WO1998007821A1 - Detergent compositions comprising antibody controlled cellulolytic activity - Google Patents
Detergent compositions comprising antibody controlled cellulolytic activity Download PDFInfo
- Publication number
- WO1998007821A1 WO1998007821A1 PCT/US1996/013370 US9613370W WO9807821A1 WO 1998007821 A1 WO1998007821 A1 WO 1998007821A1 US 9613370 W US9613370 W US 9613370W WO 9807821 A1 WO9807821 A1 WO 9807821A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cellulase
- detergent
- alkyl
- antibody
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/384—Animal products
- C11D3/3845—Antibodies
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38645—Preparations containing enzymes, e.g. protease or amylase containing cellulase
Definitions
- the present invention relates to laundry detergent compositions comprising a cellulase-directed antibody and a cellulase in order to prevent potential tensile strength loss related to the hydrolytic activity of cellulase on cellulose substrates while maintaining the desired benefits from the use of cellulase.
- Heavy and light chains are indeed composed of constant and variable domains.
- the constant domains are very important for a number of functions, but for many applications in industrial processes and products their variable domains are sufficient. Consequently many methods have been described to produce antibody fragments.
- the antibodies and release agents can be contained in a granulate.
- Said antibody granulate can suitably contain various granulation aids, binders, fillers, plasticizers, lubricants, cores and the like.
- granulation aids include cellulose (e.g. cellulosic fibers or in microcrystalline form) , cellulose derivatives (CMC, MC, HPC, HPMC) , gelatin, starch, dextrins, sugars, polyvinylpyrrolidone, PVA, PEG, salts (e.g. sodium sulfate, calcium sulfate) , titanium dioxide, talc, clays (kaolin or bentonite) and nonionic surfactants.
- Other materials of relevance for incorporation in the granulate are described in EP 304 331.
- the cellulases having a non-degrading index (NDI) of not less than 500 and being alkalophilic cellulases having an optimum pH not less than 7 or whose relative activity at a pH of not less than 8 is 50% or over of the activity under optimum conditions when carboxy methyl cellulose (CMC) is used as a substrate, or an endoglucanase component which is immunoreactive with an antibody raised against a highly purified ⁇ 43kD endoglucanase derived from Humicola insolens, DSM 1800, or which is a homologue or derivative of the ⁇ 43kD endoglucanase exhibiting cellulase activity; a preferred endoglucanase component has the amino acid sequence disclosed in PCT Patent Application No.
- y is 2-4, preferably 3. whereby R2 is H or a C1-C3 alkyl, whereby x is 0-4, preferably 0-2, most preferably 0, whereby R3 , R4 and R5 are either the same or different and can be either a short chain alkyl (C1-C3) or alkoxylated alkyl of the formula III,
- R2R3 and R4 are methyl and hydroxyethyl groups and the anion X may be selected from halide, methosulphate , acetate and phosphate ions.
- suitable quaternary ammonium compounds of formulae (i) for use herein are : coconut trimethyl ammonium chloride or bromide; coconut methyl dihydroxyethyl ammonium chloride or bromide ; decyl triethyl ammonium chloride; decyl dimethyl hydroxyethyl ammonium chloride or bromide;
- Preferred amines according to the formula herein above are n-alkyl amines. Suitable amines for use herein may be selected from 1-hexylamine, 1-octylamine, 1-decylamine and laurylamine . Other preferred primary amines include C8-C10 oxypropylamine , octyloxypropylamine, 2 -ethylhexyl- oxypropylamine, lauryl amido propylamine and amido propylamine .
- Preferred tertiary amines are R1R2R3N where Rl is a C6-C12 alkyl chain, R2 and R3 are C1-C3 alkyl or
- the most preferred amines for use in the compositions herein are 1-hexylamine, 1-octylamine, 1-decylamine, 1- dodecylamine .
- Especially desirable are n- dodecyldimethylamine and bishydroxyethylcoconutalkylamine and oleylamine 7 times ethoxylated, lauryl amido propylamine and cocoamido propylamine .
- amylases include Purafact Ox Am R described in WO 94/18314, published August 18, 1994; WO96/05295, Genencor, published February 22, 1995 and amylase variants having additional modification in the immediate parent available from Novo Nordisk A/S, disclosed in WO 95/10603, published April 95.
- Preferred builder systems include a mixture of a water- insoluble aluminosilicate builder such as zeolite A, and a watersoluble carboxylate chelating agent such as citric acid.
