WO1993007250A1 - Nouveau procede et nouvelles compositions pour le nettoyage de la peau et des mains - Google Patents

Nouveau procede et nouvelles compositions pour le nettoyage de la peau et des mains Download PDF

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Publication number
WO1993007250A1
WO1993007250A1 PCT/AU1992/000539 AU9200539W WO9307250A1 WO 1993007250 A1 WO1993007250 A1 WO 1993007250A1 AU 9200539 W AU9200539 W AU 9200539W WO 9307250 A1 WO9307250 A1 WO 9307250A1
Authority
WO
WIPO (PCT)
Prior art keywords
skin
water
composition
composition according
alkanol
Prior art date
Application number
PCT/AU1992/000539
Other languages
English (en)
Inventor
Bruno Anthony Gluck
Original Assignee
Novapharm Research (Australia) Pty. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novapharm Research (Australia) Pty. Ltd. filed Critical Novapharm Research (Australia) Pty. Ltd.
Publication of WO1993007250A1 publication Critical patent/WO1993007250A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2003—Alcohols; Phenols
    • C11D3/2006—Monohydric alcohols
    • C11D3/201—Monohydric alcohols linear
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C11D3/485—Halophors, e.g. iodophors

Definitions

  • the present invention relates to a process for antiseptically cleaning the skin and hands and compositions therefor.
  • antiseptic skin and hand cleansing is effected by treating the hands with an anti-microbial agent dissolved in an alcohol such as ethyl or isopropylalcohol or a mixture thereof at high concentrations, usually 70% v/v, or by scrubbing the hands or skin for 5 minutes with an antibacterial aqueous soap solution.
  • an anti-microbial agent dissolved in an alcohol such as ethyl or isopropylalcohol or a mixture thereof at high concentrations, usually 70% v/v, or by scrubbing the hands or skin for 5 minutes with an antibacterial aqueous soap solution.
  • an antiseptic cleansing composition comprising an alkanol and an aqueous concentrate of a surfactant.
  • a method for cleansing skin comprising applying the composition of this invention onto the skin in a sufficient amount and for a sufficient period of time in order to achieve asepsis.
  • Suitable alkanols are the lower alkanols such as methanol, ethanol, n-propanol or isopropanol. Alkanols might be single or mixtures thereof and should not be less than
  • aromatic alcohols such as benzyl alcohol, phenoxyethyl or - propyl alcohol might be added to a maximum of 5 % calculated on the total volume of the final formulation.
  • the cationic compound may be a quaternary ammonium compound or a bis or di-bis-biguanidine:
  • the composition may also contain a microbiocidal compound which may be any commonly used for disinfection.
  • the microbiocide may be a cationic microbiocide, an iodophor, a bacteriostat or a phenol or derivative thereof.
  • Suitable quaternary ammonium compounds are benzalkonium chloride, benzethonium chloride, methylbenzethonium chloride, hexadecylpyridinium chloride, alkylisoquinolinium bromide or hexadecyltrimethylammonium bromide. Most preferably the quaternary ammonium compound is benzalkonium chloride.
  • a preferred biguanidine is chlorhexidine gluconate.
  • a preferred iodophor is povidone iodine.
  • a preferred bacteriostat is hexachlorophene or triclosan.
  • a preferred phenol is 2-hydroxy diphenyl.
  • Surfactants should preferably be mild to the skin such as the sodium sulfosuccinates, monoethanolamine lauryl ethoxy sulfonates or amphoterics such as dodecyl propylamino acetic acid.
  • the nonionic surfactant may be the ethoxy-derivative of either a fatty alkanol or alkyl phenyl. The alkanol may be present up to 80 parts by volume.
  • the time of application is from a minimum of about 30 to a maximum until most or all of the alkanol has evaporated, but preferably about 90 seconds.
  • compositions of this invention may be used to disinfect the skin.
  • Advantageously foaming agents can be included in the compositions such as the alkyl mono or diethanolamine of oleyl-, coco-, lauryl- or undecylenic acid or thickening agent such as carbopol or hydroxyethyl cellulose.
  • This novel preparation provides a new process of complete hand and skin disinfection by reducing scrubbing time considerably from the standard time of 5 minutes by 2 to 3 minutes without dermatological damage to the skin on repeated applications. This method is particularly applicable to human handwashing.
  • Example 1 The hand wash of Example 1 was evenly applied for 60 seconds on dry hands to 5 cover all parts and a little water added with a routine washing movement of the hands. A copious foam developed similar to washing with soaps. After 30 seconds the hands were
  • compositions of the present invention will find wide use in medical, veterinary, and food processing industries.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne une composition de nettoyage antiseptique comprenant un alcane et un concentré aqueux d'un agent tensio-actif. Les compositions peuvent aussi comprendre un pesticide. La présente invention concerne de plus un procédé pour le nettoyage de la peau comprenant l'application de la composition objet de cette invention sur la peau, permettant à l'alcane de la composition déposé sur la peau de s'évaporer de sorte que la peau soit substantiellement séche, l'application d'une petite quantité d'eau sur la peau pratiquement sèche, le lavage de la peau avec formation de mousse et enfin le rinçage de la peau.
PCT/AU1992/000539 1991-10-09 1992-10-09 Nouveau procede et nouvelles compositions pour le nettoyage de la peau et des mains WO1993007250A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPK8798 1991-10-09
AUPK879891 1991-10-09

