WO1997024154A1 - Multipurpose balloon catheter - Google Patents

Multipurpose balloon catheter Download PDF

Info

Publication number
WO1997024154A1
WO1997024154A1 PCT/US1996/020903 US9620903W WO9724154A1 WO 1997024154 A1 WO1997024154 A1 WO 1997024154A1 US 9620903 W US9620903 W US 9620903W WO 9724154 A1 WO9724154 A1 WO 9724154A1
Authority
WO
WIPO (PCT)
Prior art keywords
balloon
proximal
tubular body
distal
end portion
Prior art date
Application number
PCT/US1996/020903
Other languages
French (fr)
Inventor
James Ernest Leone
Karl Phillip Weissinger
Margaret Frances Yoklavich
Original Assignee
Cordis Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cordis Corporation filed Critical Cordis Corporation
Priority to EP96945449A priority Critical patent/EP0935479B1/en
Priority to DE69633410T priority patent/DE69633410T2/en
Priority to CA002241176A priority patent/CA2241176C/en
Publication of WO1997024154A1 publication Critical patent/WO1997024154A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958Inflatable balloons for placing stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1011Multiple balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/105Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1052Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1065Balloon catheters with special features or adapted for special applications having a balloon which is inversely attached to the shaft at the distal or proximal end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes

Definitions

  • the present invention relates to a multi-purpose balloon catheter having an angioplasty, occlusive/drug delivery or photodynamic therapy (PDT) balloon, a stent delivery balloon or iontophoresis section, and an occlusive/drug delivery balloon in a distal end portion ofthe catheter.
  • the multi-purpose balloon catheter ofthe present invention includes two or more lumens therein extending to the distal end portion ofthe multi-purpose balloon catheter.
  • a multi-purpose balloon catheter comprising a tubular body having a proximal end portion, a distal end portion and at least two lumens within the tubular body, and the distal end portion having three spaced apart balloons thereon, the distal balloon being an occlusive balloon, the middle balloon being a stent mounting balloon and the proximal balloon being an occlusive balloon.
  • the distal balloon is an angioplasty balloon and the proximal balloon is also a drug therapy balloon.
  • FIG. 1 is a plan view of the multi-purpose balloon catheter constructed according to the teachings ofthe present invention and shows a distal end portion ofthe catheter and a proximal end portion of the catheter.
  • FIG. 2 is an enlarged view of the distal end portion of the catheter shown in FIG. 1 and shows a first angioplasty balloon, a second or middle stent mounting balloon and a third, occlusive/drug delivery balloon.
  • FIG. 3 is a sectional view taken along lines 3-3 of FIG. 2.
  • FIG. 4 is a sectional view taken along lines 4-4 of FIG. 1.
  • FIG. 5 is an enlarged cross-sectional view ofthe occlusive/drug delivery balloon shown in
  • FIG. 6 is a longitudinal view with portions cut away ofa section ofa blood vessel and shows the distal end portion of the multi-purpose balloon catheter of the present invention disposed therein and with the first, most distal, balloon thereof in an inflated condition.
  • FIG. 7 is a longitudinal view ofthe blood vessel shown in FIG. 6 with portions cut away and shows the distal end portion of the multi-purpose balloon catheter therein, similar to the view shown in FIG. 5, but with a proximally located third, occlusive/drug delivery balloon also inflated.
  • FIG. 8 is a longitudinal view ofthe blood vessel shown in FIG. 6 with portions cut away and shows the distal end portion of the multi-purpose balloon catheter of the present invention disposed therein but with the angioplasty balloon and the thrombolysis balloon collapsed and with a stent mounting (delivery) balloon disposed between them inflated for the purpose of stent implantation.
  • FIG. 9 is a longitudinal view ofthe blood vessel shown in FIG. 6 with portions cut away and shows the distal end portion of the multi-purpose balloon catheter of the present invention disposed therein, similar to the view shown in FIG. 6, but shows an aneurysm in the portion ofthe blood vessel between the first, angioplasty balloon and the third occlusive/drug delivery balloon. DESCRIPTION OF THE PREFERRED EMBODIMENT(S)
  • the distal end portion 16 includes a first, most distal, occlusive/angioplasty/photodynamic balloon 20, a second, or middle stent mounting or stent delivery balloon 22 capable of carrying a stent 24 thereon, which can be a metal stent or a thermoplastic stent, and a third, occlusive/drug delivery balloon 26.
  • the tip 18 has a distal ring electrode 30 which is electrically coupled with a distal ring electrode 32 located just proximally ofthe occlusive balloon 26.
  • Proximal of the ring electrode 32 are one or more, namely four, perfusion ports 34.
  • the distal tip 18 is open at the outer end thereof to form a perfusion port 36 which is in communication with a perfusion lumen 38 within the tubular body 14 in the distal end portion 16 which is also in communication with the perfusion ports 34.
  • the proximal end portion 12 includes four input tubings 41-44 connected to a coupling member 46 that couples through a strain relief sleeve 48 to the tubular body 14.
  • an electrical cable 50 having at least two insulated wire conductors 51 and 52 that extend through the tubular body to the electrodes 30, 32 and the stent 24. Wire conductor 51 connects to the ring electrodes 30 and 32 and wire conductor 52 connects to the stent 24.
  • FIG. 3 is a sectional view through the tubular body 14, is taken along lines 3-3 of FIG. 2 and shows the perfusion lumen 38, which is the largest lumen, a fluid delivery lumen 54 for the stent mounting balloon 22 directly above the perfusion lumen 38, a fluid delivery lumen 56 for the angioplasty balloon 20 which also can have a light delivery fiber 57 therein, and a fluid delivery lumen 58 for delivering a fluid and/or drug to the occlusive/drug delivery balloon 26.
  • FIG. 4 is a sectional view ofthe tubings 41-44 shown in FIG. 1 and is taken along line 4-4 of FIG. 1.
  • the multi-purpose balloon catheter 10 ofthe present invention can be utilized for performing a number of procedures which will now be described in greater detail in connection with the description of FIGS. 5-9.
  • the occlusive/drug balloon 26 has a proximal end 60 fixed on the tubular body just proximal to a fluid delivery inlet port 62.
  • the balloon 26 has a distal end portion 64 which is inverted, or folded under itself, over the tubular body 14 and connected thereto as shown.
  • two or more outlet ports 66 are provided in an inwardly facing section 67 ofthe distal end portion 64 ofthe balloon 26.
  • FIG. 5 The balloon construction for the third balloon 26 illustrated in FIG. 5 is preferred when the third balloon 26 is used for drug delivery and can be used with a saline solution for other procedures illustrated in FIGS. 7 and 9. However, for these procedures it is desirable to use a balloon not having the outlet ports 66.
  • FIG. 6 there is illustrated the distal end portion 16 ofthe multi-purpose balloon catheter
  • the angioplasty balloon 20 can be made of a transparent or translucent plastic material and light can be supplied through the light delivery fiber 57 and directed through the transparent or translucent balloon 20 for photodynamic therapy.
  • FIG. 7 there is illustrated an iontophoresis procedure which can include drug delivery or thrombolysis.
  • the first balloon 20 is only inflated sufficient to occlude the blood vessel 70 and the third, occlusive balloon 26 is supplied with a drug solution from the lumen 58 and the inlet port 62 which is used for both inflating the balloon 26 from the lumen 58 through the inlet port 62 and for delivering a drug solution through the outlet port 66 ofthe balloon 26 to the area in the blood vessel 70 between the first balloon 20 and the third balloon 26.
  • the stent 24 can be used as an electrode and for this purpose covered with a porous polycarbonate membrane 72, a fragmentary portion of which is shown in FIG. 7. This covering will prevent shorting ofthe stent electrode 24 to the inner wall ofthe blood vessel 70.
  • the iontophoresis electrical circuit is completed through a silver oxide (+) or silver (-) electrodes 30, 32 depending on the polarity needed.
  • the first balloon 20 can be an inversion of the drug delivery balloon 26 and can be constructed in the same manner but as a mirror image ofthe balloon 26 shown in FIG. 5 whereby drug delivery is supplied through both the first and third balloons 20 and 26 which serve as occlusive and drug delivery balloons for this procedure.
  • FIG. 8 there is illustrated a stent implantation procedure where only the middle, second, stent delivery balloon 22 is inflated for implanting the stent 24.
  • the stent 24 can be a drug delivery stent ofthe type disclosed in U.S. Patent Application Serial No. 08/304,163 filed on September 12, 1994 and entitled: RETRIEVABLE DRUG DELIVERY STENT, the disclosure of which is incorporated herein by reference.
  • a stent sheath for local drug delivery is disclosed in U.S. Patent No. 5,383,928.
  • the stent 24 can be implanted and, if desired, utilized for delivery of a drug through the stent to the inner wall ofthe blood vessel 70.
  • FIG. 9 there is illustrated the use ofthe multi-purpose balloon catheter 10 as a "bail-out catheter" where the first and third balloons are positioned on either side of an aneurysm or thrombosis and inflated to bridge the aneurysm.
  • the multi-purpose balloon catheter 10 is illustrated as a "bail-out catheter" where the first and third balloons are positioned on either side of an aneurysm or thrombosis and inflated to bridge the aneurysm.
  • the third balloon 26 can be used to deliver a lysing agent 76 or other substance through the outlet ports 66 to the area of the aneurysm.
  • blood can flow through the perfusion ports 34, then through the perfusion lumen 38 and out the perfusion outlet port 36 to maintain blood flow while the aneurysm 74 is being treated.
  • a stent 24 can be omitted from the second balloon 22 when performing the procedures shown in FIGS. 6 and 9.
  • the balloon 26 can be constructed without outlet ports 66.
  • the first balloon 20 can have a mirror image construction ofthe balloon 26 (inverted from the construction shown in FIG. 5).

