WO1995033049A3 - FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS - Google Patents

FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS Download PDF

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Publication number
WO1995033049A3
WO1995033049A3 PCT/FR1995/000701 FR9500701W WO9533049A3 WO 1995033049 A3 WO1995033049 A3 WO 1995033049A3 FR 9500701 W FR9500701 W FR 9500701W WO 9533049 A3 WO9533049 A3 WO 9533049A3
Authority
WO
WIPO (PCT)
Prior art keywords
tbp2
neisseria meningitidis
fragments
transferrine
receptor
Prior art date
Application number
PCT/FR1995/000701
Other languages
English (en)
Other versions
WO1995033049A2 (fr
Inventor
Marie-Jose Bernadette J Millet
Ling Lissolo
Veronique Mazarin
Michele Legrain
Eric Jacobs
Original Assignee
Pasteur Merieux Serums Vacc
Transgene Sa
Millet Marie Jose Bernadette J
Ling Lissolo
Veronique Mazarin
Michele Legrain
Eric Jacobs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serums Vacc, Transgene Sa, Millet Marie Jose Bernadette J, Ling Lissolo, Veronique Mazarin, Michele Legrain, Eric Jacobs filed Critical Pasteur Merieux Serums Vacc
Priority to EP95921860A priority Critical patent/EP0720653A1/fr
Priority to JP8500434A priority patent/JPH09501059A/ja
Priority to AU26757/95A priority patent/AU706090B2/en
Priority to HU9600210A priority patent/HU220116B/hu
Publication of WO1995033049A2 publication Critical patent/WO1995033049A2/fr
Publication of WO1995033049A3 publication Critical patent/WO1995033049A3/fr
Priority to NO960332A priority patent/NO960332L/no
Priority to FI960428A priority patent/FI960428A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

L'invention a pour objet un polypeptide ayant une séquence d'acides aminés qui dérive de celle de la sous-unité Tbp2 du récepteur transferrine d'une souche de Neisseria meningitidis de type IM2169 ou IM2394 dont les premier, deuxième et troisième domaines sont définis par alignement au maximum d'homologie, sur la séquence de la sous-unité Tbp2 de la souche de référence respective, IM2169 ou IM2394, notamment par délétion totale ou partielle d'au moins un domaine de ladite sous-unité Tbp2 de type IM2169 ou IM2394, à condition que le premier et le deuxième domaine ne soient pas simultanément et totalement délétés.
PCT/FR1995/000701 1994-05-31 1995-05-30 FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS WO1995033049A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP95921860A EP0720653A1 (fr) 1994-05-31 1995-05-30 FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS
JP8500434A JPH09501059A (ja) 1994-05-31 1995-05-30 髄膜炎菌のトランスフェリン受容体のＴｂｐ２断片
AU26757/95A AU706090B2 (en) 1994-05-31 1995-05-30 Tbp2 fragments of the transferrine receptor of neisseria meningitidis
HU9600210A HU220116B (hu) 1994-05-31 1995-05-30 A Neisseria meningitidis transzferin-receptorának Tbp2-fragmentumai
NO960332A NO960332L (no) 1994-05-31 1996-01-26 Tbp2 fragmenter av transferrinreseptoren av neisseria meningitidis
FI960428A FI960428A (fi) 1994-05-31 1996-01-30 Meningokokin reseptoritransferriinin Tbp2-osia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9406594A FR2720408B1 (fr) 1994-05-31 1994-05-31 Fragments Tbp2 de Neisseria meningitidis.
FR94/06594 1994-05-31

Publications (2)

Publication Number Publication Date
WO1995033049A2 WO1995033049A2 (fr) 1995-12-07
WO1995033049A3 true WO1995033049A3 (fr) 1996-01-04

Family

ID=9463680

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1995/000701 WO1995033049A2 (fr) 1994-05-31 1995-05-30 FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS

Country Status (9)

