WO1998057667B1 - Procedes d'imagerie photoacoustique - Google Patents
Procedes d'imagerie photoacoustiqueInfo
- Publication number
- WO1998057667B1 WO1998057667B1 PCT/GB1998/001751 GB9801751W WO9857667B1 WO 1998057667 B1 WO1998057667 B1 WO 1998057667B1 GB 9801751 W GB9801751 W GB 9801751W WO 9857667 B1 WO9857667 B1 WO 9857667B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- absorbing
- light
- radiation
- particles
- contrast agent
- Prior art date
Links
- 238000003384 imaging method Methods 0.000 title 1
- 239000002872 contrast media Substances 0.000 claims abstract 3
- 230000001939 inductive effect Effects 0.000 claims abstract 3
- 239000002245 particle Substances 0.000 claims 4
- 239000000839 emulsion Substances 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 229910002804 graphite Inorganic materials 0.000 claims 1
- 239000010439 graphite Substances 0.000 claims 1
- 230000002209 hydrophobic Effects 0.000 claims 1
- 239000007764 o/w emulsion Substances 0.000 claims 1
- 239000000049 pigment Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Abstract
L'invention concerne un procédé de génération d'une image d'un corps animé d'animal humain, ou non humain, ou d'une partie de ce corps. Ce procédé consiste à administrer audit corps un agent de contraste physiologiquement tolérable renfermant un composant absorbant un rayonnement et/ou un composant générateur de pression; à exposer ledit corps au rayonnement; à déceler les ondes de pression générées dans ledit corps par ledit rayonnement; et à générer à partir de ces ondes une image optoacoustique d'au moins une partie dudit corps auquel on a administré l'agent de contraste.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98930870A EP0996469B1 (fr) | 1997-06-16 | 1998-06-16 | Procedes d'imagerie photoacoustique |
JP50396399A JP4436461B2 (ja) | 1997-06-16 | 1998-06-16 | 光音響画像形成方法 |
DE69817360T DE69817360T2 (de) | 1997-06-16 | 1998-06-16 | Verfahren zur photoakustische bilderzeugung |
AT98930870T ATE247491T1 (de) | 1997-06-16 | 1998-06-16 | Verfahren zur photoakustische bilderzeugung |
AU81158/98A AU8115898A (en) | 1997-06-16 | 1998-06-16 | Methods of photoacoustic imaging |
US09/458,008 US6662040B1 (en) | 1997-06-16 | 1999-12-10 | Methods of photoacoustic imaging |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9712524.9 | 1997-06-16 | ||
GBGB9712524.9A GB9712524D0 (en) | 1997-06-16 | 1997-06-16 | Method |
US4990997P | 1997-06-18 | 1997-06-18 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/458,008 Continuation US6662040B1 (en) | 1997-06-16 | 1999-12-10 | Methods of photoacoustic imaging |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998057667A1 WO1998057667A1 (fr) | 1998-12-23 |
WO1998057667B1 true WO1998057667B1 (fr) | 1999-02-18 |
Family
ID=10814249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1998/001751 WO1998057667A1 (fr) | 1997-06-16 | 1998-06-16 | Procedes d'imagerie photoacoustique |
Country Status (9)
Country | Link |
---|---|
US (1) | US6662040B1 (fr) |
EP (1) | EP0996469B1 (fr) |
JP (1) | JP4436461B2 (fr) |
AT (1) | ATE247491T1 (fr) |
AU (1) | AU8115898A (fr) |
DE (1) | DE69817360T2 (fr) |
ES (1) | ES2206951T3 (fr) |
GB (1) | GB9712524D0 (fr) |
WO (1) | WO1998057667A1 (fr) |
Families Citing this family (58)
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US6630570B1 (en) | 1999-04-09 | 2003-10-07 | Insitut für Diagnostikforschung GmbH | Short-chain peptide-dye conjugates as contrast media for optical diagnosis |