- compositions can comprise a silicone/silica mixture in combination with fumed nonporous silica such as Aerosil R .
- polyethylene glycols particularly those of molecular weight 1000-10000, more particularly 2000 to 8000 and most preferably about 4000. These are used at levels of from 0.20% to 5% more preferably from 0.25% to 2.5% by weight. These polymers and the previously mentioned homo- or co-polymeric polycarboxylate salts are valuable for improving whiteness maintenance, fabric ash deposition, and cleaning performance on clay, proteinaceous and oxidizable soils in the presence of transition metal impurities.
- modified polyesters as random copolymers of dimethyl terephthalate, dimethyl sulfoisophthalate, ethylene glycol and 1-2 propane diol, the end groups consisting primarily of sulphobenzoate and secondarily of mono esters of ethylene glycol and/or propane-diol .
- the target is to obtain a polymer capped at both end by sulphobenzoate groups, "primarily", in the present context most of said copolymers herein will be end- capped by sulphobenzoate groups.
- Alkoxylated polycarboxylates such as those prepared from polyacrylates are useful herein to provide additional grease removal performance. Such materials are described in WO 91/08281 and PCT 90/01815 at p. 4 et seq. , incorporated herein by reference. Chemically, these materials comprise polyacrylates having one ethoxy side- chain per every 7-8 acrylate units.
- the side-chains are of the formula - (CH2CH2O) m (CH2) n CH 3 wherein m is 2-3 and n is 6-12.
- the side-chains are ester- linked to the polyacrylate "backbone” to provide a "comb" polymer type structure.
- the molecular weight can vary, but is typically in the range of about 2000 to about 50,000.
- Levels of smectite clay are normally in the range from 2% to 20%, more preferably from 5% to 15% by weight, with the material being added as a dry mixed component to the remainder of the formulation.
- Organic fabric softening agents such as the water-insoluble tertiary amines or dilong chain amide materials are incorporated at levels of from 0.5% to 5% by weight, normally from 1% to 3% by weight whilst the high molecular weight polyethylene oxide materials and the water soluble cationic materials are added at levels of from 0.1% to 2%, normally from 0.15% to 1.5% by weight.
- These materials are normally added to the spray dried portion of the composition, although in some instances it may be more convenient to add them as a dry mixed particulate, or spray them as molten liquid on to other solid components of the composition.
- the detergent composition of the present invention can also contain dispersants : Suitable water-soluble organic salts are the homo- or co-polymeric acids or their salts, in which the polycarboxylic acid comprises at least two carboxyl radicals separated from each other by not more than two carbon atoms .
- copolymer of acrylate and methylacrylate such as the 480N having a molecular weight of 4000, at a level from 0.5-20% by weight of composition can be added in the detergent compositions of the present invention.
- R wherein P is a polymerisable unit, whereto the R-N-0 group can be attached to or wherein the R-N-0 group forms part of the polymerisable unit or a combination of both.
- Silicone Polydimethylsiloxane foam controller antifoam with siloxane-oxyalkylene copolymer as dispersing agent with a ratio of said foam controller to said dispersing agent Of 10 :1 to 100:1.
- the Carezyme solution was diluted in the Tris buffer to a final concentration of 0.6 CEVU/ml .
- the carezyme preparation was incubated with the antibody solution (0.18 mg/ml) during 60 minutes at 30°C, 40°C and 50°C.
- the detergent solution already contained Carezyme at an initial level of 0.6 CEVU/ml and the antibody was subsequently thereto added.