Publications (1)

Publication Number Publication Date
WO1993007250A1 true WO1993007250A1 (fr) 1993-04-15

Family

ID=3775737

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AU1992/000539 WO1993007250A1 (fr) 1991-10-09 1992-10-09 Nouveau procede et nouvelles compositions pour le nettoyage de la peau et des mains

Country Status (1)

Country Link
WO (1) WO1993007250A1 (fr)

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0689767A3 (fr) * 1994-06-27 1996-03-27 Becton Dickinson Co Formulations désinfectantes pour la peau
WO1997035475A1 (fr) * 1996-03-27 1997-10-02 Antiseptica Chemisch-Pharmazeutische Produkte Gmbh Agent desinfectant pour les mains
WO1997046218A2 (fr) * 1996-06-04 1997-12-11 Ciba Specialty Chemicals Holding Inc. Formulations liquides concentrees comprenant un principe actif microbicide
US5700842A (en) * 1995-11-01 1997-12-23 Kimberly-Clark Worldwide, Inc. Methods of incorporating a hydrophobic substance into an aqueous solution
WO1998001110A1 (fr) * 1996-07-10 1998-01-15 Calgon Vestal, Inc. Produit de lavage pour la peau a base de triclosan et possedant une meilleure efficacite
EP0882446A1 (fr) * 1997-06-02 1998-12-09 Gojo Industries,Inc. Compositions antimicrobiennes pour le nettoyage de la peau
US5888524A (en) * 1995-11-01 1999-03-30 Kimberly-Clark Worldwide, Inc. Antimicrobial compositions and wet wipes including the same
WO2000048554A2 (fr) * 1999-02-16 2000-08-24 Ecolab Inc. Compositions synergiques antimicrobiennes de nettoyage de la peau
FR2791890A1 (fr) * 1999-04-12 2000-10-13 Gilbert Lab Solution de chlorhexidine alcoolique coloree et sa methode de fabrication
WO2001041567A1 (fr) * 1999-12-13 2001-06-14 Ethicon, Inc. Compositions antimicrobiennes a forte penetration
WO2001064034A1 (fr) * 1999-05-19 2001-09-07 Stack, Kevin Lotion desinfectante antimicrobienne avec des proprietes de protection de la peau
US6531434B1 (en) * 1997-05-20 2003-03-11 Novapharm Research (Australia) Pty. Alkylpolyglucosides containing disinfectant compositions active against pseudomonas microorganism
US6579516B1 (en) 1995-06-13 2003-06-17 Zahra Mansouri Methods of delivering materials into the skin, and compositions used therein
WO2004101725A1 (fr) * 2003-05-15 2004-11-25 Greenbridge Environmental Control Limited Composition de nettoyage antivirale
WO2004101726A3 (fr) * 2003-05-15 2005-03-17 Greenbridge Environmental Cont Preparation nettoyante anti-virale et anti-bacterienne
WO2006062846A2 (fr) * 2004-12-09 2006-06-15 The Dial Corporation Compositions presentant une efficacite antivirale et antibacterienne elevee
WO2006062897A2 (fr) * 2004-12-09 2006-06-15 The Dial Corporation Compositions presentant une efficacite antivirale et antibacterienne elevee
DE102004062775A1 (de) * 2004-12-21 2006-06-29 Stockhausen Gmbh Alkoholischer Pumpschaum
AU2005209647B2 (en) * 1999-12-13 2008-10-02 Ethicon, Inc. Deep penetrating antimicrobial compositions
US7566740B2 (en) * 1998-10-06 2009-07-28 Bml Pharmaceuticals, Inc. Method of treating mucositis
WO2012119644A1 (fr) * 2011-03-08 2012-09-13 Sca Hygiene Products Ab Composition nettoyante antimicrobienne pauvre en alcool