DE19917713A1 (de) * | 1999-04-09 | 2000-10-19 | Diagnostikforschung Inst | Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik |
US7175953B2 (en) | 1999-04-09 | 2007-02-13 | Institute Fuer Diagnostik Forschung | Short-warp peptide-dye conjugate as contrast agent for optical diagnostic |
JP2001299676A (ja) * | 2000-04-25 | 2001-10-30 | Fuji Photo Film Co Ltd | センチネルリンパ節検出方法および検出システム |
IL138073A0 (en) | 2000-08-24 | 2001-10-31 | Glucon Inc | Photoacoustic assay and imaging system |
DK1593091T3 (da) | 2003-01-25 | 2013-10-28 | Seno Medical Instr Inc | Optoakustisk afbildning med høj kontrast ved anvendelse af ikke-sfæriske nanopartikler |
EA015095B1 (ru) * | 2005-05-24 | 2011-06-30 | Бейкер Хьюз Инкорпорейтед | Способ и устройство определения характеристик коллектора с использованием фотоакустической спектроскопии |
US7387021B2 (en) * | 2005-05-24 | 2008-06-17 | Baker Hughes Incorporated | Method and apparatus for reservoir characterization using photoacoustic spectroscopy |
CA2610070A1 (fr) | 2005-05-26 | 2006-11-30 | Araz Yacoubian | Imageur a large bande |
US20070015992A1 (en) * | 2005-06-30 | 2007-01-18 | General Electric Company | System and method for optoacoustic imaging |
WO2007100937A2 (fr) * | 2006-01-19 | 2007-09-07 | The Regents Of The University Of Michigan | Système et procédé pour tomographie photo-acoustique spectroscopique |
CA2671101C (fr) * | 2006-01-20 | 2016-06-14 | Seno Medical Instruments, Inc. | Tomographie opto-acoustique quantitative a contraste amelioe |
US20080123083A1 (en) * | 2006-11-29 | 2008-05-29 | The Regents Of The University Of Michigan | System and Method for Photoacoustic Guided Diffuse Optical Imaging |
US20080173093A1 (en) * | 2007-01-18 | 2008-07-24 | The Regents Of The University Of Michigan | System and method for photoacoustic tomography of joints |
US20080221647A1 (en) * | 2007-02-23 | 2008-09-11 | The Regents Of The University Of Michigan | System and method for monitoring photodynamic therapy |
US20080228073A1 (en) * | 2007-03-12 | 2008-09-18 | Silverman Ronald H | System and method for optoacoustic imaging of peripheral tissues |
US20080241065A1 (en) * | 2007-03-27 | 2008-10-02 | Benaron David A | Systems and methods for the detection and analysis of in vivo circulating cells, entities, and nanobots |
WO2009064030A1 (fr) * | 2007-11-16 | 2009-05-22 | Canon Kabushiki Kaisha | Agent d'imagerie photoacoustique |
CN101946171B (zh) * | 2007-12-14 | 2014-03-12 | 拜奥蒂乌姆股份有限公司 | 荧光化合物 |
JP5284129B2 (ja) * | 2008-02-06 | 2013-09-11 | キヤノン株式会社 | イメージング装置、及び解析方法 |
EP2110076A1 (fr) * | 2008-02-19 | 2009-10-21 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Procédé et dispositif pour l'imagerie de modalité à onde double à champ rapproché |
EP2344019B1 (fr) | 2008-07-25 | 2013-11-27 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Tomographie opto-acoustique multi-spectrale quantitative (msot) de biomarqueurs tissulaires |
US8426933B2 (en) * | 2008-08-08 | 2013-04-23 | Araz Yacoubian | Broad spectral band sensor |
JP5241465B2 (ja) * | 2008-12-11 | 2013-07-17 | キヤノン株式会社 | 光音響イメージング装置および光音響イメージング方法 |
EP2410990A4 (fr) * | 2009-03-19 | 2015-05-20 | Marval Biosciences Inc | Compositions et procédés d'amélioration des contrastes en imagerie |
US9271654B2 (en) | 2009-06-29 | 2016-03-01 | Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) | Thermoacoustic imaging with quantitative extraction of absorption map |