- laundry detergent compositions were prepared in accord with the invention:
- Brightener 1 0.08 0.19 0.19 Brightener 2 0.04 0.04 Encapsulated perfume 0.3 0.3 0.3 particles Silicone antifoam 0.5 2.4 2.4 Minors/misc to 100%
- Syndet bar fabric cleaning compositions were prepared in accord with the present invention :
- Detergent additives were prepared in accord with the present invention :
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Detergent Compositions (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU69537/96A AU6953796A (en) | 1996-08-16 | 1996-08-16 | Detergent compositions comprising antibody controlled cellulolytic activity |
PCT/US1996/013370 WO1998007821A1 (en) | 1996-08-16 | 1996-08-16 | Detergent compositions comprising antibody controlled cellulolytic activity |
CN97198595.2A CN1232492A (zh) | 1996-08-16 | 1997-08-13 | 含有抗体的控制纤维素活性的洗涤剂组合物 |
PCT/US1997/011544 WO1998007823A1 (en) | 1996-08-16 | 1997-08-13 | Detergent compositions comprising antibody controlled cellulolytic activity |
BR9711626-2A BR9711626A (pt) | 1996-08-16 | 1997-08-13 | "composições detergentes compreendendo atividade celulolìtica controlada por anticorpo" |
CA002263430A CA2263430A1 (en) | 1996-08-16 | 1997-08-13 | Detergent compositions comprising antibody controlled cellulolytic activity |
JP10510727A JP2000500818A (ja) | 1996-08-16 | 1997-08-13 | 抗体で制御されるセルロース分解活性を有する洗剤組成物 |
EP97936031A EP0918839A1 (en) | 1996-08-16 | 1997-08-13 | Detergent compositions comprising antibody controlled cellulolytic activity |
ARP970103732A AR009261A1 (es) | 1996-08-16 | 1997-08-15 | Composicion detergente que comprende una celulasa y un anticuerpo direccional contra la celulasa, aditivo detergente y su uso para controlarla actividad celulitico-enzimatica |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1996/013370 WO1998007821A1 (en) | 1996-08-16 | 1996-08-16 | Detergent compositions comprising antibody controlled cellulolytic activity |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998007821A1 true WO1998007821A1 (en) | 1998-02-26 |
Family
ID=22255632
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1996/013370 WO1998007821A1 (en) | 1996-08-16 | 1996-08-16 | Detergent compositions comprising antibody controlled cellulolytic activity |
PCT/US1997/011544 WO1998007823A1 (en) | 1996-08-16 | 1997-08-13 | Detergent compositions comprising antibody controlled cellulolytic activity |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/011544 WO1998007823A1 (en) | 1996-08-16 | 1997-08-13 | Detergent compositions comprising antibody controlled cellulolytic activity |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0918839A1 (pt) |
JP (1) | JP2000500818A (pt) |
CN (1) | CN1232492A (pt) |
AR (1) | AR009261A1 (pt) |
AU (1) | AU6953796A (pt) |
BR (1) | BR9711626A (pt) |
CA (1) | CA2263430A1 (pt) |
WO (2) | WO1998007821A1 (pt) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000066696A1 (en) * | 1999-04-29 | 2000-11-09 | Genencor International, Inc. | Cellulase detergent matrix |
WO2001036577A1 (en) * | 1999-11-16 | 2001-05-25 | Unilever N.V. | Process for rinsing fabrics |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102010063457A1 (de) * | 2010-12-17 | 2012-06-21 | Henkel Ag & Co. Kgaa | Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Protease und Cellulase |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0298654A2 (en) * | 1987-07-07 | 1989-01-11 | Hybrisens Ltd. | Use of antibody/antigen interactions to protect or modulate biological activity |
WO1991006574A1 (en) * | 1989-11-02 | 1991-05-16 | Novo Nordisk A/S | A process for preparing peroxycarboxylic acids |
WO1991017243A1 (en) * | 1990-05-09 | 1991-11-14 | Novo Nordisk A/S | A cellulase preparation comprising an endoglucanase enzyme |
WO1994007998A1 (en) * | 1992-10-06 | 1994-04-14 | Novo Nordisk A/S | Cellulase variants |
WO1994021801A2 (en) * | 1993-03-17 | 1994-09-29 | Genencor International, Inc. | Purification and molecular cloning of eg iii cellulase |
WO1995024471A1 (en) * | 1994-03-08 | 1995-09-14 | Novo Nordisk A/S | Novel alkaline cellulases |
-
1996
- 1996-08-16 WO PCT/US1996/013370 patent/WO1998007821A1/en active Application Filing
- 1996-08-16 AU AU69537/96A patent/AU6953796A/en not_active Abandoned
-
1997
- 1997-08-13 EP EP97936031A patent/EP0918839A1/en not_active Withdrawn
- 1997-08-13 BR BR9711626-2A patent/BR9711626A/pt not_active Application Discontinuation
