WO1993024234A3 - Apparatus for culturing and detecting bacteria in human tissue - Google Patents

Apparatus for culturing and detecting bacteria in human tissue Download PDF

Info

Publication number
WO1993024234A3
WO1993024234A3 PCT/US1993/005233 US9305233W WO9324234A3 WO 1993024234 A3 WO1993024234 A3 WO 1993024234A3 US 9305233 W US9305233 W US 9305233W WO 9324234 A3 WO9324234 A3 WO 9324234A3
Authority
WO
WIPO (PCT)
Prior art keywords
instrument
racks
drawers
specimen
culturing
Prior art date
Application number
PCT/US1993/005233
Other languages
French (fr)
Other versions
WO1993024234A2 (en
Inventor
Mitchell E Levinson
Gary P Brown
Donald Lichtenstein
Roger J Morris
Original Assignee
Baxter Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Diagnostics Inc filed Critical Baxter Diagnostics Inc
Priority to EP93914318A priority Critical patent/EP0596102A1/en
Priority to JP6500850A priority patent/JPH06509720A/en
Priority to AU44024/93A priority patent/AU662065B2/en
Publication of WO1993024234A2 publication Critical patent/WO1993024234A2/en
Publication of WO1993024234A3 publication Critical patent/WO1993024234A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/14—Incubators; Climatic chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/02—Water baths; Sand baths; Air baths
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/48—Holding appliances; Racks; Supports
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G01N21/783—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour for analysing gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G01N21/80—Indicating pH value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0496—Other details
    • G01N2035/0498—Drawers used as storage or dispensing means for vessels or cuvettes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Plasma & Fusion (AREA)
  • Computer Hardware Design (AREA)
  • Thermal Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

An instrument for culturing and detecting the presence of microorganisms in human tissue specimens is disclosed. The instrument includes one or more drawers slidably received within the instrument housing. The drawers include racks for holding and agitating a plurality of specimen containing bottles. The instrument may include a mechanical drive apparatus designed to move the racks in a substantially sinusoidal pattern of motion. The racks are preferably provided with gripping means for removably and repeatably positioning the bottles within the drawer. An optical detection system is also disclosed, in which an optical filter is used to render a photodetector substantially blind to all light other than light emitted by a fluorescent sensor located within the specimen vessel, including excitation light impinging on the sensor. The instrument preferably includes a forced air convection system for warming the interior of the drawers and the specimen vessels held therein.
PCT/US1993/005233 1992-05-22 1993-05-24 Apparatus for culturing and detecting bacteria in human tissue WO1993024234A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP93914318A EP0596102A1 (en) 1992-05-22 1993-05-24 Apparatus for culturing and detecting bacteria in human tissue
JP6500850A JPH06509720A (en) 1992-05-22 1993-05-24 Device for culturing and detecting bacteria in human tissues
AU44024/93A AU662065B2 (en) 1992-05-22 1993-05-24 Apparatus for culturing and detecting bacteria in human tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88762792A 1992-05-22 1992-05-22
US07/887,627 1992-05-22

Publications (2)

Publication Number Publication Date
WO1993024234A2 WO1993024234A2 (en) 1993-12-09
WO1993024234A3 true WO1993024234A3 (en) 1994-03-31

Family

ID=25391542

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/005233 WO1993024234A2 (en) 1992-05-22 1993-05-24 Apparatus for culturing and detecting bacteria in human tissue

Country Status (5)

Country Link
EP (1) EP0596102A1 (en)
JP (1) JPH06509720A (en)
AU (1) AU662065B2 (en)
CA (1) CA2113550A1 (en)
WO (1) WO1993024234A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105087349A (en) * 2014-04-17 2015-11-25 湖南长沙天地人生物科技有限公司 Drawer guide buffer mechanism

