WO1998027999A3 - Zusammensetzungen zur behandlung von immunerkrankungen die haptenisierte antigen-antikörper komplexe enthalten - Google Patents

Zusammensetzungen zur behandlung von immunerkrankungen die haptenisierte antigen-antikörper komplexe enthalten Download PDF

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Publication number
WO1998027999A3
WO1998027999A3 PCT/EP1997/007169 EP9707169W WO9827999A3 WO 1998027999 A3 WO1998027999 A3 WO 1998027999A3 EP 9707169 W EP9707169 W EP 9707169W WO 9827999 A3 WO9827999 A3 WO 9827999A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
antibody complexes
antigen antibody
immune diseases
diseases containing
Prior art date
Application number
PCT/EP1997/007169
Other languages
English (en)
French (fr)
Other versions
WO1998027999A2 (de
Inventor
Hilmar Lemke
Uta Opitz
Original Assignee
Hilmar Lemke
Uta Opitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP96120822A external-priority patent/EP0853946A1/de
Application filed by Hilmar Lemke, Uta Opitz filed Critical Hilmar Lemke
Priority to AU60905/98A priority Critical patent/AU6090598A/en
Priority to EP97954930A priority patent/EP0952848A2/de
Priority to DE19781463T priority patent/DE19781463D2/de
Publication of WO1998027999A2 publication Critical patent/WO1998027999A2/de
Publication of WO1998027999A3 publication Critical patent/WO1998027999A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6056—Antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Die Erfindung betrifft Antigen-Antikörper-Komplexe, die bei der Prophylaxe und Therapie von allergenen Erkrankungen eingesetzt werden. Die Antigene sind haptenisiert und die Antikörper sind gegen das entsprechende Hapten gerichtet.
PCT/EP1997/007169 1996-12-23 1997-12-19 Zusammensetzungen zur behandlung von immunerkrankungen die haptenisierte antigen-antikörper komplexe enthalten WO1998027999A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU60905/98A AU6090598A (en) 1996-12-23 1997-12-19 Anti-allergenic compound
EP97954930A EP0952848A2 (de) 1996-12-23 1997-12-19 Anti-allergene zusammensetzung
DE19781463T DE19781463D2 (de) 1996-12-23 1997-12-19 Anti-allergene Zusammensetzung

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP96120822A EP0853946A1 (de) 1996-12-23 1996-12-23 Anti-Allergene Zusammensetzung
EP96120822.0 1996-12-23
EP97115435 1997-09-06
EP97115435.6 1997-09-06

Publications (2)

Publication Number Publication Date
WO1998027999A2 WO1998027999A2 (de) 1998-07-02
WO1998027999A3 true WO1998027999A3 (de) 1998-10-29

Family

ID=26142410

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1997/007169 WO1998027999A2 (de) 1996-12-23 1997-12-19 Zusammensetzungen zur behandlung von immunerkrankungen die haptenisierte antigen-antikörper komplexe enthalten

Country Status (4)

Country Link
EP (1) EP0952848A2 (de)
AU (1) AU6090598A (de)
DE (1) DE19781463D2 (de)
WO (1) WO1998027999A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001039799A2 (en) * 1999-12-06 2001-06-07 Panacea Pharmaceuticals, Llc. Passive desensitization
AU2002318045A1 (en) * 2002-07-01 2004-01-19 Ramon Suarez Mendoza Method of transforming autoimmune-disease-causing hapten-antigens (hapigens) of an organism into complete antigens
EP1845970B1 (de) * 2005-01-31 2013-08-28 Cephalon, Inc. Hemmer von tumornekrose-faktoren

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415552A (en) * 1979-02-06 1983-11-15 The Governors Of The University Of Alberta Composition for establishing immunological tolerance
EP0287361A2 (de) * 1987-04-16 1988-10-19 International Institute Of Cellular And Molecular Pathology (Icp) Allergiebehandlung und Zusammensetzung dafür
WO1992004033A1 (en) * 1990-08-30 1992-03-19 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415552A (en) * 1979-02-06 1983-11-15 The Governors Of The University Of Alberta Composition for establishing immunological tolerance
EP0287361A2 (de) * 1987-04-16 1988-10-19 International Institute Of Cellular And Molecular Pathology (Icp) Allergiebehandlung und Zusammensetzung dafür
WO1992004033A1 (en) * 1990-08-30 1992-03-19 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; NEVEU P. J. ET AL: "MODULATION OF THE IMMUNE RESPONSE BY PASSIVE ANTIBODIES. II. EFFECTS OF PASSIVE ANTI - HAPTEN AND ANTI - CARRIER ANTIBODIES ON THE IMMUNE RESPONSE TO A SUSTAINED ANTIGENIC STIMULATION", XP002031002 *
INT. ARCH. ALLERGY APPL. IMMUNOL. (1975), vol. 51, no. 2, 1975, pages 238 - 244 *

Also Published As

Publication number Publication date
AU6090598A (en) 1998-07-17
WO1998027999A2 (de) 1998-07-02
DE19781463D2 (de) 2000-03-16
EP0952848A2 (de) 1999-11-03

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