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The multipurpose balloon catheter (10) comprises a tubular body (14) having a proximal end portion (12), a distal end portion (16), and at least two lumens within the tubular body (14). The distal end portion (16) has three spaced-apart balloons thereon, the distal balloon (20) being an occlusive balloon, the middle balloon (22) being a stent mounting balloon, and the proximal balloon (26) being an occlusive balloon.

Description

MULTI-PURPOSE BALLOON CATHETER BACKGROUND OF INVENTION
This is a continuation-in-part of patent application Serial No. 08/259,534, filed on June 14, 1994, now Patent No. 5,505,700. 1. Field of the Invention.
The present invention relates to a multi-purpose balloon catheter having an angioplasty, occlusive/drug delivery or photodynamic therapy (PDT) balloon, a stent delivery balloon or iontophoresis section, and an occlusive/drug delivery balloon in a distal end portion ofthe catheter. For this purpose, the multi-purpose balloon catheter ofthe present invention includes two or more lumens therein extending to the distal end portion ofthe multi-purpose balloon catheter. 2. Description of the related art including information disclosed under 37 CFR §§ 1.97- 1.99. Heretofore numerous balloon type catheters and perfusion catheters have been proposed for performing one or two procedures. However, heretofore, prior to the present invention a multi¬ purpose balloon catheter capable of performing three or more cardiovascular procedures has not been available.
Three non-analogous three balloon catheters are disclosed in the Solar U.S. Patent No. 4,546,759, the Landreneau U.S. Patent No. 4,681 ,564 and the Dalton U.S. Patent No. 5,315,992. A simultaneous angioplasty and drug delivery balloon is disclosed in PCT published patent application No. 95/05866.
Examples of catheters for delivering thrombolytic agents to a blood vessel are disclosed in the following U.S. Patents. U.S. Patent No. Patentee
4,968,307 Dake et al.
5,021,044 Sharkawy
5,279,546 Mische et al.
5,368,034 Isner 5,380,299 Fearnot et al.
Two methods for photodynamic therapy (PDT) treatment of blood vessels including use ofa balloon are disclosed in the Narciso, Jr. U.S. Patents Nos. 5,169,395 and 5,298,018.
Finally, an implantable system for myocardial iontophoretic delivery of medicinal materials to a heart is disclosed in U.S. Patent No. 5,087,243. SUMMARY OF THE INVENTION
According to the present invention there is provided a multi-purpose balloon catheter comprising a tubular body having a proximal end portion, a distal end portion and at least two lumens within the tubular body, and the distal end portion having three spaced apart balloons thereon, the distal balloon being an occlusive balloon, the middle balloon being a stent mounting balloon and the proximal balloon being an occlusive balloon.
Preferably the distal balloon is an angioplasty balloon and the proximal balloon is also a drug therapy balloon.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a plan view of the multi-purpose balloon catheter constructed according to the teachings ofthe present invention and shows a distal end portion ofthe catheter and a proximal end portion of the catheter. FIG. 2 is an enlarged view of the distal end portion of the catheter shown in FIG. 1 and shows a first angioplasty balloon, a second or middle stent mounting balloon and a third, occlusive/drug delivery balloon.
FIG. 3 is a sectional view taken along lines 3-3 of FIG. 2. FIG. 4 is a sectional view taken along lines 4-4 of FIG. 1. FIG. 5 is an enlarged cross-sectional view ofthe occlusive/drug delivery balloon shown in
FIG. 2.
FIG. 6 is a longitudinal view with portions cut away ofa section ofa blood vessel and shows the distal end portion of the multi-purpose balloon catheter of the present invention disposed therein and with the first, most distal, balloon thereof in an inflated condition. FIG. 7 is a longitudinal view ofthe blood vessel shown in FIG. 6 with portions cut away and shows the distal end portion of the multi-purpose balloon catheter therein, similar to the view shown in FIG. 5, but with a proximally located third, occlusive/drug delivery balloon also inflated.
FIG. 8 is a longitudinal view ofthe blood vessel shown in FIG. 6 with portions cut away and shows the distal end portion of the multi-purpose balloon catheter of the present invention disposed therein but with the angioplasty balloon and the thrombolysis balloon collapsed and with a stent mounting (delivery) balloon disposed between them inflated for the purpose of stent implantation.
FIG. 9 is a longitudinal view ofthe blood vessel shown in FIG. 6 with portions cut away and shows the distal end portion of the multi-purpose balloon catheter of the present invention disposed therein, similar to the view shown in FIG. 6, but shows an aneurysm in the portion ofthe blood vessel between the first, angioplasty balloon and the third occlusive/drug delivery balloon. DESCRIPTION OF THE PREFERRED EMBODIMENT(S)
Referring now to the drawings in greater detail, there is illustrated in FIG. 1 a multi-purpose balloon catheter 10 constructed according to the teachings of the invention and including a proximal end portion 12, a tubular body 14, and a distal end portion 16 including a distal tip 18. According to the teachings ofthe present invention, the distal end portion 16 includes a first, most distal, occlusive/angioplasty/photodynamic balloon 20, a second, or middle stent mounting or stent delivery balloon 22 capable of carrying a stent 24 thereon, which can be a metal stent or a thermoplastic stent, and a third, occlusive/drug delivery balloon 26.
As shown, the tip 18 has a distal ring electrode 30 which is electrically coupled with a distal ring electrode 32 located just proximally ofthe occlusive balloon 26.
Proximal of the ring electrode 32 are one or more, namely four, perfusion ports 34. Typically, the distal tip 18 is open at the outer end thereof to form a perfusion port 36 which is in communication with a perfusion lumen 38 within the tubular body 14 in the distal end portion 16 which is also in communication with the perfusion ports 34. The proximal end portion 12 includes four input tubings 41-44 connected to a coupling member 46 that couples through a strain relief sleeve 48 to the tubular body 14. Also coupled to the strain relief sleeve 48 is an electrical cable 50 having at least two insulated wire conductors 51 and 52 that extend through the tubular body to the electrodes 30, 32 and the stent 24. Wire conductor 51 connects to the ring electrodes 30 and 32 and wire conductor 52 connects to the stent 24.
FIG. 3 is a sectional view through the tubular body 14, is taken along lines 3-3 of FIG. 2 and shows the perfusion lumen 38, which is the largest lumen, a fluid delivery lumen 54 for the stent mounting balloon 22 directly above the perfusion lumen 38, a fluid delivery lumen 56 for the angioplasty balloon 20 which also can have a light delivery fiber 57 therein, and a fluid delivery lumen 58 for delivering a fluid and/or drug to the occlusive/drug delivery balloon 26.
FIG. 4 is a sectional view ofthe tubings 41-44 shown in FIG. 1 and is taken along line 4-4 of FIG. 1.
The multi-purpose balloon catheter 10 ofthe present invention can be utilized for performing a number of procedures which will now be described in greater detail in connection with the description of FIGS. 5-9. First of all, as shown in FIG. 5, the occlusive/drug balloon 26 has a proximal end 60 fixed on the tubular body just proximal to a fluid delivery inlet port 62. The balloon 26 has a distal end portion 64 which is inverted, or folded under itself, over the tubular body 14 and connected thereto as shown. Then, two or more outlet ports 66 are provided in an inwardly facing section 67 ofthe distal end portion 64 ofthe balloon 26.
The balloon construction for the third balloon 26 illustrated in FIG. 5 is preferred when the third balloon 26 is used for drug delivery and can be used with a saline solution for other procedures illustrated in FIGS. 7 and 9. However, for these procedures it is desirable to use a balloon not having the outlet ports 66. In FIG. 6, there is illustrated the distal end portion 16 ofthe multi-purpose balloon catheter
10 positioned in a blood vessel 70 and having the angioplasty balloon 20 inflated for an angioplasty procedure. If desired, the angioplasty balloon 20 can be made of a transparent or translucent plastic material and light can be supplied through the light delivery fiber 57 and directed through the transparent or translucent balloon 20 for photodynamic therapy. In FIG. 7, there is illustrated an iontophoresis procedure which can include drug delivery or thrombolysis. In this procedure, the first balloon 20 is only inflated sufficient to occlude the blood vessel 70 and the third, occlusive balloon 26 is supplied with a drug solution from the lumen 58 and the inlet port 62 which is used for both inflating the balloon 26 from the lumen 58 through the inlet port 62 and for delivering a drug solution through the outlet port 66 ofthe balloon 26 to the area in the blood vessel 70 between the first balloon 20 and the third balloon 26.
If desired, the stent 24 can be used as an electrode and for this purpose covered with a porous polycarbonate membrane 72, a fragmentary portion of which is shown in FIG. 7. This covering will prevent shorting ofthe stent electrode 24 to the inner wall ofthe blood vessel 70.
The iontophoresis electrical circuit is completed through a silver oxide (+) or silver (-) electrodes 30, 32 depending on the polarity needed.
Also, the first balloon 20 can be an inversion of the drug delivery balloon 26 and can be constructed in the same manner but as a mirror image ofthe balloon 26 shown in FIG. 5 whereby drug delivery is supplied through both the first and third balloons 20 and 26 which serve as occlusive and drug delivery balloons for this procedure. In FIG. 8 there is illustrated a stent implantation procedure where only the middle, second, stent delivery balloon 22 is inflated for implanting the stent 24. If desired, the stent 24 can be a drug delivery stent ofthe type disclosed in U.S. Patent Application Serial No. 08/304,163 filed on September 12, 1994 and entitled: RETRIEVABLE DRUG DELIVERY STENT, the disclosure of which is incorporated herein by reference. Also, a stent sheath for local drug delivery is disclosed in U.S. Patent No. 5,383,928.
Thus, in the procedure shown in FIG. 8, the stent 24 can be implanted and, if desired, utilized for delivery of a drug through the stent to the inner wall ofthe blood vessel 70.
In FIG. 9, there is illustrated the use ofthe multi-purpose balloon catheter 10 as a "bail-out catheter" where the first and third balloons are positioned on either side of an aneurysm or thrombosis and inflated to bridge the aneurysm. In this use ofthe multi-purpose balloon catheter
10, the third balloon 26 can be used to deliver a lysing agent 76 or other substance through the outlet ports 66 to the area of the aneurysm.
At the same time, blood can flow through the perfusion ports 34, then through the perfusion lumen 38 and out the perfusion outlet port 36 to maintain blood flow while the aneurysm 74 is being treated.
From the foregoing description, it will be apparent that the multi-purpose balloon catheter of the present invention has a number of advantages, some of which have been described above and others which are inherent in the invention.
Also, it is apparent that modifications can be made to the multi-purpose balloon catheter of the present invention without departing from the teachings ofthe invention. For example, a stent 24 can be omitted from the second balloon 22 when performing the procedures shown in FIGS. 6 and 9. Also, the balloon 26 can be constructed without outlet ports 66. Further, the first balloon 20 can have a mirror image construction ofthe balloon 26 (inverted from the construction shown in FIG. 5).
Accordingly, the scope of the invention is only to be limited as necessitated by the accompanying claims.