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2927857A (en) * 1957-07-05 1958-01-09 Scottish Oils Limited Germicidal compositions
DD203685A1 (de) * 1982-03-15 1983-11-02 Leuna Werke Veb Wirkstoffkombination zur desinfektion
AU4957185A (en) * 1984-09-26 1986-04-17 Novapharm Research (Australia) Pty Ltd Antiseptic cleansing compositions
JPH01272503A (ja) * 1988-04-22 1989-10-31 Asahi Denka Kogyo Kk 手指殺菌消毒用洗浄剤
AU4557989A (en) * 1988-12-01 1990-06-07 Unilever Plc Topical composition
AU4888890A (en) * 1989-01-31 1990-08-09 Ciba-Geigy Ag Rapid ophthalmic device disinfecting solution and method

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2927857A (en) * 1957-07-05 1958-01-09 Scottish Oils Limited Germicidal compositions
AU57566A (en) * 1965-02-17 1967-07-20 Johnson & Johnson Bactericidal compositions
DD203685A1 (de) * 1982-03-15 1983-11-02 Leuna Werke Veb Wirkstoffkombination zur desinfektion
AU4957185A (en) * 1984-09-26 1986-04-17 Novapharm Research (Australia) Pty Ltd Antiseptic cleansing compositions
JPH01272503A (ja) * 1988-04-22 1989-10-31 Asahi Denka Kogyo Kk 手指殺菌消毒用洗浄剤
AU4557989A (en) * 1988-12-01 1990-06-07 Unilever Plc Topical composition
AU4888890A (en) * 1989-01-31 1990-08-09 Ciba-Geigy Ag Rapid ophthalmic device disinfecting solution and method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN, C-679, page 163; & JP,A,1 272 503, (ASHAHI DENK A KOGYO K K), 31 October 1989. *

