WO1993018059A3 - L-thiazolidine-4-carboxylic acid derivative, processes for the preparation thereof and the use thereof in therapy - Google Patents

L-thiazolidine-4-carboxylic acid derivative, processes for the preparation thereof and the use thereof in therapy Download PDF

Info

Publication number
WO1993018059A3
WO1993018059A3 PCT/EP1993/000451 EP9300451W WO9318059A3 WO 1993018059 A3 WO1993018059 A3 WO 1993018059A3 EP 9300451 W EP9300451 W EP 9300451W WO 9318059 A3 WO9318059 A3 WO 9318059A3
Authority
WO
WIPO (PCT)
Prior art keywords
thiazolidine
processes
preparation
carboxylic acid
therapy
Prior art date
Application number
PCT/EP1993/000451
Other languages
French (fr)
Other versions
WO1993018059A2 (en
Inventor
Stefano Poli
Federico Mailland
Germano Coppi
Giovanni Signorelli
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Priority to AU34992/93A priority Critical patent/AU3499293A/en
Publication of WO1993018059A2 publication Critical patent/WO1993018059A2/en
Publication of WO1993018059A3 publication Critical patent/WO1993018059A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

L-3-[[N-[2-(2-thenoyl)thiopropionyl]glycyl]]thiazolidine-4-carboxylic acid having interesting antielastase, antiemphysema, mucolytic-expectorant, antioxidant (radical-scavenger), antibronchospastic, antitussive, antiinflammatory, hepatoprotecting activities and a low toxicity; the processes for the preparation thereof and pharmaceutical compositions containing it.
PCT/EP1993/000451 1992-03-06 1993-02-26 L-thiazolidine-4-carboxylic acid derivative, processes for the preparation thereof and the use thereof in therapy WO1993018059A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU34992/93A AU3499293A (en) 1992-03-06 1993-02-26 L-thiazolidine-4-carboxylic acid derivative, processes for the preparation thereof and the use thereof in therapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI920525A IT1254514B (en) 1992-03-06 1992-03-06 DERIVATIVE OF L-THIAZOLIDIN-4-CARBOXYLIC ACID, ITS PREPARATION AND THERAPEUTIC USE
ITMI92A000525 1992-03-06

Publications (2)

Publication Number Publication Date
WO1993018059A2 WO1993018059A2 (en) 1993-09-16
WO1993018059A3 true WO1993018059A3 (en) 1993-10-28

Family

ID=11362314

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1993/000451 WO1993018059A2 (en) 1992-03-06 1993-02-26 L-thiazolidine-4-carboxylic acid derivative, processes for the preparation thereof and the use thereof in therapy

Country Status (2)

Country Link
IT (1) IT1254514B (en)
WO (1) WO1993018059A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030046470A (en) * 2000-09-29 2003-06-12 오노 야꾸힝 고교 가부시키가이샤 Airway mucus secretion inhibitors
JP2008050266A (en) * 2006-07-27 2008-03-06 Hitachi Chem Co Ltd Phenol derivative and core crosslinking type star polysulfide obtained from the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0336326A2 (en) * 1988-04-07 1989-10-11 POLI INDUSTRIA CHIMICA S.p.A. 3-Aminodihydrothiophene-2-one peptide derivatives, processes for the preparation and therapeutic use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0336326A2 (en) * 1988-04-07 1989-10-11 POLI INDUSTRIA CHIMICA S.p.A. 3-Aminodihydrothiophene-2-one peptide derivatives, processes for the preparation and therapeutic use

Also Published As

Publication number Publication date
WO1993018059A2 (en) 1993-09-16
ITMI920525A1 (en) 1993-09-06
ITMI920525A0 (en) 1992-03-06
IT1254514B (en) 1995-09-25

Similar Documents

Publication Publication Date Title
AU6194894A (en) Bile acid derivatives, processes for their preparation and the use of these compounds as medicaments
IL147220A0 (en) Indanyl-substituted benzole carbonamide, method for the production of the same, use thereof as a medicament and pharmaceutical preparations containing the same
IL108873A0 (en) 2-debenzoyl-2-acyl taxol derivatives, pharmaceutical compositions containing the same, and methods for the preparation thereof
AU1198699A (en) Novel heterocyclic compounds and their use in medicine, process for their reparation and pharmaceutical compositions containing them
CA2166483A1 (en) New Pharmaceutical Formulation
AU1819088A (en) New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
BG103268A (en) Propionic acid derivatives and their application
HUP0203542A3 (en) 3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
IL174082A0 (en) Crystal modification of a n-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use for the preparation of a pharmaceutical composition
ZA975866B (en) Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases.
AU7640696A (en) Thiazolidinedione derivatives, method for preparing the derivatives and pharmaceutical compositions containing same
AU4299496A (en) Novel multiple-substituent dtpa derivatives and metal complexes thereof, pharmaceutical compositions containing such complexes, their use in diagnosis and therapy, methods ofpreparing the complexing agents and complexes and methods of preparing the pharmaceutical compositions
IL112193A0 (en) Phenylpyrazolopyridine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL111533A0 (en) Quinoxalinedione derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same
IL148870A (en) 2'-substituted 1,1'-biphenyl - 2 - carbonamides, method for the production thereof, use thereof as medicament and pharmaceutical preparations containing said compounds
EP1167354A3 (en) Racemic huperzine A
CA2350659A1 (en) Pharmaceutical composition for modified release insulin sensitiser
AU6242190A (en) New thiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
AU7812794A (en) Pharmaceutical compositions containing n-acetylcarnosine for the treatment of cataract
AU3876293A (en) New heterocyclic compounds, a process for the preparation thereof, and pharmaceutical compositions containing them
MX9709453A (en) Oral pharmaceutical composition of piperidinoalkanol compounds in solution form.
HUP0102609A3 (en) N-phenyl-n'-phenylpropylpiperazine derivatives and process for the preparation thereof, and pharmaceutical compositions containing them
WO1993018059A3 (en) L-thiazolidine-4-carboxylic acid derivative, processes for the preparation thereof and the use thereof in therapy
AU3543797A (en) 1,2-substituted cycloalkane derivatives as thrombine inhibitors, a process for the preparation thereof and the use thereof in pharmaceutical formulations
AU8379091A (en) New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA FI JP KR NO NZ US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

AK Designated states

Kind code of ref document: A3

Designated state(s): AU CA FI JP KR NO NZ US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA