a presently preferred embodiment of the method for using the vascular shunt apparatus.
  • the present disclosure shall be directed to the use of a vascular shunt apparatus in connection with a coronary artery bypass procedure although it should be understood that other procedures also benefit from such an apparatus.
  • the vascular shunt 10 is inserted through an incision 30 in a vessel 20 by sliding the downstream end 32 into the interior 21 of the vessel 20.
  • the shaft 12 is then extended into the remote space of the vessel 20.
  • the surgeon may insert the upstream end 33 when the length of the incision 30 so allows.
  • the surgeon then may slide the vascular shunt 10 upstream until the attachment point of the tether 28 and intersection of the tubing 18 is visible at the incision 30. If there is an optimal fit of the apparatus in the vessel, the blood should flow through the hollow internal channel of the vascular shunt 10 without leaking into the surgical site.
  • Figures 3-4 illustrate the vascular shunt appropriately positioned in situ.
  • Figure 4 illustrates a bypass graft at a moment just prior to completion wherein the surgeon leaves just enough room in the graft 36 to allow removal of the vascular shunt 10.
  • fluids can be selectively infused through or withdrawn from the apparatus through valve 22 and access tubing 18.
  • Figure 5 demonstrates the removal of the vascular shunt 10 before the surgeon completes the final sutures.
  • the surgeon removes the vascular shunt 10 by sliding the downstream end 32 (not shown in Figure 5) distally from the site of the remaining sutures and the gap in the graft 36 until the upstream end 33 is proximal to the suture site.
  • the surgeon can then remove the vascular shunt 10 by sliding the proximal upstream end 33 out through the slight gap in the graft 36 and then removing the remaining shaft 12 and downstream end 32.
  • the surgeon can resume stitching the remaining sutures necessary to close and complete the graft.
  • the invention disclosed herein may alternatively be utilized by inserting only one end of the apparatus downstream from the blockage in the vessel. By closing off the upstream opening in the apparatus, blood or other fluids can then be selectively infused to heart. Such an alternative procedure is useful when a blockage is so occlusive that it will not accommodate the upstream end of the apparatus.
  • the vascular shunt apparatus can be used in surgical sites to allow blood flow to tissues that would otherwise be deprived of oxygen and other vital blood constituents for the duration of coronary or peripheral bypass surgery.
  • the additional advantages derived from this shunt mechanism allow a dry field for the surgeon, and also alleviate the time pressure inherent in any surgery wherein the flow of blood is occluded for substantial durations.
  • other types of procedures that preferably include or necessarily require a dry field without the occlusive effects of the prior art, will benefit from this invention.
  • the vascular shunt apparatus can also be utilized as a stent to open a vessel during a procedure.
  • the apparatus can be utilized with x- ray contrast dye for taking x-rays after the completion of a procedure to document function and patency.
  • the apparatus of the present invention may alternatively be utilized to inject radiographic contrast dye into vessels for the performance of intra-operative angiography.
  • the apparatus may act as a guide for access to coronary vessels for the performance of intra-operative angioplasty and other types of interventional intra-operative cardiologic procedures.
  • the present invention may be embodied in other specific forms without departing from its spirit or essential characteristics.
  • the described embodiments are to be considered in all respects only as illustrative and not restrictive.
  • the scope of the invention is, therefore, indicated by the appended claims rather than by the foregoing description. All changes which come within the meaning and range of equivalency of the claims are to be embraced within their scope.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne des techniques et des dispositifs utiles pour prévenir ou pour réduire les hémorragies externes ou la perte d'autres fluides corporels durant des interventions chirurgicales impliquant l'incision d'un vaisseau sanguin. Après insertion dans un vaisseau sanguin, une tige allongée creusée d'une lumière permet au sang ou à l'autre fluide de s'écouler normalement, ce qui évite l'apparition d'une ischémie dans les organes et les tissus situés en aval du champ opératoire. Un clapet est fixé sur la tige du dispositif par l'intermédiaire d'un tube flexible. Le clapet et le tube sont en communication fluidique avec la lumière du dispositif et permettent d'introduire sélectivement des fluides ou des médicaments par ledit dispositif. Le tube est utilisé, par exemple, pour injecter des fluides ou des médicaments, ou bien pour prélever un échantillon de fluide durant l'intervention. L'invention concerne également une technique permettant d'utiliser un dispositif de pontage vasculaire. Selon un aspect de l'invention, un chirurgien choisit un dispositif ayant une taille qui lui permet de s'adapter au diamètre et au débit d'un certain vaisseau. Puis il insère le dispositif par une incision dans ledit vaisseau, de façon que chaque extrémité dépasse la longueur de l'incision. Il peut ensuite injecter un fluide ou un médicament dans le dispositif, par exemple pour arrêter momentanément le coeur durant une intervention de pontage coronarien le temps de suturer un greffon de pontage. La présente invention peut également être utilisée comme stent pour agrandir le diamètre interne d'un vaisseau durant une intervention.
PCT/US1998/023456 1997-11-12 1998-11-04 Dispositif de pontage vasculaire WO1999023955A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU13788/99A AU1378899A (en) 1997-11-12 1998-11-04 Vascular shunt apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96913997A 1997-11-12 1997-11-12
US08/969,139 1997-11-12

