WO1998036782A3 - Bone substitute material with a surface coating of peptides having an rgd amino acid sequence - Google Patents

Bone substitute material with a surface coating of peptides having an rgd amino acid sequence Download PDF

Info

Publication number
WO1998036782A3
WO1998036782A3 PCT/EP1998/000742 EP9800742W WO9836782A3 WO 1998036782 A3 WO1998036782 A3 WO 1998036782A3 EP 9800742 W EP9800742 W EP 9800742W WO 9836782 A3 WO9836782 A3 WO 9836782A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
amino acid
acid sequence
bone substitute
surface coating
Prior art date
Application number
PCT/EP1998/000742
Other languages
German (de)
French (fr)
Other versions
WO1998036782A2 (en
Inventor
Berthold Nies
Original Assignee
Merck Patent Gmbh
Berthold Nies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh, Berthold Nies filed Critical Merck Patent Gmbh
Priority to HU0000900A priority Critical patent/HUP0000900A3/en
Priority to AU61004/98A priority patent/AU6100498A/en
Priority to CA002281608A priority patent/CA2281608A1/en
Priority to EP98905418A priority patent/EP0968010A2/en
Priority to PL98335103A priority patent/PL335103A1/en
Priority to JP53622098A priority patent/JP2001512344A/en
Publication of WO1998036782A2 publication Critical patent/WO1998036782A2/en
Publication of WO1998036782A3 publication Critical patent/WO1998036782A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

The invention relates to a bone substitute material based on a porous polymer material the surface of which is coated with peptides having an RGD amino acid sequence.
PCT/EP1998/000742 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence WO1998036782A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
HU0000900A HUP0000900A3 (en) 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence, use thereof and method for preparation of this material
AU61004/98A AU6100498A (en) 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence
CA002281608A CA2281608A1 (en) 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence
EP98905418A EP0968010A2 (en) 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence
PL98335103A PL335103A1 (en) 1997-02-20 1998-02-11 Bone tissue substitute based on a porous polymeric material having its surface coated with peptides of rgd amino acid sequence
JP53622098A JP2001512344A (en) 1997-02-20 1998-02-11 Bone replacement material having surface coating of peptide having RGD amino acid sequence

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19706667A DE19706667A1 (en) 1997-02-20 1997-02-20 Bone replacement material with a surface covering with peptides with RGD amino acid sequence
DE19706667.4 1997-02-20

Publications (2)

Publication Number Publication Date
WO1998036782A2 WO1998036782A2 (en) 1998-08-27
WO1998036782A3 true WO1998036782A3 (en) 1998-11-19

Family

ID=7820899

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/000742 WO1998036782A2 (en) 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence

Country Status (11)

Country Link
EP (1) EP0968010A2 (en)
JP (1) JP2001512344A (en)
KR (1) KR20000075463A (en)
CN (1) CN1247474A (en)
AU (1) AU6100498A (en)
CA (1) CA2281608A1 (en)
DE (1) DE19706667A1 (en)
HU (1) HUP0000900A3 (en)
PL (1) PL335103A1 (en)
WO (1) WO1998036782A2 (en)
ZA (1) ZA981393B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511496A (en) 1998-04-13 2002-04-16 マサチューセッツ インスティテュート オブ テクノロジー Comb copolymers for modulating cell surface interactions
DE19908318A1 (en) * 1999-02-26 2000-08-31 Michael Hoffmann Hemocompatible surfaces and methods of making them
AU3556400A (en) 1999-03-17 2000-10-04 Novartis Ag Pharmaceutical compositions
DE19950386A1 (en) * 1999-10-19 2001-05-10 Miladin Lazarov Biocompatible item
GB0108767D0 (en) * 2001-04-07 2001-05-30 Univ Leeds Coatings
DE10119096A1 (en) * 2001-04-19 2002-10-24 Keramed Medizintechnik Gmbh New biologically functionalized coatings, useful for e.g. accelerating osteo-integration of implants, e.g. dental or joint implants, comprise resorbable calcium-phosphorus phase containing adhesion and/or signal proteins
KR20040032297A (en) * 2002-10-09 2004-04-17 (주)아미티에 Biodegradable Coating-Implant For Bone Fixation
NL1023602C2 (en) * 2003-06-05 2004-12-07 Univ Eindhoven Tech Process for the preparation of an amino acid-containing solution and the use of such a solution.
KR101013999B1 (en) * 2004-03-19 2011-02-14 재단법인서울대학교산학협력재단 Membrane and implant immobilized osteogenic enhancing peptides on the surface
US8696564B2 (en) 2004-07-09 2014-04-15 Cardiac Pacemakers, Inc. Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth
DE102004043908A1 (en) * 2004-09-10 2006-03-30 GRÄTER, Stefan Surface-structured polymeric substrates and their preparation
FR2876916B1 (en) * 2004-10-25 2007-01-05 Midi Pyrenees Incubateur IMPLANTABLE SURFACE PRODUCT FUNCTIONALIZED BY MEANS OF ANIONIC TERMINAL DENDRIMERS
KR100676945B1 (en) * 2005-03-18 2007-02-01 재단법인서울대학교산학협력재단 Bone graft and scaffolding materials immobilized with osteogenesis enhancing peptides on the surface
DE102006047248B4 (en) 2006-10-06 2012-05-31 Celgen Ag Three-dimensional artificial callus distraction
CN101006944B (en) * 2007-01-31 2010-06-09 浙江大学 A method for assembling RGD on the surface of porous pure titanium dental implant
DE102009042493B4 (en) 2009-09-14 2016-07-21 Celgen3D Ag Granule mixture comprising two different granules for artificial callus distraction
CN102716513B (en) * 2012-05-02 2014-12-24 清华大学 Method for modifying RGD on Ca-P ceramic material surface
US20150224224A1 (en) * 2012-07-14 2015-08-13 Nobel Biocare Services Ag Bioactivated material
GB2503950A (en) * 2012-07-14 2014-01-15 Nobel Biocare Services Ag An agent for promoting osseointegration of bone substitute materials
CN103845759A (en) * 2014-03-14 2014-06-11 国家纳米科学中心 Tissue engineering interface modification material, and modification method and application thereof
CN104474590A (en) * 2014-12-12 2015-04-01 北京博恩康生物科技有限公司 Injectable active bone-repair material and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756862A (en) * 1977-04-14 1988-07-12 Amoco Corporation Prosthetic devices having coatings of selected porous bioengineering thermoplastics
US5330911A (en) * 1989-09-28 1994-07-19 Board Of Regents, The University Of Texas System Surfaces having desirable cell adhesive effects
WO1995019796A1 (en) * 1994-01-21 1995-07-27 Brown University Research Foundation Biocompatible implants

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756862A (en) * 1977-04-14 1988-07-12 Amoco Corporation Prosthetic devices having coatings of selected porous bioengineering thermoplastics
US5330911A (en) * 1989-09-28 1994-07-19 Board Of Regents, The University Of Texas System Surfaces having desirable cell adhesive effects
WO1995019796A1 (en) * 1994-01-21 1995-07-27 Brown University Research Foundation Biocompatible implants

Also Published As

Publication number Publication date
EP0968010A2 (en) 2000-01-05
DE19706667A1 (en) 1998-08-27
WO1998036782A2 (en) 1998-08-27
HUP0000900A2 (en) 2000-10-28
KR20000075463A (en) 2000-12-15
CN1247474A (en) 2000-03-15
ZA981393B (en) 1998-08-24
JP2001512344A (en) 2001-08-21
PL335103A1 (en) 2000-04-10
AU6100498A (en) 1998-09-09
HUP0000900A3 (en) 2000-12-28
CA2281608A1 (en) 1998-08-27

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