Claims

CLAIMS WE CLAIM:
1. A multi-purpose balloon catheter comprising a tubular body having a proximal end portion, a distal end portion, and at least two lumens within said tubular body, said distal end portion having three spaced apart balloons thereon, said balloons being positioned proximal, middle, and distal relative to each other, the distal balloon being an occlusive balloon, the middle balloon being a stent mounting balloon having a stent mounted thereon, and the proximal balloon being an occlusive balloon , one of said lumens communicating with said middle balloon, said tubular body defining at least one proximal perfusion port located proximally of said proximal balloon and at least one distal perfusion port located distally of said proximal perfusion port, the other of said lumens communicating between said proximal and distal perfusion ports.
2. The multi-purpose balloon catheter of Claim 1 , further comprising a third lumen defined by said tubular member that communicates with said proximal and distal balloons.
3. The multi-purpose balloon catheter of Claim 1, further comprising a third and fourth lumen defined by said tubular member, the third lumen communicating with said proximal balloon and the fourth lumen communicating with said distal balloon , said distal balloon being an angioplasty balloon.
4. The multi-purpose balloon catheter of Claim 1 , further comprising an electrode forming stent mounted about said middle balloon and an electric wire connected to said electrode forming stent which extends through said tubular body to said proximal end portion of said tubular body.
5. The multi-purpose balloon catheter of Claim 6 wherein said el ectrode forming stent has a microporous covering thereover to prevent shorting of said stent electrode to an interior wall of a blood vessel.
6. The multi-purpose balloon catheter of Claim 8 , wherein said second electrode is mounted on said tubular body distally of said distal balloon.
7. The multi-purpose balloon catheter of Claim 6 wherein said proximal balloon is a drug delivery balloon having an inwardly facing surface that faces inwardly toward said tubular body and defining drug delivery outlet ports that open onto the inwardly facing surface. 8. The multi-purpose balloon catheter of Claim 3, wherein said at least one proximal perfusion port is located proximally of said proximal balloon and said at least one distal perfusion port is located distal to said distal balloon. 2 PC17US96/20903
8
9. The multi-purpose balloon catheter of claim 1 wherein said distal balloon is a drug delivery balloon.
10. A multi-purpose balloon catheter, comprising: a tubular catheter body having a proximal and distal end portion, said tubular body defining a proximal and distal perfusion port, the tubular body further defining an inflation lumen and a perfusion lumen, the perfusion lumen providing fluid communication between the proximal and distal perfusion ports; a first, second and third balloon affixed to said distal end portion of the tubular body and being longitudinally spaced from each other, said first balloon being an occlusive balloon positioned proximal ofthe second balloon, and the second balloon being a stent mounting balloon positioned proximal ofthe third balloon, the third balloon being an occlusive balloon; a hub affixed to the proximal end portion of the tubular body and defining an inflation port, the inflation lumen providing fluid communication between the inflation port and the second balloon; and a flexible stent mounted on and crimped about said middle balloon.
1 1. A multi-purpose balloon catheter, comprising a tubular body having a proximal end portion, a distal end portion, and defining at least two lumens within said tubular body, said distal end portion having three spaced apart balloons thereon, said balloons being positioned proximal, middle, and distal relative to each other, the distal balloon being an occlusive balloon, the middle balloon being a stent mounting balloon and the proximal balloon being an occlusive balloon, wherein said middle balloon has an electrode forming stent mounted thereon, and said tubular body has an electric wire connected to said electrode forming stent which extends through said tubular body to said proximal end portion, wherein said proximal balloon is a drug delivery balloon and has drug delivery outlet ports that open onto an inwardly facing surface of said proximal balloon that faces inwardly toward said tubular body.
12. A multi-purpose balloon catheter, comprising: a tubular catheter body having a proximal and distal end portion, said tubular body defining a first, second and third inflation lumen; a first, second and third balloon affixed to said distal end portion of the tubular body and being longitudinally spaced from each other, said first balloon being a relatively elastic occlusive balloon positioned proximal ofthe second balloon, and the second balloon being a stent mounting balloon positioned proximal of the third balloon, the third balloon being a relatively inelastic angioplasty balloon; a hub affixed to the proximal end portion of the tubular body and defining a first, second and third inflation port, wherein the first, second and third inflation lumen provide fluid communication between the first, second and third inflation port and the first, second and third balloon, respectively.
13. The multi-purpose balloon catheter of Claim 20, further comprising an electrode mounted about the second balloon, and an electrically conductive wire which extends through said tubular body to said proximal end portion of said tubular body, said electrode being coupled to said wire.
14. The multi-purpose balloon catheter of Claim 20, wherein said proximal balloon is a drug delivery balloon and defines at least one drug delivery outlet port.
15. A multi-purpose balloon catheter, comprising: a tubular catheter body having a proximal and distal end portion, said tubular body defining a first, second and third inflation lumen; a first, second and third balloon affixed to said distal end portion of the tubular body and being longitudinally spaced from each other, said first balloon being a relatively elastic occlusive balloon positioned proximal ofthe second balloon, and the second balloon being a stent mounting balloon positioned proximal ofthe third balloon, the third balloon being a transparent or translucent photodynamic therapy balloon; wherein said first, second and third inflation lumen communicate with the first, second and third balloon, respectively; and a light delivery fiber extending within the tubular body to said third balloon to provide light energy to the interior of the third balloon.
16. The multi-purpose balloon catheter of Claim 23, further comprising at least one proximal perfusion port located proximally of said proximal balloon and at least one distal perfusion port located distally of said proximal perfusion port being defined by said tubular body, and a perfusion lumen communicating between said proximal and distal perfusion ports.
PCT/US1996/020903 1995-12-28 1996-12-20 Multipurpose balloon catheter WO1997024154A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP96945449A EP0935479B1 (en) 1995-12-28 1996-12-20 Multipurpose balloon catheter
DE69633410T DE69633410T2 (en) 1995-12-28 1996-12-20 MULTI BALLOON CATHETER
CA002241176A CA2241176C (en) 1995-12-28 1996-12-20 Multipurpose balloon catheter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/580,161 US5728068A (en) 1994-06-14 1995-12-28 Multi-purpose balloon catheter
US08/580,161 1995-12-28

Publications (1)

Publication Number Publication Date
WO1997024154A1 true WO1997024154A1 (en) 1997-07-10

Family

ID=24319962

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/020903 WO1997024154A1 (en) 1995-12-28 1996-12-20 Multipurpose balloon catheter

Country Status (4)

Country Link
US (1) US5728068A (en)
EP (1) EP0935479B1 (en)
DE (1) DE69633410T2 (en)
WO (1) WO1997024154A1 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006096A1 (en) * 1997-07-30 1999-02-11 Johannes Rieger Balloon dilatation catheter
EP0920882A3 (en) * 1997-12-04 2000-01-05 Schneider Inc. Balloon dilatation-drug delivery catheter and stent deployment-drug delivery catheter in rapid exchange configuration
GR1003402B (en) * 1999-02-03 2000-07-11 Catheter for protected angioplastic operation on the artery branch
US6231588B1 (en) 1998-08-04 2001-05-15 Percusurge, Inc. Low profile catheter for angioplasty and occlusion
WO2004012589A2 (en) * 2002-08-05 2004-02-12 Miravant Medical Technologies, Inc. Catheter for diagnosis and treatment of diseased vessels
EP1469902A2 (en) * 2002-02-01 2004-10-27 Robert J. Goldman Multi-function catheter and use thereof
US7396354B2 (en) 2002-08-05 2008-07-08 Rychnovsky Steven J Light delivery catheter
WO2010011602A1 (en) * 2008-07-23 2010-01-28 Boston Scientific Scimed, Inc. Occlusion crossing device and method
US8062251B2 (en) 2002-02-01 2011-11-22 Vascular Designs, Inc. Multi-function catheter and use thereof
EP3932340A1 (en) * 2020-06-29 2022-01-05 Neuravi Limited Isolated stenting with distal balloon

