WO1997029194A3 - Herstellung von l-ascorbinsäure - Google Patents

Herstellung von l-ascorbinsäure Download PDF

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Publication number
WO1997029194A3
WO1997029194A3 PCT/EP1997/000461 EP9700461W WO9729194A3 WO 1997029194 A3 WO1997029194 A3 WO 1997029194A3 EP 9700461 W EP9700461 W EP 9700461W WO 9729194 A3 WO9729194 A3 WO 9729194A3
Authority
WO
WIPO (PCT)
Prior art keywords
ascorbic acid
preparation
enzymes
codes
synthesis
Prior art date
Application number
PCT/EP1997/000461
Other languages
English (en)
French (fr)
Other versions
WO1997029194A2 (de
Inventor
Ralf Mattes
Heidrun Schmidt
Klaus-Dieter Kulbe
Gernot Miemietz
Original Assignee
Herbstreith & Fox Kg Pektin Fa
Ralf Mattes
Heidrun Schmidt
Kulbe Klaus Dieter
Gernot Miemietz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Herbstreith & Fox Kg Pektin Fa, Ralf Mattes, Heidrun Schmidt, Kulbe Klaus Dieter, Gernot Miemietz filed Critical Herbstreith & Fox Kg Pektin Fa
Priority to EP97901626A priority Critical patent/EP0879287A2/de
Publication of WO1997029194A2 publication Critical patent/WO1997029194A2/de
Publication of WO1997029194A3 publication Critical patent/WO1997029194A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C

Abstract

Die Erfindung betrifft ein neues Verfahren zur Synthese von L-Ascorbinsäure, für dieses Verfahren geeignete rekombinante Enzyme und die für die Enzyme kodierende Nucleinsäure.
PCT/EP1997/000461 1996-02-09 1997-02-03 Herstellung von l-ascorbinsäure WO1997029194A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP97901626A EP0879287A2 (de) 1996-02-09 1997-02-03 Herstellung von l-ascorbinsäure

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19604798.6 1996-02-09
DE19604798A DE19604798A1 (de) 1996-02-09 1996-02-09 Herstellung von L-Ascorbinsäure

Publications (2)

Publication Number Publication Date
WO1997029194A2 WO1997029194A2 (de) 1997-08-14
WO1997029194A3 true WO1997029194A3 (de) 1997-10-02

Family

ID=7784990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1997/000461 WO1997029194A2 (de) 1996-02-09 1997-02-03 Herstellung von l-ascorbinsäure

Country Status (3)

Country Link
EP (1) EP0879287A2 (de)
DE (1) DE19604798A1 (de)
WO (1) WO1997029194A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105671106B (zh) * 2016-02-16 2021-06-11 珀莱雅化妆品股份有限公司 一种采用橄榄油发酵法制备鞘糖脂的方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1026257B1 (de) * 1999-01-18 2006-04-12 DSM IP Assets B.V. Herstellung von L-Ascorbinsäure und D-Erythorbinsäure
ATE323172T1 (de) * 1999-01-18 2006-04-15 Dsm Ip Assets Bv Herstellung von l-ascorbinsäure und d- erythorbinsäure
FI20055263A0 (fi) * 2005-05-30 2005-05-30 Valtion Teknillinen Sokerihappojen mikrobinen muuttaminen ja siihen soveltuvia välineitä
EP2274417B1 (de) * 2008-04-04 2013-07-24 Massachusetts Institute of Technology Zelluläre herstellung von glucarinsäure
JP2013541942A (ja) * 2010-10-08 2013-11-21 カディラ ヘルスケア リミティド 酵素的変換によるシタグリプチンの中間体を生産する方法
US11384135B2 (en) * 2017-09-22 2022-07-12 Modern Meadow, Inc. Recombinant yeast strains

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986004353A1 (en) * 1985-01-23 1986-07-31 Fraunhofer-Gesellschaft Zur Förderung Der Angewand Process for the intrasequential cofactor regeneration in enzymatic synthesis, particularly when producing vitamine c
JPH0191785A (ja) * 1987-10-02 1989-04-11 Bitamin Kenkyusho:Kk Ｌ―グロノラクトン酸化酵素のクローン化ｄｎａ、該クローン化ｄｎａの組込まれた遺伝子組換えベクター及び該ベクターにより形質転換された宿主細胞
WO1997004100A2 (de) * 1995-07-17 1997-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. L-galactonatoxidoreduktase-ascorbinsäuresynthese

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986004353A1 (en) * 1985-01-23 1986-07-31 Fraunhofer-Gesellschaft Zur Förderung Der Angewand Process for the intrasequential cofactor regeneration in enzymatic synthesis, particularly when producing vitamine c
JPH0191785A (ja) * 1987-10-02 1989-04-11 Bitamin Kenkyusho:Kk Ｌ―グロノラクトン酸化酵素のクローン化ｄｎａ、該クローン化ｄｎａの組込まれた遺伝子組換えベクター及び該ベクターにより形質転換された宿主細胞
WO1997004100A2 (de) * 1995-07-17 1997-02-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. L-galactonatoxidoreduktase-ascorbinsäuresynthese

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 8920, Derwent World Patents Index; Class B04, AN 89-148142, XP002029312 *
EMBL Datenbank Eingabe SCREDUC 'Accession' Nummer X80642; 04 Dez 1995 MIOSGA T ET AL.:'A new yeast gene with homology to the aldo-keto reductase protein family' *
GENESEQ Datenbank Eingabe mit 'Accession' Nummer N92440: 30 Apr 1990 *
GENESEQ Datenbank Eingabe mit 'Accession' Nummer P91897: 30 Apr 1990 *
HALLER C -P ET AL: "ENZYMATIC SYNTHESIS OF L-ASCORBIC ACID 3. L-GALACTONO-GAMMA-LACTONE OXIDASE FROM YEASTS", DECHEMA BIOTECHNOLOGY CONFERENCE, vol. 4, 1990, pages 233 - 236, XP000646759 *
KULBE KD ET AL: "Enzymatic synthesis of L-ascorbic acid via D-uronic acids;membrane-reactor integrated recovery of D-galacturonic acid from pectin hydrolysates.", ANN N Y ACAD SCI, 1987, 506 P543-51, UNITED STATES, XP000646778 *
OECHSNER U ET AL.: "A nuclear yeast gene (CCY) encodes a polypeptide with high homology to a vertebrate eye lens protein", FEBS LETTERS, vol. 238, no. 1, 1988, AMSTERDAM NL, pages 123 - 128, XP000647862 *
PIR Datenbank Eingabe 'Accession' Nummer S61163; 23 Feb 1996 MIOSGA T ET AL.:'A new yeast gene with homology to the aldo-deto reductase protein family' *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105671106B (zh) * 2016-02-16 2021-06-11 珀莱雅化妆品股份有限公司 一种采用橄榄油发酵法制备鞘糖脂的方法

Also Published As

Publication number Publication date
WO1997029194A2 (de) 1997-08-14
DE19604798A1 (de) 1997-08-14
EP0879287A2 (de) 1998-11-25

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