Publications (1)

Publication Number Publication Date
WO1999023955A1 true WO1999023955A1 (fr) 1999-05-20

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ID=25515238

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/023456 WO1999023955A1 (fr) 1997-11-12 1998-11-04 Dispositif de pontage vasculaire

Country Status (2)

Country Link
AU (1) AU1378899A (fr)
WO (1) WO1999023955A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1192906A1 (fr) * 2000-09-28 2002-04-03 Nipro Corporation Shunt intra-artériel et procédé d'utilisation
EP1339445A2 (fr) * 2000-10-27 2003-09-03 Pulmonx Procedes et dispositifs destines a occlure et a aspirer des segments de tissu pulmonaire
GB2421185A (en) * 2004-08-18 2006-06-21 Al Khaddour Ahmad T shaped tubing for use in anastomosis

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230119A (en) * 1978-12-01 1980-10-28 Medical Engineering Corp. Micro-hemostat
US4547187A (en) * 1983-05-06 1985-10-15 Thomas R. Kelly, M.D., Inc. Inflatable cholangiocath and method for cholangiography therewith
US4731055A (en) * 1986-08-25 1988-03-15 Becton, Dickinson And Company Blood flow conduit
WO1992019161A1 (fr) 1991-04-30 1992-11-12 Bio-Vascular, Inc. Sonde vasculaire
WO1997029716A1 (fr) * 1996-02-13 1997-08-21 Scimed Life Systems, Inc. Appareil endovasculaire
EP0791332A1 (fr) * 1996-02-20 1997-08-27 Cardiothoracic Systems, Inc. Un dispositif de perfusion pour maintenir le flux de sang dans un vesseau pendant und procédé d'anastomose

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230119A (en) * 1978-12-01 1980-10-28 Medical Engineering Corp. Micro-hemostat
US4547187A (en) * 1983-05-06 1985-10-15 Thomas R. Kelly, M.D., Inc. Inflatable cholangiocath and method for cholangiography therewith
US4731055A (en) * 1986-08-25 1988-03-15 Becton, Dickinson And Company Blood flow conduit
WO1992019161A1 (fr) 1991-04-30 1992-11-12 Bio-Vascular, Inc. Sonde vasculaire
WO1997029716A1 (fr) * 1996-02-13 1997-08-21 Scimed Life Systems, Inc. Appareil endovasculaire
EP0791332A1 (fr) * 1996-02-20 1997-08-27 Cardiothoracic Systems, Inc. Un dispositif de perfusion pour maintenir le flux de sang dans un vesseau pendant und procédé d'anastomose

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1192906A1 (fr) * 2000-09-28 2002-04-03 Nipro Corporation Shunt intra-artériel et procédé d'utilisation
EP1339445A2 (fr) * 2000-10-27 2003-09-03 Pulmonx Procedes et dispositifs destines a occlure et a aspirer des segments de tissu pulmonaire
EP1339445A4 (fr) * 2000-10-27 2004-07-14 Pulmonx Procedes et dispositifs destines a occlure et a aspirer des segments de tissu pulmonaire
US6997918B2 (en) 2000-10-27 2006-02-14 Pulmonx Methods and devices for obstructing and aspirating lung tissue segments
GB2421185A (en) * 2004-08-18 2006-06-21 Al Khaddour Ahmad T shaped tubing for use in anastomosis
GB2421185B (en) * 2004-08-18 2010-12-15 Al Khaddour Ahmad T shaped tubing for coronary anastomosis

Also Published As

Publication number Publication date
AU1378899A (en) 1999-05-31

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