Families Citing this family (374)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK124690D0 (en) 1990-05-18 1990-05-18 Henning Rud Andersen FAT PROTECTION FOR IMPLEMENTATION IN THE BODY FOR REPLACEMENT OF NATURAL FLEET AND CATS FOR USE IN IMPLEMENTING A SUCH FAT PROTECTION
US6039749A (en) 1994-02-10 2000-03-21 Endovascular Systems, Inc. Method and apparatus for deploying non-circular stents and graftstent complexes
US5857998A (en) * 1994-06-30 1999-01-12 Boston Scientific Corporation Stent and therapeutic delivery system
US6117124A (en) * 1996-01-26 2000-09-12 Parodi; Juan Carlos Device and method to do arteriographies and angioplasties with a balloon and without injecting a contrasting media in the vessel lumen
US8123737B2 (en) * 1996-04-10 2012-02-28 Sorin Group Usa, Inc. Multichannel catheter
US5868703A (en) * 1996-04-10 1999-02-09 Endoscopic Technologies, Inc. Multichannel catheter
US20010029349A1 (en) * 1996-04-12 2001-10-11 Boris Leschinsky Method and apparatus for treating aneurysms
NL1003043C2 (en) * 1996-05-06 1997-11-07 Paul Ferdinand Schouwenburg Set for the insertion of a voice prosthesis in laryngectomers.
US6913763B2 (en) 1996-11-19 2005-07-05 Intrabrain International Nv Method and device for enhanced delivery of a biologically active agent through the spinal spaces into the central nervous system of a mammal
US7033598B2 (en) * 1996-11-19 2006-04-25 Intrabrain International N.V. Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
EP0850607A1 (en) 1996-12-31 1998-07-01 Cordis Corporation Valve prosthesis for implantation in body channels
US5908407A (en) * 1997-07-25 1999-06-01 Neuroperfusion, Inc. Retroperfusion catheter apparatus and method
US6070589A (en) 1997-08-01 2000-06-06 Teramed, Inc. Methods for deploying bypass graft stents
US6135981A (en) * 1997-10-22 2000-10-24 Dyke; Charles C. Protective aortic occlusion catheter
DE69725324T2 (en) * 1997-10-23 2004-08-05 Schneider (Europe) Gmbh Seal for a catheter device with dilatation and occlusion balloon
US6656215B1 (en) 2000-11-16 2003-12-02 Cordis Corporation Stent graft having an improved means for attaching a stent to a graft
US6290731B1 (en) 1998-03-30 2001-09-18 Cordis Corporation Aortic graft having a precursor gasket for repairing an abdominal aortic aneurysm
US6219577B1 (en) 1998-04-14 2001-04-17 Global Vascular Concepts, Inc. Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
US6287314B1 (en) * 1998-04-21 2001-09-11 Advanced Cardiovascular Systems, Inc. Stent deploying catheter system
US6267747B1 (en) 1998-05-11 2001-07-31 Cardeon Corporation Aortic catheter with porous aortic root balloon and methods for inducing cardioplegic arrest
US6461327B1 (en) * 1998-08-07 2002-10-08 Embol-X, Inc. Atrial isolator and method of use
US6210365B1 (en) * 1998-08-14 2001-04-03 Cardiovention, Inc. Perfusion catheter system having sutureless arteriotomy seal and methods of use
US6022359A (en) * 1999-01-13 2000-02-08 Frantzen; John J. Stent delivery system featuring a flexible balloon
US6048350A (en) 1999-06-14 2000-04-11 Scimed Life Systems, Inc. Segmented balloon delivery system
US6280412B1 (en) 1999-06-17 2001-08-28 Scimed Life Systems, Inc. Stent securement by balloon modification
US6364900B1 (en) * 1999-07-14 2002-04-02 Richard R. Heuser Embolism prevention device
US20070265563A1 (en) * 2006-05-11 2007-11-15 Heuser Richard R Device for treating chronic total occlusion
WO2001019445A1 (en) * 1999-09-17 2001-03-22 Advanced Cardiovascular Systems, Inc. Balloon catheter to deliver a drug or to remove substances such as emboli or excess drug
US6217589B1 (en) * 1999-10-27 2001-04-17 Scimed Life Systems, Inc. Retrieval device made of precursor alloy cable and method of manufacturing
US7184827B1 (en) * 2000-01-24 2007-02-27 Stuart D. Edwards Shrinkage of dilatations in the body
US6808534B1 (en) * 2000-02-16 2004-10-26 Endovascular Technologies, Inc. Collapsible jacket guard
US6485500B1 (en) * 2000-03-21 2002-11-26 Advanced Cardiovascular Systems, Inc. Emboli protection system
US6454799B1 (en) * 2000-04-06 2002-09-24 Edwards Lifesciences Corporation Minimally-invasive heart valves and methods of use
US6854467B2 (en) * 2000-05-04 2005-02-15 Percardia, Inc. Methods and devices for delivering a ventricular stent
US6658288B1 (en) * 2000-05-05 2003-12-02 Endovascular Technologies, Inc. Apparatus and method for aiding thrombosis through the application of electric potential
US6685672B1 (en) * 2000-07-13 2004-02-03 Edwards Lifesciences Corporation Multi-balloon drug delivery catheter for angiogenesis
JP2004506469A (en) 2000-08-18 2004-03-04 アトリテック, インコーポレイテッド Expandable implantable device for filtering blood flow from the atrial appendage
US6585926B1 (en) 2000-08-31 2003-07-01 Advanced Cardiovascular Systems, Inc. Method of manufacturing a porous balloon
US6695833B1 (en) * 2000-09-27 2004-02-24 Nellix, Inc. Vascular stent-graft apparatus and forming method
US6514237B1 (en) 2000-11-06 2003-02-04 Cordis Corporation Controllable intralumen medical device
US7314483B2 (en) * 2000-11-16 2008-01-01 Cordis Corp. Stent graft with branch leg
US6733525B2 (en) 2001-03-23 2004-05-11 Edwards Lifesciences Corporation Rolled minimally-invasive heart valves and methods of use
US7556646B2 (en) 2001-09-13 2009-07-07 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US6609521B1 (en) 2001-04-09 2003-08-26 Regents Of The University Of Minnesota Endotracheal tube
US6685745B2 (en) * 2001-05-15 2004-02-03 Scimed Life Systems, Inc. Delivering an agent to a patient's body
US8771302B2 (en) * 2001-06-29 2014-07-08 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US7544206B2 (en) 2001-06-29 2009-06-09 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US20060201351A1 (en) * 2001-07-02 2006-09-14 Gi View Ltd. Self-propelled imaging system
US6863683B2 (en) 2001-09-19 2005-03-08 Abbott Laboratoris Vascular Entities Limited Cold-molding process for loading a stent onto a stent delivery system
US7083639B2 (en) * 2001-09-26 2006-08-01 Medtronic Vascular, Inc. Stent delivery catheter with grooved balloon and methods of making same
US6893460B2 (en) * 2001-10-11 2005-05-17 Percutaneous Valve Technologies Inc. Implantable prosthetic valve
US20030109915A1 (en) * 2001-12-07 2003-06-12 Don Michael T. Anthony Distal protection double balloon catheter
US7169171B2 (en) * 2001-12-07 2007-01-30 Don Michael T Anthony Distal protection double balloon catheter
US7326237B2 (en) * 2002-01-08 2008-02-05 Cordis Corporation Supra-renal anchoring prosthesis
US20110306997A9 (en) * 2002-02-21 2011-12-15 Roschak Edmund J Devices for creating passages and sensing for blood vessels
US7131963B1 (en) 2002-06-27 2006-11-07 Advanced Cardiovascular Systems, Inc. Catheters and methods of using catheters
US7148342B2 (en) * 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
US20040034336A1 (en) * 2002-08-08 2004-02-19 Neal Scott Charged liposomes/micelles with encapsulted medical compounds
EP1542616B1 (en) 2002-09-20 2015-04-22 Endologix, Inc. Stent-graft with positioning anchor
US7300459B2 (en) * 2002-10-17 2007-11-27 Heuser Richard R Stent with covering and differential dilation
US7166088B2 (en) 2003-01-27 2007-01-23 Heuser Richard R Catheter introducer system
WO2004073794A2 (en) * 2003-02-19 2004-09-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Device, methods and sponges for iontophoretic drug delivery
FR2851922B1 (en) * 2003-03-03 2007-01-05 Perouse Laboratoires DEVICE FOR PRODUCING ANASTOMOSES
US7399315B2 (en) 2003-03-18 2008-07-15 Edwards Lifescience Corporation Minimally-invasive heart valve with cusp positioners
US7517342B2 (en) * 2003-04-29 2009-04-14 Boston Scientific Scimed, Inc. Polymer coated device for electrically medicated drug delivery
US20040260394A1 (en) * 2003-06-20 2004-12-23 Medtronic Vascular, Inc. Cardiac valve annulus compressor system
US8308682B2 (en) * 2003-07-18 2012-11-13 Broncus Medical Inc. Devices for maintaining patency of surgically created channels in tissue
US8002740B2 (en) * 2003-07-18 2011-08-23 Broncus Technologies, Inc. Devices for maintaining patency of surgically created channels in tissue
US20050036059A1 (en) * 2003-08-13 2005-02-17 Benad Goldwasser Ingestible imaging system
US7833176B2 (en) * 2003-08-13 2010-11-16 G. I. View Ltd. Pressure-propelled system for body lumen
US20050038319A1 (en) * 2003-08-13 2005-02-17 Benad Goldwasser Gastrointestinal tool over guidewire
US20050038318A1 (en) * 2003-08-13 2005-02-17 Benad Goldwasser Gastrointestinal tool over guidewire
US7402141B2 (en) * 2003-08-27 2008-07-22 Heuser Richard R Catheter guidewire system using concentric wires
US20090041823A1 (en) * 2003-09-19 2009-02-12 Axel Larena-Avellaneda Agent-releasing Vascular Prosthesis
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US20050075725A1 (en) * 2003-10-02 2005-04-07 Rowe Stanton J. Implantable prosthetic valve with non-laminar flow
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US8343213B2 (en) * 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US20050137687A1 (en) 2003-12-23 2005-06-23 Sadra Medical Heart valve anchor and method
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US20120041550A1 (en) 2003-12-23 2012-02-16 Sadra Medical, Inc. Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
AU2004308508B2 (en) 2003-12-23 2011-03-10 Sadra Medical, Inc. Repositionable heart valve
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
US7635345B2 (en) * 2004-01-09 2009-12-22 G. I. View Ltd. Pressure-propelled system for body lumen
US7635346B2 (en) * 2004-01-09 2009-12-22 G. I. View Ltd. Pressure-propelled system for body lumen
US8419678B2 (en) 2004-01-09 2013-04-16 G.I. View Ltd. Pressure-propelled system for body lumen
US7947013B2 (en) * 2004-01-09 2011-05-24 G.I. View Ltd. Pressure-propelled system for body lumen
JP4680939B2 (en) * 2004-02-10 2011-05-11 シネコー・エルエルシー Therapeutic intravascular delivery system
US20050226991A1 (en) * 2004-04-07 2005-10-13 Hossainy Syed F Methods for modifying balloon of a catheter assembly
US20050265960A1 (en) * 2004-05-26 2005-12-01 Pacetti Stephen D Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same
US8496580B2 (en) 2004-05-14 2013-07-30 G.I. View Ltd. Omnidirectional and forward-looking imaging device
US7537580B2 (en) * 2004-06-23 2009-05-26 Boston Scientific Scimed, Inc. Intravascular dilatation infusion catheter
US8409167B2 (en) 2004-07-19 2013-04-02 Broncus Medical Inc Devices for delivering substances through an extra-anatomic opening created in an airway
US8048145B2 (en) 2004-07-22 2011-11-01 Endologix, Inc. Graft systems having filling structures supported by scaffolds and methods for their use
US7387610B2 (en) 2004-08-19 2008-06-17 Cardiac Pacemakers, Inc. Thoracic impedance detection with blood resistivity compensation
US20090012429A1 (en) * 2004-08-25 2009-01-08 Heuser Richard R Catheter guidewire system using concentric wires
US8545418B2 (en) 2004-08-25 2013-10-01 Richard R. Heuser Systems and methods for ablation of occlusions within blood vessels
US7648727B2 (en) * 2004-08-26 2010-01-19 Advanced Cardiovascular Systems, Inc. Methods for manufacturing a coated stent-balloon assembly
EP1655001A1 (en) * 2004-11-08 2006-05-10 Inderbitzi, Rolf, Dr. med. Vascular prosthesis with attachment means and connecting means
EP2361545B1 (en) * 2005-01-06 2014-03-12 G.I. View Ltd. Gastrointestinal tool over guiding element
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
US10080481B2 (en) * 2005-02-10 2018-09-25 G.I. View Ltd. Advancement techniques for gastrointestinal tool with guiding element
US7962208B2 (en) 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US8052668B2 (en) * 2005-05-13 2011-11-08 Cardiac Pacemakers, Inc. Neurotoxic agents and devices to treat atrial fibrillation
US7780723B2 (en) 2005-06-13 2010-08-24 Edwards Lifesciences Corporation Heart valve delivery system
JP2009500121A (en) * 2005-07-07 2009-01-08 ネリックス・インコーポレーテッド System and method for treatment of an intraluminal aneurysm
US20090182197A1 (en) * 2005-08-01 2009-07-16 G.I. View Ltd. Tools for use in small intestine
WO2007015241A2 (en) * 2005-08-01 2007-02-08 G.I. View Ltd. Tools for use in esophagus
US8430809B2 (en) 2005-08-01 2013-04-30 G. I View Ltd. Capsule for use in small intestine
EP1917062B1 (en) * 2005-08-19 2009-10-21 Abbott Laboratories Vascular Enterprises Limited Method of producing a balloon of a balloon catheter and balloon
US8167932B2 (en) 2005-10-18 2012-05-01 Edwards Lifesciences Corporation Heart valve delivery system with valve catheter
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US20070142819A1 (en) * 2005-12-20 2007-06-21 El-Nounou Fozan O Bifurcated catheter for agent delivery and method of agent delivery
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US20070150041A1 (en) * 2005-12-22 2007-06-28 Nellix, Inc. Methods and systems for aneurysm treatment using filling structures
WO2007081530A2 (en) * 2006-01-03 2007-07-19 Med Institute, Inc. Endoluminal medical device for local delivery of cathepsin inhibitors
US7374567B2 (en) * 2006-01-25 2008-05-20 Heuser Richard R Catheter system for connecting adjacent blood vessels
US20070185567A1 (en) * 2006-01-25 2007-08-09 Heuser Richard R Catheter system with stent device for connecting adjacent blood vessels
US8062321B2 (en) 2006-01-25 2011-11-22 Pq Bypass, Inc. Catheter system for connecting adjacent blood vessels
WO2007097983A2 (en) 2006-02-14 2007-08-30 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US20070239254A1 (en) * 2006-04-07 2007-10-11 Chris Chia System for percutaneous delivery and removal of a prosthetic valve
US7442207B2 (en) * 2006-04-21 2008-10-28 Medtronic Vascular, Inc. Device, system, and method for treating cardiac valve regurgitation
US8551161B2 (en) 2006-04-25 2013-10-08 Medtronic Vascular, Inc. Cardiac valve annulus restraining device
US8003156B2 (en) 2006-05-04 2011-08-23 Advanced Cardiovascular Systems, Inc. Rotatable support elements for stents
WO2007133758A1 (en) * 2006-05-15 2007-11-22 Physical Pharmaceutica, Llc Composition and improved method for preparation of small particles
US20080152654A1 (en) * 2006-06-12 2008-06-26 Exegenics, Inc., D/B/A Opko Health, Inc. COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ANGIOGENESIS
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
US8048448B2 (en) 2006-06-15 2011-11-01 Abbott Cardiovascular Systems Inc. Nanoshells for drug delivery
US8333000B2 (en) 2006-06-19 2012-12-18 Advanced Cardiovascular Systems, Inc. Methods for improving stent retention on a balloon catheter
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
US9408607B2 (en) 2009-07-02 2016-08-09 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
WO2008016578A2 (en) 2006-07-31 2008-02-07 Cartledge Richard G Sealable endovascular implants and methods for their use
US9585743B2 (en) 2006-07-31 2017-03-07 Edwards Lifesciences Cardiaq Llc Surgical implant devices and methods for their manufacture and use
EP1978895B1 (en) 2006-09-08 2010-06-09 Edwards Lifesciences Corporation Integrated heart valve delivery system
US7872118B2 (en) * 2006-09-08 2011-01-18 Opko Ophthalmics, Llc siRNA and methods of manufacture
US8236045B2 (en) 2006-12-22 2012-08-07 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method of making the same
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US8048441B2 (en) 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
US9566178B2 (en) 2010-06-24 2017-02-14 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US8100820B2 (en) * 2007-08-22 2012-01-24 Edwards Lifesciences Corporation Implantable device for treatment of ventricular dilation
DE102007043830A1 (en) 2007-09-13 2009-04-02 Lozonschi, Lucian, Madison Heart valve stent
US8425593B2 (en) 2007-09-26 2013-04-23 St. Jude Medical, Inc. Collapsible prosthetic heart valves
US9532868B2 (en) 2007-09-28 2017-01-03 St. Jude Medical, Inc. Collapsible-expandable prosthetic heart valves with structures for clamping native tissue
US7828840B2 (en) * 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
PL3643273T3 (en) 2007-12-14 2021-12-06 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US8236039B2 (en) * 2007-12-21 2012-08-07 Abbott Laboratories Vena cava filter having wall contacts
ES2903231T3 (en) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
WO2009108942A1 (en) 2008-02-29 2009-09-03 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
EP2278939B1 (en) 2008-04-25 2021-04-14 Endologix LLC Stent graft delivery system
US20090276040A1 (en) 2008-05-01 2009-11-05 Edwards Lifesciences Corporation Device and method for replacing mitral valve
US9061119B2 (en) * 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
CA2726596A1 (en) * 2008-06-04 2009-12-10 Nellix, Inc. Sealing apparatus and methods of use
HUE054943T2 (en) 2008-06-06 2021-10-28 Edwards Lifesciences Corp Low profile transcatheter heart valve
EP2306930A4 (en) * 2008-06-10 2015-07-29 Univ Cornell Method and apparatus for repairing vascular abnormalties and/or other body lumen abnormalties using an endoluminal approach and a flowable forming material
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
EP4176845A1 (en) 2008-07-15 2023-05-10 St. Jude Medical, LLC Collapsible and re-expandable prosthetic heart valve cuff designs
KR101489989B1 (en) * 2008-07-30 2015-02-04 지.아이. 뷰 리미티드 System and method for enhanced maneuverability
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US8118830B2 (en) * 2008-09-16 2012-02-21 Salviac Limited Method for reducing emboli formation
US8690936B2 (en) 2008-10-10 2014-04-08 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
US8790387B2 (en) 2008-10-10 2014-07-29 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
AU2009321185B2 (en) 2008-11-03 2014-05-01 G.I. View Ltd Remote pressure sensing system and method thereof
US8470792B2 (en) 2008-12-04 2013-06-25 Opko Pharmaceuticals, Llc. Compositions and methods for selective inhibition of VEGF
EP2668934B1 (en) 2008-12-12 2017-05-10 Abbott Laboratories Vascular Enterprises Limited Process for loading a stent onto a stent delivery system
US20100217382A1 (en) * 2009-02-25 2010-08-26 Edwards Lifesciences Mitral valve replacement with atrial anchoring
US8439970B2 (en) 2009-07-14 2013-05-14 Edwards Lifesciences Corporation Transapical delivery system for heart valves
US20110106234A1 (en) * 2009-10-30 2011-05-05 Axel Grandt Interluminal medical treatment devices and methods
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
EP3649985B8 (en) 2009-12-08 2021-04-21 Avalon Medical Ltd. Device and system for transcatheter mitral valve replacement
US20110276078A1 (en) 2009-12-30 2011-11-10 Nellix, Inc. Filling structure for a graft system and methods of use
US8147526B2 (en) * 2010-02-26 2012-04-03 Kyphon Sarl Interspinous process spacer diagnostic parallel balloon catheter and methods of use
US8795354B2 (en) 2010-03-05 2014-08-05 Edwards Lifesciences Corporation Low-profile heart valve and delivery system
JP2013526388A (en) 2010-05-25 2013-06-24 イエナバルブ テクノロジー インク Artificial heart valve, and transcatheter delivery prosthesis comprising an artificial heart valve and a stent