US20110016962A1 (en) * | 2009-07-21 | 2011-01-27 | Baker Hughes Incorporated | Detector for Characterizing a Fluid |
WO2011012274A1 (fr) | 2009-07-27 | 2011-02-03 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Dispositif dimagerie et procédé pour limagerie opto-acoustique de petits animaux |
US8658434B2 (en) * | 2009-10-28 | 2014-02-25 | Biotium, Inc. | Fluorescent pyrene compounds |
US10634741B2 (en) | 2009-12-04 | 2020-04-28 | Endomagnetics Ltd. | Magnetic probe apparatus |
US9427186B2 (en) * | 2009-12-04 | 2016-08-30 | Endomagnetics Ltd. | Magnetic probe apparatus |
US9610367B2 (en) * | 2010-08-24 | 2017-04-04 | Canon Kabushiki Kaisha | Particle and contrast agent having the particle |
BR112013015814A2 (pt) * | 2010-12-22 | 2018-05-15 | Koninl Philips Electronics Nv | agente de contraste de formação de imagem, segundo agente de contraste fotoacústico, método, método para formar, como uma mistura, um segundo agente de contraste fotoacústico, dispositivo configurado para localizar uma ou mais localizações de uma fonte de energia acústica, dispositivo configurado para utilizar atrasos de tempo e direções do ultrassom recebido de uma pluralidade de bolhas para localizar uma fonte de energia acústica, produto de software de computador para formação de imagem, sinal e método para gerar o sinal |
WO2012136813A2 (fr) * | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents pour un diagnostic par radar médical |
WO2012176093A1 (fr) * | 2011-06-20 | 2012-12-27 | Koninklijke Philips Electronics N.V. | Imagerie d'agent |
US8843190B2 (en) * | 2011-07-21 | 2014-09-23 | The Board Of Trustees Of The Leland Stanford Junior University | Medical screening and diagnostics based on air-coupled photoacoustics |
WO2014013732A1 (fr) * | 2012-07-20 | 2014-01-23 | Canon Kabushiki Kaisha | Composé et milieu de contraste d'imagerie photoacoustique le contenant |
CN104470546B (zh) | 2012-07-20 | 2018-02-27 | 佳能株式会社 | 化合物和含有所述化合物的光声成像造影剂 |
EP2742854B1 (fr) | 2012-12-11 | 2021-03-10 | iThera Medical GmbH | Dispositif portatif et procédé pour imagerie opto-acoustique tomographique d'un objet |
EP2754388B1 (fr) | 2013-01-15 | 2020-09-09 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH | Système et procédé pour imagerie opto-acoustique à haut débit de meilleure qualité d'un objet |
EP2968560B1 (fr) | 2013-03-11 | 2020-04-29 | Endomagnetics Ltd. | Solutions hypoosmotiques pour une détection de ganglion lymphatique |
US9234877B2 (en) | 2013-03-13 | 2016-01-12 | Endomagnetics Ltd. | Magnetic detector |
US9239314B2 (en) | 2013-03-13 | 2016-01-19 | Endomagnetics Ltd. | Magnetic detector |
US11077214B2 (en) * | 2013-05-24 | 2021-08-03 | University Health Network | Multimodal CT/optical agents |
US10456044B2 (en) | 2013-11-22 | 2019-10-29 | Massachusetts Institute Of Technology | Systems and methods for generating non-contact ultrasound images using photoacoustic energy |
WO2015084270A1 (fr) | 2013-12-06 | 2015-06-11 | Agency For Science, Technology And Research | Procédé d'imagerie d'un tissu vivant |
CN107148265B (zh) * | 2014-07-02 | 2019-04-05 | 纽约州立大学研究基金会 | 具有高的负载物与表面活性剂比率的剥离了表面活性剂的胶束组合物 |
EP3188764B1 (fr) | 2014-10-24 | 2023-08-23 | Canon Kabushiki Kaisha | Polymère et agent de contraste pour l'imagerie photoacoustique comportant le polymère |
KR101638588B1 (ko) * | 2015-04-23 | 2016-07-12 | 포항공과대학교 산학협력단 | 소화기관의 비침습적 이미징 장치 |
WO2016193753A2 (fr) | 2015-06-04 | 2016-12-08 | Endomagnetics Ltd. | Matériaux et formes de marqueur pour localisation à marqueur magnétique (mml) |
