WO1998055616A3 - Brca2 locus-associated protein - Google Patents

Brca2 locus-associated protein Download PDF

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Publication number
WO1998055616A3
WO1998055616A3 PCT/US1998/011774 US9811774W WO9855616A3 WO 1998055616 A3 WO1998055616 A3 WO 1998055616A3 US 9811774 W US9811774 W US 9811774W WO 9855616 A3 WO9855616 A3 WO 9855616A3
Authority
WO
WIPO (PCT)
Prior art keywords
brca2
associated protein
lap
provides
brca2 locus
Prior art date
Application number
PCT/US1998/011774
Other languages
French (fr)
Other versions
WO1998055616A2 (en
Inventor
Jennifer L Hillman
Karl J Guegler
Purvi Shah
Original Assignee
Incyte Pharma Inc
Jennifer L Hillman
Karl J Guegler
Purvi Shah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Jennifer L Hillman, Karl J Guegler, Purvi Shah filed Critical Incyte Pharma Inc
Priority to AU80607/98A priority Critical patent/AU8060798A/en
Publication of WO1998055616A2 publication Critical patent/WO1998055616A2/en
Publication of WO1998055616A3 publication Critical patent/WO1998055616A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides a human BRCA2 locus-associated protein (BRCA2-Lap) and polynucleotides which identify and encode BRCA2-Lap. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of BRCA2-Lap.
PCT/US1998/011774 1997-06-06 1998-06-05 Brca2 locus-associated protein WO1998055616A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU80607/98A AU8060798A (en) 1997-06-06 1998-06-05 Brca2 locus-associated protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87069297A 1997-06-06 1997-06-06
US08/870,692 1997-06-06

Publications (2)

Publication Number Publication Date
WO1998055616A2 WO1998055616A2 (en) 1998-12-10
WO1998055616A3 true WO1998055616A3 (en) 1999-03-04

Family

ID=25355921

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/011774 WO1998055616A2 (en) 1997-06-06 1998-06-05 Brca2 locus-associated protein

Country Status (2)

Country Link
AU (1) AU8060798A (en)
WO (1) WO1998055616A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110950958B (en) * 2019-11-08 2022-07-22 江苏大学 anti-BRCA 2 monoclonal antibody and application thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Emhum2 Database Entry Hsu50523 Accession number U50523; 11 September 1996 COUCH F.J. ET AL. *
FERGUS J. COUCH ET AL.: "Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13", GENOMICS, vol. 36, 15 August 1996 (1996-08-15), pages 86 - 99, XP000647994 *
JACOB A ET AL: "ISOLATION OF EXPRESSED SEQUENCES THAT INCLUDE A GENE FOR FAMILIAL BREAST CANCER (BRCA2) AND OTHER NOVEL TRANSCRIPTS FROM A FIVE MEGABASE REGION ON CHROMOSOME 13Q12", ONCOGENE, vol. 13, no. 1, 4 July 1996 (1996-07-04), pages 213 - 221, XP000618761 *
MIEKE ASCHUTTE ET AL.: "Identification by representational difference analysis of a homozyguous deletion in pancreatic carcinoma that lies within the BRCA2 region", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 92, no. 13, 20 June 1995 (1995-06-20), WASHINGTON US, pages 5950 - 5954, XP002029511 *
Trhum Database Entry Q92801 Accession number Q92801; 1 February 1997 COUCH F.J. ET AL. *

Also Published As

Publication number Publication date
AU8060798A (en) 1998-12-21
WO1998055616A2 (en) 1998-12-10

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