JP5848345B2 (en) 2010-07-09 2016-01-27 ハイライフ エスエーエス Transcatheter atrioventricular valve prosthesis
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
CN106073946B (en) 2010-09-10 2022-01-04 西美蒂斯股份公司 Valve replacement device, delivery device for a valve replacement device and method of producing a valve replacement device
CA2813419C (en) 2010-10-05 2019-12-17 Edwards Lifesciences Corporation Prosthetic heart valve
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
US8801768B2 (en) 2011-01-21 2014-08-12 Endologix, Inc. Graft systems having semi-permeable filling structures and methods for their use
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
JP2012200368A (en) 2011-03-24 2012-10-22 Terumo Corp Stent delivery system
JP5976777B2 (en) 2011-04-06 2016-08-24 エンドーロジックス インコーポレイテッド Methods and systems for the treatment of intravascular aneurysms
EP2520251A1 (en) 2011-05-05 2012-11-07 Symetis SA Method and Apparatus for Compressing Stent-Valves
US8709034B2 (en) 2011-05-13 2014-04-29 Broncus Medical Inc. Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall
US9345532B2 (en) 2011-05-13 2016-05-24 Broncus Medical Inc. Methods and devices for ablation of tissue
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US9011374B2 (en) 2011-06-10 2015-04-21 Cook Medical Technologies Llc Balloon catheter with three lumens
WO2013009975A1 (en) 2011-07-12 2013-01-17 Boston Scientific Scimed, Inc. Coupling system for medical devices
US8795357B2 (en) 2011-07-15 2014-08-05 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US9339384B2 (en) 2011-07-27 2016-05-17 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9827093B2 (en) 2011-10-21 2017-11-28 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
WO2013078235A1 (en) 2011-11-23 2013-05-30 Broncus Medical Inc Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
CA2857997C (en) 2011-12-09 2021-01-05 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US10172708B2 (en) 2012-01-25 2019-01-08 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
CA3097321A1 (en) 2012-02-22 2013-08-29 Edwards Lifesciences Cardiaq Llc Actively controllable stent, stent graft, heart valve and method of controlling same
US9883941B2 (en) 2012-06-19 2018-02-06 Boston Scientific Scimed, Inc. Replacement heart valve
WO2014022124A1 (en) 2012-07-28 2014-02-06 Tendyne Holdings, Inc. Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
US20140067048A1 (en) 2012-09-06 2014-03-06 Edwards Lifesciences Corporation Heart Valve Sealing Devices
EP2922592B1 (en) 2012-11-21 2022-09-21 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic heart valves
US9415154B2 (en) * 2012-11-26 2016-08-16 Boston Scientific Neuromodulation Corporation Systems and methods for making and using an electrical stimulation system with photonic stimulation capabilities
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US10201638B2 (en) 2013-03-14 2019-02-12 Endologix, Inc. Systems and methods for forming materials in situ within a medical device
US10463489B2 (en) 2013-04-02 2019-11-05 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US11224510B2 (en) 2013-04-02 2022-01-18 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US10478293B2 (en) 2013-04-04 2019-11-19 Tendyne Holdings, Inc. Retrieval and repositioning system for prosthetic heart valve
ES2908132T3 (en) 2013-05-20 2022-04-27 Edwards Lifesciences Corp Prosthetic Heart Valve Delivery Apparatus
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
WO2014210124A1 (en) 2013-06-25 2014-12-31 Mark Christianson Thrombus management and structural compliance features for prosthetic heart valves
JP6465883B2 (en) 2013-08-01 2019-02-06 テンダイン ホールディングス,インコーポレイテッド Epicardial anchor device and method
SG10201805117UA (en) 2013-08-12 2018-07-30 Mitral Valve Tech Sarl Apparatus and methods for implanting a replacement heart valve
CN105491978A (en) 2013-08-30 2016-04-13 耶拿阀门科技股份有限公司 Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
WO2015058039A1 (en) 2013-10-17 2015-04-23 Robert Vidlund Apparatus and methods for alignment and deployment of intracardiac devices
US9788944B2 (en) * 2013-10-21 2017-10-17 St. Jude Medical, Cardiology Division, Inc. Transcatheter valve implantation access sheaths
ES2773255T3 (en) 2013-10-28 2020-07-10 Tendyne Holdings Inc Prosthetic heart valve and systems to supply it
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9913715B2 (en) 2013-11-06 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak sealing mechanism
CN111419472B (en) 2013-11-11 2023-01-10 爱德华兹生命科学卡迪尔克有限责任公司 System and method for manufacturing stent frames
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
US10098734B2 (en) 2013-12-05 2018-10-16 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
WO2015120122A2 (en) 2014-02-05 2015-08-13 Robert Vidlund Apparatus and methods for transfemoral delivery of prosthetic mitral valve
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
CA2937566C (en) 2014-03-10 2023-09-05 Tendyne Holdings, Inc. Devices and methods for positioning and monitoring tether load for prosthetic mitral valve
US10154904B2 (en) 2014-04-28 2018-12-18 Edwards Lifesciences Corporation Intravascular introducer devices
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US10195026B2 (en) 2014-07-22 2019-02-05 Edwards Lifesciences Corporation Mitral valve anchoring
US10058424B2 (en) 2014-08-21 2018-08-28 Edwards Lifesciences Corporation Dual-flange prosthetic valve frame
US10016272B2 (en) 2014-09-12 2018-07-10 Mitral Valve Technologies Sarl Mitral repair and replacement devices and methods
US20160144156A1 (en) 2014-11-20 2016-05-26 Edwards Lifesciences Corporation Inflatable device with etched modifications
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
CR20170245A (en) 2014-12-05 2017-09-14 Edwards Lifesciences Corp DIRIGIBLE CATETER WITH TRACTION CABLE
EP3242630A2 (en) 2015-01-07 2017-11-15 Tendyne Holdings, Inc. Prosthetic mitral valves and apparatus and methods for delivery of same
WO2016115375A1 (en) 2015-01-16 2016-07-21 Boston Scientific Scimed, Inc. Displacement based lock and release mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
EP3884906A1 (en) 2015-02-05 2021-09-29 Tendyne Holdings, Inc. Expandable epicardial pads and devices and methods for delivery of same
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10285809B2 (en) 2015-03-06 2019-05-14 Boston Scientific Scimed Inc. TAVI anchoring assist device
EP3267950A4 (en) 2015-03-11 2018-03-21 Board of Regents of the University of Nebraska Automated retrievable hemorrhage control system
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
US10327896B2 (en) 2015-04-10 2019-06-25 Edwards Lifesciences Corporation Expandable sheath with elastomeric cross sectional portions
US10792471B2 (en) 2015-04-10 2020-10-06 Edwards Lifesciences Corporation Expandable sheath
US10064718B2 (en) 2015-04-16 2018-09-04 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
AU2016248314B2 (en) 2015-04-16 2020-05-21 Tendyne Holdings, Inc. Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves
US10010417B2 (en) 2015-04-16 2018-07-03 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
WO2016177562A1 (en) 2015-05-01 2016-11-10 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US10195392B2 (en) 2015-07-02 2019-02-05 Boston Scientific Scimed, Inc. Clip-on catheter
US10335277B2 (en) 2015-07-02 2019-07-02 Boston Scientific Scimed Inc. Adjustable nosecone
US10179041B2 (en) 2015-08-12 2019-01-15 Boston Scientific Scimed Icn. Pinless release mechanism
US10136991B2 (en) 2015-08-12 2018-11-27 Boston Scientific Scimed Inc. Replacement heart valve implant
US10179046B2 (en) 2015-08-14 2019-01-15 Edwards Lifesciences Corporation Gripping and pushing device for medical instrument
US11026788B2 (en) 2015-08-20 2021-06-08 Edwards Lifesciences Corporation Loader and retriever for transcatheter heart valve, and methods of crimping transcatheter heart valve
US10588744B2 (en) 2015-09-04 2020-03-17 Edwards Lifesciences Corporation Delivery system for prosthetic heart valve
US10327894B2 (en) 2015-09-18 2019-06-25 Tendyne Holdings, Inc. Methods for delivery of prosthetic mitral valves
US10350067B2 (en) 2015-10-26 2019-07-16 Edwards Lifesciences Corporation Implant delivery capsule
US11259920B2 (en) 2015-11-03 2022-03-01 Edwards Lifesciences Corporation Adapter for prosthesis delivery device and methods of use
US10376364B2 (en) 2015-11-10 2019-08-13 Edwards Lifesciences Corporation Implant delivery capsule
US10470876B2 (en) 2015-11-10 2019-11-12 Edwards Lifesciences Corporation Transcatheter heart valve for replacing natural mitral valve
US10321996B2 (en) 2015-11-11 2019-06-18 Edwards Lifesciences Corporation Prosthetic valve delivery apparatus having clutch mechanism
US10265169B2 (en) 2015-11-23 2019-04-23 Edwards Lifesciences Corporation Apparatus for controlled heart valve delivery
US11033387B2 (en) 2015-11-23 2021-06-15 Edwards Lifesciences Corporation Methods for controlled heart valve delivery
US10583007B2 (en) 2015-12-02 2020-03-10 Edwards Lifesciences Corporation Suture deployment of prosthetic heart valve
JP2018535754A (en) 2015-12-03 2018-12-06 テンダイン ホールディングス,インコーポレイテッド Frame features for artificial mitral valves
US10357351B2 (en) 2015-12-04 2019-07-23 Edwards Lifesciences Corporation Storage assembly for prosthetic valve
JP6795591B2 (en) 2015-12-28 2020-12-02 テンダイン ホールディングス,インコーポレイテッド Atrial pocket closure for artificial heart valve
US10342660B2 (en) 2016-02-02 2019-07-09 Boston Scientific Inc. Tensioned sheathing aids
KR20170094820A (en) * 2016-02-11 2017-08-22 주식회사 바이오알파 Medical catheter device
US10179043B2 (en) 2016-02-12 2019-01-15 Edwards Lifesciences Corporation Prosthetic heart valve having multi-level sealing member
US10779941B2 (en) 2016-03-08 2020-09-22 Edwards Lifesciences Corporation Delivery cylinder for prosthetic implant
US11219746B2 (en) 2016-03-21 2022-01-11 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10799677B2 (en) 2016-03-21 2020-10-13 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10799676B2 (en) 2016-03-21 2020-10-13 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
CR20180410A (en) 2016-03-24 2019-04-01 Edwards Lifesciences Corp Delivery system for prosthetic heart valve
US10617851B2 (en) 2016-03-31 2020-04-14 Covidien Lp Medical catheter system
US10470877B2 (en) 2016-05-03 2019-11-12 Tendyne Holdings, Inc. Apparatus and methods for anterior valve leaflet management
JP7081749B2 (en) 2016-05-13 2022-06-07 イエナバルブ テクノロジー インク Heart valve prosthesis delivery system
US10583005B2 (en) 2016-05-13 2020-03-10 Boston Scientific Scimed, Inc. Medical device handle
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
WO2017218375A1 (en) 2016-06-13 2017-12-21 Tendyne Holdings, Inc. Sequential delivery of two-part prosthetic mitral valve
US11090157B2 (en) 2016-06-30 2021-08-17 Tendyne Holdings, Inc. Prosthetic heart valves and apparatus and methods for delivery of same
US10856981B2 (en) 2016-07-08 2020-12-08 Edwards Lifesciences Corporation Expandable sheath and methods of using the same
EP3484411A1 (en) 2016-07-12 2019-05-22 Tendyne Holdings, Inc. Apparatus and methods for trans-septal retrieval of prosthetic heart valves
US11096781B2 (en) 2016-08-01 2021-08-24 Edwards Lifesciences Corporation Prosthetic heart valve
US10357361B2 (en) 2016-09-15 2019-07-23 Edwards Lifesciences Corporation Heart valve pinch devices and delivery systems
US10463484B2 (en) 2016-11-17 2019-11-05 Edwards Lifesciences Corporation Prosthetic heart valve having leaflet inflow below frame
US10973631B2 (en) 2016-11-17 2021-04-13 Edwards Lifesciences Corporation Crimping accessory device for a prosthetic valve
US10603165B2 (en) 2016-12-06 2020-03-31 Edwards Lifesciences Corporation Mechanically expanding heart valve and delivery apparatus therefor
JP7440263B2 (en) 2016-12-16 2024-02-28 エドワーズ ライフサイエンシーズ コーポレイション Deployment systems, tools, and methods for delivering anchoring devices for prosthetic valves
WO2018118717A1 (en) 2016-12-20 2018-06-28 Edwards Lifesciences Corporation Systems and mechanisms for deploying a docking device for a replacement heart valve
US11013600B2 (en) 2017-01-23 2021-05-25 Edwards Lifesciences Corporation Covered prosthetic heart valve
US11185406B2 (en) 2017-01-23 2021-11-30 Edwards Lifesciences Corporation Covered prosthetic heart valve
US11654023B2 (en) 2017-01-23 2023-05-23 Edwards Lifesciences Corporation Covered prosthetic heart valve
US10987495B2 (en) * 2017-01-25 2021-04-27 C.R. Bard, Inc. Inflatable medical balloon with variable profile
CN110392557A (en) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 Heart valve simulation
US11224511B2 (en) 2017-04-18 2022-01-18 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
HRP20220104T1 (en) 2017-04-18 2022-04-15 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
US10973634B2 (en) 2017-04-26 2021-04-13 Edwards Lifesciences Corporation Delivery apparatus for a prosthetic heart valve
US10959846B2 (en) 2017-05-10 2021-03-30 Edwards Lifesciences Corporation Mitral valve spacer device
US10842619B2 (en) 2017-05-12 2020-11-24 Edwards Lifesciences Corporation Prosthetic heart valve docking assembly
US11135056B2 (en) 2017-05-15 2021-10-05 Edwards Lifesciences Corporation Devices and methods of commissure formation for prosthetic heart valve
EP4427706A2 (en) 2017-05-22 2024-09-11 Edwards Lifesciences Corporation Valve anchor and installation method
US12064341B2 (en) 2017-05-31 2024-08-20 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10869759B2 (en) 2017-06-05 2020-12-22 Edwards Lifesciences Corporation Mechanically expandable heart valve
US11026785B2 (en) 2017-06-05 2021-06-08 Edwards Lifesciences Corporation Mechanically expandable heart valve
US10828154B2 (en) 2017-06-08 2020-11-10 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
US10639152B2 (en) 2017-06-21 2020-05-05 Edwards Lifesciences Corporation Expandable sheath and methods of using the same
CA3068313A1 (en) 2017-06-30 2019-01-03 Edwards Lifesciences Corporation Docking stations for transcatheter valves
WO2019006332A1 (en) 2017-06-30 2019-01-03 Edwards Lifesciences Corporation Lock and release mechanisms for trans-catheter implantable devices
US10857334B2 (en) 2017-07-12 2020-12-08 Edwards Lifesciences Corporation Reduced operation force inflator
US11154399B2 (en) 2017-07-13 2021-10-26 Tendyne Holdings, Inc. Prosthetic heart valves and apparatus and methods for delivery of same
US10918473B2 (en) 2017-07-18 2021-02-16 Edwards Lifesciences Corporation Transcatheter heart valve storage container and crimping mechanism
CN111163729B (en) 2017-08-01 2022-03-29 波士顿科学国际有限公司 Medical implant locking mechanism
EP3664749B1 (en) 2017-08-11 2023-07-26 Edwards Lifesciences Corporation Sealing element for prosthetic heart valve
US11083575B2 (en) 2017-08-14 2021-08-10 Edwards Lifesciences Corporation Heart valve frame design with non-uniform struts
US10932903B2 (en) 2017-08-15 2021-03-02 Edwards Lifesciences Corporation Skirt assembly for implantable prosthetic valve
CN111225633B (en) 2017-08-16 2022-05-31 波士顿科学国际有限公司 Replacement heart valve coaptation assembly
US10898319B2 (en) 2017-08-17 2021-01-26 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10973628B2 (en) 2017-08-18 2021-04-13 Edwards Lifesciences Corporation Pericardial sealing member for prosthetic heart valve
US10722353B2 (en) 2017-08-21 2020-07-28 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US10806573B2 (en) 2017-08-22 2020-10-20 Edwards Lifesciences Corporation Gear drive mechanism for heart valve delivery apparatus
EP3675774B1 (en) 2017-08-28 2023-06-21 Tendyne Holdings, Inc. Prosthetic heart valves with tether coupling features
US11051939B2 (en) 2017-08-31 2021-07-06 Edwards Lifesciences Corporation Active introducer sheath system
US10973629B2 (en) 2017-09-06 2021-04-13 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
US11147667B2 (en) 2017-09-08 2021-10-19 Edwards Lifesciences Corporation Sealing member for prosthetic heart valve
IL273562B2 (en) 2017-10-18 2024-01-01 Edwards Lifesciences Corp Catheter assembly
US11207499B2 (en) 2017-10-20 2021-12-28 Edwards Lifesciences Corporation Steerable catheter
EP3740160A2 (en) 2018-01-19 2020-11-25 Boston Scientific Scimed Inc. Inductance mode deployment sensors for transcatheter valve system
US11246625B2 (en) 2018-01-19 2022-02-15 Boston Scientific Scimed, Inc. Medical device delivery system with feedback loop
WO2019157156A1 (en) 2018-02-07 2019-08-15 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
EP3758651B1 (en) 2018-02-26 2022-12-07 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
US11318011B2 (en) 2018-04-27 2022-05-03 Edwards Lifesciences Corporation Mechanically expandable heart valve with leaflet clamps
US11229517B2 (en) 2018-05-15 2022-01-25 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11844914B2 (en) 2018-06-05 2023-12-19 Edwards Lifesciences Corporation Removable volume indicator for syringe
WO2019241477A1 (en) 2018-06-13 2019-12-19 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
US20210282950A1 (en) * 2018-07-05 2021-09-16 Board Of Regents Of The University Of Nebraska Automatically deployable intravascular device system
US11090467B2 (en) 2018-10-02 2021-08-17 Alucent Biomedical, Inc. Apparatus and methods for scaffolding
CN112867468B (en) 2018-10-19 2024-08-23 爱德华兹生命科学公司 Prosthetic heart valve with non-cylindrical frame
US11779728B2 (en) 2018-11-01 2023-10-10 Edwards Lifesciences Corporation Introducer sheath with expandable introducer
WO2020123486A1 (en) 2018-12-10 2020-06-18 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
JP2022517423A (en) 2019-01-17 2022-03-08 エドワーズ ライフサイエンシーズ コーポレイション Frame for artificial valve
WO2020198273A2 (en) 2019-03-26 2020-10-01 Edwards Lifesciences Corporation Prosthetic heart valve
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading
US11426298B2 (en) * 2019-07-31 2022-08-30 Alucent Biomedical, Inc. Apparatus and methods for restoring tissue
EP3831343B1 (en) 2019-12-05 2024-01-31 Tendyne Holdings, Inc. Braided anchor for mitral valve
US11648114B2 (en) 2019-12-20 2023-05-16 Tendyne Holdings, Inc. Distally loaded sheath and loading funnel
US11951002B2 (en) 2020-03-30 2024-04-09 Tendyne Holdings, Inc. Apparatus and methods for valve and tether fixation
EP4167911A1 (en) 2020-06-18 2023-04-26 Edwards Lifesciences Corporation Crimping methods
US11678980B2 (en) 2020-08-19 2023-06-20 Tendyne Holdings, Inc. Fully-transseptal apical pad with pulley for tensioning
KR20230073211A (en) 2020-08-24 2023-05-25 에드워즈 라이프사이언시스 코포레이션 Natural valve commissure and prosthetic heart valve commissure alignment method and system
CN216455494U (en) 2020-08-31 2022-05-10 爱德华兹生命科学公司 System for crimping a prosthetic implant to a delivery device and crimping system
KR20230132822A (en) 2021-01-20 2023-09-18 에드워즈 라이프사이언시스 코포레이션 Connecting skirt for attaching valve leaflets to the frame of an artificial heart valve
EP4312883A1 (en) 2021-03-23 2024-02-07 Edwards Lifesciences Corporation Prosthetic heart valve having elongated sealing member
CN117045941A (en) * 2022-05-05 2023-11-14 上海臻亿医疗科技有限公司 Balloon catheter device and system for dilating an aortic valve