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0689767A3 (fr) * 1994-06-27 1996-03-27 Becton Dickinson Co Formulations désinfectantes pour la peau
US7771753B2 (en) 1995-06-13 2010-08-10 Laboratory Skin Care, Inc. Topical formulations comprising ceramic hydroxyapatite particles
US6579516B1 (en) 1995-06-13 2003-06-17 Zahra Mansouri Methods of delivering materials into the skin, and compositions used therein
US7655250B2 (en) 1995-06-13 2010-02-02 Laboratory Skin Care, Inc. Topical formulations comprising ceramic hydroxyapatite particles
US5700842A (en) * 1995-11-01 1997-12-23 Kimberly-Clark Worldwide, Inc. Methods of incorporating a hydrophobic substance into an aqueous solution
US5888524A (en) * 1995-11-01 1999-03-30 Kimberly-Clark Worldwide, Inc. Antimicrobial compositions and wet wipes including the same
US6080417A (en) * 1996-03-27 2000-06-27 Antiseptica Chemisch-Pharmazeutische Produkte Gmbh Hand disinfectant
WO1997035475A1 (fr) * 1996-03-27 1997-10-02 Antiseptica Chemisch-Pharmazeutische Produkte Gmbh Agent desinfectant pour les mains
WO1997046218A3 (fr) * 1996-06-04 1998-03-12 Ciba Sc Holding Ag Formulations liquides concentrees comprenant un principe actif microbicide
US6358906B1 (en) 1996-06-04 2002-03-19 Ciba Specialty Chemicals Corporation Concentrated liquid accumulations comprising a microbicidally active ingredient
CN1133418C (zh) * 1996-06-04 2004-01-07 西巴特殊化学品控股有限公司 含有杀微生物的活性成分的浓缩液体制剂
WO1997046218A2 (fr) * 1996-06-04 1997-12-11 Ciba Specialty Chemicals Holding Inc. Formulations liquides concentrees comprenant un principe actif microbicide
WO1998001110A1 (fr) * 1996-07-10 1998-01-15 Calgon Vestal, Inc. Produit de lavage pour la peau a base de triclosan et possedant une meilleure efficacite
US5955408A (en) * 1996-07-10 1999-09-21 Steris Inc. Triclosan skin wash with enhanced efficacy
US6090772A (en) * 1996-07-10 2000-07-18 Steris Inc Triclosan skin wash with enhanced efficacy
US6531434B1 (en) * 1997-05-20 2003-03-11 Novapharm Research (Australia) Pty. Alkylpolyglucosides containing disinfectant compositions active against pseudomonas microorganism
US7163914B2 (en) 1997-05-20 2007-01-16 Novapharm Research (Australia) Pty. Ltd. Alkylpolyglucosides containing disinfectant compositions active against pseudomonas microorganism
EP0882446A1 (fr) * 1997-06-02 1998-12-09 Gojo Industries,Inc. Compositions antimicrobiennes pour le nettoyage de la peau
US7566740B2 (en) * 1998-10-06 2009-07-28 Bml Pharmaceuticals, Inc. Method of treating mucositis
WO2000048554A2 (fr) * 1999-02-16 2000-08-24 Ecolab Inc. Compositions synergiques antimicrobiennes de nettoyage de la peau
WO2000048554A3 (fr) * 1999-02-16 2000-11-02 Ecolab Inc Compositions synergiques antimicrobiennes de nettoyage de la peau
EP1044686A1 (fr) * 1999-04-12 2000-10-18 Laboratoires Gilbert SA Solution de chlorhexidine alcoolique colorée et sa méthode de fabrication
FR2791890A1 (fr) * 1999-04-12 2000-10-13 Gilbert Lab Solution de chlorhexidine alcoolique coloree et sa methode de fabrication
WO2001064034A1 (fr) * 1999-05-19 2001-09-07 Stack, Kevin Lotion desinfectante antimicrobienne avec des proprietes de protection de la peau
AU2005209647B2 (en) * 1999-12-13 2008-10-02 Ethicon, Inc. Deep penetrating antimicrobial compositions
WO2001041567A1 (fr) * 1999-12-13 2001-06-14 Ethicon, Inc. Compositions antimicrobiennes a forte penetration
WO2004101725A1 (fr) * 2003-05-15 2004-11-25 Greenbridge Environmental Control Limited Composition de nettoyage antivirale
WO2004101726A3 (fr) * 2003-05-15 2005-03-17 Greenbridge Environmental Cont Preparation nettoyante anti-virale et anti-bacterienne
US7915216B2 (en) 2003-05-15 2011-03-29 Medigreen Ood Anti-viral and anti-bacterial cleaning composition
WO2006062846A3 (fr) * 2004-12-09 2007-01-18 Dial Corp Compositions presentant une efficacite antivirale et antibacterienne elevee
WO2006062897A3 (fr) * 2004-12-09 2007-01-18 Dial Corp Compositions presentant une efficacite antivirale et antibacterienne elevee
WO2006062897A2 (fr) * 2004-12-09 2006-06-15 The Dial Corporation Compositions presentant une efficacite antivirale et antibacterienne elevee
WO2006062846A2 (fr) * 2004-12-09 2006-06-15 The Dial Corporation Compositions presentant une efficacite antivirale et antibacterienne elevee
DE102004062775A1 (de) * 2004-12-21 2006-06-29 Stockhausen Gmbh Alkoholischer Pumpschaum
US7670615B2 (en) 2004-12-21 2010-03-02 Stockhausen Gmbh Alcoholic pump foam
WO2012119644A1 (fr) * 2011-03-08 2012-09-13 Sca Hygiene Products Ab Composition nettoyante antimicrobienne pauvre en alcool

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