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07508892A (en) * 1993-05-14 1995-10-05 マイクロスキャン、インコーポレイテッド Improved optical detection system for devices culturing and detecting bacteria in human tissues
US5498543A (en) * 1994-06-07 1996-03-12 Becton Dickinson And Company Sub-compact blood culture apparatus
JP4751566B2 (en) * 2002-04-09 2011-08-17 オリンパス株式会社 Cell culture system, cultured cell verification device, and cell culture device
DE10325474B4 (en) * 2003-07-23 2005-08-18 RATIONAL Technische Lösungen GmbH Roller carriage drive
US8871497B2 (en) * 2008-01-14 2014-10-28 Board Of Regents Of The University Of Nebraska Device and method for automating microbiology processes
CN105491887B (en) * 2013-07-05 2018-01-19 瑞文特国际有限公司 Steam generating system
JP5925975B2 (en) 2013-12-04 2016-05-25 パナソニックヘルスケアホールディングス株式会社 Incubator transport system, incubator storage, isolator system
BE1024593B1 (en) * 2016-12-29 2018-04-12 Microtechnix Bvba Device and method for automatically measuring biological samples
EP3388840B1 (en) * 2017-04-10 2020-02-12 Roche Diagnostics GmbH Drawer assembly for a laboratory instrument
CN108732135A (en) * 2017-11-20 2018-11-02 重庆中元汇吉生物技术有限公司 A kind of blood cell and analysis of protein device
CN109022267B (en) * 2018-09-05 2024-03-12 浙江省计量科学研究院 Automatic sterile observation incubator for biological culture
RU2695889C1 (en) * 2018-11-13 2019-07-29 Общество с ограниченной ответственностью "ИФАТОНИКА" Device for determining characteristics of gas and liquid samples

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2528152A1 (en) * 1975-06-24 1977-01-20 Ratiomed Gmbh Rack for carrying laboratory samples - having board with holes and support below between two end stays in frame
EP0104463A1 (en) * 1982-08-31 1984-04-04 Becton Dickinson and Company Detection of the presence of biological activity utilizing infrared analysis
US4689303A (en) * 1986-02-26 1987-08-25 Kvm Engineering, Inc. Controlled circulation incubator
EP0333253A2 (en) * 1988-03-15 1989-09-20 Akzo Nobel N.V. Apparatus and device for detecting microorganisms
EP0429030A2 (en) * 1989-11-21 1991-05-29 BEHRINGWERKE Aktiengesellschaft Incubator for microtitration plates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3938121A1 (en) * 1989-11-16 1991-05-23 Basf Ag METHOD FOR SEPARATING (ALPHA) -BUTYROLACTONE FROM MIXTURES CONTAINING AMBER OF ACID ETHYL ETHER

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2528152A1 (en) * 1975-06-24 1977-01-20 Ratiomed Gmbh Rack for carrying laboratory samples - having board with holes and support below between two end stays in frame
EP0104463A1 (en) * 1982-08-31 1984-04-04 Becton Dickinson and Company Detection of the presence of biological activity utilizing infrared analysis
US4689303A (en) * 1986-02-26 1987-08-25 Kvm Engineering, Inc. Controlled circulation incubator
EP0333253A2 (en) * 1988-03-15 1989-09-20 Akzo Nobel N.V. Apparatus and device for detecting microorganisms
EP0429030A2 (en) * 1989-11-21 1991-05-29 BEHRINGWERKE Aktiengesellschaft Incubator for microtitration plates

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105087349A (en) * 2014-04-17 2015-11-25 湖南长沙天地人生物科技有限公司 Drawer guide buffer mechanism
CN105087349B (en) * 2014-04-17 2017-09-01 湖南长沙天地人生物科技有限公司 A kind of drawer guide buffer gear

Also Published As

Publication number Publication date
WO1993024234A2 (en) 1993-12-09
EP0596102A1 (en) 1994-05-11
AU662065B2 (en) 1995-08-17
JPH06509720A (en) 1994-11-02
CA2113550A1 (en) 1993-12-09
AU4402493A (en) 1993-12-30

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