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439446A (en) * 1994-06-30 1995-08-08 Boston Scientific Corporation Stent and therapeutic delivery system
US5514092A (en) * 1994-08-08 1996-05-07 Schneider (Usa) Inc. Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK238080A (en) * 1980-06-03 1981-12-04 P Pless GIANT STIMULATION PROBLEMS FOR ELECTRIC STIMULATION OF THE HEART
US4423725A (en) * 1982-03-31 1984-01-03 Baran Ostap E Multiple surgical cuff
US4546759A (en) * 1983-07-29 1985-10-15 Mladen Solar Method and apparatus for assisting human heart function
US5019075A (en) * 1984-10-24 1991-05-28 The Beth Israel Hospital Method and apparatus for angioplasty
US4824436A (en) * 1985-04-09 1989-04-25 Harvey Wolinsky Method for the prevention of restenosis
AT385894B (en) * 1985-10-04 1988-05-25 Basem Dr Nashef TUBULAR PROBE
US4681564A (en) * 1985-10-21 1987-07-21 Landreneau Michael D Catheter assembly having balloon extended flow path
US4878492A (en) * 1987-10-08 1989-11-07 C. R. Bard, Inc. Laser balloon catheter
AU4191989A (en) * 1988-08-24 1990-03-23 Marvin J. Slepian Biodegradable polymeric endoluminal sealing
US4968307A (en) * 1989-01-09 1990-11-06 Advanced Cardiovascular Systems, Inc. Catheter for uniform distribution of therapeutic fluids
US5021044A (en) * 1989-01-30 1991-06-04 Advanced Cardiovascular Systems, Inc. Catheter for even distribution of therapeutic fluids
US5056532A (en) * 1989-07-25 1991-10-15 Medtronic, Inc. Esophageal pacing lead
US5236413B1 (en) * 1990-05-07 1996-06-18 Andrew J Feiring Method and apparatus for inducing the permeation of medication into internal tissue
ATE123658T1 (en) * 1990-06-15 1995-06-15 Cortrak Medical Inc DEVICE FOR DISPENSING MEDICATIONS.
US5498238A (en) * 1990-06-15 1996-03-12 Cortrak Medical, Inc. Simultaneous angioplasty and phoretic drug delivery
US5087243A (en) * 1990-06-18 1992-02-11 Boaz Avitall Myocardial iontophoresis
US5279546A (en) * 1990-06-27 1994-01-18 Lake Region Manufacturing Company, Inc. Thrombolysis catheter system
US5169395A (en) * 1991-04-26 1992-12-08 Pdt Cardiovascular, Inc. Laser delivery system
US5360440A (en) * 1992-03-09 1994-11-01 Boston Scientific Corporation In situ apparatus for generating an electrical current in a biological environment
US5383928A (en) * 1992-06-10 1995-01-24 Emory University Stent sheath for local drug delivery
US5507724A (en) * 1992-07-01 1996-04-16 Genetronics, Inc. Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells
US5298018A (en) * 1992-08-14 1994-03-29 Pdt Cardiovascular, Inc. Method for treating cardiovascular disease through adjunctive photodynamic therapy
US5368034A (en) * 1992-09-04 1994-11-29 Boston Scientific Corporation Method and apparatus for thrombolytic therapy
US5256141A (en) * 1992-12-22 1993-10-26 Nelson Gencheff Biological material deployment method and apparatus
US5417653A (en) * 1993-01-21 1995-05-23 Sahota; Harvinder Method for minimizing restenosis
US5315992A (en) * 1993-03-10 1994-05-31 Dalton William J Triple cuff endobronchial tube with selective multiple outlets served by a single airflow passage
US5405322A (en) * 1993-08-12 1995-04-11 Boston Scientific Corporation Method for treating aneurysms with a thermal source
US5380299A (en) * 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
US5454794A (en) * 1993-10-15 1995-10-03 Pdt Systems, Inc. Steerable light diffusing catheter
EP0754074A4 (en) * 1994-04-01 1998-05-06 Localmed Inc Method and apparatus for performing multiple procedures
US5484412A (en) * 1994-04-19 1996-01-16 Pierpont; Brien E. Angioplasty method and means for performing angioplasty
US5505700A (en) * 1994-06-14 1996-04-09 Cordis Corporation Electro-osmotic infusion catheter

