WO1999003993A3 - Suppresseurs de signalement de cytokine et reactifs correspondants - Google Patents
Suppresseurs de signalement de cytokine et reactifs correspondants Download PDFInfo
- Publication number
- WO1999003993A3 WO1999003993A3 PCT/US1998/014544 US9814544W WO9903993A3 WO 1999003993 A3 WO1999003993 A3 WO 1999003993A3 US 9814544 W US9814544 W US 9814544W WO 9903993 A3 WO9903993 A3 WO 9903993A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- suppressors
- cytokine signaling
- related reagents
- reagents
- molecules
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU84845/98A AU8484598A (en) | 1997-07-18 | 1998-07-17 | Suppressors of cytokine signaling; related reagents |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5315397P | 1997-07-18 | 1997-07-18 | |
US5324497P | 1997-07-18 | 1997-07-18 | |
US60/053,153 | 1997-07-18 | ||
US60/053,244 | 1997-07-18 | ||
US5580497P | 1997-08-15 | 1997-08-15 | |
US5585397P | 1997-08-15 | 1997-08-15 | |
US60/055,853 | 1997-08-15 | ||
US60/055,804 | 1997-08-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999003993A2 WO1999003993A2 (fr) | 1999-01-28 |
WO1999003993A3 true WO1999003993A3 (fr) | 1999-06-03 |
Family
ID=27489542
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/014545 WO1999003994A1 (fr) | 1997-07-18 | 1998-07-16 | Suppresseurs de signalement de cytokine; socs16 et reactifs correspondants |
PCT/US1998/014544 WO1999003993A2 (fr) | 1997-07-18 | 1998-07-17 | Suppresseurs de signalement de cytokine et reactifs correspondants |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/014545 WO1999003994A1 (fr) | 1997-07-18 | 1998-07-16 | Suppresseurs de signalement de cytokine; socs16 et reactifs correspondants |
Country Status (2)
Country | Link |
---|---|
AU (2) | AU8484698A (fr) |
WO (2) | WO1999003994A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2308785T3 (es) * | 1996-11-01 | 2008-12-01 | The Walter And Eliza Hall Institute Of Medical Research | Agentes terapeuticos y diagnosticos capaces de modular la sensibilidad celular a citoquinas. |
US6905842B1 (en) | 1996-11-01 | 2005-06-14 | The Walter And Eliza Hall Institute Of Medical Research | Therapeutic and diagnostic agents |
EP0877030A3 (fr) * | 1997-05-07 | 2001-05-23 | Smithkline Beecham Corporation | Gène en réponse primaire à l'EPO 1 (EPRG1) |
EP0970215A1 (fr) * | 1997-11-03 | 2000-01-12 | Incyte Pharmaceuticals, Inc. | Suppresseur de la signalisation cytokinaire |
EP0953636A3 (fr) | 1998-03-23 | 2000-03-29 | Smithkline Beecham Plc | Régulateurs du signal de cytokines |
US7078174B1 (en) | 1998-12-21 | 2006-07-18 | The Walter & Eliza Hall Institute Of Medical Research | Screening methods using SOCS box-containing peptides |
GB9918680D0 (en) * | 1999-08-09 | 1999-10-13 | Medical Res Council | Polypeptide |
JP2003520577A (ja) * | 1999-10-21 | 2003-07-08 | スミスクライン・ビーチャム・コーポレイション | Epo一次応答遺伝子1、eprg1 |
GB2373502A (en) * | 2000-11-08 | 2002-09-25 | Smithkline Beecham Corp | Suppressor of cytokine signalling 4 (SOCS4) |
WO2002055699A2 (fr) * | 2000-12-14 | 2002-07-18 | Upjohn Co | Nouveau socs (suppresseur de la transmission des signaux par les cytokines) |
US20060194275A1 (en) * | 2001-04-13 | 2006-08-31 | Incyte Corporation | Transporter and ion channels |
US7348139B1 (en) | 2001-04-13 | 2008-03-25 | The Johns Hopkins University School Of Medicine | SOCS-1 gene methylation in cancer |
EP1734982A4 (fr) | 2004-03-04 | 2009-08-05 | Univ Vanderbilt | Polypeptides socs pour inhiber la signalisation induite par la cytokine |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998020023A1 (fr) * | 1996-11-01 | 1998-05-14 | The Walter And Eliza Hall Institute Of Medical Research | Agents therapeutiques et diagnostiques capables de moduler la receptivite cellulaire aux cytokines |
-
1998
- 1998-07-16 WO PCT/US1998/014545 patent/WO1999003994A1/fr active Application Filing
- 1998-07-16 AU AU84846/98A patent/AU8484698A/en not_active Abandoned
- 1998-07-17 WO PCT/US1998/014544 patent/WO1999003993A2/fr active Application Filing
- 1998-07-17 AU AU84845/98A patent/AU8484598A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998020023A1 (fr) * | 1996-11-01 | 1998-05-14 | The Walter And Eliza Hall Institute Of Medical Research | Agents therapeutiques et diagnostiques capables de moduler la receptivite cellulaire aux cytokines |
Non-Patent Citations (6)
Title |
---|
A. YOSHIMURA ET AL: "A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to Tyrosine-phosphorylated interleukin-3 and erythropoietin", EMBO JOURNAL., vol. 14, no. 12, 1995, EYNSHAM, OXFORD GB, pages 2816 - 2826, XP002088456 * |
D.J. HILTON ET AL: "Twenty proteins containing a C-terminal SOCS box form five structural classes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., vol. 95, January 1998 (1998-01-01), WASHINGTON US, pages 114 - 119, XP002085497 * |
M. MASUHARA ET AL: "Cloning and characterization of novel CIS family genes", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 239, October 1997 (1997-10-01), ORLANDO, FL US, pages 439 - 446, XP002088457 * |
R. STARR ET AL: "A family of cytokine-inducible inhibitors of signalling", NATURE., vol. 387, no. 6636, 26 June 1997 (1997-06-26), LONDON GB, pages 917 - 921, XP002085491 * |
T. NAKA ET AL: "Structure and function of a new STAT-induced STAT inhibitor", NATURE., vol. 387, no. 6636, 26 June 1997 (1997-06-26), LONDON GB, pages 924 - 929, XP002088455 * |
T.A ENDO ET AL: "A new protein containing an SH2 domain that inhibits JAK kinases", NATURE., vol. 387, no. 6636, 26 June 1997 (1997-06-26), LONDON GB, pages 921 - 924, XP002085492 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999003994A1 (fr) | 1999-01-28 |
AU8484598A (en) | 1999-02-10 |
AU8484698A (en) | 1999-02-10 |
WO1999003993A2 (fr) | 1999-01-28 |
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