US10602931B2 (en) | 2016-03-14 | 2020-03-31 | Massachusetts Institute Of Technology | System and method for non-contact ultrasound with enhanced safety |
ITUA20164756A1 (it) * | 2016-06-29 | 2017-12-29 | Bio On Spa | Nanoparticelle polimeriche biocompatibili contenenti nanostrutture metalliche funzionali, processo di preparazione e relativo uso in campo diagnostico e/o terapeutico. |
US10780185B2 (en) | 2017-01-30 | 2020-09-22 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential |
DE102017201543A1 (de) * | 2017-01-31 | 2018-08-02 | Siemens Healthcare Gmbh | Quantifizierung von Blutverlust auf Basis einer Computertomographie mit einem direkt konvertierenden Detektor |
CN106990048B (zh) * | 2017-05-18 | 2020-04-14 | 厦门大学 | 一种基于光声成像技术的活细菌检测方法 |
US11082127B1 (en) * | 2019-03-07 | 2021-08-03 | Massachusetts Institute Of Technology | Methods and apparatus for acoustic laser communications |
CN109985252A (zh) * | 2019-05-10 | 2019-07-09 | 南京鼓楼医院 | 一种新型双模态小分子造影剂及其制备方法与应用 |
EP3932295A1 (fr) * | 2020-06-30 | 2022-01-05 | Universität Zürich | Procédé de tomographie opto-acoustique d'un organisme vivant, images opto-acoustiques 2d ou 3d, flux sanguin 2d ou 3d et images de fluence photonique et agent photoabsorbant pour l'utilisation dans un procédé opto-acoustique |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4267732A (en) * | 1978-11-29 | 1981-05-19 | Stanford University Board Of Trustees | Acoustic microscope and method |
US4442843A (en) * | 1980-11-17 | 1984-04-17 | Schering, Ag | Microbubble precursors and methods for their production and use |
US4385634A (en) * | 1981-04-24 | 1983-05-31 | University Of Arizona Foundation | Radiation-induced thermoacoustic imaging |
SE8804074D0 (sv) * | 1988-11-10 | 1988-11-10 | Pharmacia Ab | Sensorenhet och dess anvaendning i biosensorsystem |
JP3260884B2 (ja) * | 1993-02-05 | 2002-02-25 | キヤノン株式会社 | 標識複合体、それを用いる分析法、生体関連物質の検出および定量の方法 |
DE4445065A1 (de) * | 1994-12-07 | 1996-06-13 | Diagnostikforschung Inst | Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung |
US5840023A (en) * | 1996-01-31 | 1998-11-24 | Oraevsky; Alexander A. | Optoacoustic imaging for medical diagnosis |
US6309352B1 (en) * | 1996-01-31 | 2001-10-30 | Board Of Regents, The University Of Texas System | Real time optoacoustic monitoring of changes in tissue properties |
US6022309A (en) * | 1996-04-24 | 2000-02-08 | The Regents Of The University Of California | Opto-acoustic thrombolysis |
CA2213935C (fr) * | 1996-08-27 | 2002-10-01 | Tokyo Gas Co., Ltd. | Agent diagnostique pour le diabete |
US6123923A (en) * | 1997-12-18 | 2000-09-26 | Imarx Pharmaceutical Corp. | Optoacoustic contrast agents and methods for their use |
-
1997
- 1997-06-16 GB GBGB9712524.9A patent/GB9712524D0/en active Pending
-
1998
- 1998-06-16 WO PCT/GB1998/001751 patent/WO1998057667A1/fr active IP Right Grant
- 1998-06-16 AU AU81158/98A patent/AU8115898A/en not_active Abandoned
- 1998-06-16 DE DE69817360T patent/DE69817360T2/de not_active Expired - Lifetime
- 1998-06-16 EP EP98930870A patent/EP0996469B1/fr not_active Expired - Lifetime
- 1998-06-16 AT AT98930870T patent/ATE247491T1/de not_active IP Right Cessation
- 1998-06-16 JP JP50396399A patent/JP4436461B2/ja not_active Expired - Fee Related
- 1998-06-16 ES ES98930870T patent/ES2206951T3/es not_active Expired - Lifetime
-
1999
- 1999-12-10 US US09/458,008 patent/US6662040B1/en not_active Expired - Fee Related
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