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439446A (en) * 1994-06-30 1995-08-08 Boston Scientific Corporation Stent and therapeutic delivery system
US5514092A (en) * 1994-08-08 1996-05-07 Schneider (Usa) Inc. Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0935479A4 *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006096A1 (en) * 1997-07-30 1999-02-11 Johannes Rieger Balloon dilatation catheter
EP0920882A3 (en) * 1997-12-04 2000-01-05 Schneider Inc. Balloon dilatation-drug delivery catheter and stent deployment-drug delivery catheter in rapid exchange configuration
US6231588B1 (en) 1998-08-04 2001-05-15 Percusurge, Inc. Low profile catheter for angioplasty and occlusion
US6558401B1 (en) 1998-08-04 2003-05-06 Medtronic Percusurge, Inc. Low profile catheter for angioplasty and occlusion
GR1003402B (en) * 1999-02-03 2000-07-11 Catheter for protected angioplastic operation on the artery branch
JP2005516655A (en) * 2002-02-01 2005-06-09 ロバート,ジェー. ゴールドマン Multifunctional catheter and method of use thereof
EP1469902A2 (en) * 2002-02-01 2004-10-27 Robert J. Goldman Multi-function catheter and use thereof
EP1469902A4 (en) * 2002-02-01 2006-08-23 Robert J Goldman Multi-function catheter and use thereof
US7645259B2 (en) 2002-02-01 2010-01-12 Vascular Designs, Inc. Multi-function catheter and use thereof
US8062251B2 (en) 2002-02-01 2011-11-22 Vascular Designs, Inc. Multi-function catheter and use thereof
US8251948B2 (en) 2002-02-01 2012-08-28 Vascular Designs, Inc. Multi-function catheter and use thereof
WO2004012589A3 (en) * 2002-08-05 2004-07-15 Miravant Medical Technologies Catheter for diagnosis and treatment of diseased vessels
WO2004012589A2 (en) * 2002-08-05 2004-02-12 Miravant Medical Technologies, Inc. Catheter for diagnosis and treatment of diseased vessels
US7396354B2 (en) 2002-08-05 2008-07-08 Rychnovsky Steven J Light delivery catheter
WO2010011602A1 (en) * 2008-07-23 2010-01-28 Boston Scientific Scimed, Inc. Occlusion crossing device and method
US8109985B2 (en) 2008-07-23 2012-02-07 Boston Scientific Scimed, Inc. Occlusion crossing device and method
US9427557B2 (en) 2008-07-23 2016-08-30 Boston Scientific Scimed, Inc. Occlusion crossing device and method
EP3932340A1 (en) * 2020-06-29 2022-01-05 Neuravi Limited Isolated stenting with distal balloon

