WO1994026874A3 - Improved optical detection system for apparatus to culture and detect bacteria in human tissue - Google Patents

Improved optical detection system for apparatus to culture and detect bacteria in human tissue Download PDF

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Publication number
WO1994026874A3
WO1994026874A3 PCT/US1994/005392 US9405392W WO9426874A3 WO 1994026874 A3 WO1994026874 A3 WO 1994026874A3 US 9405392 W US9405392 W US 9405392W WO 9426874 A3 WO9426874 A3 WO 9426874A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection system
improved optical
human tissue
culture
optical detection
Prior art date
Application number
PCT/US1994/005392
Other languages
French (fr)
Other versions
WO1994026874A2 (en
Inventor
Gregory Williams
Gary Brown
Craig Daniel
Carolyn Olson
William Gardner
Glenn Enscoe
Elizabeth Jarrard
Original Assignee
Baxter Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Diagnostics Inc filed Critical Baxter Diagnostics Inc
Priority to JP6525745A priority Critical patent/JPH07508892A/en
Priority to AU70182/94A priority patent/AU7018294A/en
Priority to EP94919140A priority patent/EP0651786A1/en
Priority to CA002138254A priority patent/CA2138254A1/en
Publication of WO1994026874A2 publication Critical patent/WO1994026874A2/en
Publication of WO1994026874A3 publication Critical patent/WO1994026874A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/255—Details, e.g. use of specially adapted sources, lighting or optical systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00524—Mixing by agitating sample carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/04—Batch operation; multisample devices
    • G01N2201/0446—Multicell plate, sequential
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/064—Stray light conditioning

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

An improved optical system for use in an instrument for culturing and detecting the presence of microorganisms in human tissue specimens is disclosed. The improved optical detection system is designed to reduce unwanted noise by substantially blocking all light other than light from a sensor positioned on an inside wall of a culture bottle from reaching the photodetector. A control circuit providing a 'lock-in' detection system designed to reduce unwanted noise is also disclosed. The detection system is capable of rapidly and automatically detecting whether a specimen bottle has been inserted into the instrument.
PCT/US1994/005392 1993-05-14 1994-05-13 Improved optical detection system for apparatus to culture and detect bacteria in human tissue WO1994026874A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP6525745A JPH07508892A (en) 1993-05-14 1994-05-13 Improved optical detection system for devices culturing and detecting bacteria in human tissues
AU70182/94A AU7018294A (en) 1993-05-14 1994-05-13 Improved optical detection system for apparatus to culture and detect bacteria in human tissue
EP94919140A EP0651786A1 (en) 1993-05-14 1994-05-13 Improved optical detection system for apparatus to culture and detect bacteria in human tissue
CA002138254A CA2138254A1 (en) 1993-05-14 1994-05-13 Improved optical detection system for apparatus to culture and detect bacteria in human tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6265993A 1993-05-14 1993-05-14
US08/062,659 1993-05-14

Publications (2)

Publication Number Publication Date
WO1994026874A2 WO1994026874A2 (en) 1994-11-24
WO1994026874A3 true WO1994026874A3 (en) 1995-01-19

Family

ID=22043976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/005392 WO1994026874A2 (en) 1993-05-14 1994-05-13 Improved optical detection system for apparatus to culture and detect bacteria in human tissue

Country Status (5)

Country Link
EP (1) EP0651786A1 (en)
JP (1) JPH07508892A (en)
AU (1) AU7018294A (en)
CA (1) CA2138254A1 (en)
WO (1) WO1994026874A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8911987B2 (en) 2009-05-15 2014-12-16 Biomerieux, Inc System for rapid identification and/or characterization of a microbial agent in a sample
CA2760978C (en) 2009-05-15 2019-10-29 Biomerieux, Inc. Automated loading mechanism for microbial detection apparatus
CN103392006B (en) 2010-07-20 2015-12-16 生物梅里埃有限公司 There is the detector assembly of the flashing lightning magnetic field detector of colorimetric sensor
WO2012016024A2 (en) * 2010-07-29 2012-02-02 Biomerieux, Inc. Culture bottles with internal sensors
US9428287B2 (en) 2012-10-31 2016-08-30 BIOMéRIEUX, INC. Methods of fabricating test sample containers by applying barrier coatings after sealed container sterilization
US9358738B2 (en) 2012-10-31 2016-06-07 Biomerieux, Inc. Aseptic blow, fill and seal methods of fabricating test sample containers and associated systems and containers
US9523110B2 (en) 2013-02-15 2016-12-20 Biomerieux, Inc. Culture containers with internal top coating over gas barrier coating and associated methods
USD737960S1 (en) 2013-04-24 2015-09-01 BIOMéRIEUX, INC. Adapter cap with needle bore having flat internal surfaces
EP2988719B1 (en) 2013-04-24 2017-08-09 bioMérieux, Inc. Adapter caps for sample collection containers and associated molds with core pins and related methods
EP4113101B1 (en) * 2021-06-28 2023-08-09 Metavital GmbH Device performing a radiation measurement of a biological sample in a receptacle-device

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456380A (en) * 1980-08-01 1984-06-26 Fujisawa Pharmaceutical Co., Ltd. Test system for identifying bacteria
DD245491A1 (en) * 1985-12-30 1987-05-06 Akad Wissenschaften Ddr PHASE-SENSITIVE FLUORESCENT DETECTOR FOR SHORT-TERM SPECTROSCOPY
EP0333253A2 (en) * 1988-03-15 1989-09-20 Akzo Nobel N.V. Apparatus and device for detecting microorganisms
EP0448923A1 (en) * 1990-03-29 1991-10-02 Avl Photronics Corporation Method and apparatus for detecting biological activities in a specimen
WO1992008123A1 (en) * 1990-11-05 1992-05-14 Baxter Diagnostics Inc. Measurement of color reactions by monitoring a change of fluorescence
EP0515211A2 (en) * 1991-05-23 1992-11-25 Becton, Dickinson and Company Apparatus and method for phase resolved fluorescence lifetimes of independent and varying amplitude pulses
WO1993024234A2 (en) * 1992-05-22 1993-12-09 Baxter Diagnostics Inc. Apparatus for culturing and detecting bacteria in human tissue

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456380A (en) * 1980-08-01 1984-06-26 Fujisawa Pharmaceutical Co., Ltd. Test system for identifying bacteria
DD245491A1 (en) * 1985-12-30 1987-05-06 Akad Wissenschaften Ddr PHASE-SENSITIVE FLUORESCENT DETECTOR FOR SHORT-TERM SPECTROSCOPY
EP0333253A2 (en) * 1988-03-15 1989-09-20 Akzo Nobel N.V. Apparatus and device for detecting microorganisms
EP0448923A1 (en) * 1990-03-29 1991-10-02 Avl Photronics Corporation Method and apparatus for detecting biological activities in a specimen
WO1992008123A1 (en) * 1990-11-05 1992-05-14 Baxter Diagnostics Inc. Measurement of color reactions by monitoring a change of fluorescence
EP0515211A2 (en) * 1991-05-23 1992-11-25 Becton, Dickinson and Company Apparatus and method for phase resolved fluorescence lifetimes of independent and varying amplitude pulses
WO1993024234A2 (en) * 1992-05-22 1993-12-09 Baxter Diagnostics Inc. Apparatus for culturing and detecting bacteria in human tissue

Also Published As

Publication number Publication date
WO1994026874A2 (en) 1994-11-24
AU7018294A (en) 1994-12-12
CA2138254A1 (en) 1994-11-24
JPH07508892A (en) 1995-10-05
EP0651786A1 (en) 1995-05-10

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