- 1997-08-13 JP JP10510727A patent/JP2000500818A/ja active Pending
- 1997-08-13 CN CN97198595.2A patent/CN1232492A/zh active Pending
- 1997-08-13 WO PCT/US1997/011544 patent/WO1998007823A1/en not_active Application Discontinuation
- 1997-08-13 CA CA002263430A patent/CA2263430A1/en not_active Abandoned
- 1997-08-15 AR ARP970103732A patent/AR009261A1/es unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0298654A2 (en) * | 1987-07-07 | 1989-01-11 | Hybrisens Ltd. | Use of antibody/antigen interactions to protect or modulate biological activity |
WO1991006574A1 (en) * | 1989-11-02 | 1991-05-16 | Novo Nordisk A/S | A process for preparing peroxycarboxylic acids |
WO1991017243A1 (en) * | 1990-05-09 | 1991-11-14 | Novo Nordisk A/S | A cellulase preparation comprising an endoglucanase enzyme |
WO1994007998A1 (en) * | 1992-10-06 | 1994-04-14 | Novo Nordisk A/S | Cellulase variants |
WO1994021801A2 (en) * | 1993-03-17 | 1994-09-29 | Genencor International, Inc. | Purification and molecular cloning of eg iii cellulase |
WO1995024471A1 (en) * | 1994-03-08 | 1995-09-14 | Novo Nordisk A/S | Novel alkaline cellulases |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000066696A1 (en) * | 1999-04-29 | 2000-11-09 | Genencor International, Inc. | Cellulase detergent matrix |
US6565613B1 (en) | 1999-04-29 | 2003-05-20 | Genencor International, Inc. | Cellulase detergent matrix |
WO2001036577A1 (en) * | 1999-11-16 | 2001-05-25 | Unilever N.V. | Process for rinsing fabrics |
Also Published As
Publication number | Publication date |
---|---|
CA2263430A1 (en) | 1998-02-26 |
EP0918839A1 (en) | 1999-06-02 |
JP2000500818A (ja) | 2000-01-25 |
CN1232492A (zh) | 1999-10-20 |
AU6953796A (en) | 1998-03-06 |
BR9711626A (pt) | 2000-10-17 |
WO1998007823A1 (en) | 1998-02-26 |
AR009261A1 (es) | 2000-04-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1998006806A1 (en) | Detergent compositions comprising a pectinesterase enzyme | |
CA2282352A1 (en) | Cleaning compositions comprising xylan degrading alkaline enzyme and non-plant cell walls degrading enzyme | |
CA2263536A1 (en) | Detergent compositions comprising alkaline pectin degrading enzyme | |
CA2294925A1 (en) | Enzymatic detergent compositions | |
CA2261754A1 (en) | Detergent compositions comprising improved amylase for dingy fabric clean-up | |
WO1998007817A1 (en) | Detergent compositions comprising antibody controlled lipolytic activity | |
WO1998006812A1 (en) | Detergent compositions comprising antibody controlled enzymatic activity | |
WO1998006809A1 (en) | Detergent compositions comprising alkaline polygalacturonase | |
WO1998007821A1 (en) | Detergent compositions comprising antibody controlled cellulolytic activity | |
EP1073726A1 (en) | Laundry detergent and/or fabric care compositions comprising a modified cellulase | |
WO1998007816A1 (en) | Detergent compositions comprising oxido-reductase antibody | |
WO1998007818A1 (en) | Detergent compositions comprising antibody controlled amylolytic activity | |
WO1998006807A1 (en) | Detergent compositions comprising pectin lyase | |
WO1998006805A1 (en) | Detergent compositions comprising pectolyase | |
WO1998007819A1 (en) | Detergent compositions comprising antibody controlled proteolytic activity | |
WO1999057257A1 (en) | Laundry detergent and/or fabric care compositions comprising a modified cellulase | |
CA2267286A1 (en) | Cleaning compositions comprising a mycodextranase | |
MXPA99001625A (en) | Detergent compositions comprising antibody controlled cellulolytic activity | |
MXPA99001622A (en) | Detergent compositions comprising antibody controlled amylolytic activity | |
MXPA99001620A (en) | Detergent compositions comprising antibody controlled proteolytic activity | |
MXPA99001621A (en) | Detergent compositions comprising antibody controlled lipolytic activity |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AL AM AT AU AZ BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE HU IL IS JP KE KG KP KR KZ LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG US UZ VN AM AZ BY KG KZ MD RU TJ TM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
NENP | Non-entry into the national phase |
Ref country code: JP Ref document number: 98510681 Format of ref document f/p: F |
|
NENP | Non-entry into the national phase |
Ref country code: CA |
|
122 | Ep: pct application non-entry in european phase |