Also Published As

Publication number Publication date
DE69633410T2 (en) 2005-10-27
EP0935479A1 (en) 1999-08-18
US5728068A (en) 1998-03-17
EP0935479B1 (en) 2004-09-15
EP0935479A4 (en) 2000-04-26
DE69633410D1 (en) 2004-10-21

Similar Documents

Publication Publication Date Title
EP0935479B1 (en) Multipurpose balloon catheter
US6893437B2 (en) Microporous electrode structure and method of making the same
US6389314B2 (en) Method and apparatus for inducing the permeation of medication into internal tissue
US6016437A (en) Catheter probe system with inflatable soft shafts
EP1140279B1 (en) Temporary atrial cardioversion electrode catheter
US6068653A (en) Electrophysiology catheter device
US5891027A (en) Cardiovascular catheter system with an inflatable soft tip
US5697965A (en) Method of making an atrial defibrillation catheter
US6148222A (en) Esophageal catheters and method of use
US5676693A (en) Electrophysiology device
EP0428279B1 (en) Braid electrode leads and catheters for using the same
US5403351A (en) Method of transvenous defibrillation/cardioversion employing an endocardial lead system
US5423865A (en) Electrode system for a defibrillator
USRE39200E1 (en) Apparatus for treating a blood vessel
CA2197350A1 (en) Polymer matrix drug delivery apparatus and method
GR3034385T3 (en) Implantable catheter and method of use
CN113842190A (en) Electrode balloon catheter
CN114831697A (en) Shock wave generating device for molding internal cavity
ES2859158T3 (en) Implantable electrical multipolar connection structure
CN115697464A (en) Medical device for electroporation
CN216167694U (en) Electrode balloon catheter
CA2241176C (en) Multipurpose balloon catheter
WO2023238030A1 (en) Blood vessel spasm relief device
WO2024163785A1 (en) Intravascular lithotripsy catheter with movable emitters

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA DE GB JP MX US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2241176

Country of ref document: CA

Ref country code: CA

Ref document number: 2241176

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1996945449

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

Ref document number: 97524620

Format of ref document f/p: F

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 1996945449

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 1996945449

Country of ref document: EP