Country Link
EP (1) EP0720653A1 (fr)
JP (1) JPH09501059A (fr)
AU (1) AU706090B2 (fr)
CA (1) CA2167936A1 (fr)
FI (1) FI960428A (fr)
FR (1) FR2720408B1 (fr)
HU (1) HU220116B (fr)
NO (1) NO960332L (fr)
WO (1) WO1995033049A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2739624B1 (fr) * 1995-10-10 1997-12-05 Pasteur Merieux Serums Vacc Nouvelle sous-unite tbp2 de neisseria meningitidis
US6440701B1 (en) 1996-03-08 2002-08-27 Aventis Pasteur Limited Transferrin receptor genes of Moraxella
US6090576A (en) * 1996-03-08 2000-07-18 Connaught Laboratories Limited DNA encoding a transferrin receptor of Moraxella
FR2767060B1 (fr) * 1997-08-07 2000-02-11 Pasteur Merieux Serums Vacc Vaccin meningocoque comportant la valence de souche bz83
AU744733B2 (en) * 1997-08-15 2002-02-28 Technology Foundation (Technologiestichting Stw) Neisseria lactoferrin binding protein
EP2210945B1 (fr) 1998-01-14 2013-06-26 Novartis Vaccines and Diagnostics S.r.l. Antigènes de Neisseria meningitidis
NZ508366A (en) 1998-05-01 2004-03-26 Chiron Corp Neisseria meningitidis antigens and compositions
FR2785293B1 (fr) * 1998-10-30 2002-07-05 Pasteur Merieux Serums Vacc Acides nucleiques et polypeptides specifiques des souches pathogenes du genre neisseria
US6391316B1 (en) 1999-03-10 2002-05-21 University Of Saskatchewan Vaccine compositions comprising Haemophilus somnus transferrin-binding proteins and methods of use
US7241449B1 (en) 1999-04-12 2007-07-10 Aventis Pasteur Limited Transferrin receptor genes of moraxella
US7368261B1 (en) 1999-04-30 2008-05-06 Novartis Vaccines And Diagnostics Srl Conserved Neisserial antigens
DK2270173T3 (en) 1999-05-19 2016-03-07 Glaxosmithkline Biolog Sa Neisserial combination compositions
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
CN1800385B (zh) * 2000-02-28 2010-06-02 启龙有限公司 奈瑟球菌蛋白质的异源表达
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
ES2608048T3 (es) 2002-10-11 2017-04-05 Glaxosmithkline Biologicals Sa Vacunas polipeptídicas para protección amplia contra linajes meningocócicos hipervirulentos
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
AU2011300418B2 (en) 2010-09-10 2016-05-12 Glaxosmithkline Biologicals Sa Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
NZ630133A (en) 2012-06-14 2016-10-28 Novartis Ag Vaccines for serogroup x meningococcus

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007172A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. Vaccin de sous-unite contre les infections a neisseriameningitidis et sous-unites correspondantes a l'etat purifie
WO1993006861A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. VACCIN CONTRE LES INFECTIONS A $i(NEISSERIA MENINGITIDIS)
FR2692592A1 (fr) * 1992-06-19 1993-12-24 Pasteur Merieux Serums Vacc Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
WO1994005703A1 (fr) * 1992-08-31 1994-03-17 Global Tek, Inc. Anticorps monoclonal contre la proteine de la bacterie neisseria meningitidis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993007172A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. Vaccin de sous-unite contre les infections a neisseriameningitidis et sous-unites correspondantes a l'etat purifie
WO1993006861A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. VACCIN CONTRE LES INFECTIONS A $i(NEISSERIA MENINGITIDIS)
FR2692592A1 (fr) * 1992-06-19 1993-12-24 Pasteur Merieux Serums Vacc Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
WO1994005703A1 (fr) * 1992-08-31 1994-03-17 Global Tek, Inc. Anticorps monoclonal contre la proteine de la bacterie neisseria meningitidis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEGRAIN, M. ET AL.;: "Cloning and characterization of Neisseria meneingitidis genes encoding the transferrin-binding proteins Tbp1 and Tbp2", GENE, vol. 130, AMSTERDAM NL, pages 73 - 80 *
STEVENSON, P. ET AL.;: "Common antigenic domains in Transferrin-Binding protein 2 of Neisseria meningitidis, Neisseria gonorrhoeae and Haemphilus influenzae Type b", INFECTION AND IMMUNITY, vol. 60, no. 6, WASHINGTON US, pages 2391 - 2396 *

Also Published As

Publication number Publication date
NO960332D0 (no) 1996-01-26
AU2675795A (en) 1995-12-21
WO1995033049A2 (fr) 1995-12-07
EP0720653A1 (fr) 1996-07-10
CA2167936A1 (fr) 1995-12-07
FI960428A0 (fi) 1996-01-30
FR2720408B1 (fr) 1996-08-14
JPH09501059A (ja) 1997-02-04
NO960332L (no) 1996-03-21
HUT75992A (en) 1997-05-28
FI960428A (fi) 1996-03-28
AU706090B2 (en) 1999-06-10
HU220116B (hu) 2001-11-28
FR2720408A1 (fr) 1995-12-01

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